Published in Proc Natl Acad Sci U S A on May 18, 2011
On the presence and role of human gene-body DNA methylation. Oncotarget (2012) 2.10
An insight into the various regulatory mechanisms modulating human DNA methyltransferase 1 stability and function. Epigenetics (2012) 0.92
Dissection of cell cycle-dependent dynamics of Dnmt1 by FRAP and diffusion-coupled modeling. Nucleic Acids Res (2013) 0.90
Defects of mutant DNMT1 are linked to a spectrum of neurological disorders. Brain (2015) 0.87
A novel de novo exon 21 DNMT1 mutation causes cerebellar ataxia, deafness, and narcolepsy in a Brazilian patient. Sleep (2013) 0.83
Genomic survey, gene expression analysis and structural modeling suggest diverse roles of DNA methyltransferases in legumes. PLoS One (2014) 0.80
HhaI methyltransferase flips its target base out of the DNA helix. Cell (1994) 8.72
The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA. Nature (2007) 8.17
UHRF1 plays a role in maintaining DNA methylation in mammalian cells. Science (2007) 7.90
A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei. Cell (1992) 7.11
Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases. J Mol Biol (1988) 5.24
Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1. Science (1997) 5.05
Kinetic and catalytic mechanism of HhaI methyltransferase. J Biol Chem (1987) 4.84
Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation. Science (2010) 2.98
Replication-independent chromatin loading of Dnmt1 during G2 and M phases. EMBO Rep (2004) 1.98
The interaction of the SRA domain of ICBP90 with a novel domain of DNMT1 is involved in the regulation of VEGF gene expression. Oncogene (2007) 1.97
Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1). Proc Natl Acad Sci U S A (2011) 1.52
A structural basis for the preferential binding of hemimethylated DNA by HhaI DNA methyltransferase. J Mol Biol (1996) 1.40
Different binding properties and function of CXXC zinc finger domains in Dnmt1 and Tet1. PLoS One (2011) 1.30
The replication focus targeting sequence (RFTS) domain is a DNA-competitive inhibitor of Dnmt1. J Biol Chem (2011) 1.22
Structure and function of the mouse DNA methyltransferase gene: Dnmt1 shows a tripartite structure. J Mol Biol (2000) 1.13
Mouse DNA methyltransferase (MTase) deletion mutants that retain the catalytic domain display neither de novo nor maintenance methylation activity in vivo. Biol Chem (1997) 0.91
Induction of tumors in mice by genomic hypomethylation. Science (2003) 8.86
Subdiffraction multicolor imaging of the nuclear periphery with 3D structured illumination microscopy. Science (2008) 6.47
Sensitive enzymatic quantification of 5-hydroxymethylcytosine in genomic DNA. Nucleic Acids Res (2010) 4.91
A guide to super-resolution fluorescence microscopy. J Cell Biol (2010) 4.71
A versatile nanotrap for biochemical and functional studies with fluorescent fusion proteins. Mol Cell Proteomics (2007) 4.28
Cortical constriction during abscission involves helices of ESCRT-III-dependent filaments. Science (2011) 4.26
Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives. Cell (2013) 4.16
Identifying specific protein interaction partners using quantitative mass spectrometry and bead proteomes. J Cell Biol (2008) 3.53
Targeting and tracing antigens in live cells with fluorescent nanobodies. Nat Methods (2006) 3.12
Targeted transcriptional activation of silent oct4 pluripotency gene by combining designer TALEs and inhibition of epigenetic modifiers. Nucleic Acids Res (2012) 2.83
DNA polymerase clamp shows little turnover at established replication sites but sequential de novo assembly at adjacent origin clusters. Mol Cell (2002) 2.71
In vivo control of CpG and non-CpG DNA methylation by DNA methyltransferases. PLoS Genet (2012) 2.70
Recruitment of DNA methyltransferase I to DNA repair sites. Proc Natl Acad Sci U S A (2005) 2.50
LBR and lamin A/C sequentially tether peripheral heterochromatin and inversely regulate differentiation. Cell (2013) 2.38
Trapped in action: direct visualization of DNA methyltransferase activity in living cells. Nat Methods (2005) 2.26
3D-structured illumination microscopy provides novel insight into architecture of human centrosomes. Biol Open (2012) 2.23
DNMT1 but not its interaction with the replication machinery is required for maintenance of DNA methylation in human cells. J Cell Biol (2007) 2.20
Modulation of protein properties in living cells using nanobodies. Nat Struct Mol Biol (2009) 2.15
Feedback-regulated poly(ADP-ribosyl)ation by PARP-1 is required for rapid response to DNA damage in living cells. Nucleic Acids Res (2007) 2.08
Chromatin domains and the interchromatin compartment form structurally defined and functionally interacting nuclear networks. Chromosome Res (2006) 2.07
Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation. Nucleic Acids Res (2007) 2.04
Replication-independent chromatin loading of Dnmt1 during G2 and M phases. EMBO Rep (2004) 1.98
Methyl CpG-binding proteins induce large-scale chromatin reorganization during terminal differentiation. J Cell Biol (2005) 1.91
Np95 interacts with de novo DNA methyltransferases, Dnmt3a and Dnmt3b, and mediates epigenetic silencing of the viral CMV promoter in embryonic stem cells. EMBO Rep (2009) 1.89
Recognition of 5-hydroxymethylcytosine by the Uhrf1 SRA domain. PLoS One (2011) 1.88
DNA labeling in living cells. Cytometry A (2005) 1.85
The multi-domain protein Np95 connects DNA methylation and histone modification. Nucleic Acids Res (2009) 1.84
PCNA acts as a stationary loading platform for transiently interacting Okazaki fragment maturation proteins. Nucleic Acids Res (2005) 1.71
The PHD domain of Np95 (mUHRF1) is involved in large-scale reorganization of pericentromeric heterochromatin. Mol Biol Cell (2008) 1.53
Stable chromosomal units determine the spatial and temporal organization of DNA replication. J Cell Sci (2004) 1.53
DNA methylation-mediated epigenetic control. J Cell Biochem (2009) 1.49
Differential recruitment of DNA Ligase I and III to DNA repair sites. Nucleic Acids Res (2006) 1.47
Different binding properties and function of CXXC zinc finger domains in Dnmt1 and Tet1. PLoS One (2011) 1.30
XRCC1 and PCNA are loading platforms with distinct kinetic properties and different capacities to respond to multiple DNA lesions. BMC Mol Biol (2007) 1.30
MeCP2 interacts with HP1 and modulates its heterochromatin association during myogenic differentiation. Nucleic Acids Res (2007) 1.29
Probing intranuclear environments at the single-molecule level. Biophys J (2007) 1.28
Interactions within the mammalian DNA methyltransferase family. BMC Mol Biol (2003) 1.23
CENP-C facilitates the recruitment of M18BP1 to centromeric chromatin. Nucleus (2012) 1.22
Usp7 and Uhrf1 control ubiquitination and stability of the maintenance DNA methyltransferase Dnmt1. J Cell Biochem (2011) 1.20
Role of Cdc48/p97 as a SUMO-targeted segregase curbing Rad51-Rad52 interaction. Nat Cell Biol (2013) 1.20
Cell cycle markers for live cell analyses. Cell Cycle (2005) 1.18
A fluorescent two-hybrid assay for direct visualization of protein interactions in living cells. Mol Cell Proteomics (2008) 1.15
Discontinuous movement of mRNP particles in nucleoplasmic regions devoid of chromatin. Proc Natl Acad Sci U S A (2008) 1.14
Suv4-20h2 mediates chromatin compaction and is important for cohesin recruitment to heterochromatin. Genes Dev (2013) 1.13
Characterization of PvuRts1I endonuclease as a tool to investigate genomic 5-hydroxymethylcytosine. Nucleic Acids Res (2011) 1.11
PARG is recruited to DNA damage sites through poly(ADP-ribose)- and PCNA-dependent mechanisms. Nucleic Acids Res (2011) 1.11
Differentiation and large scale spatial organization of the genome. Curr Opin Genet Dev (2010) 1.09
Identification and characterization of two novel primate-specific histone H3 variants, H3.X and H3.Y. J Cell Biol (2010) 1.08
Regulation of DNA methyltransferase 1 by interactions and modifications. Nucleus (2011) 1.06
Visualization and targeted disruption of protein interactions in living cells. Nat Commun (2013) 1.05
Cooperative DNA and histone binding by Uhrf2 links the two major repressive epigenetic pathways. J Cell Biochem (2011) 1.05
MeCP2 Rett mutations affect large scale chromatin organization. Hum Mol Genet (2011) 1.05
Analysis of centriole elimination during C. elegans oogenesis. Development (2012) 1.05
Top-down de Novo protein sequencing of a 13.6 kDa camelid single heavy chain antibody by matrix-assisted laser desorption ionization-time-of-flight/time-of-flight mass spectrometry. Anal Chem (2010) 1.05
Dimerization of DNA methyltransferase 1 is mediated by its regulatory domain. J Cell Biochem (2009) 1.03
H2A.Z.2.2 is an alternatively spliced histone H2A.Z variant that causes severe nucleosome destabilization. Nucleic Acids Res (2012) 1.03
A versatile non-radioactive assay for DNA methyltransferase activity and DNA binding. Nucleic Acids Res (2009) 1.02
Histone acetylation controls the inactive X chromosome replication dynamics. Nat Commun (2011) 1.00
Targeting and tracing of specific DNA sequences with dTALEs in living cells. Nucleic Acids Res (2013) 0.99
Histone hypoacetylation is required to maintain late replication timing of constitutive heterochromatin. Nucleic Acids Res (2011) 0.99
Role for hACF1 in the G2/M damage checkpoint. Nucleic Acids Res (2011) 0.97
MBD4 and MLH1 are required for apoptotic induction in xDNMT1-depleted embryos. Development (2009) 0.97
Magnetosome expression of functional camelid antibody fragments (nanobodies) in Magnetospirillum gryphiswaldense. Appl Environ Microbiol (2011) 0.97
Generation and characterization of a rat monoclonal antibody specific for multiple red fluorescent proteins. Hybridoma (Larchmt) (2008) 0.96
Recruitment of RNA polymerase II cofactor PC4 to DNA damage sites. J Cell Biol (2008) 0.96
Spatiotemporal dynamics of p21CDKN1A protein recruitment to DNA-damage sites and interaction with proliferating cell nuclear antigen. J Cell Sci (2006) 0.95
Regulation of DNA methyltransferase 1. Adv Enzyme Regul (2006) 0.94
Nucleolar marker for living cells. Histochem Cell Biol (2007) 0.94
Step-wise assembly, maturation and dynamic behavior of the human CENP-P/O/R/Q/U kinetochore sub-complex. PLoS One (2012) 0.93
Uncoupling the replication machinery: replication fork progression in the absence of processive DNA synthesis. Cell Cycle (2008) 0.91
Restricted mobility of Dnmt1 in preimplantation embryos: implications for epigenetic reprogramming. BMC Dev Biol (2005) 0.91
Dissection of cell cycle-dependent dynamics of Dnmt1 by FRAP and diffusion-coupled modeling. Nucleic Acids Res (2013) 0.90
Engineering antibodies and proteins for molecular in vivo imaging. Curr Opin Biotechnol (2011) 0.90
Direct and dynamic detection of HIV-1 in living cells. PLoS One (2012) 0.89
Epigenetics of eu- and heterochromatin in inverted and conventional nuclei from mouse retina. Chromosome Res (2013) 0.89
Novel antibody derivatives for proteome and high-content analysis. Anal Bioanal Chem (2010) 0.88
Generation and characterization of rat and mouse monoclonal antibodies specific for MeCP2 and their use in X-inactivation studies. PLoS One (2011) 0.88
The fluorescent two-hybrid (F2H) assay for direct analysis of protein-protein interactions in living cells. Methods Mol Biol (2012) 0.87
De novo assembly of a PML nuclear subcompartment occurs through multiple pathways and induces telomere elongation. J Cell Sci (2011) 0.86
CPT1alpha over-expression increases long-chain fatty acid oxidation and reduces cell viability with incremental palmitic acid concentration in 293T cells. Biochem Biophys Res Commun (2005) 0.86
Generation and characterization of a rat monoclonal antibody specific for PCNA. Hybridoma (Larchmt) (2008) 0.85
Case study on live cell apoptosis-assay using lamin-chromobody cell-lines for high-content analysis. Methods Mol Biol (2012) 0.84
Fluorescent protein specific Nanotraps to study protein-protein interactions and histone-tail peptide binding. Methods Mol Biol (2012) 0.83
Global DNA hypomethylation prevents consolidation of differentiation programs and allows reversion to the embryonic stem cell state. PLoS One (2012) 0.83
Nuclear architecture: Is it important for genome function and can we prove it? J Cell Biochem (2007) 0.83
Reliable detection of epigenetic histone marks and nuclear proteins in tissue cryosections. Chromosome Res (2012) 0.83
Intrinsic and extrinsic connections of Tet3 dioxygenase with CXXC zinc finger modules. PLoS One (2013) 0.83
Structure, function and dynamics of nuclear subcompartments. Curr Opin Cell Biol (2012) 0.82
A CENP-S/X complex assembles at the centromere in S and G2 phases of the human cell cycle. Open Biol (2014) 0.82
A novel approach to induce cell cycle reentry in terminally differentiated muscle cells. FASEB J (2001) 0.81
Regulation and spatial organization of PCNA in Trypanosoma brucei. Biochem Biophys Res Commun (2012) 0.81
Spatiotemporal dynamics of regulatory protein recruitment at DNA damage sites. J Cell Biochem (2008) 0.80
A bacterial-two-hybrid selection system for one-step isolation of intracellularly functional Nanobodies. Arch Biochem Biophys (2012) 0.80
Binding of the heterogeneous ribonucleoprotein K (hnRNP K) to the Epstein-Barr virus nuclear antigen 2 (EBNA2) enhances viral LMP2A expression. PLoS One (2012) 0.80
Myb-binding protein 1a (Mybbp1a) regulates levels and processing of pre-ribosomal RNA. J Biol Chem (2012) 0.80
Distribution of DNA replication proteins in Drosophila cells. BMC Cell Biol (2007) 0.80
An unexpected link between energy metabolism, calcium, chromatin condensation and cell cycle. Cell Cycle (2007) 0.79
Cascaded photoinduced drug delivery to cells from multifunctional core-shell mesoporous silica. Adv Healthc Mater (2012) 0.79
A mutagenesis strategy combining systematic alanine scanning with larger mutations to study protein interactions. Anal Biochem (2007) 0.79
The polyserine domain of the lysyl-5 hydroxylase Jmjd6 mediates subnuclear localization. Biochem J (2013) 0.79