Published in Hum Mol Genet on September 10, 2010
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The autoimmunity-associated BLK haplotype exhibits cis-regulatory effects on mRNA and protein expression that are prominently observed in B cells early in development. Hum Mol Genet (2012) 0.97
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Genome-wide association study of recalcitrant atopic dermatitis in Korean children. J Allergy Clin Immunol (2015) 0.77
Predictive value of STMN1 gene promoter polymorphism (-2166T>C) in patients with advanced NSCLC treated with the combination of platinum compounds and vinorelbine. Cancer Chemother Pharmacol (2015) 0.77
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17q21 asthma-risk variants switch CTCF binding and regulate IL-2 production by T cells. Nat Commun (2016) 0.76
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Gene expression profiling of asthma phenotypes demonstrates molecular signatures of atopy and asthma control. J Allergy Clin Immunol (2016) 0.75
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Functional interactors of three genome-wide association study genes are differentially expressed in severe chronic obstructive pulmonary disease lung tissue. Sci Rep (2017) 0.75
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Autoimmune risk variants in ERAP2 are associated with gene-expression levels in thymus. Genes Immun (2016) 0.75
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Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet (2008) 30.20
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science (2006) 27.49
Genetic dissection of transcriptional regulation in budding yeast. Science (2002) 25.01
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Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature (2007) 14.43
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A survey of genetic human cortical gene expression. Nat Genet (2007) 12.04
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Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes. Nat Genet (2007) 11.09
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High-resolution mapping of expression-QTLs yields insight into human gene regulation. PLoS Genet (2008) 9.68
Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. N Engl J Med (2008) 9.61
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Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction. Nat Genet (2009) 6.83
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Evaluation of genetic variation contributing to differences in gene expression between populations. Am J Hum Genet (2008) 4.01
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Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein. Am J Hum Genet (2008) 3.61
Sequence polymorphisms cause many false cis eQTLs. PLoS One (2007) 3.54
Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease. Nat Genet (2008) 3.36
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A novel susceptibility locus for type 1 diabetes on Chr12q13 identified by a genome-wide association study. Diabetes (2008) 2.90
Large-scale in silico and microarray-based identification of direct 1,25-dihydroxyvitamin D3 target genes. Mol Endocrinol (2005) 2.73
Allele-specific chromatin remodeling in the ZPBP2/GSDMB/ORMDL3 locus associated with the risk of asthma and autoimmune disease. Am J Hum Genet (2009) 2.56
The clustering of other chronic inflammatory diseases in inflammatory bowel disease: a population-based study. Gastroenterology (2005) 2.29
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Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell (2005) 18.20
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Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet (2012) 7.59
Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program. Am J Respir Crit Care Med (2009) 7.17
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Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48
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Use of beclomethasone dipropionate as rescue treatment for children with mild persistent asthma (TREXA): a randomised, double-blind, placebo-controlled trial. Lancet (2011) 5.42
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Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease. Nat Med (2008) 4.70
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