Label-free shotgun proteomics and metabolite analysis reveal a significant metabolic shift during citrus fruit development.

PubWeight™: 0.90‹?›

🔗 View Article (PMC 3223037)

Published in J Exp Bot on August 12, 2011

Authors

Ehud Katz1, Kyung Hwan Boo, Ho Youn Kim, Richard A Eigenheer, Brett S Phinney, Vladimir Shulaev, Florence Negre-Zakharov, Avi Sadka, Eduardo Blumwald

Author Affiliations

1: Department of Plant Sciences, University of California, Davis, CA 95616, USA.

Articles cited by this

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem (1976) 903.81

Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods (2001) 414.27

Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search. Anal Chem (2002) 35.30

A statistical model for identifying proteins by tandem mass spectrometry. Anal Chem (2003) 29.58

Correlation between protein and mRNA abundance in yeast. Mol Cell Biol (1999) 16.95

MAPMAN: a user-driven tool to display genomics data sets onto diagrams of metabolic pathways and other biological processes. Plant J (2004) 15.51

Quantitative mass spectrometry in proteomics: a critical review. Anal Bioanal Chem (2007) 6.80

Comparative evaluation of mass spectrometry platforms used in large-scale proteomics investigations. Nat Methods (2005) 6.73

Assigning significance to peptides identified by tandem mass spectrometry using decoy databases. J Proteome Res (2007) 5.57

Technical advance: simultaneous analysis of metabolites in potato tuber by gas chromatography-mass spectrometry. Plant J (2000) 4.64

Extension of the visualization tool MapMan to allow statistical analysis of arrays, display of corresponding genes, and comparison with known responses. Plant Physiol (2005) 4.34

Sucrose metabolism: regulatory mechanisms and pivotal roles in sugar sensing and plant development. Curr Opin Plant Biol (2004) 4.14

A Robot-based platform to measure multiple enzyme activities in Arabidopsis using a set of cycling assays: comparison of changes of enzyme activities and transcript levels during diurnal cycles and in prolonged darkness. Plant Cell (2004) 3.24

Significance analysis of spectral count data in label-free shotgun proteomics. Mol Cell Proteomics (2008) 3.12

Putative regulatory sites unraveled by network-embedded thermodynamic analysis of metabolome data. Mol Syst Biol (2006) 3.04

Integrated analysis of metabolite and transcript levels reveals the metabolic shifts that underlie tomato fruit development and highlight regulatory aspects of metabolic network behavior. Plant Physiol (2006) 2.55

Integration of metabolite with transcript and enzyme activity profiling during diurnal cycles in Arabidopsis rosettes. Genome Biol (2006) 2.25

Quantitation in mass-spectrometry-based proteomics. Annu Rev Plant Biol (2010) 2.14

Transcriptomic and metabolite analyses of Cabernet Sauvignon grape berry development. BMC Genomics (2007) 2.13

Not just a circle: flux modes in the plant TCA cycle. Trends Plant Sci (2010) 1.96

Mitochondrial succinic-semialdehyde dehydrogenase of the gamma-aminobutyrate shunt is required to restrict levels of reactive oxygen intermediates in plants. Proc Natl Acad Sci U S A (2003) 1.74

Comparative LC-MS: a landscape of peaks and valleys. Proteomics (2008) 1.73

Sucrose-metabolizing enzymes in transport tissues and adjacent sink structures in developing citrus fruit. Plant Physiol (1989) 1.65

Characterizing the grape transcriptome. Analysis of expressed sequence tags from multiple Vitis species and development of a compendium of gene expression during berry development. Plant Physiol (2005) 1.65

Regulation of malate metabolism in grape berry and other developing fruits. Phytochemistry (2009) 1.56

Reconfiguration of the achene and receptacle metabolic networks during strawberry fruit development. Plant Physiol (2008) 1.53

Gene and metabolite regulatory network analysis of early developing fruit tissues highlights new candidate genes for the control of tomato fruit composition and development. Plant Physiol (2009) 1.50

Posttranslational elevation of cell wall invertase activity by silencing its inhibitor in tomato delays leaf senescence and increases seed weight and fruit hexose level. Plant Cell (2009) 1.42

Sucrose synthase and invertase in isolated vascular bundles. Plant Physiol (1991) 1.31

NAD malic enzyme and the control of carbohydrate metabolism in potato tubers. Plant Physiol (2001) 1.27

Global analysis of gene expression during development and ripening of citrus fruit flesh. A proposed mechanism for citric Acid utilization. Plant Mol Biol (2006) 1.25

Postphloem, nonvascular transfer in citrus: kinetics, metabolism, and sugar gradients. Plant Physiol (1990) 1.22

Citrus genomics. Int J Plant Genomics (2008) 1.19

Purification, molecular cloning, and sequence analysis of sucrose-6F-phosphate phosphohydrolase from plants. Proc Natl Acad Sci U S A (2000) 1.15

Integration of metabolomic and proteomic phenotypes: analysis of data covariance dissects starch and RFO metabolism from low and high temperature compensation response in Arabidopsis thaliana. Mol Cell Proteomics (2008) 1.13

Metabolic characterization of loci affecting sensory attributes in tomato allows an assessment of the influence of the levels of primary metabolites and volatile organic contents. J Exp Bot (2009) 1.11

Analysis of sucrose synthase genes in citrus suggests different roles and phylogenetic relationships. J Exp Bot (2002) 1.07

Molecular and physiological evidence suggests the existence of a system II-like pathway of ethylene production in non-climacteric Citrus fruit. Planta (2004) 1.06

NADP(+)-isocitrate dehydrogenase gene expression and isozyme activity during citrus fruit development. Plant Sci (2000) 1.05

The citrus fruit proteome: insights into citrus fruit metabolism. Planta (2007) 1.02

Transcriptome profiling of ripening nectarine (Prunus persica L. Batsch) fruit treated with 1-MCP. J Exp Bot (2008) 0.98

Elevated sucrose-phosphate synthase activity in transgenic tobacco sustains photosynthesis in older leaves and alters development. J Exp Bot (2003) 0.94

Characterisation of the ATP-dependent phosphofructokinase gene family from Arabidopsis thaliana. FEBS Lett (2007) 0.92

Vacuolar citrate/H+ symporter of citrus juice cells. Planta (2006) 0.91

A label-free differential quantitative mass spectrometry method for the characterization and identification of protein changes during citrus fruit development. Proteome Sci (2010) 0.91

Molecular characterization of the mitochondrial citrate synthase gene of an acidless pummelo (Citrus maxima). Plant Mol Biol (1996) 0.88

Articles by these authors

ROS signaling: the new wave? Trends Plant Sci (2011) 4.45

Global analysis of protein palmitoylation in yeast. Cell (2006) 4.43

Cytosolic ascorbate peroxidase 1 is a central component of the reactive oxygen gene network of Arabidopsis. Plant Cell (2004) 3.83

When defense pathways collide. The response of Arabidopsis to a combination of drought and heat stress. Plant Physiol (2004) 3.80

Identification and functional analysis of in vivo phosphorylation sites of the Arabidopsis BRASSINOSTEROID-INSENSITIVE1 receptor kinase. Plant Cell (2005) 3.48

Transcriptomic footprints disclose specificity of reactive oxygen species signaling in Arabidopsis. Plant Physiol (2006) 3.47

The plant NADPH oxidase RBOHD mediates rapid systemic signaling in response to diverse stimuli. Sci Signal (2009) 2.99

Plant neurobiology: no brain, no gain? Trends Plant Sci (2007) 2.83

Delayed leaf senescence induces extreme drought tolerance in a flowering plant. Proc Natl Acad Sci U S A (2007) 2.65

Reactive oxygen signaling and abiotic stress. Physiol Plant (2008) 2.56

Genetic engineering for modern agriculture: challenges and perspectives. Annu Rev Plant Biol (2010) 2.48

The role of neutral lipid nanospheres in Plasmodium falciparum haem crystallization. Biochem J (2007) 2.27

Hormone balance and abiotic stress tolerance in crop plants. Curr Opin Plant Biol (2011) 2.24

Developing salt-tolerant crop plants: challenges and opportunities. Trends Plant Sci (2005) 2.20

Respiratory burst oxidases: the engines of ROS signaling. Curr Opin Plant Biol (2011) 2.15

Jasmonate-inducible plant enzymes degrade essential amino acids in the herbivore midgut. Proc Natl Acad Sci U S A (2005) 1.93

Abiotic and biotic stress combinations. New Phytol (2014) 1.89

Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis. J Proteome Res (2003) 1.81

Enhanced tolerance to environmental stress in transgenic plants expressing the transcriptional coactivator multiprotein bridging factor 1c. Plant Physiol (2005) 1.76

Vacuolar cation/H+ exchange, ion homeostasis, and leaf development are altered in a T-DNA insertional mutant of AtNHX1, the Arabidopsis vacuolar Na+/H+ antiporter. Plant J (2003) 1.75

The Arabidopsis Na+/H+ antiporters NHX1 and NHX2 control vacuolar pH and K+ homeostasis to regulate growth, flower development, and reproduction. Plant Cell (2011) 1.66

The Arabidopsis intracellular Na+/H+ antiporters NHX5 and NHX6 are endosome associated and necessary for plant growth and development. Plant Cell (2011) 1.63

Manipulation of small Rho GTPases is a pathogen-induced process detected by NOD1. Nature (2013) 1.63

Analysis of the pumpkin phloem proteome provides insights into angiosperm sieve tube function. Mol Cell Proteomics (2008) 1.61

Engineering salt tolerance in plants. Curr Opin Biotechnol (2002) 1.57

The Association of Biomolecular Resource Facilities Proteomics Research Group 2006 study: relative protein quantitation. Mol Cell Proteomics (2007) 1.53

Na+ transport in plants. FEBS Lett (2007) 1.48

Ascorbate peroxidase 1 plays a key role in the response of Arabidopsis thaliana to stress combination. J Biol Chem (2008) 1.47

Plasmodium falciparum-infected erythrocytes induce NF-kappaB regulated inflammatory pathways in human cerebral endothelium. Blood (2009) 1.46

Methylation of gibberellins by Arabidopsis GAMT1 and GAMT2. Plant Cell (2007) 1.43

Whole genome comparisons of Fragaria, Prunus and Malus reveal different modes of evolution between Rosaceous subfamilies. BMC Genomics (2012) 1.43

High-efficiency transformation of the diploid strawberry (Fragaria vesca) for functional genomics. Planta (2005) 1.42

Vacuolar Na+/H+ antiporter cation selectivity is regulated by calmodulin from within the vacuole in a Ca2+- and pH-dependent manner. Proc Natl Acad Sci U S A (2005) 1.40

The transcriptional co-activator MBF1c is a key regulator of thermotolerance in Arabidopsis thaliana. J Biol Chem (2008) 1.39

PPARγ-mediated increase in glucose availability sustains chronic Brucella abortus infection in alternatively activated macrophages. Cell Host Microbe (2013) 1.38

Distinct roles of jasmonates and aldehydes in plant-defense responses. PLoS One (2008) 1.36

Cytokinin-dependent photorespiration and the protection of photosynthesis during water deficit. Plant Physiol (2009) 1.33

Expression of an Arabidopsis vacuolar H+-pyrophosphatase gene (AVP1) in cotton improves drought- and salt tolerance and increases fibre yield in the field conditions. Plant Biotechnol J (2011) 1.30

REVEILLE8 and PSEUDO-REPONSE REGULATOR5 form a negative feedback loop within the Arabidopsis circadian clock. PLoS Genet (2011) 1.29

Shotgun cross-linking analysis for studying quaternary and tertiary protein structures. J Proteome Res (2007) 1.27

Spatial mapping of lipids at cellular resolution in embryos of cotton. Plant Cell (2012) 1.24

3,5-Bis(4-chloro-benzyl-idene)-1-methyl-piperidin-4-one. Acta Crystallogr Sect E Struct Rep Online (2011) 1.24

Cytokinin-mediated source/sink modifications improve drought tolerance and increase grain yield in rice under water-stress. Plant Biotechnol J (2011) 1.22

Reanalysis of Tyrannosaurus rex Mass Spectra. J Proteome Res (2009) 1.21

Cellular ion homeostasis: emerging roles of intracellular NHX Na+/H+ antiporters in plant growth and development. J Exp Bot (2012) 1.18

A systems biology view of cancer. Biochim Biophys Acta (2009) 1.17

Metabolomics as a Hypothesis-Generating Functional Genomics Tool for the Annotation of Arabidopsis thaliana Genes of "Unknown Function". Front Plant Sci (2012) 1.17

Topological analysis of a plant vacuolar Na+/H+ antiporter reveals a luminal C terminus that regulates antiporter cation selectivity. Proc Natl Acad Sci U S A (2003) 1.15

PlantMetabolomics.org: a web portal for plant metabolomics experiments. Plant Physiol (2010) 1.15

NAF-1 and mitoNEET are central to human breast cancer proliferation by maintaining mitochondrial homeostasis and promoting tumor growth. Proc Natl Acad Sci U S A (2013) 1.14

Salt stress response in rice: genetics, molecular biology, and comparative genomics. Funct Integr Genomics (2006) 1.11

Bioinformatics tools for cancer metabolomics. Metabolomics (2011) 1.10

Extranuclear protection of chromosomal DNA from oxidative stress. Proc Natl Acad Sci U S A (2011) 1.09

Temporal-spatial interaction between reactive oxygen species and abscisic acid regulates rapid systemic acclimation in plants. Plant Cell (2013) 1.09

DNA array analyses of Arabidopsis thaliana lacking a vacuolar Na+/H+ antiporter: impact of AtNHX1 on gene expression. Plant J (2004) 1.07

Defective glycosylation of calsequestrin in heart failure. Cardiovasc Res (2004) 1.07

Interlinking showy traits: co-engineering of scent and colour biosynthesis in flowers. Plant Biotechnol J (2008) 1.07

Extracellular glycosylphosphatidylinositol-anchored mannoproteins and proteases of Cryptococcus neoformans. FEMS Yeast Res (2007) 1.03

Identification and characterization of Vnx1p, a novel type of vacuolar monovalent cation/H+ antiporter of Saccharomyces cerevisiae. J Biol Chem (2007) 1.03

Similar mechanisms might be triggered by alternative external stimuli that induce dormancy release in grape buds. Planta (2008) 1.03

Stomatal density and metabolic determinants mediate salt stress adaptation and water use efficiency in basil (Ocimum basilicum L.). J Plant Physiol (2012) 1.02

Sustained activation of Akt elicits mitochondrial dysfunction to block Plasmodium falciparum infection in the mosquito host. PLoS Pathog (2013) 1.01

Expression of an Arabidopsis vacuolar sodium/proton antiporter gene in cotton improves photosynthetic performance under salt conditions and increases fiber yield in the field. Plant Cell Physiol (2005) 1.01

Enhanced cytokinin synthesis in tobacco plants expressing PSARK::IPT prevents the degradation of photosynthetic protein complexes during drought. Plant Cell Physiol (2010) 1.00

Regulated expression of an isopentenyltransferase gene (IPT) in peanut significantly improves drought tolerance and increases yield under field conditions. Plant Cell Physiol (2011) 0.99

In vivo intracellular pH measurements in tobacco and Arabidopsis reveal an unexpected pH gradient in the endomembrane system. Plant Cell (2013) 0.99

The significance of protein maturation by plastidic type I signal peptidase 1 for thylakoid development in Arabidopsis chloroplasts. Plant Physiol (2010) 0.98

Soluble CD93 induces differentiation of monocytes and enhances TLR responses. J Immunol (2010) 0.98

Targeting metabolic pathways for genetic engineering abiotic stress-tolerance in crops. Biochim Biophys Acta (2011) 0.98

Proteomic analysis of human nail plate. J Proteome Res (2010) 0.97

Integrated analysis of ATM mediated gene and protein expression impacting cellular metabolism. J Proteome Res (2011) 0.97

Intracellular NHX-type cation/H+ antiporters in plants. Mol Plant (2013) 0.97

Implementing reverse genetics in Rosaceae: analysis of T-DNA flanking sequences of insertional mutant lines in the diploid strawberry, Fragaria vesca. Physiol Plant (2010) 0.97

Differentiating inbred mouse strains from each other and those with single gene mutations using hair proteomics. PLoS One (2012) 0.96

Parry-romberg syndrome with en coup de sabre. Ann Dermatol (2011) 0.96

Identification of in vivo phosphorylation sites of MLK3 by mass spectrometry and phosphopeptide mapping. Biochemistry (2002) 0.94

Determining the overall merit of protein identification data sets: rho-diagrams and rho-scores. J Proteome Res (2007) 0.94

Stress-induced cytokinin synthesis increases drought tolerance through the coordinated regulation of carbon and nitrogen assimilation in rice. Plant Physiol (2013) 0.94

Alternate bearing in citrus: changes in the expression of flowering control genes and in global gene expression in ON- versus OFF-crop trees. PLoS One (2012) 0.93

Water-deficit inducible expression of a cytokinin biosynthetic gene IPT improves drought tolerance in cotton. PLoS One (2013) 0.93

Identification and characterization of a NaCl-inducible vacuolar Na+/H+ antiporter in Beta vulgaris. Physiol Plant (2002) 0.93

Role of aromatic aldehyde synthase in wounding/herbivory response and flower scent production in different Arabidopsis ecotypes. Plant J (2011) 0.93

Functional assessment of the Medicago truncatula NIP/LATD protein demonstrates that it is a high-affinity nitrate transporter. Plant Physiol (2012) 0.93

Detection of differentially expressed basal cell proteins by mass spectrometry. Mol Cell Proteomics (2009) 0.92

Vacuolar citrate/H+ symporter of citrus juice cells. Planta (2006) 0.91

A label-free differential quantitative mass spectrometry method for the characterization and identification of protein changes during citrus fruit development. Proteome Sci (2010) 0.91

Effect of host cell lipid metabolism on alphavirus replication, virion morphogenesis, and infectivity. Proc Natl Acad Sci U S A (2008) 0.89

Interleukin-17 increases the expression of Toll-like receptor 3 via the STAT3 pathway in rheumatoid arthritis fibroblast-like synoviocytes. Immunology (2014) 0.89

Grape seed proanthocyanidin extract ameliorates monosodium iodoacetate-induced osteoarthritis. Exp Mol Med (2011) 0.88

Differential gene expression in normal and transformed human mammary epithelial cells in response to oxidative stress. Free Radic Biol Med (2011) 0.88