Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells.

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Published in Nat Immunol on January 31, 2010

Authors

Jung-Hyun Park1, Stanley Adoro, Terry Guinter, Batu Erman, Amala S Alag, Marta Catalfamo, Motoko Y Kimura, Yongzhi Cui, Philip J Lucas, Ronald E Gress, Masato Kubo, Lothar Hennighausen, Lionel Feigenbaum, Alfred Singer

Author Affiliations

1: Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.

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