Published in Eur J Immunol on February 10, 2011
Role of Hedgehog signalling at the transition from double-positive to single-positive thymocyte. Eur J Immunol (2011) 0.97
CD4-CD8 differentiation in the thymus: connecting circuits and building memories. Curr Opin Immunol (2012) 0.96
The transcription factors Thpok and LRF are necessary and partly redundant for T helper cell differentiation. Immunity (2012) 0.88
A silencer-proximal intronic region is required for sustained CD4 expression in postselection thymocytes. J Immunol (2014) 0.84
Identification of lineage-specifying cytokines that signal all CD8(+)-cytotoxic-lineage-fate 'decisions' in the thymus. Nat Immunol (2017) 0.75
Positive and negative selection of T cells. Annu Rev Immunol (2002) 8.32
Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro. Immunity (2002) 8.17
The transcription factor PLZF directs the effector program of the NKT cell lineage. Immunity (2008) 4.68
Kruppel-like factor 2 regulates thymocyte and T-cell migration. Nature (2006) 4.51
The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment. Nature (2005) 4.39
The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions. Nat Immunol (2008) 4.15
CD8 is needed for development of cytotoxic T cells but not helper T cells. Cell (1991) 4.05
The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection. Nat Immunol (2005) 3.74
Critical roles for transcription factor GATA-3 in thymocyte development. Immunity (2003) 3.15
Lineage fate and intense debate: myths, models and mechanisms of CD4- versus CD8-lineage choice. Nat Rev Immunol (2008) 2.98
E and ID proteins branch out. Nat Rev Immunol (2009) 2.68
GATA-3 expression is controlled by TCR signals and regulates CD4/CD8 differentiation. Immunity (2003) 2.63
Sequential roles of Brg, the ATPase subunit of BAF chromatin remodeling complexes, in thymocyte development. Immunity (2003) 2.56
The chromatin remodeler Mi-2beta is required for CD4 expression and T cell development. Immunity (2004) 2.54
The regulation of the expression of gp39, the CD40 ligand, on normal and cloned CD4+ T cells. J Immunol (1993) 2.53
RUNX proteins in transcription factor networks that regulate T-cell lineage choice. Nat Rev Immunol (2009) 2.49
TOX: an HMG box protein implicated in the regulation of thymocyte selection. Nat Immunol (2002) 2.44
GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol (2009) 2.43
Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development. Science (2008) 2.43
Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4(+) T cells. Nat Immunol (2008) 2.29
ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage. Nat Immunol (2008) 2.19
Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells. Nat Immunol (2010) 2.19
Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling. Nat Immunol (2009) 2.12
Thymocyte selection is regulated by the helix-loop-helix inhibitor protein, Id3. Immunity (2000) 2.05
Themis, a T cell-specific protein important for late thymocyte development. Nat Immunol (2009) 2.00
Shared dependence on the DNA-binding factor TOX for the development of lymphoid tissue-inducer cell and NK cell lineages. Nat Immunol (2010) 1.97
Epigenetic silencing of CD4 in T cells committed to the cytotoxic lineage. Nat Genet (2001) 1.95
Development of all CD4 T lineages requires nuclear factor TOX. J Exp Med (2008) 1.94
The cunning little vixen: Foxo and the cycle of life and death. Nat Immunol (2009) 1.91
Critical functions for c-Myb at three checkpoints during thymocyte development. Nat Immunol (2004) 1.91
A heterodimer of HEB and an E12-related protein interacts with the CD4 enhancer and regulates its activity in T-cell lines. Mol Cell Biol (1993) 1.89
Cascading suppression of transcriptional silencers by ThPOK seals helper T cell fate. Nat Immunol (2008) 1.89
Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection. Nat Immunol (2009) 1.84
Coreceptor reversal in the thymus: signaled CD4+8+ thymocytes initially terminate CD8 transcription even when differentiating into CD8+ T cells. Immunity (2000) 1.83
Decision checkpoints in the thymus. Nat Immunol (2010) 1.75
Acquisition of a functional T cell receptor during T lymphocyte development is enforced by HEB and E2A transcription factors. Immunity (2007) 1.68
Development of promyelocytic zinc finger and ThPOK-expressing innate gamma delta T cells is controlled by strength of TCR signaling and Id3. J Immunol (2009) 1.64
GATA-3 regulates the development and function of invariant NKT cells. J Immunol (2006) 1.57
The zinc finger transcription factor Zbtb7b represses CD8-lineage gene expression in peripheral CD4+ T cells. Immunity (2008) 1.55
Expression of the transcription factor GATA-3 is required for the development of the earliest T cell progenitors and correlates with stages of cellular proliferation in the thymus. Eur J Immunol (1999) 1.52
Foxp1 is an essential transcriptional regulator for the generation of quiescent naive T cells during thymocyte development. Blood (2009) 1.42
Gasp, a Grb2-associating protein, is critical for positive selection of thymocytes. Proc Natl Acad Sci U S A (2009) 1.37
Epigenetic propagation of CD4 expression is established by the Cd4 proximal enhancer in helper T cells. Genes Dev (2010) 1.37
Regulation of lineage commitment distinct from positive selection. Science (1999) 1.36
A novel gene essential for the development of single positive thymocytes. Mol Cell Biol (2009) 1.32
The transcription factor Zbtb7b promotes CD4 expression by antagonizing Runx-mediated activation of the CD4 silencer. J Immunol (2007) 1.28
The zinc-finger protein MAZR is part of the transcription factor network that controls the CD4 versus CD8 lineage fate of double-positive thymocytes. Nat Immunol (2010) 1.28
c-Myb regulates lineage choice in developing thymocytes via its target gene Gata3. EMBO J (2007) 1.27
The transcription factor c-Myb primes CD4+CD8+ immature thymocytes for selection into the iNKT lineage. Nat Immunol (2010) 1.25
TOX provides a link between calcineurin activation and CD8 lineage commitment. J Exp Med (2004) 1.24
CD4-CD8 lineage differentiation: Thpok-ing into the nucleus. J Immunol (2009) 1.21
Expression of the transcription factor cKrox in peripheral CD8 T cells reveals substantial postthymic plasticity in CD4-CD8 lineage differentiation. J Exp Med (2007) 1.20
c-Krox, a transcriptional regulator of type I collagen gene expression, is preferentially expressed in skin. Proc Natl Acad Sci U S A (1994) 1.15
Stepwise specification of lymphocyte developmental lineages. Curr Opin Genet Dev (2000) 1.15
Thymic microenvironments for T-cell repertoire formation. Adv Immunol (2008) 1.11
Co-receptor choice by V alpha14i NKT cells is driven by Th-POK expression rather than avoidance of CD8-mediated negative selection. J Exp Med (2010) 1.11
Unraveling a revealing paradox: Why major histocompatibility complex I-signaled thymocytes "paradoxically" appear as CD4+8lo transitional cells during positive selection of CD8+ T cells. J Exp Med (2003) 1.10
The role of ThPOK in control of CD4/CD8 lineage commitment. Annu Rev Immunol (2010) 1.10
The sequential activity of Gata3 and Thpok is required for the differentiation of CD1d-restricted CD4+ NKT cells. Eur J Immunol (2010) 1.07
Restricting Zap70 expression to CD4+CD8+ thymocytes reveals a T cell receptor-dependent proofreading mechanism controlling the completion of positive selection. J Exp Med (2003) 1.07
Notch signaling in CD4 and CD8 T cell development. Curr Opin Immunol (2008) 1.06
c-Myb promotes the survival of CD4+CD8+ double-positive thymocytes through upregulation of Bcl-xL. J Immunol (2010) 1.05
TCR-mediated ThPOK induction promotes development of mature (CD24-) gammadelta thymocytes. EMBO J (2010) 0.99
GATA3 controls the expression of CD5 and the T cell receptor during CD4 T cell lineage development. Eur J Immunol (2007) 0.91
Tenuous paths in unexplored territory: From T cell receptor signaling to effector gene expression during thymocyte selection. Semin Immunol (2010) 0.88
Gene expression profiling in mice with enforced Gata3 expression reveals putative targets of Gata3 in double positive thymocytes. Mol Immunol (2009) 0.82
The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection. Nat Immunol (2005) 3.74
Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4(+) T cells. Nat Immunol (2008) 2.29
Decision checkpoints in the thymus. Nat Immunol (2010) 1.75
The zinc finger transcription factor Zbtb7b represses CD8-lineage gene expression in peripheral CD4+ T cells. Immunity (2008) 1.55
Duration of TCR signaling controls CD4-CD8 lineage differentiation in vivo. Nat Immunol (2004) 1.39
The transcription factor Zbtb7b promotes CD4 expression by antagonizing Runx-mediated activation of the CD4 silencer. J Immunol (2007) 1.28
The transcription factor Ets1 is important for CD4 repression and Runx3 up-regulation during CD8 T cell differentiation in the thymus. J Exp Med (2009) 1.22
CD4-CD8 lineage differentiation: Thpok-ing into the nucleus. J Immunol (2009) 1.21
Expression of the transcription factor cKrox in peripheral CD8 T cells reveals substantial postthymic plasticity in CD4-CD8 lineage differentiation. J Exp Med (2007) 1.20
The sequential activity of Gata3 and Thpok is required for the differentiation of CD1d-restricted CD4+ NKT cells. Eur J Immunol (2010) 1.07
Restricting Zap70 expression to CD4+CD8+ thymocytes reveals a T cell receptor-dependent proofreading mechanism controlling the completion of positive selection. J Exp Med (2003) 1.07
Analyzing expression of perforin, Runx3, and Thpok genes during positive selection reveals activation of CD8-differentiation programs by MHC II-signaled thymocytes. J Immunol (2005) 1.05
CD4-CD8 differentiation in the thymus: connecting circuits and building memories. Curr Opin Immunol (2012) 0.96
The transcription factors Thpok and LRF are necessary and partly redundant for T helper cell differentiation. Immunity (2012) 0.88
Tenuous paths in unexplored territory: From T cell receptor signaling to effector gene expression during thymocyte selection. Semin Immunol (2010) 0.88
CBFB-MYH11 hinders early T-cell development and induces massive cell death in the thymus. Blood (2006) 0.87
Thpok-independent repression of Runx3 by Gata3 during CD4+ T-cell differentiation in the thymus. Eur J Immunol (2013) 0.80
Gimap and T cells: a matter of life or death. Eur J Immunol (2014) 0.78
Maintaining CD4-CD8 lineage integrity in T cells: where plasticity serves versatility. Semin Immunol (2011) 0.78
Genetic Tools to Study T Cell Development. Methods Mol Biol (2016) 0.78
Retroviral TCR gene transduction: 2A for two. Nat Methods (2006) 0.78
200 Million Thymocytes and I: A Beginner's Survival Guide to T Cell Development. Methods Mol Biol (2016) 0.76
T cell metabolism: microRNAs cap PTEN to feed the expanding crowd. Immunity (2013) 0.75
Purification of Thymocyte and T Cell Subsets. Methods Mol Biol (2016) 0.75
[Interleukin 22 may represent a new therapeutic tool towards thymic regeneration in vivo]. Med Sci (Paris) (2013) 0.75
In Vitro Analyses of T Cell Effector Differentiation. Methods Mol Biol (2016) 0.75
Preface. T-Cell Development. Methods Mol Biol (2016) 0.75