Published in Mol Cell on August 17, 2007
Disorders of nucleotide excision repair: the genetic and molecular basis of heterogeneity. Nat Rev Genet (2009) 2.48
Nucleolus: the fascinating nuclear body. Histochem Cell Biol (2007) 1.87
Epigenetic mechanisms in mammals. Cell Mol Life Sci (2009) 1.82
The structure of NoRC-associated RNA is crucial for targeting the chromatin remodelling complex NoRC to the nucleolus. EMBO Rep (2008) 1.64
The chromatin remodelling complex NoRC safeguards genome stability by heterochromatin formation at telomeres and centromeres. EMBO Rep (2013) 1.55
Epigenetic principles and mechanisms underlying nervous system functions in health and disease. Prog Neurobiol (2008) 1.53
Nucleosomes are depleted at the VSG expression site transcribed by RNA polymerase I in African trypanosomes. Eukaryot Cell (2009) 1.52
Dual role for the methyltransferase G9a in the maintenance of beta-globin gene transcription in adult erythroid cells. Proc Natl Acad Sci U S A (2009) 1.44
The NoRC complex mediates the heterochromatin formation and stability of silent rRNA genes and centromeric repeats. EMBO J (2010) 1.40
The role of Cockayne Syndrome group B (CSB) protein in base excision repair and aging. Mech Ageing Dev (2008) 1.36
FACT facilitates chromatin transcription by RNA polymerases I and III. EMBO J (2009) 1.23
SET for life: biochemical activities and biological functions of SET domain-containing proteins. Trends Biochem Sci (2013) 1.22
G9a, a multipotent regulator of gene expression. Epigenetics (2012) 1.20
Dysregulation of RNA polymerase I transcription during disease. Biochim Biophys Acta (2012) 1.16
Enhanced expression of EHMT2 is involved in the proliferation of cancer cells through negative regulation of SIAH1. Neoplasia (2011) 1.15
CSB protein is (a direct target of HIF-1 and) a critical mediator of the hypoxic response. EMBO J (2008) 1.13
The chromatin remodeling complex NuRD establishes the poised state of rRNA genes characterized by bivalent histone modifications and altered nucleosome positions. Proc Natl Acad Sci U S A (2012) 1.13
Genetic syndromes caused by mutations in epigenetic genes. Hum Genet (2013) 1.11
Phosphorylation by casein kinase 2 facilitates rRNA gene transcription by promoting dissociation of TIF-IA from elongating RNA polymerase I. Mol Cell Biol (2008) 1.10
Nucleotide excision repair-initiating proteins bind to oxidative DNA lesions in vivo. J Cell Biol (2012) 1.09
The histone H3 methyltransferase G9A epigenetically activates the serine-glycine synthesis pathway to sustain cancer cell survival and proliferation. Cell Metab (2013) 1.09
Interaction of nucleolin with ribosomal RNA genes and its role in RNA polymerase I transcription. Nucleic Acids Res (2012) 1.05
A case study in cross-talk: the histone lysine methyltransferases G9a and GLP. Nucleic Acids Res (2010) 1.05
Structure, function and regulation of CSB: a multi-talented gymnast. Mech Ageing Dev (2013) 1.02
SET-domain bacterial effectors target heterochromatin protein 1 to activate host rDNA transcription. EMBO Rep (2013) 0.99
Blinded by the UV light: how the focus on transcription-coupled NER has distracted from understanding the mechanisms of Cockayne syndrome neurologic disease. DNA Repair (Amst) (2013) 0.99
Structure and function of ribosomal RNA gene chromatin. Biochem Soc Trans (2008) 0.98
Tethering of the conserved piggyBac transposase fusion protein CSB-PGBD3 to chromosomal AP-1 proteins regulates expression of nearby genes in humans. PLoS Genet (2012) 0.96
The sequence-specific transcription factor c-Jun targets Cockayne syndrome protein B to regulate transcription and chromatin structure. PLoS Genet (2014) 0.96
TFIIH is an elongation factor of RNA polymerase I. Nucleic Acids Res (2011) 0.95
Recognition of H3K9 methylation by GLP is required for efficient establishment of H3K9 methylation, rapid target gene repression, and mouse viability. Genes Dev (2015) 0.95
Nucleolar DNA: the host and the guests. Histochem Cell Biol (2016) 0.95
Human Cockayne syndrome B protein reciprocally communicates with mitochondrial proteins and promotes transcriptional elongation. Nucleic Acids Res (2012) 0.94
Evidence for premature aging due to oxidative stress in iPSCs from Cockayne syndrome. Hum Mol Genet (2012) 0.94
Basic mechanisms in RNA polymerase I transcription of the ribosomal RNA genes. Subcell Biochem (2013) 0.94
macroH2A1 histone variant represses rDNA transcription. Nucleic Acids Res (2013) 0.94
Structure and epigenetics of nucleoli in comparison with non-nucleolar compartments. J Histochem Cytochem (2009) 0.93
Mitochondrial deficiency in Cockayne syndrome. Mech Ageing Dev (2013) 0.92
Reciprocally regulated chromatin association of Cockayne syndrome protein B and p53 protein. J Biol Chem (2011) 0.91
Interaction between the Cockayne syndrome B and p53 proteins: implications for aging. Aging (Albany NY) (2012) 0.89
The chromatin remodelling complex B-WICH changes the chromatin structure and recruits histone acetyl-transferases to active rRNA genes. PLoS One (2011) 0.89
SUV39h-independent association of HP1 beta with fibrillarin-positive nucleolar regions. Chromosoma (2009) 0.89
DNA sequence encoded repression of rRNA gene transcription in chromatin. Nucleic Acids Res (2010) 0.84
Multiple interaction partners for Cockayne syndrome proteins: implications for genome and transcriptome maintenance. Mech Ageing Dev (2013) 0.83
The cockayne syndrome B protein is essential for neuronal differentiation and neuritogenesis. Cell Death Dis (2014) 0.83
The level and distribution pattern of HP1β in the embryonic brain correspond to those of H3K9me1/me2 but not of H3K9me3. Histochem Cell Biol (2016) 0.82
Angiogenin stimulates ribosomal RNA transcription by epigenetic activation of the ribosomal DNA promoter. J Cell Physiol (2014) 0.82
HP1β-dependent recruitment of UBF1 to irradiated chromatin occurs simultaneously with CPDs. Epigenetics Chromatin (2014) 0.81
Cockayne syndrome group B protein regulates DNA double-strand break repair and checkpoint activation. EMBO J (2015) 0.81
The CSB repair factor is overexpressed in cancer cells, increases apoptotic resistance, and promotes tumor growth. DNA Repair (Amst) (2013) 0.80
Nuclear microbiology--bacterial assault on the nucleolus. EMBO Rep (2013) 0.79
Valosin-containing Protein (VCP)/p97 Segregase Mediates Proteolytic Processing of Cockayne Syndrome Group B (CSB) in Damaged Chromatin. J Biol Chem (2016) 0.79
Chromatin-specific regulation of mammalian rDNA transcription by clustered TTF-I binding sites. PLoS Genet (2013) 0.79
Histone demethylase PHF8 promotes epithelial to mesenchymal transition and breast tumorigenesis. Nucleic Acids Res (2016) 0.79
The chromatin remodeling factor CSB recruits histone acetyltransferase PCAF to rRNA gene promoters in active state for transcription initiation. PLoS One (2013) 0.78
Cockayne syndrome protein A is a transcription factor of RNA polymerase I and stimulates ribosomal biogenesis and growth. Cell Cycle (2014) 0.78
Chromatin association and regulation of rDNA transcription by the Ras-family protein RasL11a. EMBO J (2010) 0.78
Identification of Novel Proteins Co-Purifying with Cockayne Syndrome Group B (CSB) Reveals Potential Roles for CSB in RNA Metabolism and Chromatin Dynamics. PLoS One (2015) 0.78
Canonical Wnt signalling regulates nuclear export of Setdb1 during skeletal muscle terminal differentiation. Cell Discov (2016) 0.76
The WSTF-ISWI chromatin remodeling complex transiently associates with the human inactive X chromosome during late S-phase prior to BRCA1 and γ-H2AX. PLoS One (2012) 0.76
Localized movement and morphology of UBF1-positive nucleolar regions are changed by γ-irradiation in G2 phase of the cell cycle. Nucleus (2015) 0.76
Epigenetics and chromatin plasticity in embryonic stem cells. World J Stem Cells (2013) 0.76
A Role for Widely Interspaced Zinc Finger (WIZ) in Retention of the G9a Methyltransferase on Chromatin. J Biol Chem (2015) 0.76
Transcription factors that influence RNA polymerases I and II: To what extent is mechanism of action conserved? Biochim Biophys Acta (2016) 0.75
Analysis of histone modifications at human ribosomal DNA in liver cancer cell. Sci Rep (2015) 0.75
The Epigenetic Pathways to Ribosomal DNA Silencing. Microbiol Mol Biol Rev (2016) 0.75
Nucleolar Reorganization Upon Site-Specific Double-Strand Break Induction: DNA Repair and Epigenetics of Ribosomal Genes. J Histochem Cytochem (2016) 0.75
UV-induced proteolysis of RNA polymerase II is mediated by VCP/p97 segregase and timely orchestration by Cockayne syndrome B protein. Oncotarget (2016) 0.75
Wiz binds active promoters and CTCF-binding sites and is required for normal behaviour in the mouse. Elife (2016) 0.75
CSB ablation induced apoptosis is mediated by increased endoplasmic reticulum stress response. PLoS One (2017) 0.75
The Nucleolus: In Genome Maintenance and Repair. Int J Mol Sci (2017) 0.75
Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites. Cell (2002) 12.28
Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer. Nat Genet (2005) 8.45
A kinetic framework for a mammalian RNA polymerase in vivo. Science (2002) 4.42
Retracted Histone methylation by the Drosophila epigenetic transcriptional regulator Ash1. Nature (2002) 4.18
c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription. Nat Cell Biol (2005) 3.79
The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription. Nat Genet (2002) 3.58
Identification of a specific inhibitor of the histone methyltransferase SU(VAR)3-9. Nat Chem Biol (2005) 3.49
The epigenetics of rRNA genes: from molecular to chromosome biology. Annu Rev Cell Dev Biol (2008) 3.42
PTMs on H3 variants before chromatin assembly potentiate their final epigenetic state. Mol Cell (2006) 3.20
Interaction of noncoding RNA with the rDNA promoter mediates recruitment of DNMT3b and silencing of rRNA genes. Genes Dev (2010) 2.96
mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability. Genes Dev (2004) 2.96
Intergenic transcripts regulate the epigenetic state of rRNA genes. Mol Cell (2006) 2.89
hMOF histone acetyltransferase is required for histone H4 lysine 16 acetylation in mammalian cells. Mol Cell Biol (2005) 2.69
Synergy between CD26/DPP-IV inhibition and G-CSF improves cardiac function after acute myocardial infarction. Cell Stem Cell (2009) 2.61
Nuclear actin and myosin I are required for RNA polymerase I transcription. Nat Cell Biol (2004) 2.49
Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription. Genes Dev (2006) 2.47
Genetic inactivation of the transcription factor TIF-IA leads to nucleolar disruption, cell cycle arrest, and p53-mediated apoptosis. Mol Cell (2005) 2.46
The RNA polymerase I transcription machinery: an emerging target for the treatment of cancer. Annu Rev Pharmacol Toxicol (2010) 2.45
The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription. EMBO J (2002) 2.36
PRMT6-mediated methylation of R2 in histone H3 antagonizes H3 K4 trimethylation. Genes Dev (2007) 2.34
Replication stress interferes with histone recycling and predeposition marking of new histones. Mol Cell (2010) 2.31
Localized H3K36 methylation states define histone H4K16 acetylation during transcriptional elongation in Drosophila. EMBO J (2007) 2.19
The nucleolus as a stress sensor: JNK2 inactivates the transcription factor TIF-IA and down-regulates rRNA synthesis. Genes Dev (2005) 2.13
Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4. Nature (2010) 2.01
ERK-dependent phosphorylation of the transcription initiation factor TIF-IA is required for RNA polymerase I transcription and cell growth. Mol Cell (2003) 1.98
TAF12 recruits Gadd45a and the nucleotide excision repair complex to the promoter of rRNA genes leading to active DNA demethylation. Mol Cell (2009) 1.97
CSB is a component of RNA pol I transcription. Mol Cell (2002) 1.93
PHF8 activates transcription of rRNA genes through H3K4me3 binding and H3K9me1/2 demethylation. Nat Struct Mol Biol (2010) 1.91
The dMi-2 chromodomains are DNA binding modules important for ATP-dependent nucleosome mobilization. EMBO J (2002) 1.91
Cellular stress and nucleolar function. Cell Cycle (2005) 1.88
OPA1 processing reconstituted in yeast depends on the subunit composition of the m-AAA protease in mitochondria. Mol Biol Cell (2007) 1.87
Dynamics of adaptive microevolution of hypermutable Pseudomonas aeruginosa during chronic pulmonary infection in patients with cystic fibrosis. J Infect Dis (2009) 1.87
HP1 binding to chromatin methylated at H3K9 is enhanced by auxiliary factors. Mol Cell Biol (2006) 1.84
Identification of novel functional TBP-binding sites and general factor repertoires. EMBO J (2007) 1.77
Connecting threads: epigenetics and metabolism. Cell (2012) 1.75
The PHD finger/bromodomain of NoRC interacts with acetylated histone H4K16 and is sufficient for rDNA silencing. Curr Biol (2005) 1.75
Epigenetic mechanism of rRNA gene silencing: temporal order of NoRC-mediated histone modification, chromatin remodeling, and DNA methylation. Mol Cell Biol (2005) 1.66
The structure of NoRC-associated RNA is crucial for targeting the chromatin remodelling complex NoRC to the nucleolus. EMBO Rep (2008) 1.64
Nuclear myosin I acts in concert with polymeric actin to drive RNA polymerase I transcription. Genes Dev (2008) 1.63
Secretome protein enrichment identifies physiological BACE1 protease substrates in neurons. EMBO J (2012) 1.61
The HP1alpha-CAF1-SetDB1-containing complex provides H3K9me1 for Suv39-mediated K9me3 in pericentric heterochromatin. EMBO Rep (2009) 1.61
A pair of centromeric proteins mediates reproductive isolation in Drosophila species. Dev Cell (2013) 1.59
The chromatin remodelling complex WSTF-SNF2h interacts with nuclear myosin 1 and has a role in RNA polymerase I transcription. EMBO Rep (2006) 1.59
Fast signals and slow marks: the dynamics of histone modifications. Trends Biochem Sci (2010) 1.58
A combination of different mass spectroscopic techniques for the analysis of dynamic changes of histone modifications. Proteomics (2004) 1.56
The chromatin remodelling complex NoRC safeguards genome stability by heterochromatin formation at telomeres and centromeres. EMBO Rep (2013) 1.55
The prion curing agent guanidinium chloride specifically inhibits ATP hydrolysis by Hsp104. J Biol Chem (2003) 1.52
Multiple interactions between RNA polymerase I, TIF-IA and TAF(I) subunits regulate preinitiation complex assembly at the ribosomal gene promoter. EMBO Rep (2002) 1.48
Modulation of RNA polymerase assembly dynamics in transcriptional regulation. Mol Cell (2008) 1.47
TFIIH plays an essential role in RNA polymerase I transcription. Cell (2002) 1.43
H3 lysine 4 is acetylated at active gene promoters and is regulated by H3 lysine 4 methylation. PLoS Genet (2011) 1.43
Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase 1 (Dnmt1) deficient cells. Nucleic Acids Res (2007) 1.42
Repression of RNA polymerase I upon stress is caused by inhibition of RNA-dependent deacetylation of PAF53 by SIRT7. Mol Cell (2013) 1.41
The alternating access transport mechanism in LacY. J Membr Biol (2010) 1.41
The NoRC complex mediates the heterochromatin formation and stability of silent rRNA genes and centromeric repeats. EMBO J (2010) 1.40
AMP-activated protein kinase adapts rRNA synthesis to cellular energy supply. Proc Natl Acad Sci U S A (2009) 1.40
NoRC-dependent nucleosome positioning silences rRNA genes. EMBO J (2006) 1.39
Establishment of histone modifications after chromatin assembly. Nucleic Acids Res (2009) 1.36
A gamma-secretase-like intramembrane cleavage of TNFalpha by the GxGD aspartyl protease SPPL2b. Nat Cell Biol (2006) 1.36
NuRD blocks reprogramming of mouse somatic cells into pluripotent stem cells. Stem Cells (2013) 1.35
The N-terminus of Drosophila SU(VAR)3-9 mediates dimerization and regulates its methyltransferase activity. Biochemistry (2004) 1.34
The chromatin remodeling complex NoRC controls replication timing of rRNA genes. EMBO J (2004) 1.34
Reversible acetylation of the chromatin remodelling complex NoRC is required for non-coding RNA-dependent silencing. Nat Cell Biol (2009) 1.30
Regulated intramembrane proteolysis of the interleukin-1 receptor II by alpha-, beta-, and gamma-secretase. J Biol Chem (2007) 1.27
Related B cell clones that populate the CSF and CNS of patients with multiple sclerosis produce CSF immunoglobulin. J Neuroimmunol (2011) 1.27
ESC, ESCL and their roles in Polycomb Group mechanisms. Mech Dev (2008) 1.23
Nucleolar disruption in dopaminergic neurons leads to oxidative damage and parkinsonism through repression of mammalian target of rapamycin signaling. J Neurosci (2011) 1.20
TR surfaces and conformations required to bind nuclear receptor corepressor. Mol Endocrinol (2002) 1.20
Interaction of HP1 and Brg1/Brm with the globular domain of histone H3 is required for HP1-mediated repression. PLoS Genet (2009) 1.19
Impairment of prostate cancer cell growth by a selective and reversible lysine-specific demethylase 1 inhibitor. Int J Cancer (2012) 1.18
Df31 protein and snoRNAs maintain accessible higher-order structures of chromatin. Mol Cell (2012) 1.17
The chromatin remodeling complex NoRC and TTF-I cooperate in the regulation of the mammalian rRNA genes in vivo. Nucleic Acids Res (2004) 1.16
Recruitment of the nucleolar remodeling complex NoRC establishes ribosomal DNA silencing in chromatin. Mol Cell Biol (2004) 1.15
The nucleolus—guardian of cellular homeostasis and genome integrity. Chromosoma (2013) 1.14
Probing the conformation of the ISWI ATPase domain with genetically encoded photoreactive crosslinkers and mass spectrometry. Mol Cell Proteomics (2011) 1.14
Stepwise evolution of essential centromere function in a Drosophila neogene. Science (2013) 1.13
The chromatin remodeling complex NuRD establishes the poised state of rRNA genes characterized by bivalent histone modifications and altered nucleosome positions. Proc Natl Acad Sci U S A (2012) 1.13
Cbp3-Cbp6 interacts with the yeast mitochondrial ribosomal tunnel exit and promotes cytochrome b synthesis and assembly. J Cell Biol (2011) 1.12
Activation of an endogenous suicide response after perturbation of rRNA synthesis leads to neurodegeneration in mice. J Neurosci (2008) 1.12
Proteome analysis of mitochondrial outer membrane from Neurospora crassa. Proteomics (2006) 1.12
Proteins at the polypeptide tunnel exit of the yeast mitochondrial ribosome. J Biol Chem (2010) 1.11
Circadian acetylome reveals regulation of mitochondrial metabolic pathways. Proc Natl Acad Sci U S A (2013) 1.11
Phosphorylation by casein kinase 2 facilitates rRNA gene transcription by promoting dissociation of TIF-IA from elongating RNA polymerase I. Mol Cell Biol (2008) 1.10
Sequential establishment of marks on soluble histones H3 and H4. J Biol Chem (2011) 1.07
The Drosophila G9a gene encodes a multi-catalytic histone methyltransferase required for normal development. Nucleic Acids Res (2006) 1.06
Intergenic transcripts originating from a subclass of ribosomal DNA repeats silence ribosomal RNA genes in trans. EMBO Rep (2009) 1.05
Proximity of transmembrane domains 1 and 3 of the gamma-aminobutyric acid transporter GAT-1 inferred from paired cysteine mutagenesis. J Biol Chem (2005) 1.04
The use of mass spectrometry for the analysis of histone modifications. Methods Enzymol (2004) 1.04
Site-specific acetylation of ISWI by GCN5. BMC Mol Biol (2007) 1.02
Human Cdc14B promotes progression through mitosis by dephosphorylating Cdc25 and regulating Cdk1/cyclin B activity. PLoS One (2011) 1.01
Clogging the periplasmic pathway in LacY. Biochemistry (2009) 1.01
Stage-specific histone modification profiles reveal global transitions in the Xenopus embryonic epigenome. PLoS One (2011) 1.01
Yersinia protein kinase YopO is activated by a novel G-actin binding process. J Biol Chem (2006) 0.99
Evidence for an intermediate conformational state of LacY. Proc Natl Acad Sci U S A (2012) 0.97