PubRank

Axel Imhof

Author PubWeight™ 113.93‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites. Cell 2002 12.28
2 Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer. Nat Genet 2005 8.45
3 Retracted Histone methylation by the Drosophila epigenetic transcriptional regulator Ash1. Nature 2002 4.18
4 Identification of a specific inhibitor of the histone methyltransferase SU(VAR)3-9. Nat Chem Biol 2005 3.49
5 PTMs on H3 variants before chromatin assembly potentiate their final epigenetic state. Mol Cell 2006 3.20
6 hMOF histone acetyltransferase is required for histone H4 lysine 16 acetylation in mammalian cells. Mol Cell Biol 2005 2.69
7 Synergy between CD26/DPP-IV inhibition and G-CSF improves cardiac function after acute myocardial infarction. Cell Stem Cell 2009 2.61
8 PRMT6-mediated methylation of R2 in histone H3 antagonizes H3 K4 trimethylation. Genes Dev 2007 2.34
9 Replication stress interferes with histone recycling and predeposition marking of new histones. Mol Cell 2010 2.31
10 Localized H3K36 methylation states define histone H4K16 acetylation during transcriptional elongation in Drosophila. EMBO J 2007 2.19
11 Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4. Nature 2010 2.01
12 Activation of RNA polymerase I transcription by cockayne syndrome group B protein and histone methyltransferase G9a. Mol Cell 2007 1.96
13 The dMi-2 chromodomains are DNA binding modules important for ATP-dependent nucleosome mobilization. EMBO J 2002 1.91
14 OPA1 processing reconstituted in yeast depends on the subunit composition of the m-AAA protease in mitochondria. Mol Biol Cell 2007 1.87
15 Dynamics of adaptive microevolution of hypermutable Pseudomonas aeruginosa during chronic pulmonary infection in patients with cystic fibrosis. J Infect Dis 2009 1.87
16 HP1 binding to chromatin methylated at H3K9 is enhanced by auxiliary factors. Mol Cell Biol 2006 1.84
17 Connecting threads: epigenetics and metabolism. Cell 2012 1.75
18 Secretome protein enrichment identifies physiological BACE1 protease substrates in neurons. EMBO J 2012 1.61
19 The HP1alpha-CAF1-SetDB1-containing complex provides H3K9me1 for Suv39-mediated K9me3 in pericentric heterochromatin. EMBO Rep 2009 1.61
20 A pair of centromeric proteins mediates reproductive isolation in Drosophila species. Dev Cell 2013 1.59
21 Fast signals and slow marks: the dynamics of histone modifications. Trends Biochem Sci 2010 1.58
22 A combination of different mass spectroscopic techniques for the analysis of dynamic changes of histone modifications. Proteomics 2004 1.56
23 The prion curing agent guanidinium chloride specifically inhibits ATP hydrolysis by Hsp104. J Biol Chem 2003 1.52
24 H3 lysine 4 is acetylated at active gene promoters and is regulated by H3 lysine 4 methylation. PLoS Genet 2011 1.43
25 Establishment of histone modifications after chromatin assembly. Nucleic Acids Res 2009 1.36
26 A gamma-secretase-like intramembrane cleavage of TNFalpha by the GxGD aspartyl protease SPPL2b. Nat Cell Biol 2006 1.36
27 The N-terminus of Drosophila SU(VAR)3-9 mediates dimerization and regulates its methyltransferase activity. Biochemistry 2004 1.34
28 Regulated intramembrane proteolysis of the interleukin-1 receptor II by alpha-, beta-, and gamma-secretase. J Biol Chem 2007 1.27
29 Related B cell clones that populate the CSF and CNS of patients with multiple sclerosis produce CSF immunoglobulin. J Neuroimmunol 2011 1.27
30 ESC, ESCL and their roles in Polycomb Group mechanisms. Mech Dev 2008 1.23
31 Interaction of HP1 and Brg1/Brm with the globular domain of histone H3 is required for HP1-mediated repression. PLoS Genet 2009 1.19
32 Impairment of prostate cancer cell growth by a selective and reversible lysine-specific demethylase 1 inhibitor. Int J Cancer 2012 1.18
33 Df31 protein and snoRNAs maintain accessible higher-order structures of chromatin. Mol Cell 2012 1.17
34 Probing the conformation of the ISWI ATPase domain with genetically encoded photoreactive crosslinkers and mass spectrometry. Mol Cell Proteomics 2011 1.14
35 Stepwise evolution of essential centromere function in a Drosophila neogene. Science 2013 1.13
36 Cbp3-Cbp6 interacts with the yeast mitochondrial ribosomal tunnel exit and promotes cytochrome b synthesis and assembly. J Cell Biol 2011 1.12
37 Proteome analysis of mitochondrial outer membrane from Neurospora crassa. Proteomics 2006 1.12
38 Proteins at the polypeptide tunnel exit of the yeast mitochondrial ribosome. J Biol Chem 2010 1.11
39 Circadian acetylome reveals regulation of mitochondrial metabolic pathways. Proc Natl Acad Sci U S A 2013 1.11
40 Sequential establishment of marks on soluble histones H3 and H4. J Biol Chem 2011 1.07
41 The Drosophila G9a gene encodes a multi-catalytic histone methyltransferase required for normal development. Nucleic Acids Res 2006 1.06
42 The use of mass spectrometry for the analysis of histone modifications. Methods Enzymol 2004 1.04
43 Site-specific acetylation of ISWI by GCN5. BMC Mol Biol 2007 1.02
44 Stage-specific histone modification profiles reveal global transitions in the Xenopus embryonic epigenome. PLoS One 2011 1.01
45 Yersinia protein kinase YopO is activated by a novel G-actin binding process. J Biol Chem 2006 0.99
46 Phosphorylation of SU(VAR)3-9 by the chromosomal kinase JIL-1. PLoS One 2010 0.97
47 Monomethylation of lysine 20 on histone H4 facilitates chromatin maturation. Mol Cell Biol 2008 0.97
48 Clonal analysis of Inquilinus limosus isolates from six cystic fibrosis patients and specific serum antibody response. J Med Microbiol 2006 0.96
49 Identification of novel Drosophila centromere-associated proteins. Proteomics 2014 0.94
50 MSL2 combines sensor and effector functions in homeostatic control of the Drosophila dosage compensation machinery. Mol Cell 2012 0.93
51 Fine mapping of posttranslational modifications of the linker histone H1 from Drosophila melanogaster. PLoS One 2008 0.92
52 Developmental regulation of N-terminal H2B methylation in Drosophila melanogaster. Nucleic Acids Res 2011 0.92
53 Circadian control of fatty acid elongation by SIRT1 protein-mediated deacetylation of acetyl-coenzyme A synthetase 1. J Biol Chem 2014 0.89
54 Bioinformatic analysis of proteomics data. BMC Syst Biol 2014 0.87
55 The analysis of histone modifications. Biochim Biophys Acta 2006 0.87
56 DOT1A-dependent H3K76 methylation is required for replication regulation in Trypanosoma brucei. Nucleic Acids Res 2012 0.86
57 Biomarker discovery from body fluids using mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2006 0.86
58 Drosophila HP1c is regulated by an auto-regulatory feedback loop through its binding partner Woc. PLoS One 2009 0.85
59 Every methyl counts--epigenetic calculus. FEBS Lett 2010 0.84
60 The sounds of silence--histone deacetylation meets histone methylation. Genetica 2003 0.84
61 Remodeling of nuclear architecture by the thiodioxoxpiperazine metabolite chaetocin. Exp Cell Res 2010 0.84
62 Role of the AAA protease Yme1 in folding of proteins in the intermembrane space of mitochondria. Mol Biol Cell 2012 0.84
63 Characterization of the insertase for β-barrel proteins of the outer mitochondrial membrane. J Cell Biol 2012 0.83
64 Mouse cytomegalovirus egress protein pM50 interacts with cellular endophilin-A2. Cell Microbiol 2012 0.82
65 Analysis of histone modifications by mass spectrometry. Curr Protoc Protein Sci 2008 0.82
66 Epstein-Barr virus-mediated transformation of B cells induces global chromatin changes independent to the acquisition of proliferation. Nucleic Acids Res 2013 0.81
67 The RNA helicase Rm62 cooperates with SU(VAR)3-9 to re-silence active transcription in Drosophila melanogaster. PLoS One 2011 0.80
68 Myb-binding protein 1a (Mybbp1a) regulates levels and processing of pre-ribosomal RNA. J Biol Chem 2012 0.80
69 Proteomic screen in the simple metazoan Hydra identifies 14-3-3 binding proteins implicated in cellular metabolism, cytoskeletal organisation and Ca2+ signalling. BMC Cell Biol 2007 0.79
70 Cross-talk between type three secretion system and metabolism in Yersinia. J Biol Chem 2009 0.78
71 RNA-interference components are dispensable for transcriptional silencing of the drosophila bithorax-complex. PLoS One 2013 0.77
72 Reply to "Chaetocin is a nonspecific inhibitor of histone lysine methyltransferases". Nat Chem Biol 2013 0.76
73 Lipids join the post-genomic era. Genome Biol 2006 0.75
74 Inside front cover: In situ detection of histone variants and modifications in mouse brain using imaging mass spectrometry. Proteomics 2016 0.75
75 A Focus on Chromatin Proteomics. Proteomics 2016 0.75