Published in Cell Adh Migr on March 01, 2011
A molecular evolution approach to study the roles of tropomyosin in fission yeast. PLoS One (2013) 0.94
Occupy tissue: the movement in cancer metastasis. Cell Adh Migr (2012) 0.83
The cytoskeleton and neurite initiation. Bioarchitecture (2014) 0.83
Direct observation of tropomyosin binding to actin filaments. Cytoskeleton (Hoboken) (2015) 0.81
Expression of actin-binding proteins and requirement for actin-depolymerizing factor in chick neural crest cells. Dev Dyn (2014) 0.78
Tropomyosin Tm5NM1 spatially restricts src kinase activity through perturbation of Rab11 vesicle trafficking. Mol Cell Biol (2014) 0.76
The final cut: cell polarity meets cytokinesis at the bud neck in S. cerevisiae. Cell Mol Life Sci (2016) 0.76
Vitamin D receptor regulates intestinal proteins involved in cell proliferation, migration and stress response. Lipids Health Dis (2014) 0.76
Scared stiff: Stabilizing the actin cytoskeleton to stop invading cancer cells in their tracks. Bioarchitecture (2011) 0.76
Modular transcriptional repertoire and MicroRNA target analyses characterize genomic dysregulation in the thymus of Down syndrome infants. Oncotarget (2016) 0.75
Identification of a Gene Encoding Slow Skeletal Muscle Troponin T as a Novel Marker for Immortalization of Retinal Pigment Epithelial Cells. Sci Rep (2017) 0.75
The regulation of rabbit skeletal muscle contraction. I. Biochemical studies of the interaction of the tropomyosin-troponin complex with actin and the proteolytic fragments of myosin. J Biol Chem (1971) 35.39
Tumour-cell invasion and migration: diversity and escape mechanisms. Nat Rev Cancer (2003) 13.01
Two distinct actin networks drive the protrusion of migrating cells. Science (2004) 7.69
Tropomyosin: a new asymmetric protein component of the muscle fibril. Biochem J (1948) 6.86
Rac activation and inactivation control plasticity of tumor cell movement. Cell (2008) 6.01
Plasticity of cell migration: a multiscale tuning model. J Cell Biol (2009) 5.82
Proteins of the ADF/cofilin family: essential regulators of actin dynamics. Annu Rev Cell Dev Biol (1999) 5.76
Regulation of the interaction between actin and myosin subfragment 1: evidence for three states of the thin filament. Biophys J (1993) 5.66
Stress fibers are generated by two distinct actin assembly mechanisms in motile cells. J Cell Biol (2006) 5.54
One-dimensional topography underlies three-dimensional fibrillar cell migration. J Cell Biol (2009) 5.07
Patterns of organization of actin and myosin in normal and transformed cultured cells. Proc Natl Acad Sci U S A (1975) 4.86
Changing patterns of actin localization during cell division. Proc Natl Acad Sci U S A (1975) 3.07
Cell migration without a lamellipodium: translation of actin dynamics into cell movement mediated by tropomyosin. J Cell Biol (2005) 2.89
Motor domain-dependent localization of myo1b (myr-1). Curr Biol (2001) 2.88
Characterization of TPM1 disrupted yeast cells indicates an involvement of tropomyosin in directed vesicular transport. J Cell Biol (1992) 2.76
Tropomyosin-based regulation of the actin cytoskeleton in time and space. Physiol Rev (2008) 2.73
Tropomyosin binding to F-actin protects the F-actin from disassembly by brain actin-depolymerizing factor (ADF). Cell Motil (1982) 2.38
Tropomyosin inhibits ADF/cofilin-dependent actin filament dynamics. J Cell Biol (2002) 2.15
RhoB and actin polymerization coordinate Src activation with endosome-mediated delivery to the membrane. Dev Cell (2004) 2.13
Spatial regulation of actin dynamics: a tropomyosin-free, actin-rich compartment at the leading edge. J Cell Sci (2002) 2.11
Inhibition of the Arp2/3 complex-nucleated actin polymerization and branch formation by tropomyosin. Curr Biol (2001) 2.09
Electron tomography reveals unbranched networks of actin filaments in lamellipodia. Nat Cell Biol (2010) 2.02
Suppression of tropomyosin synthesis, a common biochemical feature of oncogenesis by structurally diverse retroviral oncogenes. Mol Cell Biol (1985) 1.85
Expression of transduced tropomyosin 1 cDNA suppresses neoplastic growth of cells transformed by the ras oncogene. Proc Natl Acad Sci U S A (1993) 1.81
Tropomyosin is essential in yeast, yet the TPM1 and TPM2 products perform distinct functions. J Cell Biol (1995) 1.73
Differential modulation of actin-severing activity of gelsolin by multiple isoforms of cultured rat cell tropomyosin. Potentiation of protective ability of tropomyosins by 83-kDa nonmuscle caldesmon. J Biol Chem (1989) 1.65
A muscle-type tropomyosin in human fibroblasts: evidence for expression by an alternative RNA splicing mechanism. Proc Natl Acad Sci U S A (1985) 1.59
Extranuclear apoptosis. The role of the cytoplasm in the execution phase. J Cell Biol (1999) 1.57
Specification of actin filament function and molecular composition by tropomyosin isoforms. Mol Biol Cell (2003) 1.51
Sequence repeats in alpha-tropomyosin. J Mol Biol (1975) 1.46
Amino-acid sequence of rabbit skeletal tropomyosin and its coiled-coil structure. Proc Natl Acad Sci U S A (1972) 1.42
Fimbrin and tropomyosin competition regulates endocytosis and cytokinesis kinetics in fission yeast. Curr Biol (2010) 1.37
Molecular and physiological effects of overexpressing striated muscle beta-tropomyosin in the adult murine heart. J Biol Chem (1995) 1.34
The relationship between curvature, flexibility and persistence length in the tropomyosin coiled-coil. J Struct Biol (2010) 1.27
Differential regulation of skeletal muscle myosin-II and brush border myosin-I enzymology and mechanochemistry by bacterially produced tropomyosin isoforms. Cell Motil Cytoskeleton (1994) 1.27
Tropomyosin isoform expression regulates the transition of adhesions to determine cell speed and direction. Mol Cell Biol (2009) 1.26
Differential localization of tropomyosin isoforms in cultured nonmuscle cells. J Cell Biol (1988) 1.24
Tropomyosin and myosin-II cellular levels promote actomyosin ring assembly in fission yeast. Mol Biol Cell (2010) 1.22
Differential regulation of unconventional fission yeast myosins via the actin track. Curr Biol (2010) 1.21
Loss of expression of tropomyosin-1, a novel class II tumor suppressor that induces anoikis, in primary breast tumors. Oncogene (2003) 1.20
The polymerization of proteins; adenosine triphosphate and the polymerization of actin. J Gen Physiol (1950) 1.19
Tissue-specific tropomyosin isoform composition. J Histochem Cytochem (2005) 1.17
Tropomodulin binds two tropomyosins: a novel model for actin filament capping. Biochemistry (2006) 1.16
Tropomyosin distinguishes between the two actin-binding sites of villin and affects actin-binding properties of other brush border proteins. J Cell Biol (1987) 1.15
Structure and tropomyosin binding properties of the N-terminal capping domain of tropomodulin 1. Biophys J (2004) 1.12
Regulation of actin binding and actin bundling activities of fascin by caldesmon coupled with tropomyosin. J Biol Chem (1998) 1.10
Annealing of gelsolin-severed actin fragments by tropomyosin in the presence of Ca2+. Potentiation of the annealing process by caldesmon. J Biol Chem (1989) 1.10
Resensitization of breast cancer cells to anoikis by tropomyosin-1: role of Rho kinase-dependent cytoskeleton and adhesion. Oncogene (2005) 1.09
Suppression of src-induced transformed phenotype by expression of tropomyosin-1. Oncogene (1999) 1.05
Specificity of dimer formation in tropomyosins: influence of alternatively spliced exons on homodimer and heterodimer assembly. Proc Natl Acad Sci U S A (1995) 1.05
Suppression of the transformed phenotype of breast cancer by tropomyosin-1. Exp Cell Res (2002) 1.01
Silencing of the Tropomyosin-1 gene by DNA methylation alters tumor suppressor function of TGF-beta. Oncogene (2005) 1.01
Human fibroblast tropomyosin isoforms: characterization of cDNA clones and analysis of tropomyosin isoform expression in human tissues and in normal and transformed cells. Cell Motil Cytoskeleton (1993) 0.99
The influence of microinjected phalloidin on locomotion, protoplasmic streaming and cytoplasmic organization in Amoeba proteus and Physarum polycephalum. Cytobiologie (1978) 0.98
Organization of the hTMnm gene. Implications for the evolution of muscle and non-muscle tropomyosins. J Mol Biol (1988) 0.96
The actin-associating protein Tm5NM1 blocks mesenchymal motility without transition to amoeboid motility. Oncogene (2010) 0.96
The coordination between actin filaments and adhesion in mesenchymal migration. Cell Adh Migr (2009) 0.95
Specialisation of the tropomyosin composition of actin filaments provides new potential targets for chemotherapy. Curr Cancer Drug Targets (2006) 0.95
Tropomyosin isoform modulation of focal adhesion structure and cell migration. Cell Adh Migr (2010) 0.95
Gamma tropomyosin gene products are required for embryonic development. Mol Cell Biol (2004) 0.93
Opposing roles of the extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascades in Ras-mediated downregulation of tropomyosin. Mol Cell Biol (2002) 0.90
Probing the role of nonmuscle tropomyosin isoforms in intracellular granule movement by microinjection of monoclonal antibodies. J Cell Biol (1989) 0.90
Low molecular weight rat fibroblast tropomyosin 5 (TM-5): cDNA cloning, actin-binding, localization, and coiled-coil interactions. Cell Motil Cytoskeleton (1996) 0.90
Tropomyosin isoforms define distinct microfilament populations with different drug susceptibility. Eur J Cell Biol (2008) 0.90
Alternatively spliced N-terminal exons in tropomyosin isoforms do not act as autonomous targeting signals. J Struct Biol (2009) 0.90
How tropomyosin regulates lamellipodial actin-based motility: a combined biochemical and reconstituted motility approach. EMBO J (2009) 0.89
Decreased expression of a single tropomyosin isoform, TM5/TM30nm, results in reduction in motility of highly metastatic B16-F10 mouse melanoma cells. Biochem Biophys Res Commun (1996) 0.89
Live imaging of glioblastoma cells in brain tissue shows requirement of actin bundles for migration. Neuron Glia Biol (2006) 0.87
Tropomyosin isoform 3 promotes the formation of filopodia by regulating the recruitment of actin-binding proteins to actin filaments. Exp Cell Res (2010) 0.87
Evolution of tropomyosin functional domains: differential splicing and genomic constraints. J Mol Evol (1988) 0.85
Tropomyosins are present in lamellipodia of motile cells. Eur J Cell Biol (2006) 0.82
Capping complex formation at the slow-growing end of the actin filament. Biochemistry (Mosc) (2008) 0.81
Transformation-related expression of a low-molecular-mass tropomyosin isoform TM5/TM30nm in transformed rat fibroblastic cell lines. J Cancer Res Clin Oncol (1997) 0.78
Functional analysis of the actin-binding protein, tropomyosin 1, in neuroblastoma. Br J Cancer (2003) 0.78
Periodicity of alpha-helical potential in tropomyosin sequence correlates with alternating actin binding sites. J Mol Biol (1980) 0.76
Tumor necrosis factor-alpha-induced secretion of RANTES and interleukin-6 from human airway smooth muscle cells: modulation by glucocorticoids and beta-agonists. Am J Respir Cell Mol Biol (2002) 1.37
Dissection of HEF1-dependent functions in motility and transcriptional regulation. J Cell Sci (2002) 1.29
Tropomyosin isoform expression regulates the transition of adhesions to determine cell speed and direction. Mol Cell Biol (2009) 1.26
The GDP exchange factor AND-34 is expressed in B cells, associates with HEF1, and activates Cdc42. J Immunol (2003) 1.06
γ-Actin regulates cell migration and modulates the ROCK signaling pathway. FASEB J (2011) 1.05
Altered progesterone receptor isoform expression remodels progestin responsiveness of breast cancer cells. Mol Endocrinol (2005) 1.04
Tropomyosin isoform modulation of focal adhesion structure and cell migration. Cell Adh Migr (2010) 0.95
Divergent regulation of the sarcomere and the cytoskeleton. J Biol Chem (2007) 0.95
Specialisation of the tropomyosin composition of actin filaments provides new potential targets for chemotherapy. Curr Cancer Drug Targets (2006) 0.95
NEDD9 stabilizes focal adhesions, increases binding to the extra-cellular matrix and differentially effects 2D versus 3D cell migration. PLoS One (2012) 0.93
PP2A phosphatase suppresses function of the mesenchymal invasion regulator NEDD9. Biochim Biophys Acta (2011) 0.91
Mesenchymal migration as a therapeutic target in glioblastoma. J Oncol (2010) 0.89
The Cas family docking protein, HEF1, promotes the formation of neurite-like membrane extensions. Biochim Biophys Acta (2005) 0.89
Structural insights into the association between BCAR3 and Cas family members, an atypical complex implicated in anti-oestrogen resistance. J Mol Biol (2008) 0.88
Regulation of focal adhesions by flightless i involves inhibition of paxillin phosphorylation via a Rac1-dependent pathway. J Invest Dermatol (2011) 0.85
Occupy tissue: the movement in cancer metastasis. Cell Adh Migr (2012) 0.83
NEDD9 regulates 3D migratory activity independent of the Rac1 morphology switch in glioma and neuroblastoma. Mol Cancer Res (2013) 0.80
Estradiol stabilizes the 105-kDa phospho-form of the adhesion docking protein NEDD9 and suppresses NEDD9-dependent cell spreading in breast cancer cells. Biochim Biophys Acta (2010) 0.80
Tyrosine Y189 in the substrate domain of the adhesion docking protein NEDD9 is conserved with p130Cas Y253 and regulates NEDD9-mediated migration and focal adhesion dynamics. PLoS One (2013) 0.79
Tropomyosin regulates cell migration during skin wound healing. J Invest Dermatol (2013) 0.78
Insights into adhesion biology using single-molecule localization microscopy. Chemphyschem (2014) 0.77
Role of dynamin in elongated cell migration in a 3D matrix. Biochim Biophys Acta (2014) 0.76
5 PicoNewtons - The Difference Between Osteogenic and Adipogenic Fate Choice in Human Mesenchymal Stem Cells. ACS Nano (2019) 0.75
Cell adhesion signaling and its impact on tumorigenesis. J Oncol (2011) 0.75