| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Spinal glia and proinflammatory cytokines mediate mirror-image neuropathic pain in rats.
|
J Neurosci
|
2003
|
2.87
|
|
2
|
Infusion of pharmaceutical-grade natural human C-reactive protein is not proinflammatory in healthy adult human volunteers.
|
Circ Res
|
2013
|
2.26
|
|
3
|
Hypernociceptive role of cytokines and chemokines: targets for analgesic drug development?
|
Pharmacol Ther
|
2006
|
2.13
|
|
4
|
"Cytokine storm" in the phase I trial of monoclonal antibody TGN1412: better understanding the causes to improve preclinical testing of immunotherapeutics.
|
J Immunol
|
2007
|
2.11
|
|
5
|
Proinflammatory cytokines oppose opioid-induced acute and chronic analgesia.
|
Brain Behav Immun
|
2008
|
1.92
|
|
6
|
Crucial role of neutrophils in the development of mechanical inflammatory hypernociception.
|
J Leukoc Biol
|
2008
|
1.64
|
|
7
|
Cardiopulmonary resuscitation feedback improves the quality of chest compression provided by hospital health care professionals.
|
Am J Emerg Med
|
2010
|
1.58
|
|
8
|
The viral mimic, polyinosinic:polycytidylic acid, induces fever in rats via an interleukin-1-dependent mechanism.
|
Am J Physiol Regul Integr Comp Physiol
|
2004
|
1.38
|
|
9
|
Antinociceptive effects of interleukin-4, -10, and -13 on the writhing response in mice and zymosan-induced knee joint incapacitation in rats.
|
J Pharmacol Exp Ther
|
2003
|
1.30
|
|
10
|
Circulating interleukin-6 induces fever through a STAT3-linked activation of COX-2 in the brain.
|
Am J Physiol Regul Integr Comp Physiol
|
2006
|
1.20
|
|
11
|
Tumour necrosis factor-alpha, interleukin-1beta and interleukin-8 induce persistent mechanical nociceptor hypersensitivity.
|
Pain
|
2002
|
1.15
|
|
12
|
Safety of biologics, lessons learnt from TGN1412.
|
Curr Opin Biotechnol
|
2009
|
1.12
|
|
13
|
Peri-sciatic proinflammatory cytokines, reactive oxygen species, and complement induce mirror-image neuropathic pain in rats.
|
Pain
|
2004
|
1.11
|
|
14
|
Antihyperalgesic effect of pentoxifylline on experimental inflammatory pain.
|
Br J Pharmacol
|
2004
|
1.09
|
|
15
|
Interleukin-6 in combination with its soluble IL-6 receptor sensitises rat skin nociceptors to heat, in vivo.
|
Pain
|
2002
|
1.08
|
|
16
|
How predictive are in vitro assays for cytokine release syndrome in vivo? A comparison of methods reveals worrying differences in sensitivity and frequency of response.
|
Cytokine
|
2013
|
1.08
|
|
17
|
Cytokine-induced neutrophil chemoattractant 1 (CINC-1) mediates the sympathetic component of inflammatory mechanical hypersensitivitiy in rats.
|
Eur Cytokine Netw
|
2003
|
1.07
|
|
18
|
Interleukin-6 and leptin mediate lipopolysaccharide-induced fever and sickness behavior.
|
Physiol Behav
|
2006
|
1.07
|
|
19
|
Interleukin-6 mediates low-threshold mechanical allodynia induced by intrathecal HIV-1 envelope glycoprotein gp120.
|
Brain Behav Immun
|
2007
|
1.02
|
|
20
|
Antigen-induced inflammatory mechanical hypernociception in mice is mediated by IL-18.
|
Brain Behav Immun
|
2006
|
1.02
|
|
21
|
Enduring reversal of neuropathic pain by a single intrathecal injection of adenosine 2A receptor agonists: a novel therapy for neuropathic pain.
|
J Neurosci
|
2009
|
1.01
|
|
22
|
Genetic modifiers of abnormal organelle biogenesis in a Drosophila model of BLOC-1 deficiency.
|
Hum Mol Genet
|
2009
|
1.00
|
|
23
|
International validation of novel pyrogen tests based on human monocytoid cells.
|
J Immunol Methods
|
2005
|
0.99
|
|
24
|
Snake venom phospholipase A2s (Asp49 and Lys49) induce mechanical allodynia upon peri-sciatic administration: involvement of spinal cord glia, proinflammatory cytokines and nitric oxide.
|
Pain
|
2004
|
0.97
|
|
25
|
IL-1-driven endogenous IL-10 production protects against the systemic and local acute inflammatory response following intestinal reperfusion injury.
|
J Immunol
|
2003
|
0.97
|
|
26
|
Role of cytokines in mediating mechanical hypernociception in a model of delayed-type hypersensitivity in mice.
|
Eur J Pain
|
2008
|
0.97
|
|
27
|
Severity of the TGN1412 trial disaster cytokine storm correlated with IL-2 release.
|
Br J Clin Pharmacol
|
2013
|
0.96
|
|
28
|
Improved in vitro methods to predict the in vivo toxicity in man of therapeutic monoclonal antibodies including TGN1412.
|
J Immunol Methods
|
2009
|
0.95
|
|
29
|
Interleukin (IL)-6 and IL-1 beta act synergistically within the brain to induce sickness behavior and fever in rats.
|
Brain Behav Immun
|
2008
|
0.95
|
|
30
|
Nociceptive effect of subcutaneously injected interleukin-12 is mediated by endothelin (ET) acting on ETB receptors in rats.
|
J Pharmacol Exp Ther
|
2005
|
0.95
|
|
31
|
Circulating leptin mediates lipopolysaccharide-induced anorexia and fever in rats.
|
J Physiol
|
2004
|
0.94
|
|
32
|
TNF-alpha and IL-1beta mediate inflammatory hypernociception in mice triggered by B1 but not B2 kinin receptor.
|
Eur J Pharmacol
|
2007
|
0.93
|
|
33
|
Attenuated fever in rats during late pregnancy is linked to suppressed interleukin-6 production after localized inflammation with turpentine.
|
J Physiol
|
2007
|
0.92
|
|
34
|
Differences in the relative involvement of peripherally released interleukin (IL)-6, brain IL-1β and prostanoids in mediating lipopolysaccharide-induced fever and sickness behavior.
|
Psychoneuroendocrinology
|
2010
|
0.91
|
|
35
|
Comparative cell signalling activity of ultrapure recombinant chaperonin 60 proteins from prokaryotes and eukaryotes.
|
Immunology
|
2005
|
0.91
|
|
36
|
Differential regulation of type I and type II interleukin-1 receptors in focal brain inflammation.
|
Eur J Neurosci
|
2005
|
0.90
|
|
37
|
The critical role of leukotriene B4 in antigen-induced mechanical hyperalgesia in immunised rats.
|
Br J Pharmacol
|
2003
|
0.90
|
|
38
|
Release of plasmid DNA-encoding IL-10 from PLGA microparticles facilitates long-term reversal of neuropathic pain following a single intrathecal administration.
|
Pharm Res
|
2010
|
0.89
|
|
39
|
In vitro cytokine release assays for predicting cytokine release syndrome: the current state-of-the-science. Report of a European Medicines Agency Workshop.
|
Cytokine
|
2010
|
0.89
|
|
40
|
Selective contribution of interleukin-6 and leptin to brain inflammatory signals induced by systemic LPS injection in mice.
|
J Comp Neurol
|
2008
|
0.89
|
|
41
|
Effect of a BLT receptor antagonist in a model of severe ischemia and reperfusion injury in the rat.
|
Eur J Pharmacol
|
2002
|
0.88
|
|
42
|
Using a medical simulation center as an electronic health record usability laboratory.
|
J Am Med Inform Assoc
|
2013
|
0.87
|
|
43
|
Immune-to-brain signaling and central prostaglandin E2 synthesis in fasted rats with altered lipopolysaccharide-induced fever.
|
Am J Physiol Regul Integr Comp Physiol
|
2008
|
0.85
|
|
44
|
Counter-regulation of interleukin-1alpha (IL-1alpha) and IL-1 receptor antagonist in murine keratinocytes.
|
J Invest Dermatol
|
2005
|
0.85
|
|
45
|
Endothelial cells co-stimulate peripheral blood mononuclear cell responses to monoclonal antibody TGN1412 in culture.
|
Cytokine
|
2011
|
0.85
|
|
46
|
Streptococcus sanguis secretes CD14-binding proteins that stimulate cytokine synthesis: a clue to the pathogenesis of infective (bacterial) endocarditis?
|
Microb Pathog
|
2002
|
0.82
|
|
47
|
Monocyte activation test for pro-inflammatory and pyrogenic contaminants of parenteral drugs: test design and data analysis.
|
J Immunol Methods
|
2004
|
0.82
|
|
48
|
Comparison of novel methods for predicting the risk of pro-inflammatory clinical infusion reactions during monoclonal antibody therapy.
|
J Immunol Methods
|
2011
|
0.82
|
|
49
|
Highly homologous Mycobacterium tuberculosis chaperonin 60 proteins with differential CD14 dependencies stimulate cytokine production by human monocytes through cooperative activation of p38 and ERK1/2 mitogen-activated protein kinases.
|
Int Immunopharmacol
|
2006
|
0.82
|
|
50
|
A critical role for TNFalpha in the selective attachment of mononuclear leukocytes to angiotensin-II-stimulated arterioles.
|
Blood
|
2007
|
0.82
|
|
51
|
Antibody C region influences TGN1412-like functional activity in vitro.
|
J Immunol
|
2012
|
0.81
|
|
52
|
Isolation and characterization of pharmaceutical grade human pentraxins, serum amyloid P component and C-reactive protein, for clinical use.
|
J Immunol Methods
|
2012
|
0.81
|
|
53
|
Anti-nociceptive effect of thalidomide on zymosan-induced experimental articular incapacitation.
|
Eur J Pharmacol
|
2006
|
0.80
|
|
54
|
Leptin and interleukin-6 alter the function of mesolimbic dopamine neurons in a rodent model of prenatal inflammation.
|
Psychoneuroendocrinology
|
2011
|
0.79
|
|
55
|
Anorexia in a rat model of colitis: interaction of interleukin-1 and hypothalamic serotonin.
|
Brain Res
|
2002
|
0.77
|
|
56
|
Critical role for peripherally-derived interleukin-10 in mediating the thermoregulatory manifestations of fever and hypothermia in severe forms of lipopolysaccharide-induced inflammation.
|
Pflugers Arch
|
2013
|
0.76
|
|
57
|
Interleukin-10 modulates the synthesis of inflammatory mediators in the sensory circumventricular organs: implications for the regulation of fever and sickness behaviors.
|
J Neuroinflammation
|
2013
|
0.76
|
|
58
|
Role of IL-13 in a model of Strongyloides venezuelensis infection in rats.
|
Microbes Infect
|
2010
|
0.76
|
|
59
|
NPU-based image compositing in a distributed visualization system.
|
IEEE Trans Vis Comput Graph
|
2007
|
0.75
|