Helen Walden

Author PubWeight™ 23.53‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65. Open Biol 2012 3.42
2 Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases. Mol Cell 2009 2.84
3 Autoregulation of Parkin activity through its ubiquitin-like domain. EMBO J 2011 2.75
4 Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations. Nat Immunol 2005 2.44
5 Ubiquitin signalling in DNA replication and repair. Nat Rev Mol Cell Biol 2010 2.41
6 A molecular explanation for the recessive nature of parkin-linked Parkinson's disease. Nat Commun 2013 1.51
7 Structural analysis of Escherichia coli ThiF. J Mol Biol 2005 1.28
8 Hydrophobic, aromatic, and electrostatic interactions play a central role in amyloid fibril formation and stability. Biochemistry 2011 1.26
9 The structural basis for substrate promiscuity in 2-keto-3-deoxygluconate aldolase from the Entner-Doudoroff pathway in Sulfolobus solfataricus. J Biol Chem 2004 1.23
10 The structure of the catalytic subunit FANCL of the Fanconi anemia core complex. Nat Struct Mol Biol 2010 1.23
11 Ubiquitin-like protein activation. Oncogene 2004 1.18
12 Structural analysis of human FANCL, the E3 ligase in the Fanconi anemia pathway. J Biol Chem 2011 0.97
13 Small, N-terminal tags activate Parkin E3 ubiquitin ligase activity by disrupting its autoinhibited conformation. PLoS One 2012 0.95
14 Towards a molecular understanding of the fanconi anemia core complex. Anemia 2012 0.84
15 Molecular replacements. Acta Crystallogr D Biol Crystallogr 2013 0.75