Published in J Pharmacol Sci on February 22, 2011
Pharmacological characterization of uracil nucleotide-preferring P2Y receptors modulating intestinal motility: a study on mouse ileum. Purinergic Signal (2011) 0.81
Ca(2+) dependent but PKC independent signalling mediates UTP induced contraction of rat mesenteric arteries. J Smooth Muscle Res (2015) 0.77
Regulation of tight junctions during the epithelium-mesenchyme transition: direct repression of the gene expression of claudins/occludin by Snail. J Cell Sci (2003) 3.79
Nitric oxide activates TRP channels by cysteine S-nitrosylation. Nat Chem Biol (2006) 3.66
Coupling of STIM1 to store-operated Ca2+ entry through its constitutive and inducible movement in the endoplasmic reticulum. Proc Natl Acad Sci U S A (2006) 3.47
LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death. Mol Cell (2002) 3.36
A unified nomenclature for the superfamily of TRP cation channels. Mol Cell (2002) 2.99
TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration. Nat Med (2008) 2.77
Self-renewing hematopoietic stem cell is the primary target in pathogenesis of human chronic lymphocytic leukemia. Cancer Cell (2011) 2.62
The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages. Genes Dev (2006) 2.62
Bcl6 protein expression shapes pre-germinal center B cell dynamics and follicular helper T cell heterogeneity. Immunity (2011) 2.60
TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy. EMBO J (2006) 2.28
TRPM2 activation by cyclic ADP-ribose at body temperature is involved in insulin secretion. EMBO J (2006) 2.21
TRPM1 is a component of the retinal ON bipolar cell transduction channel in the mGluR6 cascade. Proc Natl Acad Sci U S A (2009) 2.20
Transient receptor potential channels in cardiovascular function and disease. Circ Res (2006) 2.20
Upregulation of TRPC1 in the development of cardiac hypertrophy. J Mol Cell Cardiol (2006) 2.17
Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound. Proc Natl Acad Sci U S A (2009) 2.08
Mutations in EFHC1 cause juvenile myoclonic epilepsy. Nat Genet (2004) 1.98
RIM1 confers sustained activity and neurotransmitter vesicle anchoring to presynaptic Ca2+ channels. Nat Neurosci (2007) 1.95
Multiple regulation by calcium of murine homologues of transient receptor potential proteins TRPC6 and TRPC7 expressed in HEK293 cells. J Physiol (2004) 1.91
Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia. Nat Neurosci (2009) 1.75
Transient receptor potential 1 regulates capacitative Ca(2+) entry and Ca(2+) release from endoplasmic reticulum in B lymphocytes. J Exp Med (2002) 1.73
Early changes in KCC2 phosphorylation in response to neuronal stress result in functional downregulation. J Neurosci (2007) 1.72
TRPM2 functions as a lysosomal Ca2+-release channel in beta cells. Sci Signal (2009) 1.71
STIM protein coupling in the activation of Orai channels. Proc Natl Acad Sci U S A (2009) 1.70
A child with influenza A (H1N1)-associated myocarditis rescued by extracorporeal membrane oxygenation. J Artif Organs (2010) 1.62
Is a 6-week course of ganciclovir therapy effective for chorioretinitis in infants with congenital cytomegalovirus infection? J Pediatr (2010) 1.60
Lysosomal turnover of GABARAP-phospholipid conjugate is activated during differentiation of C2C12 cells to myotubes without inactivation of the mTor kinase-signaling pathway. Autophagy (2006) 1.60
FLT3-ITD up-regulates MCL-1 to promote survival of stem cells in acute myeloid leukemia via FLT3-ITD-specific STAT5 activation. Blood (2009) 1.59
Molecular characterization of TRPA1 channel activation by cysteine-reactive inflammatory mediators. Channels (Austin) (2008) 1.59
Purification, gene cloning, gene expression, and mutants of Dps from the obligate anaerobe Porphyromonas gingivalis. Infect Immun (2003) 1.57
Involvement of TRPM7 in cell growth as a spontaneously activated Ca2+ entry pathway in human retinoblastoma cells. J Pharmacol Sci (2004) 1.56
Cyclosporin and Timothy syndrome increase mode 2 gating of CaV1.2 calcium channels through aberrant phosphorylation of S6 helices. Proc Natl Acad Sci U S A (2006) 1.55
The TRPC3 channel has a large internal chamber surrounded by signal sensing antennas. J Mol Biol (2006) 1.54
Long-term low-dose spironolactone therapy is safe in oligoanuric hemodialysis patients. Cardiology (2009) 1.49
TRPA1 underlies a sensing mechanism for O2. Nat Chem Biol (2011) 1.47
Differential redox regulation of ORAI ion channels: a mechanism to tune cellular calcium signaling. Sci Signal (2010) 1.44
Volume-regulated anion channels serve as an auto/paracrine nucleotide release pathway in aortic endothelial cells. J Gen Physiol (2002) 1.41
TRPM7 channels in hippocampal neurons detect levels of extracellular divalent cations. Proc Natl Acad Sci U S A (2007) 1.37
Solution structure of microtubule-associated protein light chain 3 and identification of its functional subdomains. J Biol Chem (2005) 1.36
Human Flt3 is expressed at the hematopoietic stem cell and the granulocyte/macrophage progenitor stages to maintain cell survival. J Immunol (2008) 1.32
TRPM2 links oxidative stress to NLRP3 inflammasome activation. Nat Commun (2013) 1.32
A critical role of TRPM2 in neuronal cell death by hydrogen peroxide. J Pharmacol Sci (2006) 1.31
Lack of TRPM2 impaired insulin secretion and glucose metabolisms in mice. Diabetes (2010) 1.29
G alpha 12/13- and reactive oxygen species-dependent activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase by angiotensin receptor stimulation in rat neonatal cardiomyocytes. J Biol Chem (2005) 1.27
Roles of TRPM2 in oxidative stress. Cell Calcium (2011) 1.26
Genetically encoded fluorescent thermosensors visualize subcellular thermoregulation in living cells. Nat Methods (2013) 1.25
Roles of anti-hemagglutinin IgA and IgG antibodies in different sites of the respiratory tract of vaccinated mice in preventing lethal influenza pneumonia. Vaccine (2003) 1.23
Synergistic activation of vascular TRPC6 channel by receptor and mechanical stimulation via phospholipase C/diacylglycerol and phospholipase A2/omega-hydroxylase/20-HETE pathways. Circ Res (2009) 1.23
Activation of RasGRP3 by phosphorylation of Thr-133 is required for B cell receptor-mediated Ras activation. Proc Natl Acad Sci U S A (2004) 1.22
Tetrameric Orai1 is a teardrop-shaped molecule with a long, tapered cytoplasmic domain. J Biol Chem (2009) 1.21
Galpha12/13-mediated up-regulation of TRPC6 negatively regulates endothelin-1-induced cardiac myofibroblast formation and collagen synthesis through nuclear factor of activated T cells activation. J Biol Chem (2007) 1.21
Ca2+-dependent induction of TRPM2 currents in hippocampal neurons. J Physiol (2009) 1.19
Nitric oxide-cGMP-protein kinase G pathway negatively regulates vascular transient receptor potential channel TRPC6. J Physiol (2008) 1.19
Building the posterior lateral line system in zebrafish. Dev Neurobiol (2012) 1.18
Bidirectional alterations in cerebellar synaptic transmission of tottering and rolling Ca2+ channel mutant mice. J Neurosci (2002) 1.17
GABAA receptor phospho-dependent modulation is regulated by phospholipase C-related inactive protein type 1, a novel protein phosphatase 1 anchoring protein. J Neurosci (2004) 1.17
Three-dimensional reconstruction using transmission electron microscopy reveals a swollen, bell-shaped structure of transient receptor potential melastatin type 2 cation channel. J Biol Chem (2007) 1.16
Membrane stretch-induced activation of a TRPM4-like nonselective cation channel in cerebral artery myocytes. J Pharmacol Sci (2007) 1.15
The receptor LMIR3 negatively regulates mast cell activation and allergic responses by binding to extracellular ceramide. Immunity (2012) 1.15
Bifidobacterium septicemia associated with postoperative probiotic therapy in a neonate with omphalocele. J Pediatr (2010) 1.14
TRPM1: a vertebrate TRP channel responsible for retinal ON bipolar function. Cell Calcium (2010) 1.13
Galpha(12/13) mediates alpha(1)-adrenergic receptor-induced cardiac hypertrophy. Circ Res (2002) 1.13
Inhibition of TRPC6 channel activity contributes to the antihypertrophic effects of natriuretic peptides-guanylyl cyclase-A signaling in the heart. Circ Res (2010) 1.12
Amplification of receptor signalling by Ca2+ entry-mediated translocation and activation of PLCgamma2 in B lymphocytes. EMBO J (2003) 1.11
Depletion of intracellular Ca2+ store itself may be a major factor in thapsigargin-induced ER stress and apoptosis in PC12 cells. Neurochem Int (2006) 1.09
Role of the PLC-related, catalytically inactive protein p130 in GABA(A) receptor function. EMBO J (2002) 1.08
Oligo-Asp tag/Zn(II) complex probe as a new pair for labeling and fluorescence imaging of proteins. J Am Chem Soc (2006) 1.08
Comprehensive analysis of the ascidian genome reveals novel insights into the molecular evolution of ion channel genes. Physiol Genomics (2005) 1.08
FPL 64176 modification of Ca(V)1.2 L-type calcium channels: dissociation of effects on ionic current and gating current. Biophys J (2004) 1.08
Hydrogen peroxide stimulates tetrahydrobiopterin synthesis through the induction of GTP-cyclohydrolase I and increases nitric oxide synthase activity in vascular endothelial cells. Free Radic Biol Med (2003) 1.07
Targeted disruption of the voltage-dependent calcium channel alpha2/delta-1-subunit. Am J Physiol Heart Circ Physiol (2009) 1.07
Do pluripotent stem cells exist in adult mice as very small embryonic stem cells? Stem Cell Reports (2013) 1.06
Dendritic cell maturation and chemotaxis is regulated by TRPM2-mediated lysosomal Ca2+ release. FASEB J (2011) 1.04
The non-selective cation-permeable channel TRPC3 is a tetrahedron with a cap on the large cytoplasmic end. Biochem Biophys Res Commun (2005) 1.03
Changes in temperature preferences and energy homeostasis in dystroglycan mutants. Science (2009) 1.03
Molecules interacting with PRIP-2, a novel Ins(1,4,5)P3 binding protein type 2: Comparison with PRIP-1. Life Sci (2002) 1.02