Published in Biol Open on June 12, 2017
Embryonic stem cell lines derived from human blastocysts. Science (1998) 65.53
Efficient differentiation of human embryonic stem cells to definitive endoderm. Nat Biotechnol (2005) 9.58
Opening of compacted chromatin by early developmental transcription factors HNF3 (FoxA) and GATA-4. Mol Cell (2002) 8.59
Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis. Genes Dev (1997) 6.52
Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells. Hepatology (2010) 6.40
GATA4 transcription factor is required for ventral morphogenesis and heart tube formation. Genes Dev (1997) 5.51
The zinc finger-containing transcription factors GATA-4, -5, and -6. Ubiquitously expressed regulators of tissue-specific gene expression. J Biol Chem (2000) 5.02
GATA6 regulates HNF4 and is required for differentiation of visceral endoderm in the mouse embryo. Genes Dev (1998) 4.72
Depletion of definitive gut endoderm in Sox17-null mutant mice. Development (2002) 4.13
GATA-4/5/6, a subfamily of three transcription factors transcribed in developing heart and gut. J Biol Chem (1994) 3.65
Induction and monitoring of definitive and visceral endoderm differentiation of mouse ES cells. Nat Biotechnol (2005) 3.55
GATA-6: a zinc finger transcription factor that is expressed in multiple cell lineages derived from lateral mesoderm. Dev Biol (1996) 3.46
The transcription factor GATA6 is essential for early extraembryonic development. Development (1999) 3.19
GATA4 is essential for formation of the proepicardium and regulates cardiogenesis. Proc Natl Acad Sci U S A (2004) 3.08
Activin a efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed. Stem Cells (2007) 3.04
Cerberus-like is a secreted factor with neutralizing activity expressed in the anterior primitive endoderm of the mouse gastrula. Mech Dev (1997) 2.83
Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer. Nature (1996) 2.54
Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice. Dev Biol (2008) 2.34
Pioneer factors, genetic competence, and inductive signaling: programming liver and pancreas progenitors from the endoderm. Cold Spring Harb Symp Quant Biol (2008) 2.34
Sox17 and beta-catenin cooperate to regulate the transcription of endodermal genes. Development (2004) 2.33
Pluripotency factors regulate definitive endoderm specification through eomesodermin. Genes Dev (2011) 2.22
end-1 encodes an apparent GATA factor that specifies the endoderm precursor in Caenorhabditis elegans embryos. Genes Dev (1997) 2.22
The homeobox gene Hex is required in definitive endodermal tissues for normal forebrain, liver and thyroid formation. Development (2000) 2.22
GATA transcription factors as potentiators of gut endoderm differentiation. Development (1998) 2.20
Sox17 regulates organ lineage segregation of ventral foregut progenitor cells. Dev Cell (2009) 2.14
Gata4 regulates the formation of multiple organs. Development (2005) 2.02
GATA6 is essential for embryonic development of the liver but dispensable for early heart formation. Mol Cell Biol (2005) 2.00
Developmental competence of the gut endoderm: genetic potentiation by GATA and HNF3/fork head proteins. Dev Biol (1999) 1.95
Use of in vivo biotinylation to study protein-protein and protein-DNA interactions in mouse embryonic stem cells. Nat Protoc (2009) 1.94
Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse. Development (2008) 1.94
Differential roles of Sall4 isoforms in embryonic stem cell pluripotency. Mol Cell Biol (2010) 1.88
An early developmental transcription factor complex that is more stable on nucleosome core particles than on free DNA. Mol Cell (1999) 1.86
Re-employment of developmental transcription factors in adult heart disease. Semin Cell Dev Biol (2006) 1.82
GATA6 regulates differentiation of distal lung epithelium. Development (2002) 1.82
Hex homeobox gene controls the transition of the endoderm to a pseudostratified, cell emergent epithelium for liver bud development. Dev Biol (2005) 1.80
A molecular pathway leading to endoderm formation in zebrafish. Curr Biol (1999) 1.76
Development of the mammalian liver and ventral pancreas is dependent on GATA4. BMC Dev Biol (2007) 1.75
Wild-type endoderm abrogates the ventral developmental defects associated with GATA-4 deficiency in the mouse. Dev Biol (1997) 1.70
SOX17 links gut endoderm morphogenesis and germ layer segregation. Nat Cell Biol (2014) 1.66
Culture of human pluripotent stem cells using completely defined conditions on a recombinant E-cadherin substratum. BMC Dev Biol (2010) 1.64
Gata6 is an important regulator of mouse pancreas development. Dev Biol (2006) 1.58
Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis. J Clin Invest (2012) 1.55
HNF4A is essential for specification of hepatic progenitors from human pluripotent stem cells. Development (2011) 1.50
GATA4 and GATA6 control mouse pancreas organogenesis. J Clin Invest (2012) 1.41
GATA4 is essential for jejunal function in mice. Gastroenterology (2008) 1.39
Multiple roles for Gata5 in zebrafish endoderm formation. Development (2001) 1.37
Generation of mice harbouring a conditional loss-of-function allele of Gata6. BMC Dev Biol (2006) 1.35
The transcription factor GATA6 is essential for branching morphogenesis and epithelial cell differentiation during fetal pulmonary development. Development (2001) 1.34
The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation. Nat Cell Biol (2011) 1.33
The transcription factor GATA-6 regulates pathological cardiac hypertrophy. Circ Res (2010) 1.32
Redundancy and evolution of GATA factor requirements in development of the myocardium. Dev Biol (2007) 1.31
Transcription factor binding dynamics during human ES cell differentiation. Nature (2015) 1.30
Induction of the mesendoderm in the zebrafish germ ring by yolk cell-derived TGF-beta family signals and discrimination of mesoderm and endoderm by FGF. Development (1999) 1.28
Gata4 directs development of cardiac-inducing endoderm from ES cells. Dev Biol (2009) 1.23
Transcription factor GATA-6 is expressed in the endocrine and GATA-4 in the exocrine pancreas. Mol Cell Endocrinol (2004) 1.23
GATA factors regulate proliferation, differentiation, and gene expression in small intestine of mature mice. Gastroenterology (2011) 1.18
Differentiation of hepatocytes from pluripotent stem cells. Curr Protoc Stem Cell Biol (2013) 1.14
Gata4 is necessary for normal pulmonary lobar development. Am J Respir Cell Mol Biol (2006) 1.09
A role for GATA5 in Xenopus endoderm specification. Development (2000) 1.07
GATA4, 5 and 6 mediate TGFbeta maintenance of endodermal gene expression in Xenopus embryos. Development (2005) 1.06
GATA-6 mediates human bladder smooth muscle differentiation: involvement of a novel enhancer element in regulating alpha-smooth muscle actin gene expression. Am J Physiol Cell Physiol (2007) 1.04
GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol (2014) 1.03
Dual lineage-specific expression of Sox17 during mouse embryogenesis. Stem Cells (2012) 1.03
Gata6 is required for complete acinar differentiation and maintenance of the exocrine pancreas in adult mice. Gut (2012) 1.02
A gene regulatory network controlling hhex transcription in the anterior endoderm of the organizer. Dev Biol (2011) 0.97
Gata4 and Hnf1alpha are partially required for the expression of specific intestinal genes during development. Am J Physiol Gastrointest Liver Physiol (2007) 0.96
Cooperation between GATA4 and TGF-beta signaling regulates intestinal epithelial gene expression. Am J Physiol Gastrointest Liver Physiol (2007) 0.94
Direct transcriptional regulation of Gata4 during early endoderm specification is controlled by FoxA2 binding to an intronic enhancer. Dev Biol (2010) 0.93
GATA6 is required for proliferation, migration, secretory cell maturation, and gene expression in the mature mouse colon. Mol Cell Biol (2012) 0.93
Eomesodermin is a localized maternal determinant required for endoderm induction in zebrafish. Dev Cell (2005) 0.92
GATA4 loss in the septum transversum mesenchyme promotes liver fibrosis in mice. Hepatology (2014) 0.89
Tandem affinity purification of protein complexes in mouse embryonic stem cells using in vivo biotinylation. Curr Protoc Stem Cell Biol (2009) 0.89
Cell fate control by pioneer transcription factors. Development (2016) 0.85
A molecular signature for purified definitive endoderm guides differentiation and isolation of endoderm from mouse and human embryonic stem cells. Stem Cells Dev (2012) 0.81
Expression of GATA-binding transcription factors in rat hepatocytes. FEBS Lett (1994) 0.79
Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development. Cell Stem Cell (2017) 0.79
GATA6 Plays an Important Role in the Induction of Human Definitive Endoderm, Development of the Pancreas, and Functionality of Pancreatic β Cells. Stem Cell Reports (2017) 0.75