Published in Int J Cancer on August 30, 2011
A Melanoma Brain Metastasis with a Donor-Patient Hybrid Genome following Bone Marrow Transplantation: First Evidence for Fusion in Human Cancer. PLoS One (2013) 1.08
Human pontine glioma cells can induce murine tumors. Acta Neuropathol (2014) 0.92
Fusion of CCL21 non-migratory active breast epithelial and breast cancer cells give rise to CCL21 migratory active tumor hybrid cell lines. PLoS One (2013) 0.87
Horizontal transmission of malignancy: in-vivo fusion of human lymphomas with hamster stroma produces tumors retaining human genes and lymphoid pathology. PLoS One (2013) 0.87
Fusion of bone marrow-derived cells with cancer cells: metastasis as a secondary disease in cancer. Chin J Cancer (2014) 0.85
Reversal of chemosensitivity and induction of cell malignancy of a non-malignant prostate cancer cell line upon extracellular vesicle exposure. Mol Cancer (2013) 0.84
Experimental research of host macrophage canceration induced by glioma stem progenitor cells. Mol Med Rep (2014) 0.82
In-vivo fusion of human cancer and hamster stromal cells permanently transduces and transcribes human DNA. PLoS One (2014) 0.79
Just like the rest of evolution in Mother Nature, the evolution of cancers may be driven by natural selection, and not by haphazard mutations. Oncoscience (2014) 0.79
The Dark Side of Cell Fusion. Int J Mol Sci (2016) 0.78
The role of pleomorphic adenoma gene-like 2 in gastrointestinal cancer development, progression, and prognosis. Int J Clin Exp Pathol (2014) 0.77
Transfer of malignant trait to immortalized human cells following exposure to human cancer serum. J Exp Clin Cancer Res (2014) 0.76
Extracellular Vesicle-Mediated Reversal of Paclitaxel Resistance in Prostate Cancer. Crit Rev Oncog (2015) 0.75
Microenvironmental regulation of metastasis. Nat Rev Cancer (2008) 15.76
Friends or foes - bipolar effects of the tumour stroma in cancer. Nat Rev Cancer (2004) 9.68
Concurrent and independent genetic alterations in the stromal and epithelial cells of mammary carcinoma: implications for tumorigenesis. Cancer Res (2000) 3.06
Stromal cells can contribute oncogenic signals. Semin Cancer Biol (2001) 2.80
PLAGL2 regulates Wnt signaling to impede differentiation in neural stem cells and gliomas. Cancer Cell (2010) 2.68
Malignant cells facilitate lung metastasis by bringing their own soil. Proc Natl Acad Sci U S A (2010) 2.62
Identification and localization of the cytokine SDF1 and its receptor, CXC chemokine receptor 4, to regions of necrosis and angiogenesis in human glioblastoma. Clin Cancer Res (2000) 2.52
Unveiling the mechanisms of cell-cell fusion. Science (2005) 2.52
Fusion of tumour cells with bone marrow-derived cells: a unifying explanation for metastasis. Nat Rev Cancer (2008) 2.17
Cell-to-cell fusion as a link between viruses and cancer. Nat Rev Cancer (2007) 1.93
Biological implications of cell fusion. Nat Rev Mol Cell Biol (2005) 1.87
Fusion between Intestinal epithelial cells and macrophages in a cancer context results in nuclear reprogramming. Cancer Res (2011) 1.73
Genetic disparity between primary tumours, disseminated tumour cells, and manifest metastasis. Int J Cancer (2010) 1.60
A functional heteromeric MIF receptor formed by CD74 and CXCR4. FEBS Lett (2009) 1.54
A virus causes cancer by inducing massive chromosomal instability through cell fusion. Curr Biol (2007) 1.51
CD74: a new candidate target for the immunotherapy of B-cell neoplasms. Clin Cancer Res (2007) 1.51
Efficient acquisition of dual metastasis organotropism to bone and lung through stable spontaneous fusion between MDA-MB-231 variants. Proc Natl Acad Sci U S A (2009) 1.45
The analysis of malignancy by cell fusion: the position in 1988. Cancer Res (1988) 1.38
CXCR4 expression mediates glioma cell invasiveness. Oncogene (2006) 1.37
Stroma: tumor agonist or antagonist. Cell Cycle (2005) 1.28
Donor Y chromosome in renal carcinoma cells of a female BMT recipient: visualization of putative BMT-tumor hybrids by FISH. Bone Marrow Transplant (2005) 1.27
Cell-free nucleic acids circulating in the plasma of colorectal cancer patients induce the oncogenic transformation of susceptible cultured cells. Cancer Res (2010) 1.24
Spontaneous fusion with, and transformation of mouse stroma by, malignant human breast cancer epithelium. Cancer Res (2006) 1.21
Macrophage fusion: are somatic and cancer cells possible partners? Trends Cell Biol (2005) 1.20
In vivo hybridisation of human tumour and normal hamster cells. Nature (1974) 1.20
Inflammation and proliferation act together to mediate intestinal cell fusion. PLoS One (2009) 1.18
Malignant potential of murine stromal cells after transplantation of human tumors into nude mice. Science (1981) 1.16
A spontaneous murine melanoma lung metastasis comprised of host x tumor hybrids. Cancer Res (2000) 1.11
Recurrence cancer stem cells--made by cell fusion? Med Hypotheses (2009) 1.05
Induction of sarcomas in athymic mice. Proc Natl Acad Sci U S A (1982) 1.05
In vivo human-hamster somatic cell fusion indicated by glucose 6-phosphate dehydrogenase and lactate dehydrogenase profiles. Cancer Res (1971) 0.99
Identification of alterations in DNA copy number in host stromal cells during tumor progression. Proc Natl Acad Sci U S A (2006) 0.99
Somatic cell fusion as a source of genetic rearrangement leading to metastatic variants. Cancer Metastasis Rev (1984) 0.97
Horizontal transfer of DNA by the uptake of apoptotic bodies. Vox Sang (2002) 0.94
In vivo horizontal oncogenesis by a human tumor in nude mice. Proc Natl Acad Sci U S A (1982) 0.94
Cell fusions in mammals. Histochem Cell Biol (2008) 0.93
Nonmetastatic tumor cells acquire metastatic properties following somatic hybridization with normal cells. Cancer Metastasis Rev (1984) 0.93
Molecular characterization of CXCR-4: a potential brain tumor-associated gene. J Surg Oncol (1998) 0.92
Production of a more aggressive tumor cell variant by spontaneous fusion of two mouse tumor subpopulations. Cancer Res (1989) 0.90
On the 'human' nature of highly malignant heterotransplantable tumors of human origin. Eur J Cancer (1968) 0.87
[On the progression of malignity: a hypothesis]. Klin Wochenschr (1968) 0.86
Horizontal transmission of malignant conditions rediscovered. N Engl J Med (1981) 0.85
Somatic cell hybridization in vivo and in vitro in relation to the metastatic phenotype. Biochim Biophys Acta (1985) 0.82
Primary transfection as a mechanism for transformation of host cells by human tumor cells implanted in nude mice. Cancer Res (1987) 0.80
Antigenic characterization of a heterotransplanted human tumour, GW-127. Experientia (1968) 0.79
Stathmokinetic effect of colcemid on a presumptive human-hamster hybrid tumor, GW-478. Exp Mol Pathol (1971) 0.79
Karyology of a human colonic carcinoma (GW-39) serially xenografted in hamsters and in nude mice. Cancer Lett (1977) 0.78
Oncogenesis by interspecific interaction of malignant murine and non-malignant hamster cells in vitro. Int J Cancer (1975) 0.77
Prediction of central nervous system embryonal tumour outcome based on gene expression. Nature (2002) 15.36
From silencing to gene expression: real-time analysis in single cells. Cell (2004) 7.73
SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin. Nature (2008) 6.02
Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice. Cancer Cell (2008) 5.11
Transforming fusions of FGFR and TACC genes in human glioblastoma. Science (2012) 5.09
Glioma grading: sensitivity, specificity, and predictive values of perfusion MR imaging and proton MR spectroscopic imaging compared with conventional MR imaging. AJNR Am J Neuroradiol (2003) 4.44
Positional stability of single double-strand breaks in mammalian cells. Nat Cell Biol (2007) 4.35
Comparison of cerebral blood volume and vascular permeability from dynamic susceptibility contrast-enhanced perfusion MR imaging with glioma grade. AJNR Am J Neuroradiol (2004) 3.56
Cytogenetic evidence that circulating epithelial cells in patients with carcinoma are malignant. Clin Cancer Res (2002) 3.54
Hypoxia-inducible factor-1-dependent repression of E-cadherin in von Hippel-Lindau tumor suppressor-null renal cell carcinoma mediated by TCF3, ZFHX1A, and ZFHX1B. Cancer Res (2006) 3.05
Clonal selection drives genetic divergence of metastatic medulloblastoma. Nature (2012) 2.96
Actin-dependent intranuclear repositioning of an active gene locus in vivo. J Cell Biol (2007) 2.93
Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification. J Exp Med (2002) 2.86
Gliomas: predicting time to progression or survival with cerebral blood volume measurements at dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging. Radiology (2008) 2.83
Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis. Lancet Oncol (2013) 2.82
Survival improvement in patients with medullary thyroid carcinoma who undergo pretargeted anti-carcinoembryonic-antigen radioimmunotherapy: a collaborative study with the French Endocrine Tumor Group. J Clin Oncol (2006) 2.79
ATM prevents the persistence and propagation of chromosome breaks in lymphocytes. Cell (2007) 2.78
AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations. Mol Cell (2009) 2.75
Antiangiogenic therapy using bevacizumab in recurrent high-grade glioma: impact on local control and patient survival. J Neurosurg (2009) 2.66
Silence of chromosomal amplifications in colon cancer. Cancer Res (2002) 2.58
Accumulated chromosomal instability in murine bone marrow mesenchymal stem cells leads to malignant transformation. Stem Cells (2005) 2.52
Intracranial mass lesions: dynamic contrast-enhanced susceptibility-weighted echo-planar perfusion MR imaging. Radiology (2002) 2.41
A novel method of 18F radiolabeling for PET. J Nucl Med (2009) 2.35
Low-grade gliomas: dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging--prediction of patient clinical response. Radiology (2006) 2.22
Low dose oral desmopressin for nocturnal polyuria in patients with benign prostatic hyperplasia: a double-blind, placebo controlled, randomized study. J Urol (2010) 2.17
Angiogenesis in gliomas: biology and molecular pathophysiology. Brain Pathol (2005) 2.16
Cell cycle arrest and repression of cyclin D1 transcription by INI1/hSNF5. Mol Cell Biol (2002) 2.15
Chromosomal instability determines taxane response. Proc Natl Acad Sci U S A (2009) 2.12
Of mice and MEN1: Insulinomas in a conditional mouse knockout. Mol Cell Biol (2003) 2.12
Effectiveness of gene expression profiling for response prediction of rectal adenocarcinomas to preoperative chemoradiotherapy. J Clin Oncol (2005) 2.07
UOK 262 cell line, fumarate hydratase deficient (FH-/FH-) hereditary leiomyomatosis renal cell carcinoma: in vitro and in vivo model of an aberrant energy metabolic pathway in human cancer. Cancer Genet Cytogenet (2010) 2.06
The XIST noncoding RNA functions independently of BRCA1 in X inactivation. Cell (2007) 2.00
CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia. Nature (2009) 1.94
Integrative genomics reveals mechanisms of copy number alterations responsible for transcriptional deregulation in colorectal cancer. Genes Chromosomes Cancer (2009) 1.91
Dynamic contrast-enhanced perfusion MR imaging measurements of endothelial permeability: differentiation between atypical and typical meningiomas. AJNR Am J Neuroradiol (2003) 1.83
Insertion of c-Myc into Igh induces B-cell and plasma-cell neoplasms in mice. Cancer Res (2005) 1.83
Dynamic, contrast-enhanced perfusion MRI in mouse gliomas: correlation with histopathology. Magn Reson Med (2003) 1.78
Trogocytosis of multiple B-cell surface markers by CD22 targeting with epratuzumab. Blood (2013) 1.78
Solid renal tumor severity in von Hippel Lindau disease is related to germline deletion length and location. Hum Mutat (2004) 1.78
Targeting, toxicity, and efficacy of 2-step, pretargeted radioimmunotherapy using a chimeric bispecific antibody and 131I-labeled bivalent hapten in a phase I optimization clinical trial. J Nucl Med (2006) 1.77
Improved 18F labeling of peptides with a fluoride-aluminum-chelate complex. Bioconjug Chem (2010) 1.76
Chimeric IgH-TCRalpha/delta translocations in T lymphocytes mediated by RAG. Cell Cycle (2009) 1.75
Chromosome transfer induced aneuploidy results in complex dysregulation of the cellular transcriptome in immortalized and cancer cells. Cancer Res (2004) 1.74
Increased serum levels of complement C3a anaphylatoxin indicate the presence of colorectal tumors. Gastroenterology (2006) 1.72
The interactive online SKY/M-FISH & CGH database and the Entrez cancer chromosomes search database: linkage of chromosomal aberrations with the genome sequence. Genes Chromosomes Cancer (2005) 1.70
Inflammation-mediated genetic and epigenetic alterations drive cancer development in the neighboring epithelium upon stromal abrogation of TGF-β signaling. PLoS Genet (2013) 1.69
Signal amplification in molecular imaging by pretargeting a multivalent, bispecific antibody. Nat Med (2005) 1.69
Retracted A genomic approach to colon cancer risk stratification yields biologic insights into therapeutic opportunities. Proc Natl Acad Sci U S A (2008) 1.69
Dual-targeting immunotherapy of lymphoma: potent cytotoxicity of anti-CD20/CD74 bispecific antibodies in mantle cell and other lymphomas. Blood (2012) 1.63
The rectal cancer microRNAome--microRNA expression in rectal cancer and matched normal mucosa. Clin Cancer Res (2012) 1.61
High-grade glioma before and after treatment with radiation and Avastin: initial observations. Neuro Oncol (2008) 1.61
BRAF alterations in primary glial and glioneuronal neoplasms of the central nervous system with identification of 2 novel KIAA1549:BRAF fusion variants. J Neuropathol Exp Neurol (2012) 1.60
IFN-gamma determines distinct clinical outcomes in autoimmune encephalomyelitis. J Immunol (2005) 1.56
The Septin 9 (MSF) gene is amplified and overexpressed in mouse mammary gland adenocarcinomas and human breast cancer cell lines. Cancer Res (2003) 1.56
53BP1 cooperates with p53 and functions as a haploinsufficient tumor suppressor in mice. Mol Cell Biol (2005) 1.56
Assessing global invasion of newly diagnosed glial tumors with whole-brain proton MR spectroscopy. AJNR Am J Neuroradiol (2005) 1.56
Perfusion magnetic resonance imaging predicts patient outcome as an adjunct to histopathology: a second reference standard in the surgical and nonsurgical treatment of low-grade gliomas. Neurosurgery (2006) 1.54
Gene expression profiling reveals a massive, aneuploidy-dependent transcriptional deregulation and distinct differences between lymph node-negative and lymph node-positive colon carcinomas. Cancer Res (2007) 1.53
A clinical trial of bevacizumab, temozolomide, and radiation for newly diagnosed glioblastoma. J Neurosurg (2011) 1.52
Spectral karyotyping analysis of human and mouse chromosomes. Nat Protoc (2006) 1.52
A virus causes cancer by inducing massive chromosomal instability through cell fusion. Curr Biol (2007) 1.51
The combination of ionizing radiation and peripheral vaccination produces long-term survival of mice bearing established invasive GL261 gliomas. Clin Cancer Res (2006) 1.51
CD74: a new candidate target for the immunotherapy of B-cell neoplasms. Clin Cancer Res (2007) 1.51
Combined breast ductal lavage and ductal endoscopy for the evaluation of the high-risk breast: a feasibility study. J Surg Oncol (2006) 1.51
Stably tethered multifunctional structures of defined composition made by the dock and lock method for use in cancer targeting. Proc Natl Acad Sci U S A (2006) 1.50
Knock down of HIF-1alpha in glioma cells reduces migration in vitro and invasion in vivo and impairs their ability to form tumor spheres. Mol Cancer (2010) 1.50
Mutated KRAS results in overexpression of DUSP4, a MAP-kinase phosphatase, and SMYD3, a histone methyltransferase, in rectal carcinomas. Genes Chromosomes Cancer (2010) 1.50
Improving the delivery of radionuclides for imaging and therapy of cancer using pretargeting methods. Clin Cancer Res (2005) 1.49
Genetic ablation of Cyclin D1 abrogates genesis of rhabdoid tumors resulting from Ini1 loss. Proc Natl Acad Sci U S A (2005) 1.48
Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability. Genome Res (2013) 1.47
A sequence-based survey of the complex structural organization of tumor genomes. Genome Biol (2008) 1.45
Chromosomal breakpoints in primary colon cancer cluster at sites of structural variants in the genome. Cancer Res (2008) 1.44
LGR5 positivity defines stem-like cells in colorectal cancer. Carcinogenesis (2013) 1.41
Mechanisms of glioma-associated neovascularization. Am J Pathol (2012) 1.39
Diffusion-tensor MR imaging of intracranial neoplasia and associated peritumoral edema: introduction of the tumor infiltration index. Radiology (2004) 1.39
AID-deficient Bcl-xL transgenic mice develop delayed atypical plasma cell tumors with unusual Ig/Myc chromosomal rearrangements. J Exp Med (2007) 1.37
Isolation and solubilization of proteins after TRIzol extraction of RNA and DNA from patient material following prolonged storage. Biotechniques (2007) 1.36
Proton MR spectroscopy of tumefactive demyelinating lesions. AJNR Am J Neuroradiol (2002) 1.36
Induction of medulloblastomas in mice by sonic hedgehog, independent of Gli1. Cancer Res (2002) 1.36
Centrosome abnormalities, recurring deletions of chromosome 4, and genomic amplification of HER2/neu define mouse mammary gland adenocarcinomas induced by mutant HER2/neu. Oncogene (2002) 1.36
Multifunctional antibodies by the Dock-and-Lock method for improved cancer imaging and therapy by pretargeting. J Nucl Med (2007) 1.35
Decreased microRNA-214 levels in breast cancer cells coincides with increased cell proliferation, invasion and accumulation of the Polycomb Ezh2 methyltransferase. Carcinogenesis (2011) 1.35
The gene expression signature of genomic instability in breast cancer is an independent predictor of clinical outcome. Int J Cancer (2009) 1.34
Resistance of glioblastoma-initiating cells to radiation mediated by the tumor microenvironment can be abolished by inhibiting transforming growth factor-β. Cancer Res (2012) 1.34
Detection of genomic amplification of the human telomerase gene (TERC) in cytologic specimens as a genetic test for the diagnosis of cervical dysplasia. Am J Pathol (2003) 1.33
Cytokine-independent growth and clonal expansion of a primary human CD8+ T-cell clone following retroviral transduction with the IL-15 gene. Blood (2007) 1.32
Genomic amplification of the human telomerase gene (TERC) in pap smears predicts the development of cervical cancer. Am J Pathol (2005) 1.32
Integration of metabolomics and transcriptomics revealed a fatty acid network exerting growth inhibitory effects in human pancreatic cancer. Clin Cancer Res (2013) 1.31
Aneuploidy-dependent massive deregulation of the cellular transcriptome and apparent divergence of the Wnt/beta-catenin signaling pathway in human rectal carcinomas. Cancer Res (2006) 1.31
Pretargeted molecular imaging and radioimmunotherapy. Theranostics (2012) 1.31
Properties and structure-function relationships of veltuzumab (hA20), a humanized anti-CD20 monoclonal antibody. Blood (2008) 1.30
DPEP1 inhibits tumor cell invasiveness, enhances chemosensitivity and predicts clinical outcome in pancreatic ductal adenocarcinoma. PLoS One (2012) 1.30
Tissue-specific reduction in splicing efficiency of IKBKAP due to the major mutation associated with familial dysautonomia. Am J Hum Genet (2003) 1.26
Stage-specific alterations of the genome, transcriptome, and proteome during colorectal carcinogenesis. Genes Chromosomes Cancer (2007) 1.26
Receptor protein tyrosine phosphatase alpha is essential for hippocampal neuronal migration and long-term potentiation. EMBO J (2003) 1.25
CD74 is expressed by multiple myeloma and is a promising target for therapy. Clin Cancer Res (2004) 1.25
Involvement of Crm1 in hepatitis B virus X protein-induced aberrant centriole replication and abnormal mitotic spindles. Mol Cell Biol (2003) 1.24
The UOK 257 cell line: a novel model for studies of the human Birt-Hogg-Dubé gene pathway. Cancer Genet Cytogenet (2008) 1.24