Targeting histone deacetyalses in the treatment of B- and T-cell malignancies.

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Published in Invest New Drugs on December 04, 2010

Authors

Jasmine Zain1, Owen A O'Connor

Author Affiliations

1: NYU Clinical Cancer Center, 160 East 34th Street, New York, NY 10016, USA. Jasmine.zain@nyumc.org

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Translating the histone code. Science (2001) 56.77

Caspases: enemies within. Science (1998) 19.45

Epigenetics in cancer. N Engl J Med (2008) 17.36

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell (1997) 16.79

Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell (2001) 15.05

The Bcl2 family: regulators of the cellular life-or-death switch. Nat Rev Cancer (2002) 14.94

The Fas death factor. Science (1995) 13.81

WHO-EORTC classification for cutaneous lymphomas. Blood (2005) 12.14

Signal transduction by lymphocyte antigen receptors. Cell (1994) 10.63

International peripheral T-cell and natural killer/T-cell lymphoma study: pathology findings and clinical outcomes. J Clin Oncol (2008) 6.90

Duration of nuclear NF-kappaB action regulated by reversible acetylation. Science (2001) 6.79

HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor. Mol Cell (2005) 6.00

Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity. Biochem Biophys Res Commun (1999) 5.83

Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation. Proc Natl Acad Sci U S A (2000) 5.53

Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression. EMBO J (2002) 5.33

Stat3 dimerization regulated by reversible acetylation of a single lysine residue. Science (2005) 5.31

Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL). Blood (2006) 4.92

Phase I trial of the histone deacetylase inhibitor, depsipeptide (FR901228, NSC 630176), in patients with refractory neoplasms. Clin Cancer Res (2002) 4.90

The expression of a small fraction of cellular genes is changed in response to histone hyperacetylation. Gene Expr (1996) 4.62

Phase IIb multicenter trial of vorinostat in patients with persistent, progressive, or treatment refractory cutaneous T-cell lymphoma. J Clin Oncol (2007) 4.61

Histone deacetylase inhibitors in cancer therapy. J Clin Oncol (2009) 4.58

Phase I clinical trial of histone deacetylase inhibitor: suberoylanilide hydroxamic acid administered intravenously. Clin Cancer Res (2003) 4.55

Apoptotic and autophagic cell death induced by histone deacetylase inhibitors. Proc Natl Acad Sci U S A (2004) 4.20

Regulation of E2F1 activity by acetylation. EMBO J (2000) 4.18

Histone deacetylase (HDAC) inhibitor activation of p21WAF1 involves changes in promoter-associated proteins, including HDAC1. Proc Natl Acad Sci U S A (2004) 3.86

The nucleosome: from genomic organization to genomic regulation. Cell (2004) 3.83

Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis. Mol Cell (2004) 3.73

Cardiotoxicity of histone deacetylase inhibitor depsipeptide in patients with metastatic neuroendocrine tumors. Clin Cancer Res (2006) 3.72

Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors. Proc Natl Acad Sci U S A (2005) 3.66

Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity. Nat Med (2007) 3.61

Gene expression profiling of multiple histone deacetylase (HDAC) inhibitors: defining a common gene set produced by HDAC inhibition in T24 and MDA carcinoma cell lines. Mol Cancer Ther (2003) 3.37

Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation. Cell (2002) 3.28

Association between CpG island methylation and microsatellite instability in colorectal cancer. Cancer Res (1997) 3.09

Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes. Nat Med (2001) 3.07

Acetylation inactivates the transcriptional repressor BCL6. Nat Genet (2002) 3.00

Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents. J Hematol Oncol (2010) 2.94

The role of cytokines in classical Hodgkin lymphoma. Blood (2002) 2.86

Two major Smad pathways in TGF-beta superfamily signalling. Genes Cells (2002) 2.85

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Bcl-XL is qualitatively different from and ten times more effective than Bcl-2 when expressed in a breast cancer cell line. BMC Cancer (2006) 1.33

Receptor protein-tyrosine phosphatase gamma is a candidate tumor suppressor gene at human chromosome region 3p21. Proc Natl Acad Sci U S A (1991) 1.32

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The modular nature of apoptotic signaling proteins. Cell Mol Life Sci (1999) 1.19

Romidepsin for the treatment of cutaneous T-cell lymphoma. Drugs Today (Barc) (2009) 1.19

Prognostic significance of the therapeutic targets histone deacetylase 1, 2, 6 and acetylated histone H4 in cutaneous T-cell lymphoma. Histopathology (2008) 1.18

Potential efficacy of the oral histone deacetylase inhibitor vorinostat in a phase I trial in follicular and mantle cell lymphoma. Cancer Sci (2009) 1.12

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