Published in Protein Cell on August 01, 2010
Regulation of neuronal cell death by c-Abl-Hippo/MST2 signaling pathway. PLoS One (2012) 0.87
Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene. Cancer Cell (2009) 7.39
A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span. Cell (2006) 5.36
Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression. Proc Natl Acad Sci U S A (2010) 4.17
Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase. Cell (2003) 4.13
Fat cadherin modulates organ size in Drosophila via the Salvador/Warts/Hippo signaling pathway. Curr Biol (2006) 3.72
Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded. Curr Biol (2010) 3.08
Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms. Curr Biol (2010) 2.97
The FERM-domain protein Expanded regulates Hippo pathway activity via direct interactions with the transcriptional activator Yorkie. Dev Cell (2009) 2.53
The WW domain protein Kibra acts upstream of Hippo in Drosophila. Dev Cell (2010) 2.34
Sterile 20 kinase phosphorylates histone H2B at serine 10 during hydrogen peroxide-induced apoptosis in S. cerevisiae. Cell (2005) 2.15
The Drosophila tumor suppressors Expanded and Merlin differentially regulate cell cycle exit, apoptosis, and Wingless signaling. Dev Biol (2006) 1.85
The pro-apoptotic kinase Mst1 and its caspase cleavage products are direct inhibitors of Akt1. EMBO J (2007) 1.69
Cloning and characterization of a member of the MST subfamily of Ste20-like kinases. Gene (1995) 1.63
The Nore1B/Mst1 complex restrains antigen receptor-induced proliferation of naïve T cells. Proc Natl Acad Sci U S A (2008) 1.61
Crucial role for Mst1 and Mst2 kinases in early embryonic development of the mouse. Mol Cell Biol (2009) 1.58
Mst1 controls lymphocyte trafficking and interstitial motility within lymph nodes. EMBO J (2009) 1.58
Newly identified stress-responsive protein kinases, Krs-1 and Krs-2. Proc Natl Acad Sci U S A (1996) 1.54
Mst1 is an interacting protein that mediates PHLPPs' induced apoptosis. Mol Cell (2010) 1.40
A cell-intrinsic role for Mst1 in regulating thymocyte egress. J Immunol (2009) 1.35
Biochemical analysis of MST1 kinase: elucidation of a C-terminal regulatory region. Biochemistry (2008) 1.14
Retracted Phosphoinositide 3-kinase/Akt inhibits MST1-mediated pro-apoptotic signaling through phosphorylation of threonine 120. J Biol Chem (2009) 1.12
Caspase-mediated activation of a 36-kDa myelin basic protein kinase during anticancer drug-induced apoptosis. Cancer Res (1998) 1.08
A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span. Cell (2006) 5.36
A calcium-regulated MEF2 sumoylation switch controls postsynaptic differentiation. Science (2006) 4.42
Cell-intrinsic regulation of axonal morphogenesis by the Cdh1-APC target SnoN. Neuron (2006) 1.98
TGFbeta-Smad2 signaling regulates the Cdh1-APC/SnoN pathway of axonal morphogenesis. J Neurosci (2008) 1.42
Advances of AKT pathway in human oncogenesis and as a target for anti-cancer drug discovery. Curr Cancer Drug Targets (2008) 1.33
c-Jun N-terminal kinase enhances MST1-mediated pro-apoptotic signaling through phosphorylation at serine 82. J Biol Chem (2009) 1.12
Insulin-like growth factor 1 receptor enhances invasion and induces resistance to apoptosis of colon cancer cells through the Akt/Bcl-x(L) pathway. Cancer Res (2003) 1.12
Lysine methylation of FOXO3 regulates oxidative stress-induced neuronal cell death. EMBO Rep (2012) 1.10
PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53. Nat Struct Mol Biol (2012) 1.09
Cell protective mechanism of valproic acid in lethal hemorrhagic shock. Surgery (2008) 1.09
YAP/TEAD-mediated transcription controls cellular senescence. Cancer Res (2013) 1.06
The c-Abl-MST1 signaling pathway mediates oxidative stress-induced neuronal cell death. J Neurosci (2011) 1.03
PP1A-mediated dephosphorylation positively regulates YAP2 activity. PLoS One (2011) 1.01
Ezh2 regulates adult hippocampal neurogenesis and memory. J Neurosci (2014) 0.99
Prevention of hypoxia-induced neuronal apoptosis through histone deacetylase inhibition. J Trauma (2008) 0.98
MST1 promotes apoptosis through regulating Sirt1-dependent p53 deacetylation. J Biol Chem (2011) 0.96
Mst1/Mst2 regulate development and function of regulatory T cells through modulation of Foxo1/Foxo3 stability in autoimmune disease. J Immunol (2014) 0.94
Brahma is essential for Drosophila intestinal stem cell proliferation and regulated by Hippo signaling. Elife (2013) 0.94
Methylation-mediated regulation of E2F1 in DNA damage-induced cell death. J Recept Signal Transduct Res (2011) 0.92
The tumor suppressor role of Src homology phosphotyrosine phosphatase 2 in hepatocellular carcinoma. J Cancer Res Clin Oncol (2012) 0.90
MST1, a key player, in enhancing fast skeletal muscle atrophy. BMC Biol (2013) 0.90
Regulation of neuronal cell death by c-Abl-Hippo/MST2 signaling pathway. PLoS One (2012) 0.87
Post-translational regulation of FOXO. Acta Biochim Biophys Sin (Shanghai) (2012) 0.85
Mitochondrial calcium uniporter protein MCU is involved in oxidative stress-induced cell death. Protein Cell (2015) 0.84
CAMKII and calcineurin regulate the lifespan of Caenorhabditis elegans through the FOXO transcription factor DAF-16. Elife (2013) 0.84
DJ-1 promotes the proteasomal degradation of Fis1: implications of DJ-1 in neuronal protection. Biochem J (2012) 0.81
The alteration of Hippo/YAP signaling in the development of hypertrophic cardiomyopathy. Basic Res Cardiol (2014) 0.80
Ca(2+) release induced by cADP-ribose is mediated by FKBP12.6 proteins in mouse bladder smooth muscle. Cell Calcium (2010) 0.79
Endoplasmic reticulum stress activates telomerase. Aging Cell (2013) 0.78
Interleukin-22 protects rat PC12 pheochromocytoma cells from serum deprivation-induced cell death. Mol Cell Biochem (2012) 0.78
Generation of Calhm1 knockout mouse and characterization of calhm1 gene expression. Protein Cell (2012) 0.78
Phosphoinositide 3-kinase/Akt inhibits MST1-mediated pro-apoptotic signaling through phosphorylation of threonine 120. J Biol Chem (2016) 0.75