Published in J Biol Chem on July 20, 2011
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Stress and DNA repair biology of the Fanconi anemia pathway. Blood (2014) 0.99
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FANCL ubiquitinates β-catenin and enhances its nuclear function. Blood (2012) 0.89
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The Fanconi anemia pathway and DNA interstrand cross-link repair. Protein Cell (2011) 0.83
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The PI3K/Akt1 pathway enhances steady-state levels of FANCL. Mol Biol Cell (2013) 0.78
Mechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3. Biochem J (2016) 0.75
Fanconi anemia pathway defects in inherited and sporadic cancers. Transl Pediatr (2014) 0.75
The Simple Chordate Ciona intestinalis Has a Reduced Complement of Genes Associated with Fanconi Anemia. Evol Bioinform Online (2016) 0.75
The FA Core Complex Contains a Homo-dimeric Catalytic Module for the Symmetric Mono-ubiquitination of FANCI-FANCD2. Cell Rep (2016) 0.75
Features and development of Coot. Acta Crystallogr D Biol Crystallogr (2010) 89.46
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PHENIX: building new software for automated crystallographic structure determination. Acta Crystallogr D Biol Crystallogr (2002) 53.61
Integration, scaling, space-group assignment and post-refinement. Acta Crystallogr D Biol Crystallogr (2010) 23.35
PDB2PQR: an automated pipeline for the setup of Poisson-Boltzmann electrostatics calculations. Nucleic Acids Res (2004) 11.53
MOLPROBITY: structure validation and all-atom contact analysis for nucleic acids and their complexes. Nucleic Acids Res (2004) 9.86
Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway. Mol Cell (2001) 8.99
Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases. Cell (2000) 7.82
Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair. Cell (2007) 6.68
The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair. Science (2009) 4.85
A novel ubiquitin ligase is deficient in Fanconi anemia. Nat Genet (2003) 4.79
RF cloning: a restriction-free method for inserting target genes into plasmids. J Biochem Biophys Methods (2006) 3.57
FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway. Nat Struct Mol Biol (2008) 3.22
Ku70 corrupts DNA repair in the absence of the Fanconi anemia pathway. Science (2010) 2.67
The vertebrate Hef ortholog is a component of the Fanconi anemia tumor-suppressor pathway. Nat Struct Mol Biol (2005) 2.55
UBE2T is the E2 in the Fanconi anemia pathway and undergoes negative autoregulation. Mol Cell (2006) 2.51
FANCI is a second monoubiquitinated member of the Fanconi anemia pathway. Nat Struct Mol Biol (2007) 2.47
Mechanistic insight into site-restricted monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI. Mol Cell (2008) 2.45
Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13. Nat Struct Biol (2001) 2.34
Positional cloning of a novel Fanconi anemia gene, FANCD2. Mol Cell (2001) 2.33
The Fanconi anaemia gene FANCF encodes a novel protein with homology to ROM. Nat Genet (2000) 1.64
Web servers and services for electrostatics calculations with APBS and PDB2PQR. J Comput Chem (2011) 1.45
RAD18-mediated ubiquitination of PCNA activates the Fanconi anemia DNA repair network. J Cell Biol (2010) 1.42
The fanconi anemia proteins FANCA and FANCG stabilize each other and promote the nuclear accumulation of the Fanconi anemia complex. Blood (2000) 1.39
Direct interactions of the five known Fanconi anaemia proteins suggest a common functional pathway. Hum Mol Genet (2001) 1.34
Fanconi's anemia and malignancies. Am J Hematol (1996) 1.32
The structure of the catalytic subunit FANCL of the Fanconi anemia core complex. Nat Struct Mol Biol (2010) 1.23
Anatomy of the E2 ligase fold: implications for enzymology and evolution of ubiquitin/Ub-like protein conjugation. J Struct Biol (2008) 1.19
Xpf and not the Fanconi anaemia proteins or Rev3 accounts for the extreme resistance to cisplatin in Dictyostelium discoideum. PLoS Genet (2009) 1.19
The WD40 repeats of FANCL are required for Fanconi anemia core complex assembly. J Biol Chem (2006) 1.17
Solution structure of the RWD domain of the mouse GCN2 protein. Protein Sci (2004) 1.13
A test for Fanconi's anemia. Blood (1987) 1.04
Drosophila homologs of FANCD2 and FANCL function in DNA repair. DNA Repair (Amst) (2006) 1.02
Strategies for DNA interstrand crosslink repair: insights from worms, flies, frogs, and slime molds. Environ Mol Mutagen (2010) 1.02
The Fanconi anemia gene network is conserved from zebrafish to human. Gene (2006) 0.90
Regulated binding of the Fanconi anemia proteins, FANCA and FANCC. Blood (1999) 0.77
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65. Open Biol (2012) 3.42
Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases. Mol Cell (2009) 2.84
Autoregulation of Parkin activity through its ubiquitin-like domain. EMBO J (2011) 2.75
Recognition of an intra-chain tandem 14-3-3 binding site within PKCepsilon. EMBO Rep (2009) 2.55
Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations. Nat Immunol (2005) 2.44
Ubiquitin signalling in DNA replication and repair. Nat Rev Mol Cell Biol (2010) 2.41
Structure of a bacterial voltage-gated sodium channel pore reveals mechanisms of opening and closing. Nat Commun (2012) 2.01
14-3-3 proteins interact with a hybrid prenyl-phosphorylation motif to inhibit G proteins. Cell (2013) 1.90
A molecular explanation for the recessive nature of parkin-linked Parkinson's disease. Nat Commun (2013) 1.51
Structural analysis of Escherichia coli ThiF. J Mol Biol (2005) 1.28
Hydrophobic, aromatic, and electrostatic interactions play a central role in amyloid fibril formation and stability. Biochemistry (2011) 1.26
The structure of the catalytic subunit FANCL of the Fanconi anemia core complex. Nat Struct Mol Biol (2010) 1.23
The structural basis for substrate promiscuity in 2-keto-3-deoxygluconate aldolase from the Entner-Doudoroff pathway in Sulfolobus solfataricus. J Biol Chem (2004) 1.23
Ubiquitin-like protein activation. Oncogene (2004) 1.18
Clostridium absonum alpha-toxin: new insights into clostridial phospholipase C substrate binding and specificity. J Mol Biol (2003) 1.05
Molecular architecture and functional analysis of NetB, a pore-forming toxin from Clostridium perfringens. J Biol Chem (2012) 0.97
Small, N-terminal tags activate Parkin E3 ubiquitin ligase activity by disrupting its autoinhibited conformation. PLoS One (2012) 0.95
Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design. J Mol Biol (2009) 0.93
Selective and potent proteomimetic inhibitors of intracellular protein-protein interactions. Angew Chem Int Ed Engl (2015) 0.92
Crystal structure of the human, FIC-domain containing protein HYPE and implications for its functions. Structure (2014) 0.92
Adenosine-binding motif mimicry and cellular effects of a thieno[2,3-d]pyrimidine-based chemical inhibitor of atypical protein kinase C isoenzymes. Biochem J (2013) 0.88
Clostridium perfringens epsilon toxin H149A mutant as a platform for receptor binding studies. Protein Sci (2013) 0.85
Orthogonal functionalisation of α-helix mimetics. Org Biomol Chem (2014) 0.84
Towards a molecular understanding of the fanconi anemia core complex. Anemia (2012) 0.84
Crystal structures of the human Dysferlin inner DysF domain. BMC Struct Biol (2014) 0.80
A cancer-associated mutation in atypical protein kinase Cι occurs in a substrate-specific recruitment motif. Sci Signal (2013) 0.80
Multivalent helix mimetics for PPI-inhibition. Org Biomol Chem (2015) 0.77
Molecular replacements. Acta Crystallogr D Biol Crystallogr (2013) 0.75