Published in J Biol Chem on July 18, 2011
Lipoic acid metabolism of Plasmodium--a suitable drug target. Curr Pharm Des (2012) 0.82
The role of the Saccharomyces cerevisiae lipoate protein ligase homologue, Lip3, in lipoic acid synthesis. Yeast (2013) 0.79
Assembly of Lipoic Acid on Its Cognate Enzymes: an Extraordinary and Essential Biosynthetic Pathway. Microbiol Mol Biol Rev (2016) 0.78
A novel lipoate attachment enzyme is shared by Plasmodium and Chlamydia species. Mol Microbiol (2017) 0.77
The Streptomyces coelicolor lipoate-protein ligase is a circularly permuted version of the Escherichia coli enzyme composed of discrete interacting domains. J Biol Chem (2015) 0.75
Staphylococcus aureus Tissue Infection During Sepsis Is Supported by Differential Use of Bacterial or Host-Derived Lipoic Acid. PLoS Pathog (2016) 0.75
Listeria monocytogenes cytosolic metabolism promotes replication, survival and evasion of innate immunity. Cell Microbiol (2017) 0.75
Quantitative film detection of 3H and 14C in polyacrylamide gels by fluorography. Eur J Biochem (1975) 56.72
The Pfam protein families database. Nucleic Acids Res (2009) 37.98
Dendroscope: An interactive viewer for large phylogenetic trees. BMC Bioinformatics (2007) 11.03
Manganese import is a key element of the OxyR response to hydrogen peroxide in Escherichia coli. Mol Microbiol (2009) 3.34
Nutritional immunity beyond iron: a role for manganese and zinc. Curr Opin Chem Biol (2009) 2.69
A family of LIC vectors for high-throughput cloning and purification of proteins. Methods Mol Biol (2009) 2.30
Automation of protein purification for structural genomics. J Struct Funct Genomics (2004) 2.17
Assembly of the covalent linkage between lipoic acid and its cognate enzymes. Chem Biol (2003) 2.11
Identification of the gene encoding lipoate-protein ligase A of Escherichia coli. Molecular cloning and characterization of the lplA gene and gene product. J Biol Chem (1994) 1.73
Function, attachment and synthesis of lipoic acid in Escherichia coli. Adv Microb Physiol (2005) 1.66
Lipoic acid metabolism in Escherichia coli: the lplA and lipB genes define redundant pathways for ligation of lipoyl groups to apoprotein. J Bacteriol (1995) 1.64
Listeria intracellular growth and virulence require host-derived lipoic acid. Science (2003) 1.50
Lipoic acid synthesis and attachment in yeast mitochondria. J Biol Chem (2009) 1.18
The Thermoplasma acidophilum LplA-LplB complex defines a new class of bipartite lipoate-protein ligases. J Biol Chem (2009) 1.07
LIPOAMIDASE. J Biol Chem (1963) 1.04
Expression cloning and demonstration of Enterococcus faecalis lipoamidase (pyruvate dehydrogenase inactivase) as a Ser-Ser-Lys triad amidohydrolase. J Biol Chem (2004) 1.01
LplA1-dependent utilization of host lipoyl peptides enables Listeria cytosolic growth and virulence. Mol Microbiol (2007) 1.01
A novel amidotransferase required for lipoic acid cofactor assembly in Bacillus subtilis. Mol Microbiol (2011) 0.97
A novel two-gene requirement for the octanoyltransfer reaction of Bacillus subtilis lipoic acid biosynthesis. Mol Microbiol (2011) 0.96
Lipoic acid synthesis: a new family of octanoyltransferases generally annotated as lipoate protein ligases. Biochemistry (2010) 0.94
Detection of bacterial lipoic acid. A modified gas-chromatographic-mass-spectrometric procedure. Biochem J (1989) 0.93
Investigation of the mechanisms by which Listeria monocytogenes grows in porcine gallbladder bile. Infect Immun (2010) 0.91
Crystal structure of bovine lipoyltransferase in complex with lipoyl-AMP. J Mol Biol (2007) 0.90
Generation of branched-chain fatty acids through lipoate-dependent metabolism facilitates intracellular growth of Listeria monocytogenes. J Bacteriol (2009) 0.89
Protein-protein interactions in assembly of lipoic acid on the 2-oxoacid dehydrogenases of aerobic metabolism. J Biol Chem (2011) 0.84
Acyl group transfer by proteases forming an acylenzyme intermediate: kinetic model analysis (including hydrolysis of acylenzyme- nucleophile complex). J Theor Biol (1989) 0.82
Recombinant expression and evaluation of the lipoyl domains of the dihydrolipoyl acetyltransferase component of the human pyruvate dehydrogenase complex. Arch Biochem Biophys (1995) 0.81
Estimation of plasma free fatty acids as the trimethylsilyl (TMS) esters. Anal Biochem (1976) 0.81
Caspase-11 protects against bacteria that escape the vacuole. Science (2013) 4.01
Assembly of the covalent linkage between lipoic acid and its cognate enzymes. Chem Biol (2003) 2.11
The Enzyme Function Initiative. Biochemistry (2011) 1.87
Transcriptional patterns in both host and bacterium underlie a daily rhythm of anatomical and metabolic change in a beneficial symbiosis. Proc Natl Acad Sci U S A (2010) 1.82
Biotin synthase is catalytic in vivo, but catalysis engenders destruction of the protein. Chem Biol (2005) 1.73
The enigmatic Escherichia coli fadE gene is yafH. J Bacteriol (2002) 1.63
Escherichia coli unsaturated fatty acid synthesis: complex transcription of the fabA gene and in vivo identification of the essential reaction catalyzed by FabB. J Biol Chem (2009) 1.63
Biotin synthesis begins by hijacking the fatty acid synthetic pathway. Nat Chem Biol (2010) 1.57
Long-term and homogeneous regulation of the Escherichia coli araBAD promoter by use of a lactose transporter of relaxed specificity. Proc Natl Acad Sci U S A (2002) 1.57
Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS. Proc Natl Acad Sci U S A (2014) 1.54
Innate recognition of intracellular bacteria. Curr Opin Immunol (2006) 1.50
Vibrio cholerae FabV defines a new class of enoyl-acyl carrier protein reductase. J Biol Chem (2007) 1.46
Discovery of new enzymes and metabolic pathways by using structure and genome context. Nature (2013) 1.46
Beta-ketoacyl-acyl carrier protein synthase III (FabH) is essential for bacterial fatty acid synthesis. J Biol Chem (2003) 1.45
TBK1 protects vacuolar integrity during intracellular bacterial infection. PLoS Pathog (2007) 1.43
A new Escherichia coli metabolic competency: growth on fatty acids by a novel anaerobic beta-oxidation pathway. Mol Microbiol (2003) 1.42
Triclosan resistance of Pseudomonas aeruginosa PAO1 is due to FabV, a triclosan-resistant enoyl-acyl carrier protein reductase. Antimicrob Agents Chemother (2009) 1.41
The biotin repressor: modulation of allostery by corepressor analogs. J Mol Biol (2004) 1.39
The soluble acyl-acyl carrier protein synthetase of Vibrio harveyi B392 is a member of the medium chain acyl-CoA synthetase family. Biochemistry (2006) 1.39
XIAP regulates cytosol-specific innate immunity to Listeria infection. PLoS Pathog (2008) 1.36
Complex binding of the FabR repressor of bacterial unsaturated fatty acid biosynthesis to its cognate promoters. Mol Microbiol (2011) 1.29
Closing in on complete pathways of biotin biosynthesis. Mol Biosyst (2011) 1.26
The Burkholderia cenocepacia BDSF quorum sensing fatty acid is synthesized by a bifunctional crotonase homologue having both dehydratase and thioesterase activities. Mol Microbiol (2012) 1.23
Promiscuous protein biotinylation by Escherichia coli biotin protein ligase. Protein Sci (2004) 1.22
A nucleosidase required for in vivo function of the S-adenosyl-L-methionine radical enzyme, biotin synthase. Chem Biol (2005) 1.22
Mechanism of a prototypical synthetic membrane-active antimicrobial: Efficient hole-punching via interaction with negative intrinsic curvature lipids. Proc Natl Acad Sci U S A (2008) 1.20
A new member of the Escherichia coli fad regulon: transcriptional regulation of fadM (ybaW). J Bacteriol (2009) 1.19
The biotin carboxylase-biotin carboxyl carrier protein complex of Escherichia coli acetyl-CoA carboxylase. J Biol Chem (2003) 1.18
Functional replacement of the FabA and FabB proteins of Escherichia coli fatty acid synthesis by Enterococcus faecalis FabZ and FabF homologues. J Biol Chem (2004) 1.18
Unexpected functional diversity among FadR fatty acid transcriptional regulatory proteins. J Biol Chem (2005) 1.17
Intracellular innate resistance to bacterial pathogens. Cell Microbiol (2006) 1.17
In vivo functional analyses of the type II acyl carrier proteins of fatty acid biosynthesis. J Biol Chem (2007) 1.16
Expression of Vibrio harveyi acyl-ACP synthetase allows efficient entry of exogenous fatty acids into the Escherichia coli fatty acid and lipid A synthetic pathways. Biochemistry (2010) 1.15
The reaction of LipB, the octanoyl-[acyl carrier protein]:protein N-octanoyltransferase of lipoic acid synthesis, proceeds through an acyl-enzyme intermediate. Biochemistry (2005) 1.14
The beta-oxidation systems of Escherichia coli and Salmonella enterica are not functionally equivalent. J Bacteriol (2006) 1.13
Overlapping repressor binding sites result in additive regulation of Escherichia coli FadH by FadR and ArcA. J Bacteriol (2010) 1.13
The Escherichia coli lipB gene encodes lipoyl (octanoyl)-acyl carrier protein:protein transferase. J Bacteriol (2003) 1.11
The Mycobacterium tuberculosis LipB enzyme functions as a cysteine/lysine dyad acyltransferase. Proc Natl Acad Sci U S A (2006) 1.11
The Vibrio cholerae fatty acid regulatory protein, FadR, represses transcription of plsB, the gene encoding the first enzyme of membrane phospholipid biosynthesis. Mol Microbiol (2011) 1.10
Isolation and characterization of beta-ketoacyl-acyl carrier protein reductase (fabG) mutants of Escherichia coli and Salmonella enterica serovar Typhimurium. J Bacteriol (2004) 1.09
Burkholderia BcpA mediates biofilm formation independently of interbacterial contact-dependent growth inhibition. Mol Microbiol (2013) 1.09
The Thermoplasma acidophilum LplA-LplB complex defines a new class of bipartite lipoate-protein ligases. J Biol Chem (2009) 1.07
Expression of two Escherichia coli acetyl-CoA carboxylase subunits is autoregulated. J Biol Chem (2003) 1.06
Structure of the enzyme-acyl carrier protein (ACP) substrate gatekeeper complex required for biotin synthesis. Proc Natl Acad Sci U S A (2012) 1.03
Expression cloning and demonstration of Enterococcus faecalis lipoamidase (pyruvate dehydrogenase inactivase) as a Ser-Ser-Lys triad amidohydrolase. J Biol Chem (2004) 1.01
LplA1-dependent utilization of host lipoyl peptides enables Listeria cytosolic growth and virulence. Mol Microbiol (2007) 1.01
The Escherichia coli fadK (ydiD) gene encodes an anerobically regulated short chain acyl-CoA synthetase. J Biol Chem (2004) 1.01
Branched-chain fatty acids promote Listeria monocytogenes intracellular infection and virulence. Infect Immun (2010) 0.98
Scavenging of cytosolic octanoic acid by mutant LplA lipoate ligases allows growth of Escherichia coli strains lacking the LipB octanoyltransferase of lipoic acid synthesis. J Bacteriol (2009) 0.98
A novel amidotransferase required for lipoic acid cofactor assembly in Bacillus subtilis. Mol Microbiol (2011) 0.97
Membrane damage during Listeria monocytogenes infection triggers a caspase-7 dependent cytoprotective response. PLoS Pathog (2012) 0.97
Homeostatic maintenance of pathogen-containing vacuoles requires TBK1-dependent regulation of aquaporin-1. Cell Microbiol (2008) 0.97
A novel two-gene requirement for the octanoyltransfer reaction of Bacillus subtilis lipoic acid biosynthesis. Mol Microbiol (2011) 0.96
Roles of small laccases from Streptomyces in lignin degradation. Biochemistry (2014) 0.95
Crosstalk of Escherichia coli FadR with global regulators in expression of fatty acid transport genes. PLoS One (2012) 0.95
The enigmatic acyl carrier protein phosphodiesterase of Escherichia coli: genetic and enzymological characterization. J Biol Chem (2005) 0.95
Haemophilus influenzae Rd lacks a stringently conserved fatty acid biosynthetic enzyme and thermal control of membrane lipid composition. J Bacteriol (2003) 0.95
The Lactococcus lactis FabF fatty acid synthetic enzyme can functionally replace both the FabB and FabF proteins of Escherichia coli and the FabH protein of Lactococcus lactis. Arch Microbiol (2008) 0.95
Antibacterial activity of N-pentylpantothenamide is due to inhibition of coenzyme a synthesis. Antimicrob Agents Chemother (2010) 0.94
Lipoic acid synthesis: a new family of octanoyltransferases generally annotated as lipoate protein ligases. Biochemistry (2010) 0.94
Profligate biotin synthesis in α-proteobacteria - a developing or degenerating regulatory system? Mol Microbiol (2013) 0.94
Altered regulation of Escherichia coli biotin biosynthesis in BirA superrepressor mutant strains. J Bacteriol (2011) 0.94
Only one of the two annotated Lactococcus lactis fabG genes encodes a functional beta-ketoacyl-acyl carrier protein reductase. Biochemistry (2004) 0.94
Coordinate expression of the acetyl coenzyme A carboxylase genes, accB and accC, is necessary for normal regulation of biotin synthesis in Escherichia coli. J Bacteriol (2006) 0.93
Xanthomonas campestris RpfB is a fatty Acyl-CoA ligase required to counteract the thioesterase activity of the RpfF diffusible signal factor (DSF) synthase. Mol Microbiol (2014) 0.93
The switch regulating transcription of the Escherichia coli biotin operon does not require extensive protein-protein interactions. Chem Biol (2010) 0.91
Gene-specific random mutagenesis of Escherichia coli in vivo: isolation of temperature-sensitive mutations in the acyl carrier protein of fatty acid synthesis. J Bacteriol (2006) 0.91
The two functional enoyl-acyl carrier protein reductases of Enterococcus faecalis do not mediate triclosan resistance. MBio (2013) 0.91
A Francisella virulence factor catalyses an essential reaction of biotin synthesis. Mol Microbiol (2013) 0.90
The BioC O-methyltransferase catalyzes methyl esterification of malonyl-acyl carrier protein, an essential step in biotin synthesis. J Biol Chem (2012) 0.90
Functions of the Clostridium acetobutylicium FabF and FabZ proteins in unsaturated fatty acid biosynthesis. BMC Microbiol (2009) 0.90
Fatty acids regulate stress resistance and virulence factor production for Listeria monocytogenes. J Bacteriol (2012) 0.89
Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes. Biochemistry (2015) 0.88
A genome rearrangement has orphaned the Escherichia coli K-12 AcpT phosphopantetheinyl transferase from its cognate Escherichia coli O157:H7 substrates. Mol Microbiol (2006) 0.86
Intein-mediated cyclization of bacterial acyl carrier protein stabilizes its folded conformation but does not abolish function. J Biol Chem (2010) 0.86
Regulation of bacterial pathogenesis by intestinal short-chain Fatty acids. Adv Appl Microbiol (2013) 0.85
The wing of a winged helix-turn-helix transcription factor organizes the active site of BirA, a bifunctional repressor/ligase. J Biol Chem (2013) 0.85
Protein-protein interactions in assembly of lipoic acid on the 2-oxoacid dehydrogenases of aerobic metabolism. J Biol Chem (2011) 0.84
Remarkable diversity in the enzymes catalyzing the last step in synthesis of the pimelate moiety of biotin. PLoS One (2012) 0.84
Dimerization of the bacterial biotin carboxylase subunit is required for acetyl coenzyme A carboxylase activity in vivo. J Bacteriol (2011) 0.84
Dephospho-CoA kinase provides a rapid and sensitive radiochemical assay for coenzyme A and its thioesters. Anal Biochem (2007) 0.84
More than a pore: the cellular response to cholesterol-dependent cytolysins. Toxins (Basel) (2013) 0.83
Genetic interaction between the Escherichia coli AcpT phosphopantetheinyl transferase and the YejM inner membrane protein. Genetics (2008) 0.83
Discovery of a cAMP deaminase that quenches cyclic AMP-dependent regulation. ACS Chem Biol (2013) 0.83
Acyl carrier protein phosphodiesterase (AcpH) of Escherichia coli is a non-canonical member of the HD phosphatase/phosphodiesterase family. Biochemistry (2007) 0.82
Prediction and biochemical demonstration of a catabolic pathway for the osmoprotectant proline betaine. MBio (2014) 0.82
A small molecule deubiquitinase inhibitor increases localization of inducible nitric oxide synthase to the macrophage phagosome and enhances bacterial killing. Infect Immun (2011) 0.82
Chromosomal amplification of the Escherichia coli lipB region confers high-level resistance to selenolipoic acid. J Bacteriol (2002) 0.82
Only one of the five Ralstonia solanacearum long-chain 3-ketoacyl-acyl carrier protein synthase homologues functions in fatty acid synthesis. Appl Environ Microbiol (2011) 0.81
Evolution of a new function in an esterase: simple amino acid substitutions enable the activity present in the larger paralog, BioH. Protein Eng Des Sel (2012) 0.80
FabQ, a dual-function dehydratase/isomerase, circumvents the last step of the classical fatty acid synthesis cycle. Chem Biol (2013) 0.80
Stabilization of the biotinoyl domain of Escherichia coli acetyl-CoA carboxylase by interactions between the attached biotin and the protruding "thumb" structure. J Biol Chem (2002) 0.80
Two-Carbon Compounds and Fatty Acids as Carbon Sources. Ecosal Plus (2005) 0.79
The role of the Saccharomyces cerevisiae lipoate protein ligase homologue, Lip3, in lipoic acid synthesis. Yeast (2013) 0.79
Remarkable structural variation within fatty acid megasynthases. Nat Chem Biol (2006) 0.79
Innate-like CD4 T cells selected by thymocytes suppress adaptive immune responses against bacterial infections. Open J Immunol (2011) 0.79
In vivo resolution of conflicting in vitro results: synthesis of biotin from dethiobiotin does not require pyridoxal phosphate. Chem Biol (2007) 0.77
Inefficient translation renders the Enterococcus faecalis fabK enoyl-acyl carrier protein reductase phenotypically cryptic. J Bacteriol (2013) 0.77
Never fat or gaunt. Dev Cell (2003) 0.77