Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene.

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Published in Am J Hum Genet on March 31, 2006

Authors

Rajan P Nair1, Philip E Stuart, Ioana Nistor, Ravi Hiremagalore, Nicholas V C Chia, Stefan Jenisch, Michael Weichenthal, Gonçalo R Abecasis, Henry W Lim, Enno Christophers, John J Voorhees, James T Elder

Author Affiliations

1: Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI 48109-0932, USA.

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Antimicrobial psoriasin (S100A7) protects human skin from Escherichia coli infection. Nat Immunol (2004) 3.19

Strong association of the Y402H variant in complement factor H at 1q32 with susceptibility to age-related macular degeneration. Am J Hum Genet (2005) 3.19

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet (2013) 2.83

Genome-wide association analysis identifies three psoriasis susceptibility loci. Nat Genet (2010) 2.76

Efficient study designs for test of genetic association using sibship data and unrelated cases and controls. Am J Hum Genet (2006) 2.72

Increased prevalence of the metabolic syndrome in patients with moderate to severe psoriasis. Arch Dermatol Res (2006) 2.67

Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2. Nat Genet (2010) 2.66

Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion. Nat Genet (2012) 2.55

Dissecting the genetic complexity of the association between human leukocyte antigens and rheumatoid arthritis. Am J Hum Genet (2002) 2.47

Association analyses identify six new psoriasis susceptibility loci in the Chinese population. Nat Genet (2010) 2.41