Published in Exp Dermatol on April 13, 2011
Cysteine-rich protein 61 (CCN1) domain-specific stimulation of matrix metalloproteinase-1 expression through αVβ3 integrin in human skin fibroblasts. J Biol Chem (2013) 0.93
The controversial role of retinoic acid in fibrotic diseases: analysis of involved signaling pathways. Int J Mol Sci (2012) 0.82
Transforming growth factor-β-sphingosine kinase 1/S1P signaling upregulates microRNA-21 to promote fibrosis in renal tubular epithelial cells. Exp Biol Med (Maywood) (2015) 0.79
Oxidant exposure induces cysteine-rich protein 61 (CCN1) via c-Jun/AP-1 to reduce collagen expression in human dermal fibroblasts. PLoS One (2014) 0.75
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo. Int J Cosmet Sci (2016) 0.75
Cell-based assay system for high-throughput screening of anti-photo-aging agents in fibroblast transfectants. Cytotechnology (2015) 0.75
All in the CCN family: essential matricellular signaling modulators emerge from the bunker. J Cell Sci (2006) 5.18
CCN proteins: multifunctional signalling regulators. Lancet (2004) 4.88
Pathophysiology of premature skin aging induced by ultraviolet light. N Engl J Med (1997) 4.57
The CCN family of angiogenic regulators: the integrin connection. Exp Cell Res (1999) 3.90
The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing. Nat Cell Biol (2010) 3.29
The CCN family: a new stimulus package. J Endocrinol (2003) 3.16
Restoration of collagen formation in photodamaged human skin by tretinoin (retinoic acid) N Engl J Med (1993) 3.06
Decreased collagen production in chronologically aged skin: roles of age-dependent alteration in fibroblast function and defective mechanical stimulation. Am J Pathol (2006) 2.10
Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin. J Invest Dermatol (2000) 1.97
Collagen fragmentation promotes oxidative stress and elevates matrix metalloproteinase-1 in fibroblasts in aged human skin. Am J Pathol (2008) 1.93
Looking older: fibroblast collapse and therapeutic implications. Arch Dermatol (2008) 1.86
Matrix-degrading metalloproteinases in photoaging. J Investig Dermatol Symp Proc (2009) 1.72
Molecular mechanisms of retinoid actions in skin. FASEB J (1996) 1.69
Solar ultraviolet irradiation reduces collagen in photoaged human skin by blocking transforming growth factor-beta type II receptor/Smad signaling. Am J Pathol (2004) 1.61
Reduced type I and type III procollagens in photodamaged adult human skin. J Invest Dermatol (1995) 1.60
Ultraviolet irradiation of human skin causes functional vitamin A deficiency, preventable by all-trans retinoic acid pre-treatment. Nat Med (1999) 1.56
Retinoic acid inhibits induction of c-Jun protein by ultraviolet radiation that occurs subsequent to activation of mitogen-activated protein kinase pathways in human skin in vivo. J Clin Invest (1998) 1.55
c-Jun-dependent inhibition of cutaneous procollagen transcription following ultraviolet irradiation is reversed by all-trans retinoic acid. J Clin Invest (2000) 1.50
Molecular mechanisms of photoaging and its prevention by retinoic acid: ultraviolet irradiation induces MAP kinase signal transduction cascades that induce Ap-1-regulated matrix metalloproteinases that degrade human skin in vivo. J Investig Dermatol Symp Proc (1998) 1.43
Matricellular protein CCN1 activates a proinflammatory genetic program in murine macrophages. J Immunol (2010) 1.42
Current use and future potential role of retinoids in dermatology. Drugs (1997) 1.35
Reduced fibroblast interaction with intact collagen as a mechanism for depressed collagen synthesis in photodamaged skin. J Invest Dermatol (2004) 1.31
Ultraviolet irradiation alters transforming growth factor beta/smad pathway in human skin in vivo. J Invest Dermatol (2002) 1.26
Collagen degradation in aged/photodamaged skin in vivo and after exposure to matrix metalloproteinase-1 in vitro. J Invest Dermatol (2003) 1.25
Ultraviolet irradiation blocks cellular responses to transforming growth factor-beta by down-regulating its type-II receptor and inducing Smad7. J Biol Chem (2001) 1.24
Elevated cysteine-rich 61 mediates aberrant collagen homeostasis in chronologically aged and photoaged human skin. Am J Pathol (2006) 1.20
Connective tissue growth factor: expression in human skin in vivo and inhibition by ultraviolet irradiation. J Invest Dermatol (2002) 1.16
Ultraviolet irradiation induces CYR61/CCN1, a mediator of collagen homeostasis, through activation of transcription factor AP-1 in human skin fibroblasts. J Invest Dermatol (2010) 1.08
Immunological identification and functional quantitation of retinoic acid and retinoid X receptor proteins in human skin. J Biol Chem (1994) 1.00
Expression and regulation of Cyr61 in human breast cancer cell lines. Oncogene (2002) 0.97
Differential regulation of retinoic acid receptors and binding proteins in human skin. J Invest Dermatol (1992) 0.96
Protective effect of pomegranate-derived products on UVB-mediated damage in human reconstituted skin. Exp Dermatol (2009) 0.95
Reconstituted skin in culture: a simple method with optimal differentiation. Differentiation (1990) 0.95
Keratinocyte-conditioned media regulate collagen expression in dermal fibroblasts. J Invest Dermatol (2008) 0.91
Photoaging and topical tretinoin: therapy, pathogenesis, and prevention. Arch Dermatol (1997) 0.89
Investigation of keratinocyte regulation of collagen I synthesis by dermal fibroblasts in a simple in vitro model. Br J Dermatol (2006) 0.88
Long-term treatment of photoaged human skin with topical retinoic acid improves epidermal cell atypia and thickens the collagen band in papillary dermis. J Am Acad Dermatol (2005) 0.88
Keratinocytes inhibit expression of connective tissue growth factor in fibroblasts in vitro by an interleukin-1alpha-dependent mechanism. J Invest Dermatol (2002) 0.87
Expression of CRABP-I and -II in human epidermal cells. Alteration of relative protein amounts is linked to the state of differentiation. Biochem J (1992) 0.86
Latent and active transforming growth factor beta1 released from genetically modified keratinocytes modulates extracellular matrix expression by dermal fibroblasts in a coculture system. J Invest Dermatol (2002) 0.84
Retinoic acid receptors and binding proteins in human skin. J Invest Dermatol (1992) 0.84
Photoprotective effect of a water-soluble extract of Rosmarinus officinalis L. against UV-induced matrix metalloproteinase-1 in human dermal fibroblasts and reconstructed skin. Eur J Dermatol (2008) 0.79
Keratins 2 and 4/13 in reconstituted human skin are reciprocally regulated by retinoids binding to nuclear receptor RARalpha. Exp Dermatol (2010) 0.78
Keratinocyte-specific retinoid regulation of human cellular retinoic acid binding protein-II (hCRABPII) gene promoter requires an evolutionarily conserved DR1 retinoic acid-responsive element. J Invest Dermatol (1998) 0.78
Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways. Nat Genet (2009) 9.45
Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene. Am J Hum Genet (2006) 4.22
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. Nat Genet (2012) 4.13
Mechanisms of photoaging and chronological skin aging. Arch Dermatol (2002) 3.43
Genome-wide association analysis identifies three psoriasis susceptibility loci. Nat Genet (2010) 2.76
Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2. Nat Genet (2010) 2.66
UV-light-induced signal cascades and skin aging. Ageing Res Rev (2002) 2.34
Polymorphisms of the IL12B and IL23R genes are associated with psoriasis. J Invest Dermatol (2008) 2.20
CYP2C19 polymorphisms and antiplatelet effects of clopidogrel in acute ischemic stroke in China. Stroke (2013) 2.12
Decreased collagen production in chronologically aged skin: roles of age-dependent alteration in fibroblast function and defective mechanical stimulation. Am J Pathol (2006) 2.10
Global gene expression analysis reveals evidence for decreased lipid biosynthesis and increased innate immunity in uninvolved psoriatic skin. J Invest Dermatol (2009) 2.06
Genetic deletion of AT1a receptors attenuates intracellular accumulation of ANG II in the kidney of AT1a receptor-deficient mice. Am J Physiol Renal Physiol (2007) 1.99
Reduced expression of connective tissue growth factor (CTGF/CCN2) mediates collagen loss in chronologically aged human skin. J Invest Dermatol (2009) 1.93
Collagen fragmentation promotes oxidative stress and elevates matrix metalloproteinase-1 in fibroblasts in aged human skin. Am J Pathol (2008) 1.93
Looking older: fibroblast collapse and therapeutic implications. Arch Dermatol (2008) 1.86
Connective tissue remodeling induced by carbon dioxide laser resurfacing of photodamaged human skin. Arch Dermatol (2004) 1.85
Meta-analysis confirms the LCE3C_LCE3B deletion as a risk factor for psoriasis in several ethnic groups and finds interaction with HLA-Cw6. J Invest Dermatol (2010) 1.82
IL-1F5, -F6, -F8, and -F9: a novel IL-1 family signaling system that is active in psoriasis and promotes keratinocyte antimicrobial peptide expression. J Immunol (2011) 1.80
Molecular dissection of psoriasis: integrating genetics and biology. J Invest Dermatol (2009) 1.79
Matrix-degrading metalloproteinases in photoaging. J Investig Dermatol Symp Proc (2009) 1.72
In vivo stimulation of de novo collagen production caused by cross-linked hyaluronic acid dermal filler injections in photodamaged human skin. Arch Dermatol (2007) 1.69
Nestin is required for the proper self-renewal of neural stem cells. Stem Cells (2010) 1.62
Solar ultraviolet irradiation reduces collagen in photoaged human skin by blocking transforming growth factor-beta type II receptor/Smad signaling. Am J Pathol (2004) 1.61
Assessment of the psoriatic transcriptome in a large sample: additional regulated genes and comparisons with in vitro models. J Invest Dermatol (2010) 1.61
Effect of increased pigmentation on the antifibrotic response of human skin to UV-A1 phototherapy. Arch Dermatol (2008) 1.59
Treatment of acne vulgaris with a pulsed dye laser: a randomized controlled trial. JAMA (2004) 1.49
Retracted Downregulation of ADAM10 expression inhibits metastasis and invasiveness of human hepatocellular carcinoma HepG2 cells. Biomed Res Int (2013) 1.44
Transabdominal Preperitoneal (TAPP) Versus Totally Extraperitoneal (TEP) for Laparoscopic Hernia Repair: A Meta-Analysis. Surg Laparosc Endosc Percutan Tech (2015) 1.42
Genome-wide expression profiling of five mouse models identifies similarities and differences with human psoriasis. PLoS One (2011) 1.41
Matrix metalloproteinase-1 is the major collagenolytic enzyme responsible for collagen damage in UV-irradiated human skin. Photochem Photobiol (2003) 1.41
Overview of skin aging and photoaging. Dermatol Nurs (2008) 1.39
Receptor-type protein-tyrosine phosphatase-kappa regulates epidermal growth factor receptor function. J Biol Chem (2005) 1.35
Inflammation and extracellular matrix degradation mediated by activated transcription factors nuclear factor-kappaB and activator protein-1 in inflammatory acne lesions in vivo. Am J Pathol (2005) 1.35
Dissecting the psoriasis transcriptome: inflammatory- and cytokine-driven gene expression in lesions from 163 patients. BMC Genomics (2013) 1.32
Reduced fibroblast interaction with intact collagen as a mechanism for depressed collagen synthesis in photodamaged skin. J Invest Dermatol (2004) 1.31
Ultraviolet irradiation alters transforming growth factor beta/smad pathway in human skin in vivo. J Invest Dermatol (2002) 1.26
Collagen degradation in aged/photodamaged skin in vivo and after exposure to matrix metalloproteinase-1 in vitro. J Invest Dermatol (2003) 1.25
Oxidative inhibition of receptor-type protein-tyrosine phosphatase kappa by ultraviolet irradiation activates epidermal growth factor receptor in human keratinocytes. J Biol Chem (2006) 1.23
Elevated cysteine-rich 61 mediates aberrant collagen homeostasis in chronologically aged and photoaged human skin. Am J Pathol (2006) 1.20
AT1a receptor knockout in mice impairs urine concentration by reducing basal vasopressin levels and its receptor signaling proteins in the inner medulla. Kidney Int (2009) 1.17
Communication between host organism and cancer cells is transduced by systemic sphingosine kinase 1/sphingosine 1-phosphate signalling to regulate tumour metastasis. EMBO Mol Med (2012) 1.16
Isolation and culture of skin fibroblasts. Methods Mol Med (2005) 1.16
Connective tissue growth factor: expression in human skin in vivo and inhibition by ultraviolet irradiation. J Invest Dermatol (2002) 1.16
Retinoid-induced epidermal hyperplasia is mediated by epidermal growth factor receptor activation via specific induction of its ligands heparin-binding EGF and amphiregulin in human skin in vivo. J Invest Dermatol (2006) 1.14
Inhibition of type I procollagen production in photodamage: correlation between presence of high molecular weight collagen fragments and reduced procollagen synthesis. J Invest Dermatol (2002) 1.13
Epidermal growth factor receptor-dependent, NF-kappaB-independent activation of the phosphatidylinositol 3-kinase/Akt pathway inhibits ultraviolet irradiation-induced caspases-3, -8, and -9 in human keratinocytes. J Biol Chem (2003) 1.13
Topical N-acetyl cysteine and genistein prevent ultraviolet-light-induced signaling that leads to photoaging in human skin in vivo. J Invest Dermatol (2003) 1.12
Differential ErbB1 signaling in squamous cell versus basal cell carcinoma of the skin. Am J Pathol (2007) 1.11
TNFAIP3 gene polymorphisms are associated with response to TNF blockade in psoriasis. J Invest Dermatol (2011) 1.10
Evidence for altered Wnt signaling in psoriatic skin. J Invest Dermatol (2010) 1.08
Ultraviolet irradiation induces CYR61/CCN1, a mediator of collagen homeostasis, through activation of transcription factor AP-1 in human skin fibroblasts. J Invest Dermatol (2010) 1.08
Epidermal growth factor receptor is a critical mediator of ultraviolet B irradiation-induced signal transduction in immortalized human keratinocyte HaCaT cells. Am J Pathol (2006) 1.08
Ultraviolet irradiation induces Smad7 via induction of transcription factor AP-1 in human skin fibroblasts. J Biol Chem (2004) 1.07
Effect of smoking on aging of photoprotected skin: evidence gathered using a new photonumeric scale. Arch Dermatol (2007) 1.07
Meta-profiles of gene expression during aging: limited similarities between mouse and human and an unexpectedly decreased inflammatory signature. PLoS One (2012) 1.06
Elevated matrix metalloproteinases and collagen fragmentation in photodamaged human skin: impact of altered extracellular matrix microenvironment on dermal fibroblast function. J Invest Dermatol (2013) 1.06
Hedgehog signaling maintains hair follicle stem cell phenotype in young and aged human skin. Aging Cell (2009) 1.03
Analysis of long non-coding RNAs highlights tissue-specific expression patterns and epigenetic profiles in normal and psoriatic skin. Genome Biol (2015) 1.03
Enhancing structural support of the dermal microenvironment activates fibroblasts, endothelial cells, and keratinocytes in aged human skin in vivo. J Invest Dermatol (2012) 1.03
Glucagon receptor-mediated extracellular signal-regulated kinase 1/2 phosphorylation in rat mesangial cells: role of protein kinase A and phospholipase C. Hypertension (2006) 1.02
Induction of collagen by estradiol: difference between sun-protected and photodamaged human skin in vivo. Arch Dermatol (2008) 1.02