Published in Curr Opin Microbiol on October 28, 2010
Role of the gut microbiota in immunity and inflammatory disease. Nat Rev Immunol (2013) 4.34
Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection. Nat Commun (2014) 2.39
Diet-induced dysbiosis of the intestinal microbiota and the effects on immunity and disease. Nutrients (2012) 2.10
Gut inflammation can boost horizontal gene transfer between pathogenic and commensal Enterobacteriaceae. Proc Natl Acad Sci U S A (2012) 1.90
Rapid fucosylation of intestinal epithelium sustains host-commensal symbiosis in sickness. Nature (2014) 1.78
Epithelial IL-22RA1-mediated fucosylation promotes intestinal colonization resistance to an opportunistic pathogen. Cell Host Microbe (2014) 1.66
Intestinal microbiota shifts towards elevated commensal Escherichia coli loads abrogate colonization resistance against Campylobacter jejuni in mice. PLoS One (2012) 1.63
An update on the use and investigation of probiotics in health and disease. Gut (2013) 1.62
Bacteria and host interactions in the gut epithelial barrier. Nat Chem Biol (2011) 1.54
'Blooming' in the gut: how dysbiosis might contribute to pathogen evolution. Nat Rev Microbiol (2013) 1.45
The Typhoid Toxin Promotes Host Survival and the Establishment of a Persistent Asymptomatic Infection. PLoS Pathog (2016) 1.43
Campylobacter jejuni induces acute enterocolitis in gnotobiotic IL-10-/- mice via Toll-like-receptor-2 and -4 signaling. PLoS One (2012) 1.42
Nutritional basis for colonization resistance by human commensal Escherichia coli strains HS and Nissle 1917 against E. coli O157:H7 in the mouse intestine. PLoS One (2013) 1.34
Clostridium difficile infection: toxins and non-toxin virulence factors, and their contributions to disease establishment and host response. Gut Microbes (2012) 1.33
Long-term temporal analysis of the human fecal microbiota revealed a stable core of dominant bacterial species. PLoS One (2013) 1.31
A type VI secretion-related pathway in Bacteroidetes mediates interbacterial antagonism. Cell Host Microbe (2014) 1.30
Reductions in intestinal Clostridiales precede the development of nosocomial Clostridium difficile infection. Microbiome (2013) 1.26
The role of the lung microbiome in health and disease. A National Heart, Lung, and Blood Institute workshop report. Am J Respir Crit Care Med (2013) 1.26
Barcoded pyrosequencing reveals that consumption of galactooligosaccharides results in a highly specific bifidogenic response in humans. PLoS One (2011) 1.26
The human microbiome: from symbiosis to pathogenesis. Annu Rev Med (2013) 1.25
Campylobacter jejuni infection of infant mice: acute enterocolitis is followed by asymptomatic intestinal and extra-intestinal immune responses. Eur J Microbiol Immunol (Bp) (2012) 1.24
Microbiota-mediated inflammation and antimicrobial defense in the intestine. Annu Rev Immunol (2015) 1.23
Salmonella-induced mucosal lectin RegIIIβ kills competing gut microbiota. PLoS One (2011) 1.20
The starting lineup: key microbial players in intestinal immunity and homeostasis. Front Microbiol (2011) 1.16
A Multi-Omic View of Host-Pathogen-Commensal Interplay in Salmonella-Mediated Intestinal Infection. PLoS One (2013) 1.14
Functional flexibility of intestinal IgA - broadening the fine line. Front Immunol (2012) 1.13
Age-related differences in the cloacal microbiota of a wild bird species. BMC Ecol (2013) 1.12
Factors that explain excretion of enteric pathogens by persons without diarrhea. Clin Infect Dis (2012) 1.09
Stromal IFN-γR-signaling modulates goblet cell function during Salmonella Typhimurium infection. PLoS One (2011) 1.08
Inflammation and colorectal cancer, when microbiota-host mutualism breaks. World J Gastroenterol (2014) 1.06
Association with soil bacteria enhances p38-dependent infection resistance in Caenorhabditis elegans. Infect Immun (2012) 1.01
Emerging insights on intestinal dysbiosis during bacterial infections. Curr Opin Microbiol (2013) 0.99
Interaction of Salmonella spp. with the Intestinal Microbiota. Front Microbiol (2011) 0.98
Early innate immunity to bacterial infection in the lung is regulated systemically by the commensal microbiota via nod-like receptor ligands. Infect Immun (2014) 0.98
Expression of the blood-group-related glycosyltransferase B4galnt2 influences the intestinal microbiota in mice. ISME J (2012) 0.98
Structural and functional changes in the gut microbiota associated to Clostridium difficile infection. Front Microbiol (2014) 0.97
Microbial and metabolic interactions between the gastrointestinal tract and Clostridium difficile infection. Gut Microbes (2013) 0.94
Social interaction, noise and antibiotic-mediated switches in the intestinal microbiota. PLoS Comput Biol (2012) 0.94
Salmonella transiently reside in luminal neutrophils in the inflamed gut. PLoS One (2012) 0.92
Commensal and Pathogenic Escherichia coli Metabolism in the Gut. Microbiol Spectr (2015) 0.90
Host-Derived Sialic Acids Are an Important Nutrient Source Required for Optimal Bacterial Fitness In Vivo. MBio (2016) 0.90
Fast food fever: reviewing the impacts of the Western diet on immunity. Nutr J (2014) 0.89
Seroprevalence of campylobacteriosis and relevant post-infectious sequelae. Eur J Clin Microbiol Infect Dis (2014) 0.89
Inflammation fuels colicin Ib-dependent competition of Salmonella serovar Typhimurium and E. coli in enterobacterial blooms. PLoS Pathog (2014) 0.89
Genomic features of a bumble bee symbiont reflect its host environment. Appl Environ Microbiol (2014) 0.88
Campylobacter jejuni colonization is associated with a dysbiosis in the cecal microbiota of mice in the absence of prominent inflammation. PLoS One (2013) 0.87
Salmonella enterica invasion of polarized epithelial cells is a highly cooperative effort. Infect Immun (2014) 0.87
Effector and memory T cell responses to commensal bacteria. Trends Immunol (2013) 0.86
The nonfermentable dietary fiber hydroxypropyl methylcellulose modulates intestinal microbiota. FASEB J (2012) 0.85
The Enteric Two-Step: nutritional strategies of bacterial pathogens within the gut. Cell Microbiol (2014) 0.85
Helicobacter and salmonella persistent infection strategies. Cold Spring Harb Perspect Med (2013) 0.85
Phylogenetic and Metabolic Tracking of Gut Microbiota during Perinatal Development. PLoS One (2015) 0.84
Rational Therapy of Clostridium difficile Infections. Viszeralmedizin (2014) 0.83
Guanylate cyclase C limits systemic dissemination of a murine enteric pathogen. BMC Gastroenterol (2013) 0.83
Animal models to study acute and chronic intestinal inflammation in mammals. Gut Pathog (2015) 0.83
Colonization Resistance of the Gut Microbiota against Clostridium difficile. Antibiotics (Basel) (2015) 0.82
Salmonella adhesion, invasion and cellular immune responses are differentially affected by iron concentrations in a combined in vitro gut fermentation-cell model. PLoS One (2014) 0.81
Bacterial colonization and intestinal mucosal barrier development. World J Clin Pediatr (2013) 0.81
Salmonella Typhimurium strain ATCC14028 requires H2-hydrogenases for growth in the gut, but not at systemic sites. PLoS One (2014) 0.80
Studying Vertical Microbiome Transmission from Mothers to Infants by Strain-Level Metagenomic Profiling. mSystems (2017) 0.80
Loss of sigma factor RpoN increases intestinal colonization of Vibrio parahaemolyticus in an adult mouse model. Infect Immun (2013) 0.79
Antimicrobial Use, Human Gut Microbiota and Clostridium difficile Colonization and Infection. Antibiotics (Basel) (2015) 0.78
Adult blood-feeding tsetse flies, trypanosomes, microbiota and the fluctuating environment in sub-Saharan Africa. ISME J (2014) 0.78
Evolving concepts: how diet and the intestinal microbiome act as modulators of breast malignancy. ISRN Oncol (2013) 0.77
Excretion of Host DNA in Feces Is Associated with Risk of Clostridium difficile Infection. J Immunol Res (2015) 0.77
Contrasting Ecological Processes and Functional Compositions Between Intestinal Bacterial Community in Healthy and Diseased Shrimp. Microb Ecol (2016) 0.77
The human microbiota: novel targets for hospital-acquired infections and antibiotic resistance. Ann Epidemiol (2016) 0.76
Individual-specific changes in the human gut microbiota after challenge with enterotoxigenic Escherichia coli and subsequent ciprofloxacin treatment. BMC Genomics (2016) 0.76
The Role of the Microbiota in Shaping Infectious Immunity. Trends Immunol (2016) 0.76
Bacterial and Fungal Microbiota Changes Distinguish C. difficile Infection from Other Forms of Diarrhea: Results of a Prospective Inpatient Study. Front Microbiol (2016) 0.76
Gut Microbiome: What We Do and Don't Know. Nutr Clin Pract (2015) 0.76
Rebooting the microbiome. Gut Microbes (2016) 0.75
Gut Microbiota and Intestinal Decolonization of Pathogenic Microorganisms. Chin Med J (Engl) (2016) 0.75
Conventional and alternative treatment approaches for Clostridium difficile infection. Int J Health Sci (Qassim) (2017) 0.75
Mycobacterium avium Subspecies paratuberculosis Infection Modifies Gut Microbiota under Different Dietary Conditions in a Rabbit Model. Front Microbiol (2016) 0.75
Antibiotics, gut microbiota, environment in early life and type 1 diabetes. Pharmacol Res (2017) 0.75
Quorum sensing regulators are required for metabolic fitness in Vibrio parahaemolyticus. Infect Immun (2017) 0.75
Escherichia coli and Sudden Infant Death Syndrome. Front Immunol (2015) 0.75
Importance of Salmonella Typhi-Responsive CD8+ T Cell Immunity in a Human Typhoid Fever Challenge Model. Front Immunol (2017) 0.75
Vitamin B12 Uptake by the Gut Commensal Bacteria Bacteroides thetaiotaomicron Limits the Production of Shiga Toxin by Enterohemorrhagic Escherichia coli. Toxins (Basel) (2016) 0.75
Human microbiome: From the bathroom to the bedside. World J Gastrointest Pathophysiol (2015) 0.75
Seasonal Shifts in Diet and Gut Microbiota of the American Bison (Bison bison). PLoS One (2015) 0.75
Dietary Behaviors in Psoriasis: Patient-Reported Outcomes from a U.S. National Survey. Dermatol Ther (Heidelb) (2017) 0.75
A genomic investigation of ecological differentiation between free-living and Drosophila-associated bacteria. Mol Ecol (2017) 0.75
Phages and the evolution of bacterial pathogens: from genomic rearrangements to lysogenic conversion. Microbiol Mol Biol Rev (2004) 7.93
Salmonella enterica serovar typhimurium exploits inflammation to compete with the intestinal microbiota. PLoS Biol (2007) 7.58
Pretreatment of mice with streptomycin provides a Salmonella enterica serovar Typhimurium colitis model that allows analysis of both pathogen and host. Infect Immun (2003) 6.82
Intestinal lamina propria dendritic cell subsets have different origin and functions. Immunity (2009) 5.43
Innate and adaptive immunity cooperate flexibly to maintain host-microbiota mutualism. Science (2009) 4.45
The Salmonella pathogenicity island (SPI)-2 and SPI-1 type III secretion systems allow Salmonella serovar typhimurium to trigger colitis via MyD88-dependent and MyD88-independent mechanisms. J Immunol (2005) 3.14
The role of microbiota in infectious disease. Trends Microbiol (2008) 3.11
Self-destructive cooperation mediated by phenotypic noise. Nature (2008) 3.07
The Salmonella enterica serotype typhimurium effector proteins SipA, SopA, SopB, SopD, and SopE2 act in concert to induce diarrhea in calves. Infect Immun (2002) 2.88
Enhanced CellClassifier: a multi-class classification tool for microscopy images. BMC Bioinformatics (2010) 2.84
Like will to like: abundances of closely related species can predict susceptibility to intestinal colonization by pathogenic and commensal bacteria. PLoS Pathog (2010) 2.79
Stabilization of cooperative virulence by the expression of an avirulent phenotype. Nature (2013) 2.47
Role of the Salmonella pathogenicity island 1 effector proteins SipA, SopB, SopE, and SopE2 in Salmonella enterica subspecies 1 serovar Typhimurium colitis in streptomycin-pretreated mice. Infect Immun (2004) 2.46
Flagella and chemotaxis are required for efficient induction of Salmonella enterica serovar Typhimurium colitis in streptomycin-pretreated mice. Infect Immun (2004) 2.41
Clostridium difficile toxin CDT induces formation of microtubule-based protrusions and increases adherence of bacteria. PLoS Pathog (2009) 2.29
Specific inhibition of diverse pathogens in human cells by synthetic microRNA-like oligonucleotides inferred from RNAi screens. Proc Natl Acad Sci U S A (2014) 2.25
The microbiota mediates pathogen clearance from the gut lumen after non-typhoidal Salmonella diarrhea. PLoS Pathog (2010) 2.17
A mouse model for S. typhimurium-induced enterocolitis. Trends Microbiol (2005) 2.09
Microbe sampling by mucosal dendritic cells is a discrete, MyD88-independent step in DeltainvG S. Typhimurium colitis. J Exp Med (2008) 1.92
Gut inflammation can boost horizontal gene transfer between pathogenic and commensal Enterobacteriaceae. Proc Natl Acad Sci U S A (2012) 1.90
Real-time imaging of type III secretion: Salmonella SipA injection into host cells. Proc Natl Acad Sci U S A (2005) 1.85
A Burkholderia pseudomallei type III secreted protein, BopE, facilitates bacterial invasion of epithelial cells and exhibits guanine nucleotide exchange factor activity. J Bacteriol (2003) 1.78
The S. Typhimurium effector SopE induces caspase-1 activation in stromal cells to initiate gut inflammation. Cell Host Microbe (2009) 1.74
Salmonella type III secretion effectors: pulling the host cell's strings. Curr Opin Microbiol (2006) 1.70
Motility allows S. Typhimurium to benefit from the mucosal defence. Cell Microbiol (2008) 1.69
Structural basis for the reversible activation of a Rho protein by the bacterial toxin SopE. EMBO J (2002) 1.64
The cost of virulence: retarded growth of Salmonella Typhimurium cells expressing type III secretion system 1. PLoS Pathog (2011) 1.60
Comparison of Salmonella enterica serovar Typhimurium colitis in germfree mice and mice pretreated with streptomycin. Infect Immun (2005) 1.59
Role of the Salmonella pathogenicity island 1 (SPI-1) protein InvB in type III secretion of SopE and SopE2, two Salmonella effector proteins encoded outside of SPI-1. J Bacteriol (2003) 1.54
Salmonella effectors within a single pathogenicity island are differentially expressed and translocated by separate type III secretion systems. Mol Microbiol (2002) 1.51
'Blooming' in the gut: how dysbiosis might contribute to pathogen evolution. Nat Rev Microbiol (2013) 1.45
TLR5 signaling stimulates the innate production of IL-17 and IL-22 by CD3(neg)CD127+ immune cells in spleen and mucosa. J Immunol (2010) 1.43
Salmonella Pathogenicity Island 4 encodes a giant non-fimbrial adhesin and the cognate type 1 secretion system. Cell Microbiol (2007) 1.39
The streptomycin mouse model for Salmonella diarrhea: functional analysis of the microbiota, the pathogen's virulence factors, and the host's mucosal immune response. Immunol Rev (2012) 1.30
A simple screen to identify promoters conferring high levels of phenotypic noise. PLoS Genet (2008) 1.28
RNAi screen of Salmonella invasion shows role of COPI in membrane targeting of cholesterol and Cdc42. Mol Syst Biol (2011) 1.27
The SopEPhi phage integrates into the ssrA gene of Salmonella enterica serovar Typhimurium A36 and is closely related to the Fels-2 prophage. J Bacteriol (2003) 1.26
Salmonella gut invasion involves TTSS-2-dependent epithelial traversal, basolateral exit, and uptake by epithelium-sampling lamina propria phagocytes. Cell Host Microbe (2012) 1.26
Lack of mismatch correction facilitates genome evolution in mycobacteria. Mol Microbiol (2004) 1.21
Salmonella-induced mucosal lectin RegIIIβ kills competing gut microbiota. PLoS One (2011) 1.20
Bacteriophage-encoded type III effectors in Salmonella enterica subspecies 1 serovar Typhimurium. Infect Genet Evol (2005) 1.20
Chronic Salmonella enterica serovar Typhimurium-induced colitis and cholangitis in streptomycin-pretreated Nramp1+/+ mice. Infect Immun (2006) 1.19
Phage mediated horizontal transfer of the sopE1 gene increases enteropathogenicity of Salmonella enterica serotype Typhimurium for calves. FEMS Microbiol Lett (2002) 1.19
InvB is required for type III-dependent secretion of SopA in Salmonella enterica serovar Typhimurium. J Bacteriol (2004) 1.19
Caspase-1 has both proinflammatory and regulatory properties in Helicobacter infections, which are differentially mediated by its substrates IL-1β and IL-18. J Immunol (2012) 1.19
Hierarchical effector protein transport by the Salmonella Typhimurium SPI-1 type III secretion system. PLoS One (2008) 1.18
Virulence of broad- and narrow-host-range Salmonella enterica serovars in the streptomycin-pretreated mouse model. Infect Immun (2006) 1.14
Molecular dissection of Salmonella-induced membrane ruffling versus invasion. Cell Microbiol (2009) 1.10
Near surface swimming of Salmonella Typhimurium explains target-site selection and cooperative invasion. PLoS Pathog (2012) 1.10
O-antigen-negative Salmonella enterica serovar Typhimurium is attenuated in intestinal colonization but elicits colitis in streptomycin-treated mice. Infect Immun (2009) 1.10
Two newly identified SipA domains (F1, F2) steer effector protein localization and contribute to Salmonella host cell manipulation. Mol Microbiol (2007) 1.09
Stromal IFN-γR-signaling modulates goblet cell function during Salmonella Typhimurium infection. PLoS One (2011) 1.08
Lymph node colonization dynamics after oral Salmonella Typhimurium infection in mice. PLoS Pathog (2013) 1.00
Accelerated type III secretion system 2-dependent enteropathogenesis by a Salmonella enterica serovar enteritidis PT4/6 strain. Infect Immun (2009) 0.96
Salmonella enterica serovar Typhimurium binds to HeLa cells via Fim-mediated reversible adhesion and irreversible type three secretion system 1-mediated docking. Infect Immun (2010) 0.96
The chaperone binding domain of SopE inhibits transport via flagellar and SPI-1 TTSS in the absence of InvB. Mol Microbiol (2006) 0.93
Characterization of effector proteins translocated via the SPI1 type III secretion system of Salmonella typhimurium. Int J Med Microbiol (2002) 0.93
Salmonella transiently reside in luminal neutrophils in the inflamed gut. PLoS One (2012) 0.92
In macrophages, caspase-1 activation by SopE and the type III secretion system-1 of S. typhimurium can proceed in the absence of flagellin. PLoS One (2010) 0.91
Amino acids of the bacterial toxin SopE involved in G nucleotide exchange on Cdc42. J Biol Chem (2003) 0.91
Salmonella typhimurium diarrhea: switching the mucosal epithelium from homeostasis to defense. Curr Opin Immunol (2011) 0.90
The dual role of wild phages for horizontal gene transfer among Salmonella strains. Berl Munch Tierarztl Wochenschr (2002) 0.90
IL-17A/F-signaling does not contribute to the initial phase of mucosal inflammation triggered by S. Typhimurium. PLoS One (2010) 0.89
Peroral ciprofloxacin therapy impairs the generation of a protective immune response in a mouse model for Salmonella enterica serovar Typhimurium diarrhea, while parenteral ceftriaxone therapy does not. Antimicrob Agents Chemother (2012) 0.89
Dangerous liaisons between a microbe and the prion protein. J Exp Med (2003) 0.89
Bacterial colitis increases susceptibility to oral prion disease. J Infect Dis (2009) 0.89
Salmonella pathogenicity island 2-mediated overexpression of chimeric SspH2 proteins for simultaneous induction of antigen-specific CD4 and CD8 T cells. Infect Immun (2005) 0.88
The bactericidal activity of the C-type lectin RegIIIβ against Gram-negative bacteria involves binding to lipid A. J Biol Chem (2012) 0.87
Impact of Salmonella Typhimurium DT104 virulence factors invC and sseD on the onset, clinical course, colonization patterns and immune response of porcine salmonellosis. Vet Microbiol (2007) 0.86
PEGylation of bacteriophages increases blood circulation time and reduces T-helper type 1 immune response. Microb Biotechnol (2008) 0.86
Caspase-1 activation via Rho GTPases: a common theme in mucosal infections? PLoS Pathog (2010) 0.85
A novel phage element of Salmonella enterica serovar Enteritidis P125109 contributes to accelerated type III secretion system 2-dependent early inflammation kinetics in a mouse colitis model. Infect Immun (2012) 0.85
NADPH oxidase deficient mice develop colitis and bacteremia upon infection with normally avirulent, TTSS-1- and TTSS-2-deficient Salmonella Typhimurium. PLoS One (2013) 0.84
Deletion of invH gene in Salmonella enterica serovar Typhimurium limits the secretion of Sip effector proteins. Microbes Infect (2012) 0.84
Live attenuated S. Typhimurium vaccine with improved safety in immuno-compromised mice. PLoS One (2012) 0.83
Salmonella pathogenicity island 1 differentially modulates bacterial entry to dendritic and non-phagocytic cells. Immunology (2010) 0.83
Absence of poly(ADP-ribose) polymerase 1 delays the onset of Salmonella enterica serovar Typhimurium-induced gut inflammation. Infect Immun (2010) 0.83
Simultaneous analysis of large-scale RNAi screens for pathogen entry. BMC Genomics (2014) 0.83
Stability of gene rankings from RNAi screens. Bioinformatics (2012) 0.81
Subpopulation-specific metabolic pathway usage in mixed cultures as revealed by reporter protein-based 13C analysis. Appl Environ Microbiol (2011) 0.80
Roles of spvB and spvC in S. Typhimurium colitis via the alternative pathway. Int J Med Microbiol (2010) 0.78
Outer membrane permeabilization is an essential step in the killing of gram-negative bacteria by the lectin RegIIIβ. PLoS One (2013) 0.77
Bartonella henselae engages inside-out and outside-in signaling by integrin β1 and talin1 during invasome-mediated bacterial uptake. J Cell Sci (2011) 0.77
Quantitative insights into actin rearrangements and bacterial target site selection from Salmonella Typhimurium infection of micropatterned cells. Cell Microbiol (2013) 0.77
The Salmonella Typhimurium effector protein SopE transiently localizes to the early SCV and contributes to intracellular replication. Cell Microbiol (2014) 0.76
Correction: Granulocytes Impose a Tight Bottleneck upon the Gut Luminal Pathogen Population during Salmonella Typhimurium Colitis. PLoS Pathog (2015) 0.75
Evolution of bacterial virulence. FEMS Microbiol Rev (2017) 0.75