Published in Trends Genet on November 29, 2010
Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet (2013) 7.44
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Interpreting noncoding genetic variation in complex traits and human disease. Nat Biotechnol (2012) 3.01
Cost-effective, high-throughput DNA sequencing libraries for multiplexed target capture. Genome Res (2012) 2.91
Genome-wide association study dissects the genetic architecture of oil biosynthesis in maize kernels. Nat Genet (2012) 2.25
Heritability and genomics of gene expression in peripheral blood. Nat Genet (2014) 2.00
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Expression quantitative trait loci analysis identifies associations between genotype and gene expression in human intestine. Gastroenterology (2013) 1.69
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Genetic variants contribute to gene expression variability in humans. Genetics (2012) 1.20
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Impact of common regulatory single-nucleotide variants on gene expression profiles in whole blood. Eur J Hum Genet (2012) 1.15
The genetic and mechanistic basis for variation in gene regulation. PLoS Genet (2015) 1.10
Age-specific variation in immune response in Drosophila melanogaster has a genetic basis. Genetics (2012) 1.05
Global properties and functional complexity of human gene regulatory variation. PLoS Genet (2013) 1.02
Bayesian detection of expression quantitative trait loci hot spots. Genetics (2011) 1.00
Using next-generation RNA sequencing to identify imprinted genes. Heredity (Edinb) (2014) 0.99
Whole transcriptome RNA-Seq allelic expression in human brain. BMC Genomics (2013) 0.99
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Genomic modulators of the immune response. Trends Genet (2012) 0.94
Allele-specific binding of ZFP57 in the epigenetic regulation of imprinted and non-imprinted monoallelic expression. Genome Biol (2015) 0.91
Identification and characterization of transcript polymorphisms in soybean lines varying in oil composition and content. BMC Genomics (2014) 0.90
A genomic portrait of the genetic architecture and regulatory impact of microRNA expression in response to infection. Genome Res (2014) 0.90
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Allele-specific expression and eQTL analysis in mouse adipose tissue. BMC Genomics (2014) 0.89
A meta-analysis of gene expression quantitative trait loci in brain. Transl Psychiatry (2014) 0.87
Gene expression in large pedigrees: analytic approaches. BMC Genet (2016) 0.87
Resolving the variable genome and epigenome in human disease. J Intern Med (2012) 0.85
Genome-wide association study of behavioral, physiological and gene expression traits in outbred CFW mice. Nat Genet (2016) 0.84
The impact of 3'UTR variants on differential expression of candidate cancer susceptibility genes. PLoS One (2013) 0.84
Genetic architecture of retinal and macular degenerative diseases: the promise and challenges of next-generation sequencing. Genome Med (2013) 0.83
Natural genetic variation impacts expression levels of coding, non-coding, and antisense transcripts in fission yeast. Mol Syst Biol (2014) 0.83
Gene-gene interaction and functional impact of polymorphisms on innate immune genes in controlling Plasmodium falciparum blood infection level. PLoS One (2012) 0.83
Integrative Multi-omic Analysis of Human Platelet eQTLs Reveals Alternative Start Site in Mitofusin 2. Am J Hum Genet (2016) 0.83
Genes controlling vaccine responses and disease resistance to respiratory viral pathogens in cattle. Vet Immunol Immunopathol (2011) 0.82
Genetic variation of pre-mRNA alternative splicing in human populations. Wiley Interdiscip Rev RNA (2011) 0.82
Liver expression quantitative trait loci: a foundation for pharmacogenomic research. Front Genet (2012) 0.82
Drosophila melanogaster as a model for lead neurotoxicology and toxicogenomics research. Front Genet (2012) 0.81
The potential of the riboSNitch in personalized medicine. Wiley Interdiscip Rev RNA (2015) 0.81
Cd14 SNPs regulate the innate immune response. Mol Immunol (2012) 0.80
Mapping of hepatic expression quantitative trait loci (eQTLs) in a Han Chinese population. J Med Genet (2014) 0.80
Expression quantitative trait locus analysis for translational medicine. Genome Med (2015) 0.80
Recommendations for Accurate Resolution of Gene and Isoform Allele-Specific Expression in RNA-Seq Data. PLoS One (2015) 0.80
Efficiently identifying significant associations in genome-wide association studies. J Comput Biol (2013) 0.80
Long non-coding RNA-mediated regulation of glucose homeostasis and diabetes. Am J Cardiovasc Dis (2016) 0.79
A uniform survey of allele-specific binding and expression over 1000-Genomes-Project individuals. Nat Commun (2016) 0.79
Extensive allele-specific translational regulation in hybrid mice. Mol Syst Biol (2015) 0.79
dcVar: a method for identifying common variants that modulate differential correlation structures in gene expression data. Front Genet (2015) 0.79
Predominant contribution of cis-regulatory divergence in the evolution of mouse alternative splicing. Mol Syst Biol (2015) 0.78
Single nucleotide variants in transcription factors associate more tightly with phenotype than with gene expression. PLoS Genet (2014) 0.78
Novel insights into the regulatory architecture of CD4+ T cells in rheumatoid arthritis. PLoS One (2014) 0.78
Approach to epigenetic analysis in language disorders. J Neurodev Disord (2011) 0.78
Allelome.PRO, a pipeline to define allele-specific genomic features from high-throughput sequencing data. Nucleic Acids Res (2015) 0.77
Natural variation in non-coding regions underlying phenotypic diversity in budding yeast. Sci Rep (2016) 0.77
Transcriptional and Linkage Analyses Identify Loci that Mediate the Differential Macrophage Response to Inflammatory Stimuli and Infection. PLoS Genet (2015) 0.77
Elucidating the molecular responses of apple rootstock resistant to ARD pathogens: challenges and opportunities for development of genomics-assisted breeding tools. Hortic Res (2014) 0.76
Next generation sequencing technology and genomewide data analysis: Perspectives for retinal research. Prog Retin Eye Res (2016) 0.76
Model based heritability scores for high-throughput sequencing data. BMC Bioinformatics (2017) 0.75
Disease Risk Assessment Using a Voronoi-Based Network Analysis of Genes and Variants Scores. Front Genet (2017) 0.75
ulfasQTL: an ultra-fast method of composite splicing QTL analysis. BMC Genomics (2017) 0.75
Mapping eQTLs with RNA-Seq Reveals Novel Susceptibility Genes, Non-Coding RNAs, and Alternative-Splicing Events in Systemic Lupus Erythematosus. Hum Mol Genet (2017) 0.75
Transcriptome sequencing study implicates immune-related genes differentially expressed in schizophrenia: new data and a meta-analysis. Transl Psychiatry (2017) 0.75
Transcriptome changes in apple peel tissues during CO2 injury symptom development under controlled atmosphere storage regimens. Hortic Res (2015) 0.75
Hypothalamic transcriptomes of 99 mouse strains reveal trans eQTL hotspots, splicing QTLs and novel non-coding genes. Elife (2016) 0.75
Bayesian Inference of Allele-Specific Gene Expression Indicates Abundant cis-regulatory Variation in Natural Flycatcher Populations. Genome Biol Evol (2017) 0.75
C-reactive protein upregulates the whole blood expression of CD59 - an integrative analysis. PLoS Comput Biol (2017) 0.75
Using RNA-seq data to select reference genes for normalizing gene expression in apple roots. PLoS One (2017) 0.75
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet (2012) 7.59
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48
Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Nat Genet (2009) 5.32
Global patterns of cis variation in human cells revealed by high-density allelic expression analysis. Nat Genet (2009) 4.72
Targeted screening of cis-regulatory variation in human haplotypes. Genome Res (2008) 3.10
Survey of allelic expression using EST mining. Genome Res (2005) 2.67
Genome-wide association study identifies variants at 9p21 and 22q13 associated with development of cutaneous nevi. Nat Genet (2009) 2.65
Allele-specific chromatin remodeling in the ZPBP2/GSDMB/ORMDL3 locus associated with the risk of asthma and autoimmune disease. Am J Hum Genet (2009) 2.56
A probabilistic approach for SNP discovery in high-throughput human resequencing data. Genome Res (2009) 2.55
Use of genome-wide association studies for drug repositioning. Nat Biotechnol (2012) 2.51
An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits. PLoS Genet (2010) 2.43
Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk. PLoS Genet (2013) 2.39
Spectrum of mutations in MMACHC, allelic expression, and evidence for genotype-phenotype correlations. Hum Mutat (2009) 2.34
Population genomics in a disease targeted primary cell model. Genome Res (2009) 2.20
A genome-wide association study reveals variants in ARL15 that influence adiponectin levels. PLoS Genet (2009) 2.09
The relationship between DNA methylation, genetic and expression inter-individual variation in untransformed human fibroblasts. Genome Biol (2014) 2.01
A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5. Hum Mol Genet (2008) 1.98
Homozygous BUB1B mutation and susceptibility to gastrointestinal neoplasia. N Engl J Med (2010) 1.90
Mapping of numerous disease-associated expression polymorphisms in primary peripheral blood CD4+ lymphocytes. Hum Mol Genet (2010) 1.89
Tissue effect on genetic control of transcript isoform variation. PLoS Genet (2009) 1.59
Assessment of gene-by-sex interaction effect on bone mineral density. J Bone Miner Res (2012) 1.58
RNA sequencing reveals the role of splicing polymorphisms in regulating human gene expression. Genome Res (2010) 1.58
Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia. Genome Biol (2013) 1.57
The effect of polymorphisms in the enhancer of split gene complex on bristle number variation in a large wild-caught cohort of Drosophila melanogaster. Genetics (2005) 1.52
Global analysis of the impact of environmental perturbation on cis-regulation of gene expression. PLoS Genet (2011) 1.51
Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry. PLoS Genet (2011) 1.47
Genome-wide assessment of imprinted expression in human cells. Genome Biol (2011) 1.22
Cell culture-induced aberrant methylation of the imprinted IG DMR in human lymphoblastoid cell lines. Epigenetics (2010) 1.12
No evidence for an association between common nonsynonymous polymorphisms in delta and bristle number variation in natural and laboratory populations of Drosophila melanogaster. Genetics (2004) 1.10
Systematic assessment of the human osteoblast transcriptome in resting and induced primary cells. Physiol Genomics (2008) 1.09
HLA class II associated risk and protection against multiple sclerosis-a Finnish family study. J Neuroimmunol (2002) 1.07
Intercellular adhesion molecule-1 K469E polymorphism: study of association with multiple sclerosis. Hum Immunol (2003) 1.05
Mapping cis-acting regulatory variation in recombinant congenic strains. Physiol Genomics (2006) 1.00
A low-cost open-source SNP genotyping platform for association mapping applications. Genome Biol (2005) 1.00
Integration of high-resolution methylome and transcriptome analyses to dissect epigenomic changes in childhood acute lymphoblastic leukemia. Cancer Res (2013) 0.99
Computational analysis of whole-genome differential allelic expression data in human. PLoS Comput Biol (2010) 0.99
Analysis of expressed SNPs identifies variable extents of expression from the human inactive X chromosome. Genome Biol (2013) 0.99
Powerful identification of cis-regulatory SNPs in human primary monocytes using allele-specific gene expression. PLoS One (2012) 0.98
Interaction between genetic and epigenetic variation defines gene expression patterns at the asthma-associated locus 17q12-q21 in lymphoblastoid cell lines. Hum Genet (2012) 0.98
A cis-acting regulatory variant in the IL2RA locus. J Immunol (2009) 0.89
Global identification of conserved post-transcriptional regulatory programs in trypanosomatids. Nucleic Acids Res (2013) 0.85
Genome-wide association study of age at menarche in African-American women. Hum Mol Genet (2013) 0.85
Genotype-based test in mapping cis-regulatory variants from allele-specific expression data. PLoS One (2012) 0.84
Genome-wide search for exonic variants affecting translational efficiency. Nat Commun (2013) 0.82
Promoter polymorphisms in CHI3L1 are associated with asthma. J Allergy Clin Immunol (2012) 0.82
Vitamin D receptor 3' haplotypes are unequally expressed in primary human bone cells and associated with increased fracture risk: the MrOS Study in Sweden and Hong Kong. J Bone Miner Res (2007) 0.81
Patterns of variation in DNA segments upstream of transcription start sites. Hum Mutat (2007) 0.80
Fine mapping of the insulin-induced gene 2 identifies a variant associated with LDL cholesterol and total apolipoprotein B levels. Circ Cardiovasc Genet (2010) 0.80
Epigenetic modification of the gene for the vitamin B(12) chaperone MMACHC can result in increased tumorigenicity and methionine dependence. Mol Genet Metab (2009) 0.79
Reply to Rational drug repositioning by medical genetics. Nat Biotechnol (2013) 0.78
The commercialization of genomic research in Canada. Healthc Policy (2010) 0.77
Phosphodiesterase type 4D gene polymorphism: association with the response to short-acting bronchodilators in paediatric asthma patients. Mediators Inflamm (2011) 0.76
Human genetics in full resolution. Genome Biol (2011) 0.75
Erratum: Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants. Nat Commun (2015) 0.75