Gata4 is essential for the maintenance of jejunal-ileal identities in the adult mouse small intestine.

PubWeight™: 1.71‹?› | Rank: Top 3%

🔗 View Article (PMC 1636804)

Published in Mol Cell Biol on August 28, 2006

Authors

Tjalling Bosse1, Christina M Piaseckyj, Ellen Burghard, John J Fialkovich, Satish Rajagopal, William T Pu, Stephen D Krasinski

Author Affiliations

1: GI/Cell Biology, EN 720, Children's Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA.

Articles citing this

Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut. Nat Med (2011) 3.06

Bile acid transporters. J Lipid Res (2009) 2.31

GATA Transcription Factors and Cancer. Genes Cancer (2010) 1.88

Lactose digestion and the evolutionary genetics of lactase persistence. Hum Genet (2008) 1.75

Spectrum of heart disease associated with murine and human GATA4 mutation. J Mol Cell Cardiol (2007) 1.71

Intestinal development and differentiation. Exp Cell Res (2011) 1.44

Vertebrate intestinal endoderm development. Dev Dyn (2011) 1.41

GATA4 is essential for jejunal function in mice. Gastroenterology (2008) 1.39

TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions. Proc Natl Acad Sci U S A (2010) 1.32

Transcription factors GATA-4 and GATA-6 in normal and neoplastic human gastrointestinal mucosa. BMC Gastroenterol (2008) 1.28

Nkx2.2 regulates cell fate choice in the enteroendocrine cell lineages of the intestine. Dev Biol (2007) 1.27

GATA factors regulate proliferation, differentiation, and gene expression in small intestine of mature mice. Gastroenterology (2011) 1.18

Role of the intestinal bile acid transporters in bile acid and drug disposition. Handb Exp Pharmacol (2011) 1.14

Mapping of HNF4alpha target genes in intestinal epithelial cells. BMC Gastroenterol (2009) 1.08

Combinatorial regulation of tissue specification by GATA and FOG factors. Development (2012) 1.06

Conditional ablation of Gata4 and Fog2 genes in mice reveals their distinct roles in mammalian sexual differentiation. Dev Biol (2011) 1.05

GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol (2014) 1.03

GATA4 mediates gene repression in the mature mouse small intestine through interactions with friend of GATA (FOG) cofactors. Dev Biol (2008) 1.02

Loss of GATA-6 and GATA-4 in granulosa cells blocks folliculogenesis, ovulation, and follicle stimulating hormone receptor expression leading to female infertility. Endocrinology (2012) 1.01

Conditional Gata4 deletion in mice induces bile acid absorption in the proximal small intestine. Gut (2010) 1.01

Cooperation between HNF-1alpha, Cdx2, and GATA-4 in initiating an enterocytic differentiation program in a normal human intestinal epithelial progenitor cell line. Am J Physiol Gastrointest Liver Physiol (2010) 0.97

Getting the mOST from OST: Role of organic solute transporter, OSTalpha-OSTbeta, in bile acid and steroid metabolism. Biochim Biophys Acta (2010) 0.97

Potent stimulation of fibroblast growth factor 19 expression in the human ileum by bile acids. Am J Physiol Gastrointest Liver Physiol (2013) 0.95

GATA6 is required for proliferation, migration, secretory cell maturation, and gene expression in the mature mouse colon. Mol Cell Biol (2012) 0.93

Direct transcriptional regulation of Gata4 during early endoderm specification is controlled by FoxA2 binding to an intronic enhancer. Dev Biol (2010) 0.93

An endoderm-specific transcriptional enhancer from the mouse Gata4 gene requires GATA and homeodomain protein-binding sites for function in vivo. Dev Dyn (2009) 0.92

Small intestinal stem cell identity is maintained with functional Paneth cells in heterotopically grafted epithelium onto the colon. Genes Dev (2014) 0.91

Boundaries, junctions and transitions in the gastrointestinal tract. Exp Cell Res (2011) 0.90

The transcription factor Atonal homolog 8 regulates Gata4 and Friend of Gata-2 during vertebrate development. J Biol Chem (2013) 0.88

Gut microbiota inhibit Asbt-dependent intestinal bile acid reabsorption via Gata4. J Hepatol (2015) 0.85

Transcription factors GATA4 and HNF4A control distinct aspects of intestinal homeostasis in conjunction with transcription factor CDX2. J Biol Chem (2014) 0.85

Regulation of mouse intestinal L cell progenitors proliferation by the glucagon family of peptides. Endocrinology (2012) 0.84

Zinc in gut-brain interaction in autism and neurological disorders. Neural Plast (2015) 0.83

A gutsy task: generating intestinal tissue from human pluripotent stem cells. Dig Dis Sci (2013) 0.83

Bacterial-dependent up-regulation of intestinal bile acid binding protein and transport is FXR-mediated following ileo-cecal resection. Surgery (2008) 0.83

Role of GATA factors in development, differentiation, and homeostasis of the small intestinal epithelium. Am J Physiol Gastrointest Liver Physiol (2014) 0.83

GATA4 represses an ileal program of gene expression in the proximal small intestine by inhibiting the acetylation of histone H3, lysine 27. Biochim Biophys Acta (2014) 0.83

Characterization of the developing small intestine in the absence of either GATA4 or GATA6. BMC Res Notes (2014) 0.82

PIAS1 is a GATA4 SUMO ligase that regulates GATA4-dependent intestinal promoters independent of SUMO ligase activity and GATA4 sumoylation. PLoS One (2012) 0.82

Epigenetic modulation of intestinal cholesterol transporter Niemann-Pick C1-like 1 (NPC1L1) gene expression by DNA methylation. J Biol Chem (2014) 0.81

Loss of intestinal GATA4 prevents diet-induced obesity and promotes insulin sensitivity in mice. Am J Physiol Endocrinol Metab (2010) 0.81

GATA4 regulates epithelial cell proliferation to control intestinal growth and development in mice. Cell Mol Gastroenterol Hepatol (2016) 0.80

Spdef deletion rescues the crypt cell proliferation defect in conditional Gata6 null mouse small intestine. BMC Mol Biol (2014) 0.79

mTOR disruption causes intestinal epithelial cell defects and intestinal atrophy postinjury in mice. FASEB J (2015) 0.79

DNA methylation restricts lineage-specific functions of transcription factor Gata4 during embryonic stem cell differentiation. PLoS Genet (2013) 0.79

Enhanced expression of transcription factor GATA-4 in inflammatory bowel disease and its possible regulation by TGF-beta1. J Clin Immunol (2009) 0.77

Intestinal GATA4 deficiency protects from diet-induced hepatic steatosis. J Hepatol (2012) 0.76

Gata4 is critical to maintain gut barrier function and mucosal integrity following epithelial injury. Sci Rep (2016) 0.75

Insights From the Crypt: Regionalization, Adaptation, and Renewal of the Intestinal Epithelium. Cell Mol Gastroenterol Hepatol (2017) 0.75

Id2 deletion attenuates Apc-deficient ileal tumor formation. Biol Open (2015) 0.75

Transcriptional heterogeneity in the lactase gene within cell-type is linked to the epigenome. Sci Rep (2017) 0.75

GATA4 Is Sufficient to Establish Jejunal Versus Ileal Identity in the Small Intestine. Cell Mol Gastroenterol Hepatol (2017) 0.75

The Contributions of Human Mini-Intestines to the Study of Intestinal Physiology and Pathophysiology. Annu Rev Physiol (2017) 0.75

Genomic dissection of conserved transcriptional regulation in intestinal epithelial cells. PLoS Biol (2017) 0.75

Articles cited by this

Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet (1999) 55.63

Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse. Dev Biol (2002) 13.87

Control of endodermal endocrine development by Hes-1. Nat Genet (2000) 7.71

Requirement of Math1 for secretory cell lineage commitment in the mouse intestine. Science (2001) 7.17

Tissue-specific and inducible Cre-mediated recombination in the gut epithelium. Genesis (2004) 6.83

Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis. Genes Dev (1997) 6.52

Canonical Wnt signals are essential for homeostasis of the intestinal epithelium. Genes Dev (2003) 6.27

GATA4 transcription factor is required for ventral morphogenesis and heart tube formation. Genes Dev (1997) 5.51

The zinc finger-containing transcription factors GATA-4, -5, and -6. Ubiquitously expressed regulators of tissue-specific gene expression. J Biol Chem (2000) 5.02

Cdx2 ectopic expression induces gastric intestinal metaplasia in transgenic mice. Gastroenterology (2002) 3.39

The GATA-factor elt-2 is essential for formation of the Caenorhabditis elegans intestine. Dev Biol (1998) 3.25

GATA4 is essential for formation of the proepicardium and regulates cardiogenesis. Proc Natl Acad Sci U S A (2004) 3.08

Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism. Nat Genet (2001) 2.73

GATA-1 forms distinct activating and repressive complexes in erythroid cells. EMBO J (2005) 2.56

Morphogenesis of the right ventricle requires myocardial expression of Gata4. J Clin Invest (2005) 2.50

A molecular aspect of hematopoiesis and endoderm development common to vertebrates and Drosophila. Development (1996) 2.42

Direct regulation of intestinal fate by Notch. Proc Natl Acad Sci U S A (2005) 2.41

Functional biology of intestinal goblet cells. Am J Physiol (1991) 2.37

Minireview: Development and differentiation of gut endocrine cells. Endocrinology (2004) 2.32

Experimental conversion of liver to pancreas. Curr Biol (2003) 2.24

Distinct functions are implicated for the GATA-4, -5, and -6 transcription factors in the regulation of intestine epithelial cell differentiation. Mol Cell Biol (1998) 2.17

The human and rodent intestinal fatty acid binding protein genes. A comparative analysis of their structure, expression, and linkage relationships. J Biol Chem (1987) 2.13

GATA4 is a dosage-sensitive regulator of cardiac morphogenesis. Dev Biol (2004) 2.13

Gata4 regulates the formation of multiple organs. Development (2005) 2.02

Gastrointestinal stem cells. II. Intestinal stem cells. Am J Physiol Gastrointest Liver Physiol (2005) 1.87

Molecular cloning of FOG-2: a modulator of transcription factor GATA-4 in cardiomyocytes. Proc Natl Acad Sci U S A (1999) 1.86

Live and let die in the intestinal epithelium. Curr Opin Cell Biol (2003) 1.85

Use of transgenic mice to map cis-acting elements in the liver fatty acid-binding protein gene (Fabpl) that regulate its cell lineage-specific, differentiation-dependent, and spatial patterns of expression in the gut epithelium and in the liver acinus. J Biol Chem (1993) 1.72

Hepatocyte nuclear factor-1 alpha, GATA-4, and caudal related homeodomain protein Cdx2 interact functionally to modulate intestinal gene transcription. Implication for the developmental regulation of the sucrase-isomaltase gene. J Biol Chem (2002) 1.68

Studies of intestinal stem cells using normal, chimeric, and transgenic mice. FASEB J (1992) 1.61

Liver receptor homologue-1 mediates species- and cell line-specific bile acid-dependent negative feedback regulation of the apical sodium-dependent bile acid transporter. J Biol Chem (2002) 1.60

Generation of mice harbouring a conditional loss-of-function allele of Gata6. BMC Dev Biol (2006) 1.35

The mouse ileal lipid-binding protein gene: a model for studying axial patterning during gut morphogenesis. J Cell Biol (1994) 1.29

The human sucrase-isomaltase gene directs complex patterns of gene expression in transgenic mice. Am J Physiol (1993) 1.23

Intestinal bile acid transport: biology, physiology, and pathophysiology. J Pediatr Gastroenterol Nutr (2001) 1.16

Adult-type hypolactasia and regulation of lactase expression. Biochim Biophys Acta (2005) 1.11

Differential activation of intestinal gene promoters: functional interactions between GATA-5 and HNF-1 alpha. Am J Physiol Gastrointest Liver Physiol (2001) 1.11

Complex regulation of the lactase-phlorizin hydrolase promoter by GATA-4. Am J Physiol Gastrointest Liver Physiol (2004) 1.08

The role of AP-1 in the transcriptional regulation of the rat apical sodium-dependent bile acid transporter. J Biol Chem (2001) 1.08

Epithelial lineages of the small intestine have unique patterns of GATA expression. J Mol Histol (2005) 1.08

Physical interaction between GATA-5 and hepatocyte nuclear factor-1alpha results in synergistic activation of the human lactase-phlorizin hydrolase promoter. J Biol Chem (2002) 1.05

GATA-4, GATA-5, and GATA-6 activate the rat liver fatty acid binding protein gene in concert with HNF-1alpha. Am J Physiol Gastrointest Liver Physiol (2004) 1.04

HNF-1 alpha and HNF-1 beta expression in mouse intestinal crypts. Am J Physiol (1993) 1.00

GATA family transcription factors activate lactase gene promoter in intestinal Caco-2 cells. Am J Physiol Gastrointest Liver Physiol (2001) 0.97

High-level activation by a duodenum-specific enhancer requires functional GATA binding sites. Am J Physiol Gastrointest Liver Physiol (2003) 0.93

Rat lactase-phlorizin hydrolase/human growth hormone transgene is expressed on small intestinal villi in transgenic mice. Gastroenterology (1997) 0.91

Hepatocyte nuclear factor-1alpha is required for expression but dispensable for histone acetylation of the lactase-phlorizin hydrolase gene in vivo. Am J Physiol Gastrointest Liver Physiol (2005) 0.89

Rapid induction of GATA transcription factors in developing mouse intestine following glucocorticoid administration. Am J Physiol Gastrointest Liver Physiol (2004) 0.84

Articles by these authors

Endothelial-to-mesenchymal transition contributes to cardiac fibrosis. Nat Med (2007) 9.51

Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart. Nature (2008) 7.03

Altered microRNA expression in human heart disease. Physiol Genomics (2007) 5.64

De novo cardiomyocytes from within the activated adult heart after injury. Nature (2011) 5.17

Adult cardiac-resident MSC-like stem cells with a proepicardial origin. Cell Stem Cell (2011) 3.56

Co-occupancy by multiple cardiac transcription factors identifies transcriptional enhancers active in heart. Proc Natl Acad Sci U S A (2011) 3.18

Adult mouse epicardium modulates myocardial injury by secreting paracrine factors. J Clin Invest (2011) 2.99

Morphogenesis of the right ventricle requires myocardial expression of Gata4. J Clin Invest (2005) 2.50

A multivariate approach for integrating genome-wide expression data and biological knowledge. Bioinformatics (2006) 2.42

Overexpression of HAX-1 protects cardiac myocytes from apoptosis through caspase-9 inhibition. Circ Res (2006) 2.27

MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes. Mol Cell Biol (2009) 2.18

YAP1, the nuclear target of Hippo signaling, stimulates heart growth through cardiomyocyte proliferation but not hypertrophy. Proc Natl Acad Sci U S A (2012) 2.13

Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction. Nat Biotechnol (2013) 2.11

Polycomb repressive complex 2 regulates normal development of the mouse heart. Circ Res (2011) 2.05

Septum transversum-derived mesothelium gives rise to hepatic stellate cells and perivascular mesenchymal cells in developing mouse liver. Hepatology (2011) 1.95

Development of heart valves requires Gata4 expression in endothelial-derived cells. Development (2006) 1.90

Reassessment of Isl1 and Nkx2-5 cardiac fate maps using a Gata4-based reporter of Cre activity. Dev Biol (2008) 1.88

Dilated cardiomyopathy resulting from high-level myocardial expression of Cre-recombinase. J Card Fail (2006) 1.79

Thymosin beta 4 treatment after myocardial infarction does not reprogram epicardial cells into cardiomyocytes. J Mol Cell Cardiol (2011) 1.77

Platelet-derived growth factor receptor beta signaling is required for efficient epicardial cell migration and development of two distinct coronary vascular smooth muscle cell populations. Circ Res (2008) 1.76

Gata4 is required for maintenance of postnatal cardiac function and protection from pressure overload-induced heart failure. Proc Natl Acad Sci U S A (2006) 1.73

Spectrum of heart disease associated with murine and human GATA4 mutation. J Mol Cell Cardiol (2007) 1.71

Hepatocyte nuclear factor-1 alpha, GATA-4, and caudal related homeodomain protein Cdx2 interact functionally to modulate intestinal gene transcription. Implication for the developmental regulation of the sucrase-isomaltase gene. J Biol Chem (2002) 1.68

PRC2 directly methylates GATA4 and represses its transcriptional activity. Genes Dev (2012) 1.66

Synergistic effects of the GATA-4-mediated miR-144/451 cluster in protection against simulated ischemia/reperfusion-induced cardiomyocyte death. J Mol Cell Cardiol (2010) 1.66

Perioperative factors associated with prolonged mechanical ventilation after complex congenital heart surgery. Pediatr Crit Care Med (2011) 1.64

Genetic fate mapping demonstrates contribution of epicardium-derived cells to the annulus fibrosis of the mammalian heart. Dev Biol (2009) 1.63

Endocardial and epicardial epithelial to mesenchymal transitions in heart development and disease. Circ Res (2012) 1.57

GATA4 is a direct transcriptional activator of cyclin D2 and Cdk4 and is required for cardiomyocyte proliferation in anterior heart field-derived myocardium. Mol Cell Biol (2008) 1.56

WT1 regulates epicardial epithelial to mesenchymal transition through β-catenin and retinoic acid signaling pathways. Dev Biol (2011) 1.53

CIP, a cardiac Isl1-interacting protein, represses cardiomyocyte hypertrophy. Circ Res (2012) 1.46

Nkx2-5- and Isl1-expressing cardiac progenitors contribute to proepicardium. Biochem Biophys Res Commun (2008) 1.40

A Tbx1-Six1/Eya1-Fgf8 genetic pathway controls mammalian cardiovascular and craniofacial morphogenesis. J Clin Invest (2011) 1.39

Impaired mesenchymal cell function in Gata4 mutant mice leads to diaphragmatic hernias and primary lung defects. Dev Biol (2006) 1.36

Blimp1 regulates the transition of neonatal to adult intestinal epithelium. Nat Commun (2011) 1.36

Dissecting spatio-temporal protein networks driving human heart development and related disorders. Mol Syst Biol (2010) 1.35

Fog2 is critical for cardiac function and maintenance of coronary vasculature in the adult mouse heart. J Clin Invest (2009) 1.32

Regulation of GATA4 transcriptional activity in cardiovascular development and disease. Curr Top Dev Biol (2012) 1.29

Transcription factor gata4 regulates cardiac BCL2 gene expression in vitro and in vivo. FASEB J (2006) 1.25

Serine 105 phosphorylation of transcription factor GATA4 is necessary for stress-induced cardiac hypertrophy in vivo. Proc Natl Acad Sci U S A (2011) 1.23

Heart failure-associated changes in RNA splicing of sarcomere genes. Circ Cardiovasc Genet (2010) 1.23

GATA factors regulate proliferation, differentiation, and gene expression in small intestine of mature mice. Gastroenterology (2011) 1.18

Developmental changes in ventricular diastolic function correlate with changes in ventricular myoarchitecture in normal mouse embryos. Circ Res (2003) 1.18

WT1 maintains adrenal-gonadal primordium identity and marks a population of AGP-like progenitors within the adrenal gland. Dev Cell (2013) 1.16

Equal modulation of endothelial cell function by four distinct tissue-specific mesenchymal stem cells. Angiogenesis (2012) 1.14

miR-155 inhibits expression of the MEF2A protein to repress skeletal muscle differentiation. J Biol Chem (2011) 1.13

Uncoupling protein 2 modulates cell viability in adult rat cardiomyocytes. Am J Physiol Heart Circ Physiol (2007) 1.11

CompleteMOTIFs: DNA motif discovery platform for transcription factor binding experiments. Bioinformatics (2010) 1.11

Interrogating translational efficiency and lineage-specific transcriptomes using ribosome affinity purification. Proc Natl Acad Sci U S A (2013) 1.09

Genetic and environmental risk factors in congenital heart disease functionally converge in protein networks driving heart development. Proc Natl Acad Sci U S A (2012) 1.08

Complex regulation of the lactase-phlorizin hydrolase promoter by GATA-4. Am J Physiol Gastrointest Liver Physiol (2004) 1.08

A simple method for deriving functional MSCs and applied for osteogenesis in 3D scaffolds. Sci Rep (2013) 1.07

More than a cover: epicardium as a novel source of cardiac progenitor cells. Regen Med (2008) 1.06

A dynamic H3K27ac signature identifies VEGFA-stimulated endothelial enhancers and requires EP300 activity. Genome Res (2013) 1.05

Physical interaction between GATA-5 and hepatocyte nuclear factor-1alpha results in synergistic activation of the human lactase-phlorizin hydrolase promoter. J Biol Chem (2002) 1.05

Congenital heart disease-causing Gata4 mutation displays functional deficits in vivo. PLoS Genet (2012) 1.03

Transcription factor genes Smad4 and Gata4 cooperatively regulate cardiac valve development. [corrected] Proc Natl Acad Sci U S A (2011) 1.02

GATA4 mediates gene repression in the mature mouse small intestine through interactions with friend of GATA (FOG) cofactors. Dev Biol (2008) 1.02

Genetic Cre-loxP assessment of epicardial cell fate using Wt1-driven Cre alleles. Circ Res (2012) 1.02

Inducible cardiomyocyte-specific gene disruption directed by the rat Tnnt2 promoter in the mouse. Genesis (2010) 1.02

Conditional Gata4 deletion in mice induces bile acid absorption in the proximal small intestine. Gut (2010) 1.01

Genome-wide location analysis by pull down of in vivo biotinylated transcription factors. Curr Protoc Mol Biol (2010) 1.00

Timing of myocardial trpm7 deletion during cardiogenesis variably disrupts adult ventricular function, conduction, and repolarization. Circulation (2013) 0.97

Gata4 and Hnf1alpha are partially required for the expression of specific intestinal genes during development. Am J Physiol Gastrointest Liver Physiol (2007) 0.96

Epicardial epithelial-to-mesenchymal transition in injured heart. J Cell Mol Med (2011) 0.95

Expression and function of microRNAs in heart disease. Curr Drug Targets (2010) 0.95

GATA6 is required for proliferation, migration, secretory cell maturation, and gene expression in the mature mouse colon. Mol Cell Biol (2012) 0.93

Myocardial regeneration: expanding the repertoire of thymosin β4 in the ischemic heart. Ann N Y Acad Sci (2012) 0.93

Transcription factor GATA4 is activated but not required for insulin-like growth factor 1 (IGF1)-induced cardiac hypertrophy. J Biol Chem (2012) 0.92

Control of differentiation-induced calbindin-D9k gene expression in Caco-2 cells by cdx-2 and HNF-1alpha. Am J Physiol Gastrointest Liver Physiol (2004) 0.90

Hepatocyte nuclear factor-1alpha is required for expression but dispensable for histone acetylation of the lactase-phlorizin hydrolase gene in vivo. Am J Physiol Gastrointest Liver Physiol (2005) 0.89

Endostatin lowers blood pressure via nitric oxide and prevents hypertension associated with VEGF inhibition. Proc Natl Acad Sci U S A (2012) 0.89

Structural characterization of the mouse Girk genes. Gene (2002) 0.88

Isolation and characterization of embryonic and adult epicardium and epicardium-derived cells. Methods Mol Biol (2012) 0.86

Peritruncal coronary endothelial cells contribute to proximal coronary artery stems and their aortic orifices in the mouse heart. PLoS One (2013) 0.85

Cardiac expression of ms1/STARS, a novel gene involved in cardiac development and disease, is regulated by GATA4. Mol Cell Biol (2012) 0.85

Developing insights into cardiac regeneration. Development (2013) 0.85

Role of GATA factors in development, differentiation, and homeostasis of the small intestinal epithelium. Am J Physiol Gastrointest Liver Physiol (2014) 0.83

Reduced bone mineralization in adolescent survivors of malignant bone tumors: comparison of quantitative ultrasound and dual-energy x-ray absorptiometry. J Pediatr Hematol Oncol (2003) 0.81

Cardiomyocyte-enriched protein CIP protects against pathophysiological stresses and regulates cardiac homeostasis. J Clin Invest (2015) 0.80

Reprogramming fibroblasts into cardiomyocytes. N Engl J Med (2011) 0.78

Novel interaction at the Cdx-2 binding sites of the lactase-phlorizin hydrolase promoter. Biochem Biophys Res Commun (2002) 0.78

GATA factors promote ER integrity and β-cell survival and contribute to type 1 diabetes risk. Mol Endocrinol (2013) 0.78

Developmental expression of Eph and ephrin family genes in mammalian small intestine. Dig Dis Sci (2010) 0.78

Regulatory regions in the rat lactase-phlorizin hydrolase gene that control cell-specific expression. J Pediatr Gastroenterol Nutr (2004) 0.78

HCN4 charges up the first heart field. Circ Res (2013) 0.77

Lactose and lactase--who is lactose intolerant and why? J Pediatr Gastroenterol Nutr (2007) 0.77

Hippo activation in arrhythmogenic cardiomyopathy. Circ Res (2014) 0.76

Developmental and regional expression and localization of mRNAs encoding proteins involved in RNA translocation. J Histochem Cytochem (2005) 0.76

Characterization of expression in mice of a transgene containing 3.3 kb of the human lactase-phlorizin hydrolase (LPH) 5' flanking sequence. Dig Dis Sci (2010) 0.75