Published in Diabetes on June 01, 1990
Islet amyloid in type 2 diabetes, and the toxic oligomer hypothesis. Endocr Rev (2008) 2.79
Endoplasmic reticulum stress and type 2 diabetes. Annu Rev Biochem (2012) 2.10
Spontaneous diabetes mellitus in transgenic mice expressing human islet amyloid polypeptide. Proc Natl Acad Sci U S A (1996) 1.81
Pancreatic function, type 2 diabetes, and metabolism in aging. Int J Endocrinol (2012) 1.77
Evidence for proteotoxicity in beta cells in type 2 diabetes: toxic islet amyloid polypeptide oligomers form intracellularly in the secretory pathway. Am J Pathol (2009) 1.53
Amylin acts in the central nervous system to increase sympathetic nerve activity. Endocrinology (2013) 1.47
Pancreatic signals controlling food intake; insulin, glucagon and amylin. Philos Trans R Soc Lond B Biol Sci (2006) 1.27
Pancreatic beta-cell granule peptides form heteromolecular complexes which inhibit islet amyloid polypeptide fibril formation. Biochem J (2004) 1.22
Islets in type 2 diabetes: in honor of Dr. Robert C. Turner. Diabetes (2008) 1.11
β-cell dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptide-induced UCH-L1 deficiency. Diabetes (2010) 1.10
Human-IAPP disrupts the autophagy/lysosomal pathway in pancreatic β-cells: protective role of p62-positive cytoplasmic inclusions. Cell Death Differ (2010) 1.07
Adaptations in pulsatile insulin secretion, hepatic insulin clearance, and beta-cell mass to age-related insulin resistance in rats. Am J Physiol Endocrinol Metab (2008) 1.03
Amyloid formation in human IAPP transgenic mouse islets and pancreas, and human pancreas, is not associated with endoplasmic reticulum stress. Diabetologia (2009) 1.02
Ionic strength effects on amyloid formation by amylin are a complicated interplay among Debye screening, ion selectivity, and Hofmeister effects. Biochemistry (2012) 0.99
Obesity treatment: novel peripheral targets. Br J Clin Pharmacol (2009) 0.95
Insulin upstream factor 1 and a novel ubiquitous factor bind to the human islet amyloid polypeptide/amylin gene promoter. Biochem J (1996) 0.95
Intestinal feedback signaling and satiety. Physiol Behav (2011) 0.94
How type II diabetes-related islet amyloid polypeptide damages lipid bilayers. Biophys J (2012) 0.94
Amylin receptor signaling in the ventral tegmental area is physiologically relevant for the control of food intake. Neuropsychopharmacology (2013) 0.90
Central amylin acts as an adiposity signal to control body weight and energy expenditure. Physiol Behav (2010) 0.89
Associations of amylin with inflammatory markers and metabolic syndrome in apparently healthy Chinese. PLoS One (2011) 0.88
An islet in distress: β cell failure in type 2 diabetes. J Diabetes Investig (2010) 0.88
Integration of satiety signals by the central nervous system. Curr Biol (2013) 0.87
A feline model of experimentally induced islet amyloidosis. Am J Pathol (2000) 0.84
Metabolic and hormonal signatures in pre-manifest and manifest Huntington's disease patients. Front Physiol (2014) 0.84
Endoplasmic reticulum overcrowding as a mechanism of beta-cell dysfunction in diabetes. Biophys J (2010) 0.84
Salmon calcitonin reduces food intake through changes in meal sizes in male rhesus monkeys. Am J Physiol Regul Integr Comp Physiol (2008) 0.81
Degradation of islet amyloid polypeptide by neprilysin. Diabetologia (2012) 0.81
Interactions of gastrointestinal peptides: ghrelin and its anorexigenic antagonists. Int J Pept (2010) 0.80
Membrane Curvature-sensing and Curvature-inducing Activity of Islet Amyloid Polypeptide and Its Implications for Membrane Disruption. J Biol Chem (2015) 0.77
Amylin receptor signaling in the nucleus accumbens negatively modulates μ-opioid-driven feeding. Neuropsychopharmacology (2014) 0.77
Obesity pharmacotherapy: current perspectives and future directions. Curr Cardiol Rev (2013) 0.77
CHOP Contributes to, But Is Not the Only Mediator of, IAPP Induced β-Cell Apoptosis. Mol Endocrinol (2016) 0.77
Differential effect of amylin on endothelial-dependent vasodilation in mesenteric arteries from control and insulin resistant rats. PLoS One (2015) 0.77
Antipsychotic-like actions of the satiety peptide, amylin, in ventral striatal regions marked by overlapping calcitonin receptor and RAMP-1 gene expression. J Neurosci (2014) 0.76
Dissecting the Syndrome of Schizophrenia: Progress toward Clinically Useful Biomarkers. Schizophr Res Treatment (2011) 0.76
Histopathological changes in the pancreas from a spontaneous hyperglycemic cynomolgus monkey. J Toxicol Pathol (2012) 0.76
Plasma amylin and insulin concentrations in normoglycemic and hyperglycemic cats. Can Vet J (1996) 0.76
Membrane remodeling by amyloidogenic and non-amyloidogenic proteins studied by EPR. J Magn Reson (2017) 0.75
Neuroendocrine hormone amylin in diabetes. World J Diabetes (2016) 0.75
Diabetes mellitus. Postgrad Med J (1990) 0.75
Screening for depression in well older adults: evaluation of a short form of the CES-D (Center for Epidemiologic Studies Depression Scale). Am J Prev Med (1994) 18.43
The Sickness Impact Profile: development and final revision of a health status measure. Med Care (1981) 18.20
Beta-galactosidase gene fusions for analyzing gene expression in escherichia coli and yeast. Methods Enzymol (1983) 14.92
Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: indirect evidence for islet regeneration? Diabetologia (2005) 4.61
Development of the kidney disease quality of life (KDQOL) instrument. Qual Life Res (1994) 4.37
T-cell co-stimulation through B7RP-1 and ICOS. Nature (1999) 4.20
Release of surface enzymes in Enterobacteriaceae by osmotic shock. J Bacteriol (1967) 4.05
The terminal a sequence of the herpes simplex virus genome contains the promoter of a gene located in the repeat sequences of the L component. J Virol (1986) 3.63
Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice. Proc Natl Acad Sci U S A (2000) 3.37
Dose-response characteristics for effects of insulin on production and utilization of glucose in man. Am J Physiol (1981) 3.30
Replication of semliki forest virus: three forms of viral RNA produced during infection. Proc Natl Acad Sci U S A (1966) 3.23
Human platelet-derived growth factor. Purification and resolution into two active protein fractions. J Biol Chem (1981) 3.21
Results of treatment of 385 patients with peritoneal surface spread of appendiceal malignancy. Ann Surg Oncol (1999) 3.21
In vivo formation of gene fusions encoding hybrid beta-galactosidase proteins in one step with a transposable Mu-lac transducing phage. Proc Natl Acad Sci U S A (1984) 3.06
Platelet factor 4 is chemotactic for neutrophils and monocytes. Proc Natl Acad Sci U S A (1981) 3.03
Adaptive changes in pancreatic beta cell fractional area and beta cell turnover in human pregnancy. Diabetologia (2010) 2.91
Identification by antibody to a synthetic peptide of a protein specified by a diploid gene located in the terminal repeats of the L component of herpes simplex virus genome. J Virol (1986) 2.71
Liver iron stores in patients with non-insulin-dependent diabetes mellitus. Mayo Clin Proc (1994) 2.71
Influence of body fat distribution on free fatty acid metabolism in obesity. J Clin Invest (1989) 2.69
Notch activity influences the alphabeta versus gammadelta T cell lineage decision. Cell (1997) 2.66
Functional domains within the a sequence involved in the cleavage-packaging of herpes simplex virus DNA. J Virol (1986) 2.61
Replication, establishment of latency, and induced reactivation of herpes simplex virus gamma 1 34.5 deletion mutants in rodent models. J Clin Invest (1993) 2.59
Pancreas volumes in humans from birth to age one hundred taking into account sex, obesity, and presence of type-2 diabetes. Clin Anat (2007) 2.58
Expression of a preproinsulin-beta-galactosidase gene fusion in mammalian cells. Proc Natl Acad Sci U S A (1983) 2.57
Thymosin alpha1: isolation and sequence analysis of an immunologically active thymic polypeptide. Proc Natl Acad Sci U S A (1977) 2.45
Cortisol-induced insulin resistance in man: impaired suppression of glucose production and stimulation of glucose utilization due to a postreceptor detect of insulin action. J Clin Endocrinol Metab (1982) 2.45
An activated form of Notch influences the choice between CD4 and CD8 T cell lineages. Cell (1996) 2.42
Identification and characterization of a self-regulated repressor of translocation of the Tn3 element. Proc Natl Acad Sci U S A (1979) 2.37
Filamin A, the Arp2/3 complex, and the morphology and function of cortical actin filaments in human melanoma cells. J Cell Biol (2001) 2.29
Transposition protein of Tn3: identification and characterisation of an essential repressor-controlled gene product. Nature (1980) 2.24
Urinary excretion of histamine in renal transplant patients. Surg Gynecol Obstet (1968) 2.16
Lack of suppression of glucagon contributes to postprandial hyperglycemia in subjects with type 2 diabetes mellitus. J Clin Endocrinol Metab (2000) 2.15
Evidence for a protective role of pulmonary surfactant protein D (SP-D) against influenza A viruses. J Clin Invest (1994) 2.14
Isomerization of herpes simplex virus 1 genome: identification of the cis-acting and recombination sites within the domain of the a sequence. Cell (1985) 2.12
Induction of midbrain dopaminergic neurons by Sonic hedgehog. Neuron (1995) 2.08
Patient requests and expectations. Definitions and clinical applications. Med Care (1984) 2.06
Ultralight metallic microlattices. Science (2011) 2.05
Morbidity and mortality analysis of 200 treatments with cytoreductive surgery and hyperthermic intraoperative intraperitoneal chemotherapy using the coliseum technique. Ann Surg Oncol (1999) 2.02
Pseudomyxoma peritonei syndrome. Adv Surg (1996) 1.99
(D-Ala2)-Met-enkephalinamide: a potent, long-lasting synthetic pentapeptide analgesic. Science (1976) 1.95
Reconciliation of international administrative coding systems for comparison of colorectal surgery outcome. Colorectal Dis (2014) 1.91
The role of growth hormone in the development of diabetic retinopathy. Diabetes Care (1994) 1.91
ErbB-3 and ErbB-4 function as the respective low and high affinity receptors of all Neu differentiation factor/heregulin isoforms. J Biol Chem (1994) 1.88
Transformation of NIH 3T3 cells by HER3 or HER4 receptors requires the presence of HER1 or HER2. J Biol Chem (1996) 1.87
Birth defects after maternal exposure to corticosteroids: prospective cohort study and meta-analysis of epidemiological studies. Teratology (2000) 1.78
Use and misuse of metered-dose inhalers by patients with chronic lung disease. A controlled, randomized trial of two instruction methods. Am Rev Respir Dis (1989) 1.75
Site-specific DNA deletions occurring adjacent to the termini of a transposable ampicillin resistance element (Tn3). J Mol Biol (1977) 1.74
Modestly increased beta cell apoptosis but no increased beta cell replication in recent-onset type 1 diabetic patients who died of diabetic ketoacidosis. Diabetologia (2007) 1.73
Mechanism and significance of insulin resistance in non-insulin-dependent diabetes mellitus. Diabetes (1981) 1.73
Adrenergic mechanisms for the effects of epinephrine on glucose production and clearance in man. J Clin Invest (1980) 1.71
Methamphetamine causes widespread apoptosis in the mouse brain: evidence from using an improved TUNEL histochemical method. Brain Res Mol Brain Res (2001) 1.71
Pediatric clinicians' support for parents makes a difference: an outcome-based analysis of clinician-parent interaction. Pediatrics (1984) 1.70
Implementing preventive care in clinical practice. II. Problems for managers, clinicians and patients. Med Care Rev (1981) 1.66
Postprandial hyperglycemia in patients with noninsulin-dependent diabetes mellitus. Role of hepatic and extrahepatic tissues. J Clin Invest (1986) 1.61
Effects of type 2 diabetes on the ability of insulin and glucose to regulate splanchnic and muscle glucose metabolism: evidence for a defect in hepatic glucokinase activity. Diabetes (2000) 1.60
Effects of cisapride on QT interval in children. J Pediatr (1998) 1.59
Purification and biochemical characterization of CP4 (SP-D), a collagenous surfactant-associated protein. Biochemistry (1989) 1.55
Methods for assessment of the rate of onset and offset of insulin action during nonsteady state in humans. Am J Physiol (1993) 1.52
Outcome-based doctor-patient interaction anaylsis: I. Comparison of techniques. Med Care (1982) 1.52
Molecular structure of pulmonary surfactant protein D (SP-D). J Biol Chem (1994) 1.51
Problems and prospects for health services research on provider-patient communication. Med Care (1985) 1.51
Surfactant protein D is a divalent cation-dependent carbohydrate-binding protein. J Biol Chem (1990) 1.51
Drug- and toxin-induced rhabdomyolysis. Ann Emerg Med (1989) 1.51
An exploration of somatization among Asian refugees and immigrants in primary care. Am J Public Health (1985) 1.49
Surfactant protein-D modulates interaction of Pneumocystis carinii with alveolar macrophages. J Lab Clin Med (1995) 1.49
Interactions of recombinant human pulmonary surfactant protein D and SP-D multimers with influenza A. Am J Physiol (1996) 1.49
Acute enlargement and subsequent rupture of an abdominal aortic aneurysm in a patient receiving chemotherapy for pancreatic carcinoma. J Vasc Surg (2000) 1.48
Type II collagen screening in the human chondrodysplasias. Am J Med Genet (1989) 1.48
The relationship of attitude changes to compliance with influenza immunization. A prospective study. Med Care (1985) 1.47
Esophageal symptoms, manometry, and histology before and after antireflux surgery: a long-term follow-up study. Gastroenterology (1979) 1.46
Tanycytomas: a newly characterized hypothalamic-suprasellar and ventricular tumor. AJNR Am J Neuroradiol (2003) 1.45
Studies of the specificity and control of transposition of the Tn3 element. Cold Spring Harb Symp Quant Biol (1979) 1.45
Evaluation of genetically engineered herpes simplex viruses as oncolytic agents for human malignant brain tumors. Cancer Res (1997) 1.45
Measurements of glucose control. Diabetes Care (1987) 1.45
Indirect detection of intraoperative carbon monoxide exposure by mass spectrometry during isoflurane anesthesia. Anesthesiology (1995) 1.44
Assessment of the postprandial pattern of glucose metabolism in nondiabetic subjects and patients with non-insulin-dependent diabetes mellitus using a simultaneous infusion of [2(3)H] and [3(3)H] glucose. Metabolism (1989) 1.42
Maternal recall of infant feeding events is accurate. J Epidemiol Community Health (1992) 1.42
Comparison of genetically engineered herpes simplex viruses for the treatment of brain tumors in a scid mouse model of human malignant glioma. Proc Natl Acad Sci U S A (1995) 1.41
The application of genetically engineered herpes simplex viruses to the treatment of experimental brain tumors. Proc Natl Acad Sci U S A (1996) 1.41
A cross-cultural comparison of health status values. Am J Public Health (1985) 1.39
Effects of growth hormone on insulin action in man. Mechanisms of insulin resistance, impaired suppression of glucose production, and impaired stimulation of glucose utilization. Diabetes (1982) 1.39
Depressed skull fractures in children secondary to skull clamp fixation devices. Pediatr Neurosurg (1994) 1.38
A 35 amino acid fragment of leptin inhibits feeding in the rat. Endocrinology (1996) 1.38
Solution structure of Apaf-1 CARD and its interaction with caspase-9 CARD: a structural basis for specific adaptor/caspase interaction. Proc Natl Acad Sci U S A (1999) 1.38
Evaluation of breast self-examination beliefs using a decision model. West J Nurs Res (1993) 1.38
Screening for noncompliance among patients with hypertension: is self-report the best available measure? Med Care (1981) 1.37
Production of insulin resistance by hyperinsulinaemia in man. Diabetologia (1985) 1.36
Effects of plasma glucose concentration on glucose utilization and glucose clearance in normal man. Diabetes (1981) 1.35
Systemic and regional free fatty acid metabolism in type 2 diabetes. Am J Physiol Endocrinol Metab (2001) 1.33
Amino acid sequence of rabbit muscle aldolase and the structure of the active center. Science (1974) 1.32
Recombinant pulmonary surfactant protein D. Post-translational modification and molecular assembly. J Biol Chem (1994) 1.32
Extrapancreatic effects of GIP and GLP-1. Horm Metab Res (2005) 1.32
Cardiovascular regulatory actions of the hypocretins in brain. Brain Res (1999) 1.31
Surfactant protein D enhances phagocytosis and killing of unencapsulated phase variants of Klebsiella pneumoniae. Infect Immun (2001) 1.30