Published in J Mol Biol on January 17, 2003
Post-transcriptional nucleotide modification and alternative folding of RNA. Nucleic Acids Res (2006) 2.34
Ligand-induced folding of the thiM TPP riboswitch investigated by a structure-based fluorescence spectroscopic approach. Nucleic Acids Res (2007) 1.79
Rich RNA Structure Landscapes Revealed by Mutate-and-Map Analysis. PLoS Comput Biol (2015) 1.44
Folding of a transcriptionally acting preQ1 riboswitch. Proc Natl Acad Sci U S A (2010) 1.34
Chemical engineering of the peptidyl transferase center reveals an important role of the 2'-hydroxyl group of A2451. Nucleic Acids Res (2005) 1.29
Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme. Nucleic Acids Res (2007) 1.11
Vfold: a web server for RNA structure and folding thermodynamics prediction. PLoS One (2014) 1.02
An RNA hairpin to G-quadruplex conformational transition. J Am Chem Soc (2012) 1.00
5-Fluoro pyrimidines: labels to probe DNA and RNA secondary structures by 1D 19F NMR spectroscopy. Nucleic Acids Res (2009) 0.99
Probing RNA dynamics via longitudinal exchange and CPMG relaxation dispersion NMR spectroscopy using a sensitive 13C-methyl label. Nucleic Acids Res (2011) 0.97
The "Speedy" Synthesis of Atom-Specific (15)N Imino/Amido-Labeled RNA. Chemistry (2015) 0.90
2'-Methylseleno-modified oligoribonucleotides for X-ray crystallography synthesized by the ACE RNA solid-phase approach. Nucleic Acids Res (2007) 0.85
2'-SCF3 uridine-a powerful label for probing structure and function of RNA by 19F NMR spectroscopy. Angew Chem Int Ed Engl (2012) 0.84
RNA phosphodiester backbone dynamics of a perdeuterated cUUCGg tetraloop RNA from phosphorus-31 NMR relaxation analysis. J Biomol NMR (2009) 0.81
Conservation of mRNA secondary structures may filter out mutations in Escherichia coli evolution. Nucleic Acids Res (2013) 0.80
A novel paramagnetic relaxation enhancement tag for nucleic acids: a tool to study structure and dynamics of RNA. ACS Chem Biol (2013) 0.80
Fast, approximate kinetics of RNA folding. J Comput Biol (2015) 0.79
Insights into the Stress Response Triggered by Kasugamycin in Escherichia coli. Antibiotics (Basel) (2016) 0.75
Structural basis for discriminative regulation of gene expression by adenine- and guanine-sensing mRNAs. Chem Biol (2004) 5.44
Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation. Nat Struct Mol Biol (2005) 2.50
Structural and functional insights into 5'-ppp RNA pattern recognition by the innate immune receptor RIG-I. Nat Struct Mol Biol (2010) 2.13
Ligand-induced folding of the adenosine deaminase A-riboswitch and implications on riboswitch translational control. Chembiochem (2007) 2.12
Nascent peptide in the ribosome exit tunnel affects functional properties of the A-site of the peptidyl transferase center. Mol Cell (2011) 1.96
Conformational capture of the SAM-II riboswitch. Nat Chem Biol (2011) 1.84
Ligand-induced folding of the thiM TPP riboswitch investigated by a structure-based fluorescence spectroscopic approach. Nucleic Acids Res (2007) 1.79
The role of 23S ribosomal RNA residue A2451 in peptide bond synthesis revealed by atomic mutagenesis. Chem Biol (2008) 1.79
The dynamic nature of RNA as key to understanding riboswitch mechanisms. Acc Chem Res (2011) 1.39
Folding of a transcriptionally acting preQ1 riboswitch. Proc Natl Acad Sci U S A (2010) 1.34
Chemical engineering of the peptidyl transferase center reveals an important role of the 2'-hydroxyl group of A2451. Nucleic Acids Res (2005) 1.29
Pseudoknot preorganization of the preQ1 class I riboswitch. J Am Chem Soc (2012) 1.20
Efficient ribosomal peptidyl transfer critically relies on the presence of the ribose 2'-OH at A2451 of 23S rRNA. J Am Chem Soc (2006) 1.20
Syntheses of RNAs with up to 100 nucleotides containing site-specific 2'-methylseleno labels for use in X-ray crystallography. J Am Chem Soc (2005) 1.18
An intact ribose moiety at A2602 of 23S rRNA is key to trigger peptidyl-tRNA hydrolysis during translation termination. Nucleic Acids Res (2007) 1.15
Chemical synthesis of selenium-modified oligoribonucleotides and their enzymatic ligation leading to an U6 SnRNA stem-loop segment. J Am Chem Soc (2004) 1.15
The preparation of site-specifically modified riboswitch domains as an example for enzymatic ligation of chemically synthesized RNA fragments. Nat Protoc (2008) 1.15
Stem cells are differentially regulated during development, regeneration and homeostasis in flatworms. Dev Biol (2009) 1.11
Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme. Nucleic Acids Res (2007) 1.11
Tuning a riboswitch response through structural extension of a pseudoknot. Proc Natl Acad Sci U S A (2013) 1.09
Folding and ligand recognition of the TPP riboswitch aptamer at single-molecule resolution. Proc Natl Acad Sci U S A (2013) 1.08
Ribose 2'-F labeling: a simple tool for the characterization of RNA secondary structure equilibria by 19F NMR spectroscopy. J Am Chem Soc (2005) 1.06
Evidence for pseudoknot formation of class I preQ1 riboswitch aptamers. Chembiochem (2009) 1.05
Atomic mutagenesis reveals A2660 of 23S ribosomal RNA as key to EF-G GTPase activation. Nat Chem Biol (2010) 1.01
Long non-coding RNAs as targets for cytosine methylation. RNA Biol (2013) 1.00
5-Fluoro pyrimidines: labels to probe DNA and RNA secondary structures by 1D 19F NMR spectroscopy. Nucleic Acids Res (2009) 0.99
Non-hydrolyzable RNA-peptide conjugates: a powerful advance in the synthesis of mimics for 3'-peptidyl tRNA termini. Angew Chem Int Ed Engl (2009) 0.96
A general approach for the identification of site-specific RNA binders by 19F NMR spectroscopy: proof of concept. Angew Chem Int Ed Engl (2006) 0.96
A powerful approach for the selection of 2-aminopurine substitution sites to investigate RNA folding. J Am Chem Soc (2011) 0.96
Synthesis, oxidation behavior, crystallization and structure of 2'-methylseleno guanosine containing RNAs. J Am Chem Soc (2006) 0.95
19F NMR spectroscopy for the analysis of RNA secondary structure populations. J Am Chem Soc (2008) 0.94
Chemical synthesis of site-specifically 2'-azido-modified RNA and potential applications for bioconjugation and RNA interference. Chembiochem (2011) 0.94
2'-Azido RNA, a versatile tool for chemical biology: synthesis, X-ray structure, siRNA applications, click labeling. ACS Chem Biol (2012) 0.93
Escherichia coli ribosomal protein S1 unfolds structured mRNAs onto the ribosome for active translation initiation. PLoS Biol (2013) 0.91
A fast selenium derivatization strategy for crystallization and phasing of RNA structures. RNA (2009) 0.91
Triggering of RNA secondary structures by a functionalized nucleobase. Angew Chem Int Ed Engl (2004) 0.91
Efficient access to 3'-terminal azide-modified RNA for inverse click-labeling patterns. Bioconjug Chem (2013) 0.89
Efficient access to nonhydrolyzable initiator tRNA based on the synthesis of 3'-azido-3'-deoxyadenosine RNA. Angew Chem Int Ed Engl (2010) 0.89
Binding of aminoglycoside antibiotics to the duplex form of the HIV-1 genomic RNA dimerization initiation site. Angew Chem Int Ed Engl (2008) 0.88
Thermodynamics of HIV-1 reverse transcriptase in action elucidates the mechanism of action of non-nucleoside inhibitors. J Am Chem Soc (2013) 0.86
2'-Methylseleno-modified oligoribonucleotides for X-ray crystallography synthesized by the ACE RNA solid-phase approach. Nucleic Acids Res (2007) 0.85
2'-SCF3 uridine-a powerful label for probing structure and function of RNA by 19F NMR spectroscopy. Angew Chem Int Ed Engl (2012) 0.84
Native chemical ligation of hydrolysis-resistant 3'-peptidyl-tRNA mimics. J Am Chem Soc (2011) 0.84
Reliable semi-synthesis of hydrolysis-resistant 3'-peptidyl-tRNA conjugates containing genuine tRNA modifications. Nucleic Acids Res (2010) 0.84
Selective desulfurization significantly expands sequence variety of 3'-peptidyl-tRNA mimics obtained by native chemical ligation. Chembiochem (2012) 0.83
Ligand-detected relaxation dispersion NMR spectroscopy: dynamics of preQ1-RNA binding. Angew Chem Int Ed Engl (2014) 0.83
Screening mutant libraries of T7 RNA polymerase for candidates with increased acceptance of 2'-modified nucleotides. Chem Commun (Camb) (2012) 0.82
Enzymatic ligation strategies for the preparation of purine riboswitches with site-specific chemical modifications. Methods Mol Biol (2009) 0.82
Functionalized polystyrene supports for solid-phase synthesis of glycyl-, alanyl-, and isoleucyl-RNA conjugates as hydrolysis-resistant mimics of peptidyl-tRNAs. Bioorg Med Chem (2011) 0.82
Effects of N2,N2-dimethylguanosine on RNA structure and stability: crystal structure of an RNA duplex with tandem m2 2G:A pairs. RNA (2008) 0.82
Surprising base pairing and structural properties of 2'-trifluoromethylthio-modified ribonucleic acids. J Am Chem Soc (2014) 0.81
The synthesis of methylated, phosphorylated, and phosphonated 3'-aminoacyl-tRNA(Sec) mimics. Chemistry (2013) 0.80
New insights into gene regulation--high-resolution structures of cobalamin riboswitches. Angew Chem Int Ed Engl (2013) 0.79
Deoxyribozyme-based, semisynthetic access to stable peptidyl-tRNAs exemplified by tRNAVal carrying a macrolide antibiotic resistance peptide. Methods Mol Biol (2012) 0.78
RNA biophysics: a three-state balancing act. Nature (2013) 0.76
The synthesis of 2'-methylseleno adenosine and guanosine 5'-triphosphates. Bioorg Med Chem (2012) 0.75
Use of SHAPE to select 2AP substitution sites for RNA-ligand interactions and dynamics studies. Methods Mol Biol (2014) 0.75
Chasing after antibiotic leads. Chem Biol (2009) 0.75
Temperature-dependent changes of RNA secondary structures monitored by 19F-NMR spectroscopy. Nucleic Acids Symp Ser (Oxf) (2008) 0.75
2'-Methylseleno modified oligoribonucleotides synthesized for X-ray crystallography. Nucleic Acids Symp Ser (Oxf) (2008) 0.75