Published in Dev Dyn on January 18, 2011
Self-renewing endodermal progenitor lines generated from human pluripotent stem cells. Cell Stem Cell (2012) 1.94
Bending gradients: how the intestinal stem cell gets its home. Cell (2015) 1.75
Generating human intestinal tissue from pluripotent stem cells in vitro. Nat Protoc (2011) 1.65
Intestinal development and differentiation. Exp Cell Res (2011) 1.44
Transplantation of expanded fetal intestinal progenitors contributes to colon regeneration after injury. Cell Stem Cell (2013) 1.39
Quiescent gastric stem cells maintain the adult Drosophila stomach. Proc Natl Acad Sci U S A (2011) 1.20
How to make an intestine. Development (2014) 1.10
A xenogeneic-free system generating functional human gut organoids from pluripotent stem cells. JCI Insight (2017) 1.07
Intestinal mucosal atrophy and adaptation. World J Gastroenterol (2012) 1.06
E-cadherin is required for intestinal morphogenesis in the mouse. Dev Biol (2012) 1.04
GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol (2014) 1.03
The role of gut adaptation in the potent effects of multiple bariatric surgeries on obesity and diabetes. Cell Metab (2015) 0.97
Convective tissue movements play a major role in avian endocardial morphogenesis. Dev Biol (2012) 0.93
Comprehensive timeline of mesodermal development in the quail small intestine. Dev Dyn (2012) 0.90
There is more than one way to turn a spherical cellular monolayer inside out: type B embryo inversion in Volvox globator. BMC Biol (2011) 0.90
Transcriptional networks in liver and intestinal development. Cold Spring Harb Perspect Biol (2012) 0.89
Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium. Dev Biol (2012) 0.88
Generating human intestinal tissues from pluripotent stem cells to study development and disease. EMBO J (2015) 0.88
Generating intestinal tissue from stem cells: potential for research and therapy. Regen Med (2011) 0.86
Mst1 and Mst2 kinases: regulations and diseases. Cell Biosci (2013) 0.85
Comparative evaluation of the genomes of three common Drosophila-associated bacteria. Biol Open (2016) 0.84
Role of GATA factors in development, differentiation, and homeostasis of the small intestinal epithelium. Am J Physiol Gastrointest Liver Physiol (2014) 0.83
A gutsy task: generating intestinal tissue from human pluripotent stem cells. Dig Dis Sci (2013) 0.83
Forkhead box F2 regulation of platelet-derived growth factor and myocardin/serum response factor signaling is essential for intestinal development. J Biol Chem (2015) 0.82
Building additional complexity to in vitro-derived intestinal tissues. Stem Cell Res Ther (2013) 0.81
ADAM Proteases and Gastrointestinal Function. Annu Rev Physiol (2015) 0.81
Loss of ascl1a prevents secretory cell differentiation within the zebrafish intestinal epithelium resulting in a loss of distal intestinal motility. Dev Biol (2013) 0.77
Generation of intestinal surface: an absorbing tale. Development (2016) 0.77
Roundabout is required in the visceral mesoderm for proper microvillus length in the hindgut epithelium. Dev Dyn (2012) 0.76
A YY1-dependent increase in aerobic metabolism is indispensable for intestinal organogenesis. Development (2016) 0.75
Analysis of duodenojejunal flexure formation in mice: implications for understanding the genetic basis for gastrointestinal morphology in mammals. J Anat (2013) 0.75
Quantification of spatiotemporal patterns of Ras isoform expression during development. Sci Rep (2017) 0.75
Distinct shape-shifting regimes of bowl-shaped cell sheets - embryonic inversion in the multicellular green alga Pleodorina. BMC Dev Biol (2016) 0.75
Control of stomach smooth muscle development and intestinal rotation by transcription factor BARX1. Dev Biol (2015) 0.75
Undervalued criteria in the evaluation of multimodal trials for upper GI cancers. Cancer Invest (2014) 0.75
Discovery of midgut genes for the RNA interference control of corn rootworm. Sci Rep (2016) 0.75
GATA4 Is Sufficient to Establish Jejunal Versus Ileal Identity in the Small Intestine. Cell Mol Gastroenterol Hepatol (2017) 0.75
Intestinal stem cell transplantation. J Gastroenterol (2016) 0.75
Role of ADAM10 in Intestinal Crypt Homeostasis and Tumorigenesis. Biochim Biophys Acta (2017) 0.75
Homeobox genes and axial patterning. Cell (1992) 12.03
Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells. Nature (2005) 11.49
Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat Biotechnol (2006) 10.95
Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo. Nat Biotechnol (2008) 10.60
Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4. Nat Genet (1998) 10.51
Efficient differentiation of human embryonic stem cells to definitive endoderm. Nat Biotechnol (2005) 9.58
Hox genes in vertebrate development. Cell (1994) 9.27
Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB. Cell (2002) 8.08
Control of endodermal endocrine development by Hes-1. Nat Genet (2000) 7.71
Coexistence of quiescent and active adult stem cells in mammals. Science (2010) 7.54
BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling. Nat Genet (2004) 7.37
Stem cells, self-renewal, and differentiation in the intestinal epithelium. Annu Rev Physiol (2009) 7.29
Requirement of Math1 for secretory cell lineage commitment in the mouse intestine. Science (2001) 7.17
Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype. Science (1995) 6.58
Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis. Nat Genet (2001) 6.36
An LDL-receptor-related protein mediates Wnt signalling in mice. Nature (2000) 6.34
Canonical Wnt signals are essential for homeostasis of the intestinal epithelium. Genes Dev (2003) 6.27
The adult Drosophila posterior midgut is maintained by pluripotent stem cells. Nature (2005) 6.20
Notch signals control the fate of immature progenitor cells in the intestine. Nature (2005) 6.13
Evidence that stem cells reside in the adult Drosophila midgut epithelium. Nature (2005) 5.86
A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo. Development (1999) 5.85
Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro. Nature (2010) 5.81
Strain-dependent epithelial defects in mice lacking the EGF receptor. Science (1995) 5.22
The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon. Development (2002) 5.09
Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1. Proc Natl Acad Sci U S A (2003) 4.76
Development of definitive endoderm from embryonic stem cells in culture. Development (2004) 4.61
Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor. Nature (1995) 4.56
Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium. J Cell Biol (2007) 4.52
De novo crypt formation and juvenile polyposis on BMP inhibition in mouse intestine. Science (2004) 4.39
Wnt signalling induces maturation of Paneth cells in intestinal crypts. Nat Cell Biol (2005) 4.34
The intestinal stem cell. Genes Dev (2008) 4.21
SOX9 is required for the differentiation of paneth cells in the intestinal epithelium. Gastroenterology (2007) 4.17
Depletion of definitive gut endoderm in Sox17-null mutant mice. Development (2002) 4.13
Expression pattern of Wnt signaling components in the adult intestine. Gastroenterology (2005) 4.09
Differentiation and transplantation of human embryonic stem cell-derived hepatocytes. Gastroenterology (2008) 3.99
Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation. Toxicol Sci (2004) 3.85
Regulatory phases of early liver development: paradigms of organogenesis. Nat Rev Genet (2002) 3.79
Wnt-3a regulates somite and tailbud formation in the mouse embryo. Genes Dev (1994) 3.77
Hedgehog signals regulate multiple aspects of gastrointestinal development. Development (2000) 3.77
Epimorphin: a mesenchymal protein essential for epithelial morphogenesis. Cell (1992) 3.63
Investigating stem cells in human colon by using methylation patterns. Proc Natl Acad Sci U S A (2001) 3.56
Nodal signaling: developmental roles and regulation. Development (2007) 3.44
Generation of pluripotent stem cells from patients with type 1 diabetes. Proc Natl Acad Sci U S A (2009) 3.43
Inducible Cre-mediated control of gene expression in the murine gastrointestinal tract: effect of loss of beta-catenin. Gastroenterology (2004) 3.39
Ezrin is essential for epithelial organization and villus morphogenesis in the developing intestine. Dev Cell (2004) 3.33
Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium. EMBO J (2002) 3.30
Directed differentiation of human embryonic stem cells into functional hepatic cells. Hepatology (2007) 3.29
Graded changes in dose of a Xenopus activin A homologue elicit stepwise transitions in embryonic cell fate. Nature (1990) 3.27
Blastocyst lineage formation, early embryonic asymmetries and axis patterning in the mouse. Development (2009) 3.25
Clonal analysis of epiblast fate during germ layer formation in the mouse embryo. Development (1991) 3.11
The endoderm of the mouse embryo arises by dynamic widespread intercalation of embryonic and extraembryonic lineages. Dev Cell (2008) 3.08
Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm. Genes Dev (2001) 3.04
Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2. EMBO Rep (2008) 3.03
Characterization of mesendoderm: a diverging point of the definitive endoderm and mesoderm in embryonic stem cell differentiation culture. Development (2005) 2.98
Development of the pattern of cell renewal in the crypt-villus unit of chimaeric mouse small intestine. Development (1988) 2.97
Gene function in mouse embryogenesis: get set for gastrulation. Nat Rev Genet (2007) 2.95
Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev (2005) 2.94
A bipotential precursor population for pancreas and liver within the embryonic endoderm. Development (2001) 2.85
Rapid loss of intestinal crypts upon conditional deletion of the Wnt/Tcf-4 target gene c-Myc. Mol Cell Biol (2006) 2.83
Intestine-specific ablation of mouse atonal homolog 1 (Math1) reveals a role in cellular homeostasis. Gastroenterology (2007) 2.79
Vertebrate endoderm development. Annu Rev Cell Dev Biol (1999) 2.73
Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells. Mol Cell Biol (2007) 2.67
Vertebrate endoderm development and organ formation. Annu Rev Cell Dev Biol (2009) 2.67
Nodal signalling in the epiblast patterns the early mouse embryo. Nature (2001) 2.65
Epithelial hedgehog signals pattern the intestinal crypt-villus axis. Development (2004) 2.62
Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2. Dev Cell (2009) 2.55
Delta-Notch signalling controls commitment to a secretory fate in the zebrafish intestine. Development (2005) 2.53
Repression of Wnt/beta-catenin signaling in the anterior endoderm is essential for liver and pancreas development. Development (2007) 2.50
Early mouse endoderm is patterned by soluble factors from adjacent germ layers. Development (2000) 2.49
Mitochondrial DNA mutations are established in human colonic stem cells, and mutated clones expand by crypt fission. Proc Natl Acad Sci U S A (2006) 2.42
Direct regulation of intestinal fate by Notch. Proc Natl Acad Sci U S A (2005) 2.41
The diverse functions of Krüppel-like factors 4 and 5 in epithelial biology and pathobiology. Bioessays (2007) 2.40
Postnatal development: coordination of feeding, digestion, and metabolism. Am J Physiol (1981) 2.38
Sox17 and beta-catenin cooperate to regulate the transcription of endodermal genes. Development (2004) 2.33
Minireview: Development and differentiation of gut endocrine cells. Endocrinology (2004) 2.32
Derivation of mouse intestinal crypts from single progenitor cells. Nature (1985) 2.31
Demonstration of somatic mutation and colonic crypt clonality by X-linked enzyme histochemistry. Nature (1988) 2.28
Sonic hedgehog is an endodermal signal inducing Bmp-4 and Hox genes during induction and regionalization of the chick hindgut. Development (1995) 2.25
Making worm guts: the gene regulatory network of the Caenorhabditis elegans endoderm. Dev Biol (2002) 2.24
Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures. Cell (1990) 2.22
The homeobox gene Hex is required in definitive endodermal tissues for normal forebrain, liver and thyroid formation. Development (2000) 2.22
Polyclonal origin of colonic adenomas in an XO/XY patient with FAP. Science (1996) 2.22
GATA transcription factors as potentiators of gut endoderm differentiation. Development (1998) 2.20
Nodal signalling in vertebrate development. Nature (2000) 2.20
Targeted mutagenesis of the transcription factor GATA-4 gene in mouse embryonic stem cells disrupts visceral endoderm differentiation in vitro. Development (1995) 2.19
Identification of a potent Xenopus mesoderm-inducing factor as a homologue of activin A. Nature (1990) 2.17
Positional cloning of heart and soul reveals multiple roles for PKC lambda in zebrafish organogenesis. Curr Biol (2001) 2.16
Nodal antagonists regulate formation of the anteroposterior axis of the mouse embryo. Nature (2004) 2.16
Disruption of the murine homeobox gene Cdx1 affects axial skeletal identities by altering the mesodermal expression domains of Hox genes. Cell (1995) 2.15
Sox17 regulates organ lineage segregation of ventral foregut progenitor cells. Dev Cell (2009) 2.14
Dynamic signaling network for the specification of embryonic pancreas and liver progenitors. Science (2009) 2.12
Cdx2 is essential for axial elongation in mouse development. Proc Natl Acad Sci U S A (2004) 2.08
Genetic dissection of nodal function in patterning the mouse embryo. Development (2001) 2.07
Bone morphogenetic protein signaling is essential for terminal differentiation of the intestinal secretory cell lineage. Gastroenterology (2007) 2.07
Nodal and BMP2/4 signaling organizes the oral-aboral axis of the sea urchin embryo. Dev Cell (2004) 2.07
The C. elegans intestine. WormBook (2007) 2.06
Gene dosage-dependent effects of the Hoxa-13 and Hoxd-13 mutations on morphogenesis of the terminal parts of the digestive and urogenital tracts. Development (1997) 2.05
Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon. Gastroenterology (2006) 2.04
Noggin, retinoids, and fibroblast growth factor regulate hepatic or pancreatic fate of human embryonic stem cells. Gastroenterology (2010) 2.03
Hedgehog signaling in development and homeostasis of the gastrointestinal tract. Physiol Rev (2007) 2.02
Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts. Nature (2010) 10.60
Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro. Nature (2010) 5.81
Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells. Mol Cell Biol (2007) 2.67
Distinct ATOH1 and Neurog3 requirements define tuft cells as a new secretory cell type in the intestinal epithelium. J Cell Biol (2011) 2.21
Facile isolation and the characterization of human retinal stem cells. Proc Natl Acad Sci U S A (2004) 2.18
Induction of intestinal stem cells by R-spondin 1 and Slit2 augments chemoradioprotection. Nature (2013) 1.91
Functional intestinal stem cells after Paneth cell ablation induced by the loss of transcription factor Math1 (Atoh1). Proc Natl Acad Sci U S A (2012) 1.83
Atonal homolog 1 is a tumor suppressor gene. PLoS Biol (2009) 1.76
Generating human intestinal tissue from pluripotent stem cells in vitro. Nat Protoc (2011) 1.65
SAM pointed domain ETS factor (SPDEF) regulates terminal differentiation and maturation of intestinal goblet cells. Exp Cell Res (2009) 1.64
Identification of epithelial gaps in human small and large intestine by confocal endomicroscopy. Gastroenterology (2007) 1.61
Intestinal adaptation after ileal interposition surgery increases bile acid recycling and protects against obesity-related comorbidities. Am J Physiol Gastrointest Liver Physiol (2010) 1.54
Atonal homolog 1 is required for growth and differentiation effects of notch/gamma-secretase inhibitors on normal and cancerous intestinal epithelial cells. Gastroenterology (2010) 1.52
Intestinal development and differentiation. Exp Cell Res (2011) 1.44
Complex interplay between β-catenin signalling and Notch effectors in intestinal tumorigenesis. Gut (2011) 1.33
Endothelial PAS domain protein 1 activates the inflammatory response in the intestinal epithelium to promote colitis in mice. Gastroenterology (2013) 1.30
Sox9 plays multiple roles in the lung epithelium during branching morphogenesis. Proc Natl Acad Sci U S A (2013) 1.29
Stem cell-derived human intestinal organoids as an infection model for rotaviruses. MBio (2012) 1.27
GATA factors regulate proliferation, differentiation, and gene expression in small intestine of mature mice. Gastroenterology (2011) 1.18
Notch in the intestine: regulation of homeostasis and pathogenesis. Annu Rev Physiol (2012) 1.15
A novel role of the hedgehog pathway in lens regeneration. Dev Biol (2004) 1.12
How to make an intestine. Development (2014) 1.10
Gfi1-cells and circuits: unraveling transcriptional networks of development and disease. Curr Opin Hematol (2010) 1.01
Identification of microRNAs and other small RNAs from the adult newt eye. Mol Vis (2006) 1.01
An ABCA4 genomic deletion in patients with Stargardt disease. Hum Mutat (2003) 0.99
Intestinal crypts reproducibly expand in culture. J Surg Res (2012) 0.96
Interleukin-13 (IL-13)/IL-13 receptor alpha1 (IL-13Ralpha1) signaling regulates intestinal epithelial cystic fibrosis transmembrane conductance regulator channel-dependent Cl- secretion. J Biol Chem (2011) 0.94
SPDEF functions as a colorectal tumor suppressor by inhibiting β-catenin activity. Gastroenterology (2013) 0.91
The use of murine-derived fundic organoids in studies of gastric physiology. J Physiol (2015) 0.90
Selenoprotein P influences colitis-induced tumorigenesis by mediating stemness and oxidative damage. J Clin Invest (2015) 0.87
NOTCH Signaling and ATOH1 in Colorectal Cancers. Curr Colorectal Cancer Rep (2011) 0.86
Intestinal stem cells remain viable after prolonged tissue storage. Cell Tissue Res (2013) 0.85
A gutsy task: generating intestinal tissue from human pluripotent stem cells. Dig Dis Sci (2013) 0.83
BMP signaling in the intestine: cross-talk is key. Gastroenterology (2007) 0.81
Insulin concentration modulates hepatic lipid accumulation in mice in part via transcriptional regulation of fatty acid transport proteins. PLoS One (2012) 0.79
Krüpple-like factor 5 is required for proper maintenance of adult intestinal crypt cellular proliferation. Dig Dis Sci (2014) 0.78
Cancer biology: a new RING to Wnt signaling. Curr Biol (2012) 0.78