Published in PLoS One on June 09, 2011
CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands. Nat Med (2016) 2.40
The cytokine IL-22 promotes pathogen colonization by suppressing related commensal bacteria. Immunity (2014) 2.22
Intestinal colonization resistance. Immunology (2013) 1.85
'Blooming' in the gut: how dysbiosis might contribute to pathogen evolution. Nat Rev Microbiol (2013) 1.45
Granulocytes impose a tight bottleneck upon the gut luminal pathogen population during Salmonella typhimurium colitis. PLoS Pathog (2014) 1.44
The role of the immune system in governing host-microbe interactions in the intestine. Nat Immunol (2013) 1.41
Innate immune response to Salmonella typhimurium, a model enteric pathogen. Gut Microbes (2012) 1.33
The gut commensal Bacteroides thetaiotaomicron exacerbates enteric infection through modification of the metabolic landscape. Cell Host Microbe (2014) 1.25
Protective role of commensals against Clostridium difficile infection via an IL-1β-mediated positive-feedback loop. J Immunol (2012) 1.24
A Multi-Omic View of Host-Pathogen-Commensal Interplay in Salmonella-Mediated Intestinal Infection. PLoS One (2013) 1.14
Plasticity of the β-trefoil protein fold in the recognition and control of invertebrate predators and parasites by a fungal defence system. PLoS Pathog (2012) 1.05
Innate immune signaling in defense against intestinal microbes. Immunol Rev (2012) 1.00
Neutrophil elastase alters the murine gut microbiota resulting in enhanced Salmonella colonization. PLoS One (2012) 0.95
Salmonella transiently reside in luminal neutrophils in the inflamed gut. PLoS One (2012) 0.92
Very long O-antigen chains enhance fitness during Salmonella-induced colitis by increasing bile resistance. PLoS Pathog (2012) 0.90
The bactericidal activity of the C-type lectin RegIIIβ against Gram-negative bacteria involves binding to lipid A. J Biol Chem (2012) 0.87
Intestinal antimicrobial peptides during homeostasis, infection, and disease. Front Immunol (2012) 0.86
Innate immune detection of flagellin positively and negatively regulates salmonella infection. PLoS One (2013) 0.86
Juvenile ferric iron prevents microbiota dysbiosis and colitis in adult rodents. World J Gastroenterol (2012) 0.83
Interleukin-22 Signaling in the Regulation of Intestinal Health and Disease. Front Cell Dev Biol (2016) 0.80
Chemoprevention in gastrointestinal physiology and disease. Natural products and microbiome. Am J Physiol Gastrointest Liver Physiol (2014) 0.80
Regulation of the gut microbiota by the mucosal immune system in mice. Int Immunol (2014) 0.80
Intestinal inflammation responds to microbial tissue load independent of pathogen/non-pathogen discrimination. PLoS One (2012) 0.79
Outer membrane permeabilization is an essential step in the killing of gram-negative bacteria by the lectin RegIIIβ. PLoS One (2013) 0.77
Interaction between the gut microbiome and mucosal immune system. Mil Med Res (2017) 0.75
Nutrient Deprivation Affects Salmonella Invasion and Its Interaction with the Gastrointestinal Microbiota. PLoS One (2016) 0.75
Exploiting a host-commensal interaction to promote intestinal barrier function and enteric pathogen tolerance. Sci Immunol (2016) 0.75
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Natl Acad Sci U S A (2000) 96.90
Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines. Nature (1981) 19.90
Peptidoglycan types of bacterial cell walls and their taxonomic implications. Bacteriol Rev (1972) 19.14
Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function. Immunity (1998) 18.12
Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli. Proc Natl Acad Sci U S A (2002) 13.83
Control selection for RNA quantitation. Biotechniques (2000) 11.36
Symbiotic bacteria direct expression of an intestinal bactericidal lectin. Science (2006) 9.95
Salmonella enterica serovar typhimurium exploits inflammation to compete with the intestinal microbiota. PLoS Biol (2007) 7.58
Colonization resistance of the digestive tract in conventional and antibiotic-treated mice. J Hyg (Lond) (1971) 7.03
Pretreatment of mice with streptomycin provides a Salmonella enterica serovar Typhimurium colitis model that allows analysis of both pathogen and host. Infect Immun (2003) 6.82
Gut inflammation provides a respiratory electron acceptor for Salmonella. Nature (2010) 6.25
Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface. Proc Natl Acad Sci U S A (2008) 5.78
RESISTANCE OF THE MOUSE'S INTESTINAL TRACT TO EXPERIMENTAL SALMONELLA INFECTION. I. FACTORS WHICH INTERFERE WITH THE INITIATION OF INFECTION BY ORAL INOCULATION. J Exp Med (1964) 5.63
Host-mediated inflammation disrupts the intestinal microbiota and promotes the overgrowth of Enterobacteriaceae. Cell Host Microbe (2007) 5.56
Salmonellae interplay with host cells. Nat Rev Microbiol (2008) 5.26
Enteric salmonellosis disrupts the microbial ecology of the murine gastrointestinal tract. Infect Immun (2007) 5.06
The Salmonella typhimurium invasion genes invF and invG encode homologues of the AraC and PulD family of proteins. Mol Microbiol (1994) 4.48
Lipocalin-2 resistance confers an advantage to Salmonella enterica serotype Typhimurium for growth and survival in the inflamed intestine. Cell Host Microbe (2009) 4.20
MyD88-mediated signals induce the bactericidal lectin RegIII gamma and protect mice against intestinal Listeria monocytogenes infection. J Exp Med (2007) 3.79
Microbial contamination of drinking water and disease outcomes in developing regions. Toxicology (2004) 3.74
Antibiotic-induced perturbations of the intestinal microbiota alter host susceptibility to enteric infection. Infect Immun (2008) 3.68
Antibiotic treatment of clostridium difficile carrier mice triggers a supershedder state, spore-mediated transmission, and severe disease in immunocompromised hosts. Infect Immun (2009) 3.36
The Salmonella pathogenicity island (SPI)-2 and SPI-1 type III secretion systems allow Salmonella serovar typhimurium to trigger colitis via MyD88-dependent and MyD88-independent mechanisms. J Immunol (2005) 3.14
The role of microbiota in infectious disease. Trends Microbiol (2008) 3.11
Host transmission of Salmonella enterica serovar Typhimurium is controlled by virulence factors and indigenous intestinal microbiota. Infect Immun (2007) 2.80
Like will to like: abundances of closely related species can predict susceptibility to intestinal colonization by pathogenic and commensal bacteria. PLoS Pathog (2010) 2.79
Robust Salmonella metabolism limits possibilities for new antimicrobials. Nature (2006) 2.78
Transfer of palmitate from phospholipids to lipid A in outer membranes of gram-negative bacteria. EMBO J (2000) 2.64
The pathogen-associated iroA gene cluster mediates bacterial evasion of lipocalin 2. Proc Natl Acad Sci U S A (2006) 2.63
Salmochelins, siderophores of Salmonella enterica and uropathogenic Escherichia coli strains, are recognized by the outer membrane receptor IroN. Proc Natl Acad Sci U S A (2003) 2.56
Role of the Salmonella pathogenicity island 1 effector proteins SipA, SopB, SopE, and SopE2 in Salmonella enterica subspecies 1 serovar Typhimurium colitis in streptomycin-pretreated mice. Infect Immun (2004) 2.46
Salmonella enterica serovar Typhimurium pathogenicity island 2 is necessary for complete virulence in a mouse model of infectious enterocolitis. Infect Immun (2005) 2.32
A PhoP/PhoQ-induced Lipase (PagL) that catalyzes 3-O-deacylation of lipid A precursors in membranes of Salmonella typhimurium. J Biol Chem (2000) 2.32
The microbiota mediates pathogen clearance from the gut lumen after non-typhoidal Salmonella diarrhea. PLoS Pathog (2010) 2.17
A mouse model for S. typhimurium-induced enterocolitis. Trends Microbiol (2005) 2.09
Mechanisms controlling pathogen colonization of the gut. Curr Opin Microbiol (2010) 1.88
Analysis of the contribution of Salmonella pathogenicity islands 1 and 2 to enteric disease progression using a novel bovine ileal loop model and a murine model of infectious enterocolitis. Infect Immun (2005) 1.88
Refolding, purification, and characterization of human and murine RegIII proteins expressed in Escherichia coli. Protein Expr Purif (2006) 1.83
In vivo actin cross-linking induced by Vibrio cholerae type VI secretion system is associated with intestinal inflammation. Proc Natl Acad Sci U S A (2010) 1.79
Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins. J Biol Chem (2006) 1.69
Motility allows S. Typhimurium to benefit from the mucosal defence. Cell Microbiol (2008) 1.69
Interaction of probiotic Lactobacillus and Bifidobacterium strains with human intestinal epithelial cells: adhesion properties, competition against enteropathogens and modulation of IL-8 production. Int J Food Microbiol (2008) 1.61
Growth of salmonellae in orally infected germfree mice. Infect Immun (1978) 1.58
Clinical use of E. coli Nissle 1917 in inflammatory bowel disease. Inflamm Bowel Dis (2008) 1.53
The PhoP/PhoQ two-component system stabilizes the alternative sigma factor RpoS in Salmonella enterica. Proc Natl Acad Sci U S A (2006) 1.44
Construction of defined galE mutants of Salmonella for use as vaccines. J Infect Dis (1987) 1.37
Dual strategies for peptidoglycan discrimination by peptidoglycan recognition proteins (PGRPs). Proc Natl Acad Sci U S A (2006) 1.35
Molecular basis for peptidoglycan recognition by a bactericidal lectin. Proc Natl Acad Sci U S A (2010) 1.34
Toll-like receptor 2 is critical for induction of Reg3 beta expression and intestinal clearance of Yersinia pseudotuberculosis. Gut (2009) 1.28
Differentiation of Streptococcus faecalis Andrewes and Horder and Streptococcus faecium Orla-Jensen based on the amino acid composition of their murein. J Bacteriol (1968) 1.21
["Lactobacillus murinus" n. sp., a new species of the autochtoneous dominant flora of the digestive tract of rat and mouse (author's transl)]. Ann Microbiol (Paris) (1980) 1.15
Antagonistic effect of Lactobacillus acidophilus, Saccharomyces boulardii and Escherichia coli combinations against experimental infections with Shigella flexneri and Salmonella enteritidis subsp. typhimurium in gnotobiotic mice. J Appl Microbiol (2000) 1.12
O-antigen-negative Salmonella enterica serovar Typhimurium is attenuated in intestinal colonization but elicits colitis in streptomycin-treated mice. Infect Immun (2009) 1.10
Capacity of human nisin- and pediocin-producing lactic Acid bacteria to reduce intestinal colonization by vancomycin-resistant enterococci. Appl Environ Microbiol (2008) 1.06
Solitary intestinal lymphoid tissue provides a productive port of entry for Salmonella enterica serovar Typhimurium. Infect Immun (2007) 1.06
Exoproducts of the Escherichia coli strain H22 inhibiting some enteric pathogens both in vitro and in vivo. J Appl Microbiol (2006) 1.06
Salmonella-induced enteritis: molecular pathogenesis and therapeutic implications. Expert Rev Mol Med (2007) 1.01
Molecular insights into the assembly and diversity of the outer core oligosaccharide in lipopolysaccharides from Escherichia coli and Salmonella. J Endotoxin Res (2003) 0.98
Gene expression response of the rat small intestine following oral Salmonella infection. Physiol Genomics (2007) 0.98
Salmonella induces prominent gene expression in the rat colon. BMC Microbiol (2007) 0.96
Host-bacteria homeostasis in the healthy and inflamed gut. Curr Opin Gastroenterol (2008) 0.93
Absence of poly(ADP-ribose) polymerase 1 delays the onset of Salmonella enterica serovar Typhimurium-induced gut inflammation. Infect Immun (2010) 0.83
Antimicrobial therapy of salmonelloses--current state and perspectives. Folia Med (Plovdiv) (2006) 0.79
Phages and the evolution of bacterial pathogens: from genomic rearrangements to lysogenic conversion. Microbiol Mol Biol Rev (2004) 7.93
Salmonella enterica serovar typhimurium exploits inflammation to compete with the intestinal microbiota. PLoS Biol (2007) 7.58
Pretreatment of mice with streptomycin provides a Salmonella enterica serovar Typhimurium colitis model that allows analysis of both pathogen and host. Infect Immun (2003) 6.82
Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth. Science (2011) 5.46
Intestinal lamina propria dendritic cell subsets have different origin and functions. Immunity (2009) 5.43
Innate and adaptive immunity cooperate flexibly to maintain host-microbiota mutualism. Science (2009) 4.45
The Salmonella pathogenicity island (SPI)-2 and SPI-1 type III secretion systems allow Salmonella serovar typhimurium to trigger colitis via MyD88-dependent and MyD88-independent mechanisms. J Immunol (2005) 3.14
The role of microbiota in infectious disease. Trends Microbiol (2008) 3.11
Self-destructive cooperation mediated by phenotypic noise. Nature (2008) 3.07
The Salmonella enterica serotype typhimurium effector proteins SipA, SopA, SopB, SopD, and SopE2 act in concert to induce diarrhea in calves. Infect Immun (2002) 2.88
Enhanced CellClassifier: a multi-class classification tool for microscopy images. BMC Bioinformatics (2010) 2.84
Like will to like: abundances of closely related species can predict susceptibility to intestinal colonization by pathogenic and commensal bacteria. PLoS Pathog (2010) 2.79
Robust Salmonella metabolism limits possibilities for new antimicrobials. Nature (2006) 2.78
Stabilization of cooperative virulence by the expression of an avirulent phenotype. Nature (2013) 2.47
Role of the Salmonella pathogenicity island 1 effector proteins SipA, SopB, SopE, and SopE2 in Salmonella enterica subspecies 1 serovar Typhimurium colitis in streptomycin-pretreated mice. Infect Immun (2004) 2.46
Flagella and chemotaxis are required for efficient induction of Salmonella enterica serovar Typhimurium colitis in streptomycin-pretreated mice. Infect Immun (2004) 2.41
Clostridium difficile toxin CDT induces formation of microtubule-based protrusions and increases adherence of bacteria. PLoS Pathog (2009) 2.29
Specific inhibition of diverse pathogens in human cells by synthetic microRNA-like oligonucleotides inferred from RNAi screens. Proc Natl Acad Sci U S A (2014) 2.25
The microbiota mediates pathogen clearance from the gut lumen after non-typhoidal Salmonella diarrhea. PLoS Pathog (2010) 2.17
A mouse model for S. typhimurium-induced enterocolitis. Trends Microbiol (2005) 2.09
Microbe sampling by mucosal dendritic cells is a discrete, MyD88-independent step in DeltainvG S. Typhimurium colitis. J Exp Med (2008) 1.92
Gut inflammation can boost horizontal gene transfer between pathogenic and commensal Enterobacteriaceae. Proc Natl Acad Sci U S A (2012) 1.90
Mechanisms controlling pathogen colonization of the gut. Curr Opin Microbiol (2010) 1.88
Real-time imaging of type III secretion: Salmonella SipA injection into host cells. Proc Natl Acad Sci U S A (2005) 1.85
A Burkholderia pseudomallei type III secreted protein, BopE, facilitates bacterial invasion of epithelial cells and exhibits guanine nucleotide exchange factor activity. J Bacteriol (2003) 1.78
Identification of surface proteins of Helicobacter pylori by selective biotinylation, affinity purification, and two-dimensional gel electrophoresis. J Biol Chem (2002) 1.76
The S. Typhimurium effector SopE induces caspase-1 activation in stromal cells to initiate gut inflammation. Cell Host Microbe (2009) 1.74
Salmonella type III secretion effectors: pulling the host cell's strings. Curr Opin Microbiol (2006) 1.70
Motility allows S. Typhimurium to benefit from the mucosal defence. Cell Microbiol (2008) 1.69
Structural basis for the reversible activation of a Rho protein by the bacterial toxin SopE. EMBO J (2002) 1.64
The intestinal microbiota, a leaky gut, and abnormal immunity in kidney disease. Kidney Int (2013) 1.64
The cost of virulence: retarded growth of Salmonella Typhimurium cells expressing type III secretion system 1. PLoS Pathog (2011) 1.60
Comparison of Salmonella enterica serovar Typhimurium colitis in germfree mice and mice pretreated with streptomycin. Infect Immun (2005) 1.59
Role of the Salmonella pathogenicity island 1 (SPI-1) protein InvB in type III secretion of SopE and SopE2, two Salmonella effector proteins encoded outside of SPI-1. J Bacteriol (2003) 1.54
Salmonella effectors within a single pathogenicity island are differentially expressed and translocated by separate type III secretion systems. Mol Microbiol (2002) 1.51
A community effort towards a knowledge-base and mathematical model of the human pathogen Salmonella Typhimurium LT2. BMC Syst Biol (2011) 1.50
Rapidly maturing red fluorescent protein variants with strongly enhanced brightness in bacteria. FEBS Lett (2003) 1.45
'Blooming' in the gut: how dysbiosis might contribute to pathogen evolution. Nat Rev Microbiol (2013) 1.45
The RD1 proteins of Mycobacterium tuberculosis: expression in Mycobacterium smegmatis and biochemical characterization. Microbes Infect (2003) 1.45
TLR5 signaling stimulates the innate production of IL-17 and IL-22 by CD3(neg)CD127+ immune cells in spleen and mucosa. J Immunol (2010) 1.43
Microbial quest for food in vivo: 'nutritional virulence' as an emerging paradigm. Cell Microbiol (2013) 1.41
Salmonella Pathogenicity Island 4 encodes a giant non-fimbrial adhesin and the cognate type 1 secretion system. Cell Microbiol (2007) 1.39
Microscopic rotary mechanism of ion translocation in the F(o) complex of ATP synthases. Nat Chem Biol (2010) 1.39
Complete ion-coordination structure in the rotor ring of Na+-dependent F-ATP synthases. J Mol Biol (2009) 1.34
The streptomycin mouse model for Salmonella diarrhea: functional analysis of the microbiota, the pathogen's virulence factors, and the host's mucosal immune response. Immunol Rev (2012) 1.30
A simple screen to identify promoters conferring high levels of phenotypic noise. PLoS Genet (2008) 1.28
RNAi screen of Salmonella invasion shows role of COPI in membrane targeting of cholesterol and Cdc42. Mol Syst Biol (2011) 1.27
The SopEPhi phage integrates into the ssrA gene of Salmonella enterica serovar Typhimurium A36 and is closely related to the Fels-2 prophage. J Bacteriol (2003) 1.26
Salmonella gut invasion involves TTSS-2-dependent epithelial traversal, basolateral exit, and uptake by epithelium-sampling lamina propria phagocytes. Cell Host Microbe (2012) 1.26
Peptide mass fingerprinting. Methods (2005) 1.24
Parallel exploitation of diverse host nutrients enhances Salmonella virulence. PLoS Pathog (2013) 1.24
Lack of mismatch correction facilitates genome evolution in mycobacteria. Mol Microbiol (2004) 1.21
Bacteriophage-encoded type III effectors in Salmonella enterica subspecies 1 serovar Typhimurium. Infect Genet Evol (2005) 1.20
Structure of the c(10) ring of the yeast mitochondrial ATP synthase in the open conformation. Nat Struct Mol Biol (2012) 1.20
Chronic Salmonella enterica serovar Typhimurium-induced colitis and cholangitis in streptomycin-pretreated Nramp1+/+ mice. Infect Immun (2006) 1.19
Phage mediated horizontal transfer of the sopE1 gene increases enteropathogenicity of Salmonella enterica serotype Typhimurium for calves. FEMS Microbiol Lett (2002) 1.19
InvB is required for type III-dependent secretion of SopA in Salmonella enterica serovar Typhimurium. J Bacteriol (2004) 1.19
Caspase-1 has both proinflammatory and regulatory properties in Helicobacter infections, which are differentially mediated by its substrates IL-1β and IL-18. J Immunol (2012) 1.19
Hierarchical effector protein transport by the Salmonella Typhimurium SPI-1 type III secretion system. PLoS One (2008) 1.18
Type III secretion of Salmonella enterica serovar Typhimurium translocated effectors and SseFG. Infect Immun (2002) 1.16
Identification and isolation of murine antigen-reactive T cells according to CD154 expression. Eur J Immunol (2007) 1.15
Virulence of broad- and narrow-host-range Salmonella enterica serovars in the streptomycin-pretreated mouse model. Infect Immun (2006) 1.14
Molecular dissection of Salmonella-induced membrane ruffling versus invasion. Cell Microbiol (2009) 1.10
Near surface swimming of Salmonella Typhimurium explains target-site selection and cooperative invasion. PLoS Pathog (2012) 1.10
O-antigen-negative Salmonella enterica serovar Typhimurium is attenuated in intestinal colonization but elicits colitis in streptomycin-treated mice. Infect Immun (2009) 1.10
Two newly identified SipA domains (F1, F2) steer effector protein localization and contribute to Salmonella host cell manipulation. Mol Microbiol (2007) 1.09
Inhibitory performance, response speed, intraindividual variability, and response accuracy in ADHD. J Am Acad Child Adolesc Psychiatry (2008) 1.09
Stromal IFN-γR-signaling modulates goblet cell function during Salmonella Typhimurium infection. PLoS One (2011) 1.08
Antigen selection based on expression levels during infection facilitates vaccine development for an intracellular pathogen. Proc Natl Acad Sci U S A (2004) 1.06
Solitary intestinal lymphoid tissue provides a productive port of entry for Salmonella enterica serovar Typhimurium. Infect Immun (2007) 1.06
Salmonella enterica highly expressed genes are disease specific. Infect Immun (2006) 1.06
Proteins unique to intraphagosomally grown Mycobacterium tuberculosis. Proteomics (2006) 1.04
Host-compound foraging by intestinal microbiota revealed by single-cell stable isotope probing. Proc Natl Acad Sci U S A (2013) 1.03
Activation of a RhoA/myosin II-dependent but Arp2/3 complex-independent pathway facilitates Salmonella invasion. Cell Host Microbe (2011) 1.02
Immunity to intracellular Salmonella depends on surface-associated antigens. PLoS Pathog (2012) 1.02
Analyses of the evolutionary distribution of Salmonella translocated effectors. Infect Immun (2002) 1.00
Lymph node colonization dynamics after oral Salmonella Typhimurium infection in mice. PLoS Pathog (2013) 1.00
A new type of Na(+)-driven ATP synthase membrane rotor with a two-carboxylate ion-coupling motif. PLoS Biol (2013) 0.98
Accelerated type III secretion system 2-dependent enteropathogenesis by a Salmonella enterica serovar enteritidis PT4/6 strain. Infect Immun (2009) 0.96
Salmonella enterica serovar Typhimurium binds to HeLa cells via Fim-mediated reversible adhesion and irreversible type three secretion system 1-mediated docking. Infect Immun (2010) 0.96
Autodisplay: efficacious surface exposure of antigenic UreA fragments from Helicobacter pylori in Salmonella vaccine strains. Infect Immun (2003) 0.95