Published in Blood on July 27, 2011
Marginal zone B cells: virtues of innate-like antibody-producing lymphocytes. Nat Rev Immunol (2013) 2.49
The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development. J Exp Med (2012) 1.90
Akt and mTOR in B Cell Activation and Differentiation. Front Immunol (2012) 1.16
Whole-exome sequencing in splenic marginal zone lymphoma reveals mutations in genes involved in marginal zone differentiation. Leukemia (2013) 1.14
Requirement for Rictor in homeostasis and function of mature B lymphoid cells. Blood (2013) 1.09
KLF2 mutation is the most frequent somatic change in splenic marginal zone lymphoma and identifies a subset with distinct genotype. Leukemia (2014) 1.05
IRF4 controls the positioning of mature B cells in the lymphoid microenvironments by regulating NOTCH2 expression and activity. J Exp Med (2013) 0.95
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Transitional B cells commit to marginal zone B cell fate by Taok3-mediated surface expression of ADAM10. Nat Immunol (2017) 0.81
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Notch-regulated periphery B cell differentiation involves suppression of E protein function. J Immunol (2013) 0.76
The genetic landscape of dural marginal zone lymphomas. Oncotarget (2016) 0.76
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The splenic marginal zone shapes the phenotype of leukemia B cells and facilitates their niche-specific retention and survival. Oncoimmunology (2017) 0.75
Regulation of the germinal center response by microRNA-155. Science (2007) 12.25
Nuclear signalling by tumour-associated antigen EpCAM. Nat Cell Biol (2009) 4.05
Gene targeting by homologous recombination in mouse zygotes mediated by zinc-finger nucleases. Proc Natl Acad Sci U S A (2010) 3.90
Canonical NF-kappaB activity, dispensable for B cell development, replaces BAFF-receptor signals and promotes B cell proliferation upon activation. Immunity (2006) 3.74
The emerging role of EpCAM in cancer and stem cell signaling. Cancer Res (2009) 3.25
TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2. Nature (2002) 3.21
Yin Yang 1 is a critical regulator of B-cell development. Genes Dev (2007) 3.06
Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2. EMBO Rep (2008) 3.03
Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress. Nat Neurosci (2003) 2.79
Rapid generation of inducible mouse mutants. Nucleic Acids Res (2003) 2.77
The carcinoma-associated antigen EpCAM upregulates c-myc and induces cell proliferation. Oncogene (2004) 2.67
Direct production of mouse disease models by embryo microinjection of TALENs and oligodeoxynucleotides. Proc Natl Acad Sci U S A (2013) 2.63
TNF family member B cell-activating factor (BAFF) receptor-dependent and -independent roles for BAFF in B cell physiology. J Immunol (2004) 2.51
Inhibition of transcription factor NF-kappaB in the central nervous system ameliorates autoimmune encephalomyelitis in mice. Nat Immunol (2006) 2.48
Canonical Notch2 signaling determines biliary cell fates of embryonic hepatoblasts and adult hepatocytes independent of Hes1. Hepatology (2013) 2.34
Liver-specific inactivation of Notch2, but not Notch1, compromises intrahepatic bile duct development in mice. Hepatology (2008) 2.21
Inducible gene deletion in astroglia and radial glia--a valuable tool for functional and lineage analysis. Glia (2006) 2.19
B cells lacking the tumor suppressor TNFAIP3/A20 display impaired differentiation and hyperactivation and cause inflammation and autoimmunity in aged mice. Blood (2010) 2.17
Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis. J Exp Med (2010) 2.15
Enhanced efficiency through nuclear localization signal fusion on phage PhiC31-integrase: activity comparison with Cre and FLPe recombinase in mammalian cells. Nucleic Acids Res (2002) 2.14
Phosphatidylcholine synthesis for lipid droplet expansion is mediated by localized activation of CTP:phosphocholine cytidylyltransferase. Cell Metab (2011) 2.14
IkappaB kinase signaling is essential for maintenance of mature B cells. J Exp Med (2002) 1.93
Constitutive canonical NF-κB activation cooperates with disruption of BLIMP1 in the pathogenesis of activated B cell-like diffuse large cell lymphoma. Cancer Cell (2010) 1.85
Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma. Proc Natl Acad Sci U S A (2010) 1.84
B-cell depletion reactivates B lymphopoiesis in the BM and rejuvenates the B lineage in aging. Blood (2011) 1.82
Essential role for IkappaB kinase beta in remodeling Carma1-Bcl10-Malt1 complexes upon T cell activation. Mol Cell (2006) 1.78
A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis. Nat Genet (2011) 1.78
Hierarchy of Notch-Delta interactions promoting T cell lineage commitment and maturation. J Exp Med (2007) 1.73
Protein kinase c-β-dependent activation of NF-κB in stromal cells is indispensable for the survival of chronic lymphocytic leukemia B cells in vivo. Cancer Cell (2013) 1.68
Hepatic NF-kappa B essential modulator deficiency prevents obesity-induced insulin resistance but synergizes with high-fat feeding in tumorigenesis. Proc Natl Acad Sci U S A (2008) 1.64
Glutamatergic and dopaminergic neurons mediate anxiogenic and anxiolytic effects of CRHR1. Science (2011) 1.64
A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKgamma to dampen the host NF-kappaB-mediated inflammatory response. Nat Cell Biol (2009) 1.60
The functional annotation of mammalian genomes: the challenge of phenotyping. Annu Rev Genet (2009) 1.54
Mechanisms of proinflammatory cytokine-induced biphasic NF-kappaB activation. Mol Cell (2003) 1.49
NIK overexpression amplifies, whereas ablation of its TRAF3-binding domain replaces BAFF:BAFF-R-mediated survival signals in B cells. Proc Natl Acad Sci U S A (2008) 1.47
Latent membrane protein 1 of Epstein-Barr virus coordinately regulates proliferation with control of apoptosis. Oncogene (2005) 1.47
Single copy shRNA configuration for ubiquitous gene knockdown in mice. Nucleic Acids Res (2005) 1.44
Identification and functional analysis of tumor-infiltrating plasmacytoid dendritic cells in head and neck cancer. Cancer Res (2003) 1.44
On the abundance of EpCAM on cancer stem cells. Nat Rev Cancer (2009) 1.41
Control of Epstein-Barr virus reactivation by activated CD40 and viral latent membrane protein 1. Proc Natl Acad Sci U S A (2001) 1.40
Notch1 and Notch2 receptors influence progressive hair graying in a dose-dependent manner. Dev Dyn (2007) 1.40
Constitutive CD40 signaling in B cells selectively activates the noncanonical NF-kappaB pathway and promotes lymphomagenesis. J Exp Med (2008) 1.34
CD44s and CD44v6 expression in head and neck epithelia. PLoS One (2008) 1.33
EpCAM is involved in maintenance of the murine embryonic stem cell phenotype. Stem Cells (2009) 1.31
BAFF activates Akt and Erk through BAFF-R in an IKK1-dependent manner in primary mouse B cells. Proc Natl Acad Sci U S A (2008) 1.29
Super-SILAC allows classification of diffuse large B-cell lymphoma subtypes by their protein expression profiles. Mol Cell Proteomics (2012) 1.29
Conditional brain-specific knockdown of MAPK using Cre/loxP regulated RNA interference. Nucleic Acids Res (2007) 1.28
Phenotypic annotation of the mouse X chromosome. Genome Res (2010) 1.26
Forebrain-specific knockout of B-raf kinase leads to deficits in hippocampal long-term potentiation, learning, and memory. J Neurosci Res (2006) 1.25
Modeling disease mutations by gene targeting in one-cell mouse embryos. Proc Natl Acad Sci U S A (2012) 1.25
Skin lesion development in a mouse model of incontinentia pigmenti is triggered by NEMO deficiency in epidermal keratinocytes and requires TNF signaling. Hum Mol Genet (2006) 1.22
NF-κB essential modulator (NEMO) interaction with linear and lys-63 ubiquitin chains contributes to NF-κB activation. J Biol Chem (2011) 1.22
Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation. Immunity (2013) 1.21
Constitutive IKK2 activation in intestinal epithelial cells induces intestinal tumors in mice. J Clin Invest (2011) 1.20
Development of immunoglobulin lambda-chain-positive B cells, but not editing of immunoglobulin kappa-chain, depends on NF-kappaB signals. Nat Immunol (2009) 1.19
The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma. J Exp Med (2010) 1.18
Conditional ablation of Notch signaling in pancreatic development. Development (2008) 1.16
Initial activation of EpCAM cleavage via cell-to-cell contact. BMC Cancer (2009) 1.14
NIK signaling in dendritic cells but not in T cells is required for the development of effector T cells and cell-mediated immune responses. J Exp Med (2011) 1.13
Highly efficient targeted mutagenesis in mice using TALENs. Genetics (2013) 1.12
Loss of Roquin induces early death and immune deregulation but not autoimmunity. J Exp Med (2011) 1.11
EpCAM and its potential role in tumor-initiating cells. Cell Adh Migr (2012) 1.07
Tumor-specific glycosylation of the carcinoma-associated epithelial cell adhesion molecule EpCAM in head and neck carcinomas. Cancer Lett (2003) 1.06
LMP1 signaling can replace CD40 signaling in B cells in vivo and has unique features of inducing class-switch recombination to IgG1. Blood (2007) 1.05
Post-induction, stimulus-specific regulation of tumor necrosis factor mRNA expression. J Biol Chem (2007) 1.05
Differential mRNA distribution of components of the ERK/MAPK signalling cascade in the adult mouse brain. J Comp Neurol (2007) 1.04
Signatures of murine B-cell development implicate Yy1 as a regulator of the germinal center-specific program. Proc Natl Acad Sci U S A (2011) 1.02
The tumour-associated antigen EpCAM upregulates the fatty acid binding protein E-FABP. Cancer Lett (2004) 1.01
CK8 correlates with malignancy in leukoplakia and carcinomas of the head and neck. Biochem Biophys Res Commun (2006) 1.01
Glycosylation is crucial for stability of tumour and cancer stem cell antigen EpCAM. Front Biosci (2008) 0.99
Generation of targeted mouse mutants by embryo microinjection of TALEN mRNA. Nat Protoc (2013) 0.99
Heterogeneous nuclear ribonucleoprotein H blocks MST2-mediated apoptosis in cancer cells by regulating A-Raf transcription. Cancer Res (2010) 0.98
Generating conditional knockout mice. Methods Mol Biol (2011) 0.97
Analysis of plasmacytoid and myeloid dendritic cells in nasal epithelium. Clin Vaccine Immunol (2006) 0.97
Identification of epidermal Pdx1 expression discloses different roles of Notch1 and Notch2 in murine Kras(G12D)-induced skin carcinogenesis in vivo. PLoS One (2010) 0.97
Allogenic antibody-mediated identification of head and neck cancer antigens. Biochem Biophys Res Commun (2004) 0.96
CXC chemokine receptor 4 is essential for maintenance of renal cell carcinoma-initiating cells and predicts metastasis. Stem Cells (2013) 0.96
Epithelial NF-kappaB maintains host gut microflora homeostasis. Nat Immunol (2007) 0.96
Inhibition of the invasion capacity of carcinoma cells by WX-UK1, a novel synthetic inhibitor of the urokinase-type plasminogen activator system. Int J Cancer (2004) 0.96
N-linked glycosylation enrichment for in-depth cell surface proteomics of diffuse large B-cell lymphoma subtypes. Mol Cell Proteomics (2013) 0.95