Chronic intermittent hypoxia augments sympatho-excitatory response to ATP but not to L-glutamate in the RVLM of rats.

PubWeight™: 0.85‹?›

🔗 View Article (PMID 21684220)

Published in Auton Neurosci on June 17, 2011

Authors

Daniel B Zoccal1, J Pablo Huidobro-Toro, Benedito H Machado

Author Affiliations

1: Department of Physiology, School of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.

Articles by these authors

Activation and regulation of purinergic P2X receptor channels. Pharmacol Rev (2011) 2.14

Increased sympathetic outflow in juvenile rats submitted to chronic intermittent hypoxia correlates with enhanced expiratory activity. J Physiol (2008) 1.66

P2Y(1) and P2Y(2) receptors are coupled to the NO/cGMP pathway to vasodilate the rat arterial mesenteric bed. Br J Pharmacol (2002) 1.22

Allosteric modulation of ATP-gated P2X receptor channels. Rev Neurosci (2011) 1.16

Sympathetic-mediated hypertension of awake juvenile rats submitted to chronic intermittent hypoxia is not linked to baroreflex dysfunction. Exp Physiol (2009) 1.15

Intermittent hypoxia-induced sensitization of central chemoreceptors contributes to sympathetic nerve activity during late expiration in rats. J Neurophysiol (2011) 1.10

Anandamide elicits an acute release of nitric oxide through endothelial TRPV1 receptor activation in the rat arterial mesenteric bed. J Physiol (2005) 1.07

Electrophysiological properties of rostral ventrolateral medulla presympathetic neurons modulated by the respiratory network in rats. J Neurosci (2013) 1.06

The Elav-like protein HuR exerts translational control of viral internal ribosome entry sites. Virology (2009) 1.05

Dissecting the facilitator and inhibitor allosteric metal sites of the P2X4 receptor channel: critical roles of CYS132 for zinc potentiation and ASP138 for copper inhibition. J Biol Chem (2007) 1.04

Increased sympathetic activity in rats submitted to chronic intermittent hypoxia. Exp Physiol (2006) 1.02

Differential role of extracellular histidines in copper, zinc, magnesium and proton modulation of the P2X7 purinergic receptor. J Neurochem (2007) 0.99

Differences in potency and efficacy of a series of phenylisopropylamine/phenylethylamine pairs at 5-HT(2A) and 5-HT(2C) receptors. Br J Pharmacol (2002) 0.99

Involvement of L-glutamate and ATP in the neurotransmission of the sympathoexcitatory component of the chemoreflex in the commissural nucleus tractus solitarii of awake rats and in the working heart-brainstem preparation. J Physiol (2007) 0.97

Histidine 140 plays a key role in the inhibitory modulation of the P2X4 nucleotide receptor by copper but not zinc. J Biol Chem (2003) 0.96

Sympathoexcitatory response to peripheral chemoreflex activation is enhanced in juvenile rats exposed to chronic intermittent hypoxia. Exp Physiol (2006) 0.96

Do changes in the coupling between respiratory and sympathetic activities contribute to neurogenic hypertension? Clin Exp Pharmacol Physiol (2009) 0.95

Medullary respiratory network drives sympathetic overactivity and hypertension in rats submitted to chronic intermittent hypoxia. Hypertension (2012) 0.94

Cardiovascular responses to chemoreflex activation with potassium cyanide or hypoxic hypoxia in awake rats. Auton Neurosci (2002) 0.94

NO production and eNOS phosphorylation induced by epinephrine through the activation of beta-adrenoceptors. Am J Physiol Heart Circ Physiol (2009) 0.94

Coupling between respiratory and sympathetic activities as a novel mechanism underpinning neurogenic hypertension. Curr Hypertens Rep (2011) 0.93

Specific respiratory neuron types have increased excitability that drive presympathetic neurones in neurogenic hypertension. Hypertension (2014) 0.93

Baroreflex responses to electrical stimulation of aortic depressor nerve in conscious SHR. Am J Physiol Heart Circ Physiol (2006) 0.93

Contribution of the retrotrapezoid nucleus/parafacial respiratory region to the expiratory-sympathetic coupling in response to peripheral chemoreflex in rats. J Neurophysiol (2012) 0.92

Inhibitory modulation of chemoreflex bradycardia by stimulation of the nucleus raphe obscurus is mediated by 5-HT3 receptors in the NTS of awake rats. Auton Neurosci (2006) 0.91

A2B adenosine receptor mediates human chorionic vasoconstriction and signals through arachidonic acid cascade. Am J Physiol Heart Circ Physiol (2005) 0.90

Extracellular histidine residues identify common structural determinants in the copper/zinc P2X2 receptor modulation. J Neurochem (2005) 0.89

Chronic intermittent hypoxia alters glutamatergic control of sympathetic and respiratory activities in the commissural NTS of rats. Am J Physiol Regul Integr Comp Physiol (2011) 0.89

P2Y1 and P2Y2 receptor distribution varies along the human placental vascular tree: role of nucleotides in vascular tone regulation. J Physiol (2006) 0.88

Sympathoexcitation during chemoreflex active expiration is mediated by L-glutamate in the RVLM/Bötzinger complex of rats. J Neurophysiol (2012) 0.88

The 5'-untranslated region of the mouse mammary tumor virus mRNA exhibits cap-independent translation initiation. Nucleic Acids Res (2009) 0.88

Reactive oxygen species potentiate the P2X2 receptor activity through intracellular Cys430. J Neurosci (2009) 0.87

Plasma corticosterone levels is elevated in rats submitted to chronic intermittent hypoxia. Auton Neurosci (2007) 0.87

Urethane inhibits the GABAergic neurotransmission in the nucleus of the solitary tract of rat brain stem slices. Am J Physiol Regul Integr Comp Physiol (2006) 0.87

Fos expression in the NTS in response to peripheral chemoreflex activation in awake rats. Auton Neurosci (2009) 0.87

Stoichiometry and conditional stability constants of Cu(II) or Zn(II) clioquinol complexes; implications for Alzheimer's and Huntington's disease therapy. Neurotoxicology (2007) 0.86

Modulation of respiratory responses to chemoreflex activation by L-glutamate and ATP in the rostral ventrolateral medulla of awake rats. Am J Physiol Regul Integr Comp Physiol (2011) 0.86

Short-term sustained hypoxia induces changes in the coupling of sympathetic and respiratory activities in rats. J Physiol (2014) 0.85

Glutamatergic antagonism in the NTS decreases post-inspiratory drive and changes phrenic and sympathetic coupling during chemoreflex activation. J Neurophysiol (2010) 0.84

Hemodynamic and respiratory responses to microinjection of ATP into the intermediate and caudal NTS of awake rats. Brain Res (2005) 0.84

Cardiovascular responses to microinjection of ATP into the nucleus tractus solitarii of awake rats. Am J Physiol Regul Integr Comp Physiol (2004) 0.84

Synaptic transmission of baro- and chemoreceptors afferents in the NTS second order neurons. Auton Neurosci (2013) 0.84

Heavy metals modulate the activity of the purinergic P2X4 receptor. Toxicol Appl Pharmacol (2005) 0.84

Pressor response to chemoreflex activation before and after microinjection of glycine into the NTS of awake rats. Am J Physiol Regul Integr Comp Physiol (2002) 0.83

The hypolipidemic drug metabolites nafenopin-CoA and ciprofibroyl-CoA are competitive P2Y1 receptor antagonists. FEBS Lett (2003) 0.82

Involvement of central 5-HT7 receptors in modulation of cardiovascular reflexes in awake rats. Brain Res (2007) 0.82

Chronic intermittent hypoxia depresses afferent neurotransmission in NTS neurons by a reduction in the number of active synapses. J Neurosci (2012) 0.82

4-Bromo-2,5-dimethoxyphenethylamine (2C-B) and structurally related phenylethylamines are potent 5-HT2A receptor antagonists in Xenopus laevis oocytes. Br J Pharmacol (2004) 0.82

The role of adenosine A2A and A3 receptors on the differential modulation of norepinephrine and neuropeptide Y release from peripheral sympathetic nerve terminals. J Neurochem (2006) 0.82

NO in the caudal NTS modulates the increase in respiratory frequency in response to chemoreflex activation in awake rats. Respir Physiol Neurobiol (2009) 0.82

UTP controls cell surface distribution and vasomotor activity of the human P2Y2 receptor through an epidermal growth factor receptor-transregulated mechanism. J Biol Chem (2009) 0.81

Autonomic and respiratory responses to microinjection of ATP into the intermediate or caudal nucleus tractus solitarius in the working heart-brainstem preparation of the rat. Clin Exp Pharmacol Physiol (2005) 0.81

Sensory afferent selective role of P2 receptors in the nucleus tractus solitarii for mediating the cardiac component of the peripheral chemoreceptor reflex in rats. J Physiol (2002) 0.81

Noradrenergic inhibitory modulation in the caudal commissural NTS of the pressor response to chemoreflex activation in awake rats. Auton Neurosci (2007) 0.81

Inhibition of spontaneous neurotransmission in the nucleus of solitary tract of the rat by the cannabinoid agonist WIN 55212-2 is not via CB1 or CB2 receptors. Brain Res (2008) 0.81

Chemoreflex sympathoexcitation was not altered by the antagonism of glutamate receptors in the commissural nucleus tractus solitarii in the working heart-brainstem preparation of rats. Exp Physiol (2006) 0.80

Sympathetic overactivity coupled with active expiration in rats submitted to chronic intermittent hypoxia. Respir Physiol Neurobiol (2010) 0.80

Effect of 5-HT depletion on cardiovascular vagal reflex sensitivity in awake and anesthetized rats. Brain Res (2005) 0.80

A cis-acting element present within the Gag open reading frame negatively impacts on the activity of the HIV-1 IRES. PLoS One (2013) 0.80

Autonomic and respiratory responses to microinjection of L-glutamate into the commissural subnucleus of the NTS in the working heart-brainstem preparation of the rat. Brain Res (2006) 0.80

NMDA receptor antagonism blocks the cardiovascular responses to microinjection of trans-ACPD into the NTS of awake rats. Exp Physiol (2004) 0.79

Glial cells modulate the synaptic transmission of NTS neurons sending projections to ventral medulla of Wistar rats. Physiol Rep (2013) 0.79

Electrophysiological properties of laryngeal motoneurones in rats submitted to chronic intermittent hypoxia. J Physiol (2015) 0.79

Glutamatergic and purinergic mechanisms on respiratory modulation in the caudal NTS of awake rats. Respir Physiol Neurobiol (2008) 0.78

Involvement of the parabrachial nucleus in the pressor response to chemoreflex activation in awake rats. Auton Neurosci (2002) 0.78

alpha2-Adrenoceptors control the release of noradrenaline but not neuropeptide Y from perivascular nerve terminals. Peptides (2002) 0.78

Immunoreactivity for neuronal NOS and fluorescent indication of NO formation in the NTS of juvenile rats submitted to chronic intermittent hypoxia. Auton Neurosci (2009) 0.78

Respiratory and autonomic responses to microinjection of NMDA and AMPA into the commissural subnucleus of the NTS of awake rats. Brain Res (2005) 0.78

Acute inhibition of glial cells in the NTS does not affect respiratory and sympathetic activities in rats exposed to chronic intermittent hypoxia. Brain Res (2012) 0.78

Modulation of arterial pressure by P2 purinoceptors in the paraventricular nucleus of the hypothalamus of awake rats. Auton Neurosci (2010) 0.78

Antagonism of glutamatergic metabotropic receptors in the NTS of awake rats does not affect the gain of the baroreflex. Auton Neurosci (2003) 0.78

Fluorescent indication that nitric oxide formation in NTS neurons is modulated by glutamate and GABA. Nitric Oxide (2009) 0.78

Neuropeptide Y is released from human mammary and radial vascular biopsies and is a functional modulator of sympathetic cotransmission. J Vasc Res (2004) 0.78

Neuromodulator role of zinc and copper during prolonged ATP applications to P2X4 purinoceptors. Eur J Pharmacol (2003) 0.78

Are L-glutamate and ATP cotransmitters of the peripheral chemoreflex in the rat nucleus tractus solitarius? Exp Physiol (2008) 0.77

Dopamine microinjected into brainstem of awake rats affects baseline arterial pressure but not chemoreflex responses. Auton Neurosci (2010) 0.77

Cardiovascular responses to ATP microinjected into the paraventricular nucleus are mediated by nitric oxide and NMDA glutamate receptors in awake rats. Exp Physiol (2013) 0.77

Lipopolysaccharide inhibits the channel activity of the P2X7 receptor. Mediators Inflamm (2011) 0.77

Involvement of NMDA receptors in the pressor response to microinjection of 5-HT3 agonist into the NTS of awake rats. Auton Neurosci (2002) 0.77

Ischaemia-induced sympathoexcitation in spinalyzed rats. Neurosci Lett (2006) 0.77

Formation of carnosine-Cu(II) complexes prevents and reverts the inhibitory action of copper in P2X4 and P2X7 receptors. J Neurochem (2002) 0.76

The human prion octarepeat fragment prevents and reverses the inhibitory action of copper in the P2X4 receptor without modifying the zinc action. J Neurochem (2003) 0.76

GABA and nitric oxide in the PVN are involved in arterial pressure control but not in the chemoreflex responses in rats. Auton Neurosci (2009) 0.76

Interaction of purinergic and nitrergic mechanisms in the caudal nucleus tractus solitarii of rats. Auton Neurosci (2009) 0.76

P2Y1 receptor activation elicits its partition out of membrane rafts and its rapid internalization from human blood vessels: implications for receptor signaling. Mol Pharmacol (2008) 0.76

Release and functional role of neuropeptide Y as a sympathetic modulator in human saphenous vein biopsies. Peptides (2004) 0.76

Modulator role of neuropeptide Y in human vascular sympathetic neuroeffector junctions. EXS (2006) 0.75

Activation of peripheral chemoreceptors causes positive inotropic effects in a working heart-brainstem preparation of the rat. Clin Exp Pharmacol Physiol (2007) 0.75

The Cellular Prion Protein Prevents Copper-Induced Inhibition of P2X(4) Receptors. Int J Alzheimers Dis (2011) 0.75

Cardiovascular responses to microinjection of AMPA into the rostral commissural nucleus tractus solitarius of awake rats. Auton Neurosci (2003) 0.75

Pressor response to chemoreflex activation in awake rats: role of vasopressin and adrenal medulla. Physiol Behav (2005) 0.75

Frontiers in Research Review: Stress and Hypertension. Introduction. Clin Exp Pharmacol Physiol (2011) 0.75

IV Miguel R. Covian Symposium: new challenges for physiologists. Braz J Med Biol Res (2009) 0.75

Water deprivation increases Fos expression in hypothalamic corticotropin-releasing factor neurons induced by right atrial distension in awake rats. Am J Physiol Regul Integr Comp Physiol (2008) 0.75

Central control of autonomic and respiratory functions in health and diseases. Auton Neurosci (2013) 0.75

Cardiovascular and respiratory responses to chronic intermittent hypoxia in adult female rats. Exp Physiol (2015) 0.75