Robert C Read

Author PubWeight™ 98.07‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Immunogenicity and safety of a two-dose schedule of whole-virion and AS03A-adjuvanted 2009 influenza A (H1N1) vaccines: a randomised, multicentre, age-stratified, head-to-head trial. Lancet Infect Dis 2010 2.67
2 Moxifloxacin monotherapy is effective in hospitalized patients with community-acquired pneumonia: the MOTIV study--a randomized clinical trial. Clin Infect Dis 2008 2.09
3 Identification of in vivo-expressed antigens of Staphylococcus aureus and their use in vaccinations for protection against nasal carriage. J Infect Dis 2006 1.99
4 Severity of meningococcal disease associated with genomic bacterial load. Clin Infect Dis 2009 1.92
5 Clinical and laboratory features distinguishing pandemic H1N1 influenza-related pneumonia from interpandemic community-acquired pneumonia in adults. Thorax 2011 1.91
6 Pneumococcal disease in HIV-infected Malawian adults: acute mortality and long-term survival. AIDS 2002 1.79
7 Community-acquired pneumonia mortality: a potential link to antibiotic prescribing trends in general practice. Respir Med 2004 1.76
8 Methylation status of a single CpG site in the IL6 promoter is related to IL6 messenger RNA levels and rheumatoid arthritis. Arthritis Rheum 2008 1.73
9 Age-related loss of CpG methylation in the tumour necrosis factor promoter. Cytokine 2011 1.58
10 Toll-like receptors in health and disease: complex questions remain. J Immunol 2003 1.57
11 Flavohemoglobin Hmp protects Salmonella enterica serovar typhimurium from nitric oxide-related killing by human macrophages. Infect Immun 2002 1.53
12 Genetic polymorphism of the binding domain of surfactant protein-A2 increases susceptibility to meningococcal disease. Clin Infect Dis 2006 1.51
13 Nitric oxide metabolism in Neisseria meningitidis. J Bacteriol 2002 1.49
14 Differences between asthmatics and nonasthmatics hospitalised with influenza A infection. Eur Respir J 2012 1.44
15 Management of meningitis. Clin Med 2005 1.43
16 Dynamic changes in Mcl-1 expression regulate macrophage viability or commitment to apoptosis during bacterial clearance. J Clin Invest 2005 1.42
17 Nitric oxide in chemostat-cultured Escherichia coli is sensed by Fnr and other global regulators: unaltered methionine biosynthesis indicates lack of S nitrosation. J Bacteriol 2006 1.42
18 Predictors of clinical outcome in a national hospitalised cohort across both waves of the influenza A/H1N1 pandemic 2009-2010 in the UK. Thorax 2012 1.40
19 Nitric oxide detoxification systems enhance survival of Neisseria meningitidis in human macrophages and in nasopharyngeal mucosa. Infect Immun 2005 1.37
20 Strategies to increase influenza vaccination rates: outcomes of a nationwide cross-sectional survey of UK general practice. BMJ Open 2012 1.37
21 Nitric oxide levels regulate macrophage commitment to apoptosis or necrosis during pneumococcal infection. FASEB J 2004 1.33
22 Interaction of the Salmonella typhimurium transcription and virulence factor SlyA with target DNA and identification of members of the SlyA regulon. J Biol Chem 2002 1.32
23 Streptococcus pneumoniae-associated human macrophage apoptosis after bacterial internalization via complement and Fcgamma receptors correlates with intracellular bacterial load. J Infect Dis 2003 1.28
24 Invasion by Neisseria meningitidis varies widely between clones and among nasopharyngeal mucosae derived from adult human hosts. Microbiology 2002 1.17
25 Regulation of denitrification genes in Neisseria meningitidis by nitric oxide and the repressor NsrR. J Bacteriol 2006 1.14
26 Neisseria meningitidis lactate permease is required for nasopharyngeal colonization. Infect Immun 2005 1.11
27 The pathogen Neisseria meningitidis requires oxygen, but supplements growth by denitrification. Nitrite, nitric oxide and oxygen control respiratory flux at genetic and metabolic levels. Mol Microbiol 2005 1.10
28 Activation of toll-like receptor 2 (TLR2) and TLR4/MD2 by Neisseria is independent of capsule and lipooligosaccharide (LOS) sialylation but varies widely among LOS from different strains. Infect Immun 2003 1.09
29 NsrR: a key regulator circumventing Salmonella enterica serovar Typhimurium oxidative and nitrosative stress in vitro and in IFN-gamma-stimulated J774.2 macrophages. Microbiology 2007 1.08
30 Oseltamivir, zanamivir and amantadine in the prevention of influenza: a systematic review. J Infect 2010 1.06
31 A functional microsatellite of the macrophage migration inhibitory factor gene associated with meningococcal disease. FASEB J 2011 1.05
32 Nasopharyngeal colonization by Neisseria lactamica and induction of protective immunity against Neisseria meningitidis. Clin Infect Dis 2011 1.04
33 Inhibition of macrophage apoptosis by Neisseria meningitidis requires nitric oxide detoxification mechanisms. Infect Immun 2006 1.04
34 Host genetics and outcome in meningococcal disease: a systematic review and meta-analysis. Lancet Infect Dis 2010 1.03
35 Mannose-binding lectin enhances phagocytosis and killing of Neisseria meningitidis by human macrophages. J Leukoc Biol 2004 1.03
36 A cardinal role for cathepsin d in co-ordinating the host-mediated apoptosis of macrophages and killing of pneumococci. PLoS Pathog 2011 1.02
37 Pulmonary immunoglobulin responses to Streptococcus pneumoniae are altered but not reduced in human immunodeficiency virus-infected Malawian adults. J Infect Dis 2003 1.02
38 Characterisation of receptor binding by the chemotaxis inhibitory protein of Staphylococcus aureus and the effects of the host immune response. Mol Immunol 2007 1.01
39 Primary macrophages from HIV-infected adults show dysregulated cytokine responses to Salmonella, but normal internalization and killing. AIDS 2007 1.01
40 The hmp gene encoding the NO-inducible flavohaemoglobin in Escherichia coli confers a protective advantage in resisting killing within macrophages, but not in vitro: links with swarming motility. Gene 2007 1.01
41 Distinct cell death programs in monocytes regulate innate responses following challenge with common causes of invasive bacterial disease. J Immunol 2010 1.01
42 Metabolism of nitric oxide by Neisseria meningitidis modifies release of NO-regulated cytokines and chemokines by human macrophages. Microbes Infect 2007 0.99
43 Peroxynitrite toxicity in Escherichia coli K12 elicits expression of oxidative stress responses and protein nitration and nitrosylation. J Biol Chem 2010 0.99
44 Nosocomial pandemic (H1N1) 2009, United Kingdom, 2009-2010. Emerg Infect Dis 2011 0.98
45 Superantigen recognition by HLA class II on monocytes up-regulates toll-like receptor 4 and enhances proinflammatory responses to endotoxin. Blood 2005 0.97
46 Post-transcriptional regulation of bacterial motility by aconitase proteins. Mol Microbiol 2004 0.96
47 Gamma interferon enhances internalization and early nonoxidative killing of Salmonella enterica serovar Typhimurium by human macrophages and modifies cytokine responses. Infect Immun 2005 0.96
48 Choline-binding protein A of Streptococcus pneumoniae elicits chemokine production and expression of intercellular adhesion molecule 1 (CD54) by human alveolar epithelial cells. J Infect Dis 2002 0.94
49 Phase I safety and immunogenicity study of a candidate meningococcal disease vaccine based on Neisseria lactamica outer membrane vesicles. Clin Vaccine Immunol 2009 0.93
50 Human microbial challenge: the ultimate animal model. Lancet Infect Dis 2012 0.93
51 Bacterial nitric oxide detoxification prevents host cell S-nitrosothiol formation: a novel mechanism of bacterial pathogenesis. FASEB J 2009 0.92
52 Anti-adhesion methods as novel therapeutics for bacterial infections. Expert Rev Anti Infect Ther 2012 0.91
53 Pre-admission statin use and in-hospital severity of 2009 pandemic influenza A(H1N1) disease. PLoS One 2011 0.91
54 Identification of meningococcal genes necessary for colonization of human upper airway tissue. Infect Immun 2008 0.91
55 Penicillin enhances the toll-like receptor 2-mediated proinflammatory activity of Streptococcus pneumoniae. J Infect Dis 2003 0.90
56 Evidence of a functional B-cell immunodeficiency in adults who experience serogroup C meningococcal disease. Clin Vaccine Immunol 2009 0.89
57 Monocytes regulate the mechanism of T-cell death by inducing Fas-mediated apoptosis during bacterial infection. PLoS Pathog 2012 0.88
58 Comparison of CATs, CURB-65 and PMEWS as triage tools in pandemic influenza admissions to UK hospitals: case control analysis using retrospective data. PLoS One 2012 0.87
59 Distinct roles for tetraspanins CD9, CD63 and CD81 in the formation of multinucleated giant cells. Immunology 2009 0.87
60 The comparative clinical course of pregnant and non-pregnant women hospitalised with influenza A(H1N1)pdm09 infection. PLoS One 2012 0.87
61 Induction of pro-inflammatory cytokine release by human macrophages during exposure of Streptococcus pneumoniae to penicillin is influenced by minimum inhibitory concentration ratio. Int J Antimicrob Agents 2005 0.87
62 Nitrosothiols in bacterial pathogens and pathogenesis. Antioxid Redox Signal 2012 0.86
63 Genetic variation in pro-inflammatory cytokines and meningococcal sepsis. Curr Opin Infect Dis 2010 0.86
64 Chemiluminescence quantification of NO and its derivatives in liquid samples. Methods Enzymol 2008 0.85
65 Respiratory infections. J Med Microbiol 2002 0.85
66 Reduced interleukin-8 response to Streptococcus pneumoniae by alveolar macrophages from adults with HIV/AIDS. AIDS 2005 0.85
67 HIV-1 infection is associated with altered innate pulmonary immunity. J Infect Dis 2005 0.84
68 Response to polysaccharide vaccination amongst pediatric patients with common variable immunodeficiency correlates with clinical disease. Iran J Allergy Asthma Immunol 2008 0.84
69 Analysis of nitric oxide-dependent antimicrobial actions in macrophages and mice. Methods Enzymol 2008 0.84
70 Proteomic evaluation and validation of cathepsin D regulated proteins in macrophages exposed to Streptococcus pneumoniae. Mol Cell Proteomics 2011 0.84
71 Serum bactericidal antibody responses to meningococcal polysaccharide vaccination as a basis for clinical classification of common variable immunodeficiency. Clin Vaccine Immunol 2008 0.84
72 Kinetics of immune responses to nasal challenge with meningococcal polysaccharide one year after serogroup-C glycoconjugate vaccination. Clin Infect Dis 2011 0.83
73 Functional T-cell deficiency in adolescents who experience serogroup C meningococcal disease despite receiving the meningococcal serogroup C conjugate vaccine. Clin Vaccine Immunol 2010 0.82
74 Cooperative role for tetraspanins in adhesin-mediated attachment of bacterial species to human epithelial cells. Infect Immun 2011 0.82
75 Serum bactericidal antibody response to serogroup C polysaccharide meningococcal vaccination in children with primary antibody deficiencies. Vaccine 2007 0.82
76 B-cell-T-cell activation and interaction in common variable immunodeficiency. Hum Immunol 2010 0.81
77 Genetic susceptibility to meningococcal infection. Expert Rev Anti Infect Ther 2013 0.81
78 Increased surface toll-like receptor 2 expression in superantigen shock. Crit Care Med 2008 0.81
79 Adult survivors of invasive pneumococcal disease exhibit defective B cell function. Clin Infect Dis 2011 0.81
80 Challenges for development of meningococcal vaccines in infants and children. Expert Rev Vaccines 2011 0.80
81 Editorial commentary: Vancomycin for your mother, metronidazole for your mother-in-law. J Infect 2007 0.80
82 Neurocysticercal antigens stimulate chemokine secretion from human monocytes via an NF-kappaB-dependent pathway. Microbes Infect 2006 0.79
83 An evaluation of community assessment tools (CATs) in predicting use of clinical interventions and severe outcomes during the A(H1N1)pdm09 pandemic. PLoS One 2013 0.78
84 Serum bactericidal antibody response 1 year after meningococcal polysaccharide vaccination of patients with common variable immunodeficiency. Clin Vaccine Immunol 2010 0.78
85 The alveolar microenvironment of patients infected with human immunodeficiency virus does not modify alveolar macrophage interactions with Streptococcus pneumoniae. Clin Vaccine Immunol 2013 0.78
86 Proinflammatory activation of Toll-like receptor-2 during exposure of penicillin-resistant Streptococcus pneumoniae to beta-lactam antibiotics. J Antimicrob Chemother 2006 0.77
87 Adjunctive rifampicin to reduce early mortality from Staphylococcus aureus bacteraemia (ARREST): study protocol for a randomised controlled trial. Trials 2012 0.77
88 Correlation of group C meningococcal conjugate vaccine response with B- and T-lymphocyte activity. PLoS One 2012 0.77
89 The glycopeptide vancomycin does not enhance toll-like receptor 2 (TLR2) activation by Streptococcus pneumoniae. J Antimicrob Chemother 2004 0.77
90 Bacterial genomic detection within cerebrospinal fluid of patients with meningococcal disease is influenced by microbial and host characteristics. Clin Infect Dis 2011 0.77
91 Contact dependent suppression of CD4 T cell activation and proliferation by B cells activated through IgD cross-linking. Immunology 2014 0.75
92 The nonpathogenic commensal Neisseria: friends and foes in infectious disease. Curr Opin Infect Dis 2019 0.75
93 Using the NIHR Comprehensive Clinical Research Network for infectious diseases and microbiology research. J Infect 2012 0.75