Published in J Am Chem Soc on September 14, 2011
The mechanisms of RNA SHAPE chemistry. J Am Chem Soc (2012) 1.52
Tuning a riboswitch response through structural extension of a pseudoknot. Proc Natl Acad Sci U S A (2013) 1.09
Structure and mechanism of purine-binding riboswitches. Q Rev Biophys (2012) 1.06
Escherichia coli ribosomal protein S1 unfolds structured mRNAs onto the ribosome for active translation initiation. PLoS Biol (2013) 0.91
Nucleotides adjacent to the ligand-binding pocket are linked to activity tuning in the purine riboswitch. J Mol Biol (2013) 0.89
Dynamics of RNA modification by a multi-site-specific tRNA methyltransferase. Nucleic Acids Res (2014) 0.85
Ligand- and pH-induced conformational changes of RNA domain helix 69 revealed by 2-aminopurine fluorescence. Angew Chem Int Ed Engl (2012) 0.83
An arginine-aspartate network in the active site of bacterial TruB is critical for catalyzing pseudouridine formation. Nucleic Acids Res (2013) 0.78
Switching on the fluorescence of 2-aminopurine by site-selective microhydration. Nat Chem (2014) 0.78
RNA secondary structure prediction using high-throughput SHAPE. J Vis Exp (2013) 0.77
Conformational Rearrangements of Individual Nucleotides during RNA-Ligand Binding Are Rate-Differentiated. J Am Chem Soc (2016) 0.75
Fluorescence-Based Strategies to Investigate the Structure and Dynamics of Aptamer-Ligand Complexes. Front Chem (2016) 0.75
A highly specific sodium aptamer probed by 2-aminopurine for robust Na+ sensing. Nucleic Acids Res (2016) 0.75
Structural basis for discriminative regulation of gene expression by adenine- and guanine-sensing mRNAs. Chem Biol (2004) 5.44
Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation. Nat Struct Mol Biol (2005) 2.50
Structural and functional insights into 5'-ppp RNA pattern recognition by the innate immune receptor RIG-I. Nat Struct Mol Biol (2010) 2.13
Ligand-induced folding of the adenosine deaminase A-riboswitch and implications on riboswitch translational control. Chembiochem (2007) 2.12
Nascent peptide in the ribosome exit tunnel affects functional properties of the A-site of the peptidyl transferase center. Mol Cell (2011) 1.96
Conformational capture of the SAM-II riboswitch. Nat Chem Biol (2011) 1.84
Ligand-induced folding of the thiM TPP riboswitch investigated by a structure-based fluorescence spectroscopic approach. Nucleic Acids Res (2007) 1.79
The role of 23S ribosomal RNA residue A2451 in peptide bond synthesis revealed by atomic mutagenesis. Chem Biol (2008) 1.79
The dynamic nature of RNA as key to understanding riboswitch mechanisms. Acc Chem Res (2011) 1.39
Folding of a transcriptionally acting preQ1 riboswitch. Proc Natl Acad Sci U S A (2010) 1.34
Chemical engineering of the peptidyl transferase center reveals an important role of the 2'-hydroxyl group of A2451. Nucleic Acids Res (2005) 1.29
Pseudoknot preorganization of the preQ1 class I riboswitch. J Am Chem Soc (2012) 1.20
Efficient ribosomal peptidyl transfer critically relies on the presence of the ribose 2'-OH at A2451 of 23S rRNA. J Am Chem Soc (2006) 1.20
Syntheses of RNAs with up to 100 nucleotides containing site-specific 2'-methylseleno labels for use in X-ray crystallography. J Am Chem Soc (2005) 1.18
An intact ribose moiety at A2602 of 23S rRNA is key to trigger peptidyl-tRNA hydrolysis during translation termination. Nucleic Acids Res (2007) 1.15
In vivo expression and purification of aptamer-tagged small RNA regulators. Nucleic Acids Res (2009) 1.15
Chemical synthesis of selenium-modified oligoribonucleotides and their enzymatic ligation leading to an U6 SnRNA stem-loop segment. J Am Chem Soc (2004) 1.15
The preparation of site-specifically modified riboswitch domains as an example for enzymatic ligation of chemically synthesized RNA fragments. Nat Protoc (2008) 1.15
Stem cells are differentially regulated during development, regeneration and homeostasis in flatworms. Dev Biol (2009) 1.11
Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme. Nucleic Acids Res (2007) 1.11
Bistable secondary structures of small RNAs and their structural probing by comparative imino proton NMR spectroscopy. J Mol Biol (2003) 1.11
Tuning a riboswitch response through structural extension of a pseudoknot. Proc Natl Acad Sci U S A (2013) 1.09
Folding and ligand recognition of the TPP riboswitch aptamer at single-molecule resolution. Proc Natl Acad Sci U S A (2013) 1.08
Ribose 2'-F labeling: a simple tool for the characterization of RNA secondary structure equilibria by 19F NMR spectroscopy. J Am Chem Soc (2005) 1.06
Evidence for pseudoknot formation of class I preQ1 riboswitch aptamers. Chembiochem (2009) 1.05
Atomic mutagenesis reveals A2660 of 23S ribosomal RNA as key to EF-G GTPase activation. Nat Chem Biol (2010) 1.01
Long non-coding RNAs as targets for cytosine methylation. RNA Biol (2013) 1.00
5-Fluoro pyrimidines: labels to probe DNA and RNA secondary structures by 1D 19F NMR spectroscopy. Nucleic Acids Res (2009) 0.99
A general approach for the identification of site-specific RNA binders by 19F NMR spectroscopy: proof of concept. Angew Chem Int Ed Engl (2006) 0.96
Non-hydrolyzable RNA-peptide conjugates: a powerful advance in the synthesis of mimics for 3'-peptidyl tRNA termini. Angew Chem Int Ed Engl (2009) 0.96
Synthesis, oxidation behavior, crystallization and structure of 2'-methylseleno guanosine containing RNAs. J Am Chem Soc (2006) 0.95
19F NMR spectroscopy for the analysis of RNA secondary structure populations. J Am Chem Soc (2008) 0.94
Chemical synthesis of site-specifically 2'-azido-modified RNA and potential applications for bioconjugation and RNA interference. Chembiochem (2011) 0.94
2'-Azido RNA, a versatile tool for chemical biology: synthesis, X-ray structure, siRNA applications, click labeling. ACS Chem Biol (2012) 0.93
Escherichia coli ribosomal protein S1 unfolds structured mRNAs onto the ribosome for active translation initiation. PLoS Biol (2013) 0.91
Triggering of RNA secondary structures by a functionalized nucleobase. Angew Chem Int Ed Engl (2004) 0.91
A fast selenium derivatization strategy for crystallization and phasing of RNA structures. RNA (2009) 0.91
Efficient access to nonhydrolyzable initiator tRNA based on the synthesis of 3'-azido-3'-deoxyadenosine RNA. Angew Chem Int Ed Engl (2010) 0.89
Efficient access to 3'-terminal azide-modified RNA for inverse click-labeling patterns. Bioconjug Chem (2013) 0.89
Use of aptamer tagging to identify in vivo protein binding partners of small regulatory RNAs. Methods Mol Biol (2012) 0.88
Binding of aminoglycoside antibiotics to the duplex form of the HIV-1 genomic RNA dimerization initiation site. Angew Chem Int Ed Engl (2008) 0.88
Thermodynamics of HIV-1 reverse transcriptase in action elucidates the mechanism of action of non-nucleoside inhibitors. J Am Chem Soc (2013) 0.86
2'-Methylseleno-modified oligoribonucleotides for X-ray crystallography synthesized by the ACE RNA solid-phase approach. Nucleic Acids Res (2007) 0.85
Reliable semi-synthesis of hydrolysis-resistant 3'-peptidyl-tRNA conjugates containing genuine tRNA modifications. Nucleic Acids Res (2010) 0.84
Native chemical ligation of hydrolysis-resistant 3'-peptidyl-tRNA mimics. J Am Chem Soc (2011) 0.84
2'-SCF3 uridine-a powerful label for probing structure and function of RNA by 19F NMR spectroscopy. Angew Chem Int Ed Engl (2012) 0.84
Selective desulfurization significantly expands sequence variety of 3'-peptidyl-tRNA mimics obtained by native chemical ligation. Chembiochem (2012) 0.83
Ligand-detected relaxation dispersion NMR spectroscopy: dynamics of preQ1-RNA binding. Angew Chem Int Ed Engl (2014) 0.83
Screening mutant libraries of T7 RNA polymerase for candidates with increased acceptance of 2'-modified nucleotides. Chem Commun (Camb) (2012) 0.82
Functionalized polystyrene supports for solid-phase synthesis of glycyl-, alanyl-, and isoleucyl-RNA conjugates as hydrolysis-resistant mimics of peptidyl-tRNAs. Bioorg Med Chem (2011) 0.82
Enzymatic ligation strategies for the preparation of purine riboswitches with site-specific chemical modifications. Methods Mol Biol (2009) 0.82
Effects of N2,N2-dimethylguanosine on RNA structure and stability: crystal structure of an RNA duplex with tandem m2 2G:A pairs. RNA (2008) 0.82
Surprising base pairing and structural properties of 2'-trifluoromethylthio-modified ribonucleic acids. J Am Chem Soc (2014) 0.81
The synthesis of methylated, phosphorylated, and phosphonated 3'-aminoacyl-tRNA(Sec) mimics. Chemistry (2013) 0.80
New insights into gene regulation--high-resolution structures of cobalamin riboswitches. Angew Chem Int Ed Engl (2013) 0.79
Preparation of 2'-deoxy-2'-methylseleno-modified phosphoramidites and RNA. Curr Protoc Nucleic Acid Chem (2007) 0.78
Deoxyribozyme-based, semisynthetic access to stable peptidyl-tRNAs exemplified by tRNAVal carrying a macrolide antibiotic resistance peptide. Methods Mol Biol (2012) 0.78
RNA biophysics: a three-state balancing act. Nature (2013) 0.76
The synthesis of 2'-methylseleno adenosine and guanosine 5'-triphosphates. Bioorg Med Chem (2012) 0.75
Chasing after antibiotic leads. Chem Biol (2009) 0.75
Use of SHAPE to select 2AP substitution sites for RNA-ligand interactions and dynamics studies. Methods Mol Biol (2014) 0.75
2'-Methylseleno modified oligoribonucleotides synthesized for X-ray crystallography. Nucleic Acids Symp Ser (Oxf) (2008) 0.75
Temperature-dependent changes of RNA secondary structures monitored by 19F-NMR spectroscopy. Nucleic Acids Symp Ser (Oxf) (2008) 0.75