Mapping of hepatic expression quantitative trait loci (eQTLs) in a Han Chinese population.

PubWeight™: 0.80‹?›

🔗 View Article (PMC 3995251)

Published in J Med Genet on March 24, 2014

Authors

Xiaoliang Wang1, Huamei Tang, Mujian Teng, Zhiqiang Li, Jianguo Li, Junwei Fan, Lin Zhong, Xing Sun, Junming Xu, Guoqing Chen, Dawei Chen, Zhaowen Wang, Tonghai Xing, Jinyan Zhang, Li Huang, Shuyun Wang, Xiao Peng, Shengying Qin, Yongyong Shi, Zhihai Peng

Author Affiliations

1: Department of General Surgery, Shanghai First People's Hospital, Medical College, Shanghai Jiaotong University, Shanghai, China.

Articles cited by this

A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics (2003) 82.89

A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet (2009) 30.09

Mapping the genetic architecture of gene expression in human liver. PLoS Biol (2008) 19.44

Integrated genotype calling and association analysis of SNPs, common copy number polymorphisms and rare CNVs. Nat Genet (2008) 15.89

Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS. PLoS Genet (2010) 10.75

High-resolution mapping of expression-QTLs yields insight into human gene regulation. PLoS Genet (2008) 9.68

The landscape of genetic complexity across 5,700 gene expression traits in yeast. Proc Natl Acad Sci U S A (2005) 9.66

Genetical genomics: the added value from segregation. Trends Genet (2001) 8.23

arrayQualityMetrics--a bioconductor package for quality assessment of microarray data. Bioinformatics (2008) 5.95

Improved whole-chromosome phasing for disease and population genetic studies. Nat Methods (2013) 5.43

A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians. Nat Genet (2009) 5.29

Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits. PLoS Genet (2011) 3.92

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet (2011) 3.18

A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort. Genome Res (2011) 3.00

Identification, replication, and functional fine-mapping of expression quantitative trait loci in primary human liver tissue. PLoS Genet (2011) 2.68

The alcohol flushing response: an unrecognized risk factor for esophageal cancer from alcohol consumption. PLoS Med (2009) 2.20

Using probabilistic estimation of expression residuals (PEER) to obtain increased power and interpretability of gene expression analyses. Nat Protoc (2012) 2.14

A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population. Hum Mol Genet (2011) 1.96

The study of eQTL variations by RNA-seq: from SNPs to phenotypes. Trends Genet (2010) 1.94

Large differences in testosterone excretion in Korean and Swedish men are strongly associated with a UDP-glucuronosyl transferase 2B17 polymorphism. J Clin Endocrinol Metab (2005) 1.68

Genome-wide association study confirming association of HLA-DP with protection against chronic hepatitis B and viral clearance in Japanese and Korean. PLoS One (2012) 1.44

UDP-glucuronosyltransferase (UGT1A1*28 and UGT1A6*2) polymorphisms in Caucasians and Asians: relationships to serum bilirubin concentrations. Pharmacogenetics (1999) 1.41

Epidemiology of hepatitis B infection in the Western Pacific and South East Asia. Gut (1996) 1.38

Ontogeny of human hepatic cytochromes P450. J Biochem Mol Toxicol (2007) 1.36

Genomics of ADME gene expression: mapping expression quantitative trait loci relevant for absorption, distribution, metabolism and excretion of drugs in human liver. Pharmacogenomics J (2011) 1.31

FstSNP-HapMap3: a database of SNPs with high population differentiation for HapMap3. Bioinformation (2008) 1.12

GWAPower: a statistical power calculation software for genome-wide association studies with quantitative traits. BMC Genet (2011) 1.04

A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk. Gut (2013) 0.94

Pharmacogenetics of P450 oxidoreductase: implications in drug metabolism and therapy. Pharmacogenet Genomics (2012) 0.90

SNPs affecting serum metabolomic traits may regulate gene transcription and lipid accumulation in the liver. Metabolism (2012) 0.86

A genome-wide assessment of variability in human serum metabolism. Hum Mutat (2013) 0.86

Impact of the Interaction between 3'-UTR SNPs and microRNA on the Expression of Human Xenobiotic Metabolism Enzyme and Transporter Genes. Front Genet (2012) 0.84

Bivariate genome-wide association study suggests fatty acid desaturase genes and cadherin DCHS2 for variation of both compressive strength index and appendicular lean mass in males. Bone (2012) 0.80

Genome-wide association study of serum albumin:globulin ratio in Korean populations. J Hum Genet (2013) 0.79

Articles by these authors

A human gut microbial gene catalogue established by metagenomic sequencing. Nature (2010) 43.63

The sequence and de novo assembly of the giant panda genome. Nature (2009) 15.76

Sequencing of 50 human exomes reveals adaptation to high altitude. Science (2010) 11.27

Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha. Science (2009) 10.78

Identification of loci associated with schizophrenia by genome-wide association and follow-up. Nat Genet (2008) 10.52

ESR1 ligand-binding domain mutations in hormone-resistant breast cancer. Nat Genet (2013) 4.03

MicroRNA-mediated control of cell fate in megakaryocyte-erythrocyte progenitors. Dev Cell (2008) 3.84

Risk of COPD from exposure to biomass smoke: a metaanalysis. Chest (2010) 3.46

The 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia-dependent aortic aneurysm. Nat Med (2004) 3.34

Dendritic cell apoptosis in the maintenance of immune tolerance. Science (2006) 3.33

Genome-wide association study identifies susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21 and 9q33.3. Nat Genet (2010) 3.02

Enterovirus 71 outbreak in the People's Republic of China in 2008. J Clin Microbiol (2009) 2.98

A partition-ligation-combination-subdivision EM algorithm for haplotype inference with multiallelic markers: update of the SHEsis (http://analysis.bio-x.cn). Cell Res (2009) 2.86

A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese. Nat Genet (2011) 2.85

Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis. Oncogene (2003) 2.79

Foxp3 exploits a pre-existent enhancer landscape for regulatory T cell lineage specification. Cell (2012) 2.79

Intermittent hypoxia increases insulin resistance in genetically obese mice. J Physiol (2003) 2.71

Chronic intermittent hypoxia induces atherosclerosis. Am J Respir Crit Care Med (2007) 2.62

A complete sequence of the T. tengcongensis genome. Genome Res (2002) 2.60

Six1 is required for the early organogenesis of mammalian kidney. Development (2003) 2.47

Transcription factor Sp1 expression is a significant predictor of survival in human gastric cancer. Clin Cancer Res (2003) 2.38

Pax3 functions at a nodal point in melanocyte stem cell differentiation. Nature (2005) 2.37

Chronic intermittent hypoxia causes hepatitis in a mouse model of diet-induced fatty liver. Am J Physiol Gastrointest Liver Physiol (2007) 2.28

The role of Six1 in mammalian auditory system development. Development (2003) 2.22

Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease. Nat Genet (2012) 2.17

Intermittent hypoxia causes insulin resistance in lean mice independent of autonomic activity. Am J Respir Crit Care Med (2007) 2.09

Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome. Nat Genet (2012) 2.02

Development of a virus-induced gene-silencing system for hexaploid wheat and its use in functional analysis of the Lr21-mediated leaf rust resistance pathway. Plant Physiol (2005) 2.02

A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at 3q13.31 and 5p13.1. Nat Genet (2011) 1.98

Effect of myriocin on plasma sphingolipid metabolism and atherosclerosis in apoE-deficient mice. J Biol Chem (2004) 1.95

The Use of Opioid Analgesics following Common Upper Extremity Surgical Procedures: A National, Population-Based Study. Plast Reconstr Surg (2016) 1.94

Interleukin-6-driven progranulin expression increases cholangiocarcinoma growth by an Akt-dependent mechanism. Gut (2011) 1.91

Common variants on 8p12 and 1q24.2 confer risk of schizophrenia. Nat Genet (2011) 1.88

GWAS identifies novel susceptibility loci on 6p21.32 and 21q21.3 for hepatocellular carcinoma in chronic hepatitis B virus carriers. PLoS Genet (2012) 1.86

Refractive error and visual impairment in school children in rural southern China. Ophthalmology (2006) 1.84

Serine palmitoyl-CoA transferase (SPT) deficiency and sphingolipid levels in mice. Biochim Biophys Acta (2005) 1.77

Inhibition of HIV-1 maturation via drug association with the viral Gag protein in immature HIV-1 particles. J Biol Chem (2005) 1.66

A network of multi-tasking proteins at the DNA replication fork preserves genome stability. PLoS Genet (2005) 1.61

Dyslipidemia and atherosclerosis induced by chronic intermittent hypoxia are attenuated by deficiency of stearoyl coenzyme A desaturase. Circ Res (2008) 1.61

Chronic intermittent hypoxia predisposes to liver injury. Hepatology (2007) 1.57

Intussusception in infants younger than 3 months: a single center's experience. World J Pediatr (2010) 1.57

MicroRNA-143 as a tumor suppressor for bladder cancer. J Urol (2009) 1.56

The gene Sr33, an ortholog of barley Mla genes, encodes resistance to wheat stem rust race Ug99. Science (2013) 1.55

Coxsackievirus A21, enterovirus 68, and acute respiratory tract infection, China. Emerg Infect Dis (2012) 1.52

Assessment and prognostic significance of mitotic index using the mitosis marker phospho-histone H3 in low and intermediate-grade infiltrating astrocytomas. Am J Surg Pathol (2006) 1.50

Association analyses identify multiple new lung cancer susceptibility loci and their interactions with smoking in the Chinese population. Nat Genet (2012) 1.49

Chronic intermittent hypoxia and acetaminophen induce synergistic liver injury in mice. Exp Physiol (2008) 1.48

Effect of intermittent hypoxia on atherosclerosis in apolipoprotein E-deficient mice. Atherosclerosis (2009) 1.48

The endothelial nitric oxide synthase gene is associated with coronary artery disease: a meta-analysis. Cardiology (2010) 1.47

Activation of estrogen receptor-alpha by the anion nitrite. Cancer Res (2008) 1.47

Expression and role of neuroglobin in rats with sepsis-associated encephalopathy. Crit Care Med (2014) 1.46

Retracted Association of CYP2A6*4 with susceptibility of lung cancer: a meta-analysis. PLoS One (2013) 1.45

A novel FoxM1-caveolin signaling pathway promotes pancreatic cancer invasion and metastasis. Cancer Res (2011) 1.45

Genome analyses of Icelandic strains of Sulfolobus islandicus, model organisms for genetic and virus-host interaction studies. J Bacteriol (2011) 1.45

Arabidopsis acyl-CoA-binding protein ACBP3 participates in plant response to hypoxia by modulating very-long-chain fatty acid metabolism. Plant J (2014) 1.44

Enhanced presynaptic neurotransmitter release in the anterior cingulate cortex of mice with chronic pain. J Neurosci (2006) 1.43

In situ imaging of the conducting filament in a silicon oxide resistive switch. Sci Rep (2012) 1.43

SHEsisEpi, a GPU-enhanced genome-wide SNP-SNP interaction scanning algorithm, efficiently reveals the risk genetic epistasis in bipolar disorder. Cell Res (2010) 1.42

Prognostic role of serum carbohydrate antigen 19-9 levels in patients with resectable hepatocellular carcinoma. Tumour Biol (2015) 1.42

Reconstruction of the Irradiated Breast: A National Claims-Based Assessment of Postoperative Morbidity. Plast Reconstr Surg (2017) 1.40

Retracted Drug-eluting stents for acute coronary syndrome: a meta-analysis of randomized controlled trials. PLoS One (2013) 1.39

Combination of channel-TURP and ILC versus standard TURP or ILC for elderly with benign prostatic hyperplasia: a randomized prospective trial. Urol Int (2011) 1.39

Differential role of opioid receptors in tibial nerve inhibition of nociceptive and nonnociceptive bladder reflexes in cats. Am J Physiol Renal Physiol (2012) 1.38

Functional variants in the promoter region of Chitinase 3-like 1 (CHI3L1) and susceptibility to schizophrenia. Am J Hum Genet (2006) 1.37

Retracted Association of Polymorphism rs198977 in Human Kallikrein-2 Gene (KLK2) with Susceptibility of Prostate Cancer: A Meta-Analysis. PLoS One (2013) 1.37

The critical roles of platelet activation and reduced NO bioavailability in fatal pulmonary arterial hypertension in a murine hemolysis model. Blood (2010) 1.35

The farnesoid X receptor controls gene expression in a ligand- and promoter-selective fashion. J Biol Chem (2003) 1.35

Guggulsterone is a farnesoid X receptor antagonist in coactivator association assays but acts to enhance transcription of bile salt export pump. J Biol Chem (2003) 1.33

Intermittent hypoxia exacerbates metabolic effects of diet-induced obesity. Obesity (Silver Spring) (2011) 1.32

Coupled dictionary training for image super-resolution. IEEE Trans Image Process (2012) 1.30

De novo assembly and characterization of fruit transcriptome in Litchi chinensis Sonn and analysis of differentially regulated genes in fruit in response to shading. BMC Genomics (2013) 1.30

Construction of a SNP-based genetic linkage map in cultivated peanut based on large scale marker development using next-generation double-digest restriction-site-associated DNA sequencing (ddRADseq). BMC Genomics (2014) 1.30

IMP3 is a novel prognostic marker that correlates with colon cancer progression and pathogenesis. Ann Surg Oncol (2009) 1.29

Imaging stacking order in few-layer graphene. Nano Lett (2010) 1.28

Identification of recurrence-related microRNAs in hepatocellular carcinoma following liver transplantation. Mol Oncol (2012) 1.28

Sphingomyelin synthase 2 deficiency attenuates NFkappaB activation. Arterioscler Thromb Vasc Biol (2008) 1.28

Phospholipid transfer protein deficiency impairs apolipoprotein-B secretion from hepatocytes by stimulating a proteolytic pathway through a relative deficiency of vitamin E and an increase in intracellular oxidants. J Biol Chem (2005) 1.27

Deficiency of Bim in dendritic cells contributes to overactivation of lymphocytes and autoimmunity. Blood (2007) 1.27

Genetic polymorphism analysis of CYP2C19 in Chinese Han populations from different geographic areas of mainland China. Pharmacogenomics (2008) 1.26

Anti-AIDS agents. 78. Design, synthesis, metabolic stability assessment, and antiviral evaluation of novel betulinic acid derivatives as potent anti-human immunodeficiency virus (HIV) agents. J Med Chem (2009) 1.26

Exploring off-targets and off-systems for adverse drug reactions via chemical-protein interactome--clozapine-induced agranulocytosis as a case study. PLoS Comput Biol (2011) 1.26

Sulfolobus tengchongensis spindle-shaped virus STSV1: virus-host interactions and genomic features. J Virol (2005) 1.26

Anti-AIDS agents 69. Moronic acid and other triterpene derivatives as novel potent anti-HIV agents. J Med Chem (2006) 1.25