Published in PLoS Genet on May 30, 2013
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Genetic interactions between polymorphisms that affect gene expression in yeast. Nature (2005) 6.42
DNase I sensitivity QTLs are a major determinant of human expression variation. Nature (2012) 6.17
The architecture of gene regulatory variation across multiple human tissues: the MuTHER study. PLoS Genet (2011) 5.95
Heritable individual-specific and allele-specific chromatin signatures in humans. Science (2010) 5.94
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Genomic surveys by methylation-sensitive SNP analysis identify sequence-dependent allele-specific DNA methylation. Nat Genet (2008) 5.66
Patterns of cis regulatory variation in diverse human populations. PLoS Genet (2012) 5.28
Tissue-specific genetic control of splicing: implications for the study of complex traits. PLoS Biol (2008) 5.08
Genetic analysis of human traits in vitro: drug response and gene expression in lymphoblastoid cell lines. PLoS Genet (2008) 5.08
Candidate causal regulatory effects by integration of expression QTLs with complex trait genetic associations. PLoS Genet (2010) 4.95
Defining mechanisms that regulate RNA polymerase II transcription in vivo. Nature (2009) 4.31
Base-resolution analyses of sequence and parent-of-origin dependent DNA methylation in the mouse genome. Cell (2012) 4.00
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Genetics of gene expression in primary immune cells identifies cell type-specific master regulators and roles of HLA alleles. Nat Genet (2012) 3.77
Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA. PLoS Genet (2011) 3.65
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Learning a prior on regulatory potential from eQTL data. PLoS Genet (2009) 3.31
Gene expression in skin and lymphoblastoid cells: Refined statistical method reveals extensive overlap in cis-eQTL signals. Am J Hum Genet (2010) 3.28
A Bayesian framework to account for complex non-genetic factors in gene expression levels greatly increases power in eQTL studies. PLoS Comput Biol (2010) 3.23
Allelic skewing of DNA methylation is widespread across the genome. Am J Hum Genet (2010) 3.17
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A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort. Genome Res (2011) 3.00
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Genetic analysis of variation in transcription factor binding in yeast. Nature (2010) 2.69
Genetical genomics: spotlight on QTL hotspots. PLoS Genet (2008) 2.63
Single-tissue and cross-tissue heritability of gene expression via identity-by-descent in related or unrelated individuals. PLoS Genet (2011) 2.53
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Polymorphic cis- and trans-regulation of human gene expression. PLoS Biol (2010) 2.42
Common polymorphic transcript variation in human disease. Genome Res (2009) 2.35
Genetic analysis of radiation-induced changes in human gene expression. Nature (2009) 2.30
Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression. PLoS Genet (2012) 2.29
Extreme clonality in lymphoblastoid cell lines with implications for allele specific expression analyses. PLoS One (2008) 2.28
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Effects of cis and trans genetic ancestry on gene expression in African Americans. PLoS Genet (2008) 2.09
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Identification of common genetic variants that account for transcript isoform variation between human populations. Hum Genet (2008) 1.96
The study of eQTL variations by RNA-seq: from SNPs to phenotypes. Trends Genet (2010) 1.94
The asthma-associated ORMDL3 gene product regulates endoplasmic reticulum-mediated calcium signaling and cellular stress. Hum Mol Genet (2010) 1.83
Allele-specific DNA methylation in mouse strains is mainly determined by cis-acting sequences. Genome Res (2009) 1.80
Inherited variation in gene expression. Annu Rev Genomics Hum Genet (2009) 1.80
Deciphering the genetic architecture of variation in the immune response to Mycobacterium tuberculosis infection. Proc Natl Acad Sci U S A (2012) 1.73
Widespread site-dependent buffering of human regulatory polymorphism. PLoS Genet (2012) 1.72
seeQTL: a searchable database for human eQTLs. Bioinformatics (2011) 1.72
Allele-specific chromatin immunoprecipitation studies show genetic influence on chromatin state in human genome. PLoS Genet (2007) 1.71
Identification of cis- and trans-regulatory variation modulating microRNA expression levels in human fibroblasts. Genome Res (2010) 1.67
Non-imprinted allele-specific DNA methylation on human autosomes. Genome Biol (2009) 1.64
RNA sequencing reveals the role of splicing polymorphisms in regulating human gene expression. Genome Res (2010) 1.58
Genetic control of gene expression in whole blood and lymphoblastoid cell lines is largely independent. Genome Res (2011) 1.58
Expression quantitative trait loci detected in cell lines are often present in primary tissues. Hum Mol Genet (2009) 1.57
Interactions between glucocorticoid treatment and cis-regulatory polymorphisms contribute to cellular response phenotypes. PLoS Genet (2011) 1.49
The Brisbane Systems Genetics Study: genetical genomics meets complex trait genetics. PLoS One (2012) 1.49
Integrating genome-wide genetic variations and monocyte expression data reveals trans-regulated gene modules in humans. PLoS Genet (2011) 1.40
Extent, causes, and consequences of small RNA expression variation in human adipose tissue. PLoS Genet (2012) 1.28
The contribution of RNA decay quantitative trait loci to inter-individual variation in steady-state gene expression levels. PLoS Genet (2012) 1.25
Expression QTL analysis of top loci from GWAS meta-analysis highlights additional schizophrenia candidate genes. Eur J Hum Genet (2012) 1.14
MicroRNA expression in abdominal and gluteal adipose tissue is associated with mRNA expression levels and partly genetically driven. PLoS One (2011) 1.11
Exon-specific QTLs skew the inferred distribution of expression QTLs detected using gene expression array data. PLoS One (2012) 0.98
Cellular genomics for complex traits. Nat Rev Genet (2012) 0.97
Genetics and regulatory impact of alternative polyadenylation in human B-lymphoblastoid cells. PLoS Genet (2012) 0.96
Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS. Mol Syst Biol (2012) 0.93