Published in J Biol Chem on April 14, 2011
Global metabolic inhibitors of sialyl- and fucosyltransferases remodel the glycome. Nat Chem Biol (2012) 1.70
An inhibitor of chondroitin sulfate proteoglycan synthesis promotes central nervous system remyelination. Nat Commun (2016) 1.40
Developing inhibitors of glycan processing enzymes as tools for enabling glycobiology. Nat Chem Biol (2012) 1.21
Galectin-1 triggers an immunoregulatory signature in Th cells functionally defined by IL-10 expression. J Immunol (2012) 1.09
Development of orally active inhibitors of protein and cellular fucosylation. Proc Natl Acad Sci U S A (2013) 1.00
Galectin-1 research in T cell immunity: past, present and future. Clin Immunol (2011) 0.98
Metabolic inhibition of galectin-1-binding carbohydrates accentuates antitumor immunity. J Invest Dermatol (2011) 0.96
Galectin-1 inhibits the viability, proliferation, and Th1 cytokine production of nonmalignant T cells in patients with leukemic cutaneous T-cell lymphoma. Blood (2012) 0.95
Fluorosugar chain termination agents as probes of the sequence specificity of a carbohydrate polymerase. J Am Chem Soc (2012) 0.90
Human fucosyltransferase 6 enables prostate cancer metastasis to bone. Br J Cancer (2013) 0.86
Systemic blockade of sialylation in mice with a global inhibitor of sialyltransferases. J Biol Chem (2014) 0.86
Metabolic inhibition of sialyl-Lewis X biosynthesis by 5-thiofucose remodels the cell surface and impairs selectin-mediated cell adhesion. J Biol Chem (2012) 0.85
Galectins and their ligands: negative regulators of anti-tumor immunity. Glycoconj J (2012) 0.83
Interfering with UDP-GlcNAc metabolism and heparan sulfate expression using a sugar analogue reduces angiogenesis. ACS Chem Biol (2013) 0.80
Metabolic oligosaccharide engineering: implications for selectin-mediated adhesion and leukocyte extravasation. Ann Biomed Eng (2011) 0.79
A common sugar-nucleotide-mediated mechanism of inhibition of (glycosamino)glycan biosynthesis, as evidenced by 6F-GalNAc (Ac3). FASEB J (2015) 0.78
Leveraging fluorinated glucosamine action to boost antitumor immunity. Curr Opin Immunol (2012) 0.78
Melanoma Cell Galectin-1 Ligands Functionally Correlate with Malignant Potential. J Invest Dermatol (2015) 0.78
Synthesis of N-acetyl Glucosamine Analogs as Inhibitors for Hyaluronan Biosynthesis. J Carbohydr Chem (2013) 0.77
Golgi self-correction generates bioequivalent glycans to preserve cellular homeostasis. Elife (2016) 0.76
2-Fluoro-L-Fucose Is a Metabolically Incorporated Inhibitor of Plant Cell Wall Polysaccharide Fucosylation. PLoS One (2015) 0.76
Base-modified UDP-sugars reduce cell surface levels of P-selectin glycoprotein 1 (PSGL-1) on IL-1β-stimulated human monocytes. Glycobiology (2016) 0.76
Synthesis and in vitro cytotoxicity of acetylated 3-fluoro, 4-fluoro and 3,4-difluoro analogs of D-glucosamine and D-galactosamine. Beilstein J Org Chem (2016) 0.75
T-lymphocyte homing: an underappreciated yet critical hurdle for successful cancer immunotherapy. Lab Invest (2017) 0.75
Using CRISPR-Cas9 to quantify the contributions of O-glycans, N-glycans and Glycosphingolipids to human leukocyte-endothelium adhesion. Sci Rep (2016) 0.75
Glycoamino Acid Analogues of the Thomsen-Friedenreich Tumor-Associated Carbohydrate Antigen: Synthesis and Evaluation of Novel Antiproliferative Factor Glycopeptides. ACS Omega (2017) 0.75
A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics (2003) 82.89
Expression monitoring by hybridization to high-density oligonucleotide arrays. Nat Biotechnol (1996) 72.84
Controlling the false discovery rate in behavior genetics research. Behav Brain Res (2001) 21.82
Glycans in cancer and inflammation--potential for therapeutics and diagnostics. Nat Rev Drug Discov (2005) 6.14
Complex N-glycan number and degree of branching cooperate to regulate cell proliferation and differentiation. Cell (2007) 4.85
GlycoWorkbench: a tool for the computer-assisted annotation of mass spectra of glycans. J Proteome Res (2008) 3.85
Turning 'sweet' on immunity: galectin-glycan interactions in immune tolerance and inflammation. Nat Rev Immunol (2009) 3.22
Selectins in T-cell recruitment to non-lymphoid tissues and sites of inflammation. Nat Rev Immunol (2004) 3.04
Mammalian glycosylation in immunity. Nat Rev Immunol (2008) 2.74
The intersections between O-GlcNAcylation and phosphorylation: implications for multiple signaling pathways. J Cell Sci (2010) 2.22
A map of 75 human ribosomal protein genes. Genome Res (1998) 2.15
CD44 is a major E-selectin ligand on human hematopoietic progenitor cells. J Cell Biol (2001) 2.07
Galectins: regulators of acute and chronic inflammation. Ann N Y Acad Sci (2010) 1.83
Targeting selectins and selectin ligands in inflammation and cancer. Expert Opin Ther Targets (2007) 1.82
Glycomic profiling of cells and tissues by mass spectrometry: fingerprinting and sequencing methodologies. Methods Enzymol (2006) 1.82
Rolling of human bone-metastatic prostate tumor cells on human bone marrow endothelium under shear flow is mediated by E-selectin. Cancer Res (2004) 1.44
Prevention of leukocyte migration to inflamed skin with a novel fluorosugar modifier of cutaneous lymphocyte-associated antigen. J Clin Invest (2003) 1.43
Alpha 1,3 fucosyltransferases are master regulators of prostate cancer cell trafficking. Proc Natl Acad Sci U S A (2009) 1.40
Identification of leukocyte E-selectin ligands, P-selectin glycoprotein ligand-1 and E-selectin ligand-1, on human metastatic prostate tumor cells. Cancer Res (2005) 1.31
A distinct glycoform of CD44 is an L-selectin ligand on human hematopoietic cells. Proc Natl Acad Sci U S A (2000) 1.25
Conveying glycan information into T-cell homeostatic programs: a challenging role for galectin-1 in inflammatory and tumor microenvironments. Immunol Rev (2009) 1.24
Direct determination of the substrate specificity of the alpha-active site in heterodimeric beta-hexosaminidase A. Biochemistry (1996) 1.23
Glycosylation-dependent inhibition of cutaneous lymphocyte-associated antigen expression: implications in modulating lymphocyte migration to skin. Blood (2002) 1.16
A disaccharide precursor of sialyl Lewis X inhibits metastatic potential of tumor cells. Cancer Res (2003) 1.16
The eukaryotic UDP-N-acetylglucosamine pyrophosphorylases. Gene cloning, protein expression, and catalytic mechanism. J Biol Chem (1998) 1.14
Skin-homing receptors on effector leukocytes are differentially sensitive to glyco-metabolic antagonism in allergic contact dermatitis. J Immunol (2007) 1.13
Systems-level studies of glycosyltransferase gene expression and enzyme activity that are associated with the selectin binding function of human leukocytes. FASEB J (2008) 1.12
Cloning, expression and chromosomal mapping of human lysosomal sialidase and characterization of mutations in sialidosis. Nat Genet (1997) 1.11
Fluorinated per-acetylated GalNAc metabolically alters glycan structures on leukocyte PSGL-1 and reduces cell binding to selectins. Blood (2009) 1.10
Ameliorating skin-homing receptors on malignant T cells with a fluorosugar analog of N-acetylglucosamine: P-selectin ligand is a more sensitive target than E-selectin ligand. J Invest Dermatol (2006) 1.09
HCELL is the major E- and L-selectin ligand expressed on LS174T colon carcinoma cells. J Biol Chem (2006) 1.08
The monoclonal antibody CHO-131 binds to a core 2 O-glycan terminated with sialyl-Lewis x, which is a functional glycan ligand for P-selectin. Blood (2002) 1.08
A hematopoietic cell L-selectin ligand that is distinct from PSGL-1 and displays N-glycan-dependent binding activity. Blood (2000) 1.06
Development of a nascent galectin-1 chimeric molecule for studying the role of leukocyte galectin-1 ligands and immune disease modulation. J Immunol (2010) 1.04
Analysis of glycosyltransferase expression in metastatic prostate cancer cells capable of rolling activity on microvascular endothelial (E)-selectin. Glycobiology (2008) 1.00
Deoxygenated disaccharide analogs as specific inhibitors of beta1-4-galactosyltransferase 1 and selectin-mediated tumor metastasis. J Biol Chem (2008) 0.96
Fluorinated carbohydrates as potential plasma membrane modifiers. Synthesis of 4- and 6-fluoro derivatives of 2-acetamido-2-deoxy-D-hexopyranoses. Carbohydr Res (1990) 0.96
Regulation of heparan sulfate and chondroitin sulfate glycosaminoglycan biosynthesis by 4-fluoro-glucosamine in murine airway smooth muscle cells. J Biol Chem (2009) 0.96
Expression patterns of alpha 2,3-sialyltransferases and alpha 1,3-fucosyltransferases determine the mode of sialyl Lewis X inhibition by disaccharide decoys. J Biol Chem (2003) 0.95
Biochemical characteristics, metabolism, and antitumor activity of several acetylated hexosamines. J Supramol Struct (1977) 0.95
Galectin-1 as a potential therapeutic target in autoimmune disorders and cancer. Expert Opin Biol Ther (2008) 0.95
Inhibition of lectin-mediated ovarian tumor cell adhesion by sugar analogs. J Biol Chem (1994) 0.92
Human liver thermolabile phenol sulfotransferase: cDNA cloning, expression and characterization. Biochem Biophys Res Commun (1994) 0.90
Cell surface n-acetylneuraminic acid alpha2,3-galactoside-dependent intercellular adhesion of human colon cancer cells. Biochem Biophys Res Commun (1999) 0.88
Inhibition of human HT-29 colon carcinoma cell adhesion by a 4-fluoro-glucosamine analogue. Glycoconj J (1996) 0.87
Plasma membrane as a site for chemotherapeutic intervention. Adv Enzyme Regul (1978) 0.80
Carbohydrate analysis. Curr Opin Biotechnol (1993) 0.77
N-linked glycosylation in Campylobacter jejuni and its functional transfer into E. coli. Science (2002) 4.04
GlycoWorkbench: a tool for the computer-assisted annotation of mass spectra of glycans. J Proteome Res (2008) 3.85
Comparison of the methods for profiling glycoprotein glycans--HUPO Human Disease Glycomics/Proteome Initiative multi-institutional study. Glycobiology (2007) 2.71
Engineering N-linked protein glycosylation with diverse O antigen lipopolysaccharide structures in Escherichia coli. Proc Natl Acad Sci U S A (2005) 2.66
Kinetic analysis of a complete poxvirus transcriptome reveals an immediate-early class of genes. Proc Natl Acad Sci U S A (2008) 2.43
Functional analysis of the Campylobacter jejuni N-linked protein glycosylation pathway. Mol Microbiol (2005) 2.16
Comparative efficacy of neutralizing antibodies elicited by recombinant hemagglutinin proteins from avian H5N1 influenza virus. J Virol (2008) 2.14
Glycolipids as receptors for Bacillus thuringiensis crystal toxin. Science (2005) 2.05
Human sperm binding is mediated by the sialyl-Lewis(x) oligosaccharide on the zona pellucida. Science (2011) 2.02
Endosialin (TEM1, CD248) is a marker of stromal fibroblasts and is not selectively expressed on tumour endothelium. FEBS Lett (2005) 1.96
Aspects of hydrodynamic shear regulating shear-induced platelet activation and self-association of von Willebrand factor in suspension. Blood (2002) 1.95
Haloferax volcanii AglB and AglD are involved in N-glycosylation of the S-layer glycoprotein and proper assembly of the surface layer. J Mol Biol (2007) 1.90
ATP-sensitive potassium channels mediate survival during infection in mammals and insects. Nat Genet (2007) 1.83
Targeting selectins and selectin ligands in inflammation and cancer. Expert Opin Ther Targets (2007) 1.82
Glycomic profiling of cells and tissues by mass spectrometry: fingerprinting and sequencing methodologies. Methods Enzymol (2006) 1.82
Mass spectrometry in the analysis of N-linked and O-linked glycans. Curr Opin Struct Biol (2009) 1.77
Automatic annotation of matrix-assisted laser desorption/ionization N-glycan spectra. Proteomics (2005) 1.76
von Willebrand factor self-association on platelet GpIbalpha under hydrodynamic shear: effect on shear-induced platelet activation. Blood (2010) 1.75
Global metabolic inhibitors of sialyl- and fucosyltransferases remodel the glycome. Nat Chem Biol (2012) 1.70
Characterization of the oligosaccharides associated with the human ovarian tumor marker CA125. J Biol Chem (2003) 1.63
Glycomic analysis of human respiratory tract tissues and correlation with influenza virus infection. PLoS Pathog (2013) 1.62
The GlycanBuilder: a fast, intuitive and flexible software tool for building and displaying glycan structures. Source Code Biol Med (2007) 1.61
Glycomics profiling of Chinese hamster ovary cell glycosylation mutants reveals N-glycans of a novel size and complexity. J Biol Chem (2009) 1.58
The GlycanBuilder and GlycoWorkbench glycoinformatics tools: updates and new developments. Biol Chem (2012) 1.55
Mass spectrometric analysis of N- and O-glycosylation of tissues and cells. Curr Opin Struct Biol (2006) 1.53
Glycan analysis and influenza A virus infection of primary swine respiratory epithelial cells: the importance of NeuAc{alpha}2-6 glycans. J Biol Chem (2010) 1.53
Unique modifications with phosphocholine and phosphoethanolamine define alternate antigenic forms of Neisseria gonorrhoeae type IV pili. Proc Natl Acad Sci U S A (2004) 1.52
A focused microarray approach to functional glycomics: transcriptional regulation of the glycome. Glycobiology (2005) 1.49
Transglutaminase-mediated semen coagulation controls sperm storage in the malaria mosquito. PLoS Biol (2009) 1.49
Characterization of the O antigen gene cluster and structural analysis of the O antigen of Francisella tularensis subsp. tularensis. J Med Microbiol (2003) 1.48
Deletion of Cg-emb in corynebacterianeae leads to a novel truncated cell wall arabinogalactan, whereas inactivation of Cg-ubiA results in an arabinan-deficient mutant with a cell wall galactan core. J Biol Chem (2005) 1.45
AglF, aglG and aglI, novel members of a gene island involved in the N-glycosylation of the Haloferax volcanii S-layer glycoprotein. Mol Microbiol (2008) 1.45
Comparison of methods for profiling O-glycosylation: Human Proteome Organisation Human Disease Glycomics/Proteome Initiative multi-institutional study of IgA1. Mol Cell Proteomics (2009) 1.45
AglP is a S-adenosyl-L-methionine-dependent methyltransferase that participates in the N-glycosylation pathway of Haloferax volcanii. Mol Microbiol (2010) 1.41
Identification of AglE, a second glycosyltransferase involved in N glycosylation of the Haloferax volcanii S-layer glycoprotein. J Bacteriol (2008) 1.41
Alpha 1,3 fucosyltransferases are master regulators of prostate cancer cell trafficking. Proc Natl Acad Sci U S A (2009) 1.40
AglJ adds the first sugar of the N-linked pentasaccharide decorating the Haloferax volcanii S-layer glycoprotein. J Bacteriol (2010) 1.38
Hydrodynamic forces applied on intercellular bonds, soluble molecules, and cell-surface receptors. Biophys J (2004) 1.35
The minimum information required for a glycomics experiment (MIRAGE) project: improving the standards for reporting mass-spectrometry-based glycoanalytic data. Mol Cell Proteomics (2013) 1.34
Dendritic cell maturation results in pronounced changes in glycan expression affecting recognition by siglecs and galectins. J Immunol (2007) 1.34
Activation of murine CD4+ and CD8+ T lymphocytes leads to dramatic remodeling of N-linked glycans. J Immunol (2006) 1.34
N-glycosylation in Archaea: on the coordinated actions of Haloferax volcanii AglF and AglM. Mol Microbiol (2010) 1.34
Glycosylation status of haptoglobin in sera of patients with prostate cancer vs. benign prostate disease or normal subjects. Int J Cancer (2008) 1.33
Estimating the efficiency of cell capture and arrest in flow chambers: study of neutrophil binding via E-selectin and ICAM-1. Biophys J (2002) 1.33
Solution structure of human von Willebrand factor studied using small angle neutron scattering. J Biol Chem (2006) 1.33
Characterization of a putative alpha-mannosyltransferase involved in phosphatidylinositol trimannoside biosynthesis in Mycobacterium tuberculosis. Biochem J (2002) 1.31
Histo-blood group antigens act as attachment factors of rabbit hemorrhagic disease virus infection in a virus strain-dependent manner. PLoS Pathog (2011) 1.31
Glycosyltransferase function in core 2-type protein O glycosylation. Mol Cell Biol (2009) 1.30
Potent suppression of natural killer cell response mediated by the ovarian tumor marker CA125. Gynecol Oncol (2005) 1.30
Sialic acid capping of CD8beta core 1-O-glycans controls thymocyte-major histocompatibility complex class I interaction. J Biol Chem (2002) 1.29
Structural characterisation of neutrophil glycans by ultra sensitive mass spectrometric glycomics methodology. Glycoconj J (2009) 1.28
Sensitivity, principal component and flux analysis applied to signal transduction: the case of epidermal growth factor mediated signaling. Bioinformatics (2004) 1.28
A novel mechanism for LSECtin binding to Ebola virus surface glycoprotein through truncated glycans. J Biol Chem (2007) 1.27
N-glycosylation of fibroblast growth factor receptor 1 regulates ligand and heparan sulfate co-receptor binding. J Biol Chem (2006) 1.27
Latrophilin 1 and its endogenous ligand Lasso/teneurin-2 form a high-affinity transsynaptic receptor pair with signaling capabilities. Proc Natl Acad Sci U S A (2011) 1.27
Quantitative bias in Illumina TruSeq and a novel post amplification barcoding strategy for multiplexed DNA and small RNA deep sequencing. PLoS One (2011) 1.24
Automated N-glycopeptide identification using a combination of single- and tandem-MS. J Proteome Res (2007) 1.22
LosA, a key glycosyltransferase involved in the biosynthesis of a novel family of glycosylated acyltrehalose lipooligosaccharides from Mycobacterium marinum. J Biol Chem (2005) 1.20
An RNA targeted to the HIV-1 LTR promoter modulates indiscriminate off-target gene activation. Nucleic Acids Res (2007) 1.20
Glycomics analysis of Schistosoma mansoni egg and cercarial secretions. Mol Cell Proteomics (2007) 1.19
Inactivation of Corynebacterium glutamicum NCgl0452 and the role of MgtA in the biosynthesis of a novel mannosylated glycolipid involved in lipomannan biosynthesis. J Biol Chem (2006) 1.19
DAS181 inhibits H5N1 influenza virus infection of human lung tissues. Antimicrob Agents Chemother (2009) 1.18
Selectin ligand sialyl-Lewis x antigen drives metastasis of hormone-dependent breast cancers. Cancer Res (2011) 1.17
Localization of Smc5/6 to centromeres and telomeres requires heterochromatin and SUMO, respectively. EMBO J (2008) 1.16
Direct real-time observation of E- and P-selectin-mediated rolling on cutaneous lymphocyte-associated antigen immobilized on Western blots. J Immunol (2002) 1.15
Structural characterization of lipo-oligosaccharide (LOS) from Yersinia pestis: regulation of LOS structure by the PhoPQ system. Mol Microbiol (2002) 1.15
Sulfoquinovose synthase - an important enzyme in the N-glycosylation pathway of Sulfolobus acidocaldarius. Mol Microbiol (2011) 1.15
Toolboxes for a standardised and systematic study of glycans. BMC Bioinformatics (2014) 1.15
The 130-kDa glycoform of CD43 functions as an E-selectin ligand for activated Th1 cells in vitro and in delayed-type hypersensitivity reactions in vivo. J Invest Dermatol (2007) 1.15
Over-expression of ST3Gal-I promotes mammary tumorigenesis. Glycobiology (2010) 1.14