Published in J Clin Endocrinol Metab on June 01, 1990
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Ethnic differences in insulin action in obese African-American and Latino adolescents. J Clin Endocrinol Metab (2010) 1.40
Subcutaneous adipose tissue macrophage infiltration is associated with hepatic and visceral fat deposition, hyperinsulinemia, and stimulation of NF-κB stress pathway. Diabetes (2011) 1.24
Ethnic differences in pancreatic fat accumulation and its relationship with other fat depots and inflammatory markers. Diabetes Care (2011) 1.09
Fasting indicators of insulin sensitivity: effects of ethnicity and pubertal status. Diabetes Care (2011) 0.91
Insulin sensitivity and β-cell function in adults born preterm and their children. Diabetes (2012) 0.89
Effects of a randomized maintenance intervention on adiposity and metabolic risk factors in overweight minority adolescents. Pediatr Obes (2012) 0.87
Sociocultural and socioeconomic influences on type 2 diabetes risk in overweight/obese African-American and Latino-American children and adolescents. J Obes (2013) 0.86
Role of adiponectin and leptin on body development in infants during the first year of life. Ital J Pediatr (2010) 0.86
Feasibility of intravenous glucose tolerance testing prior to puberty. Int J Pediatr Obes (2010) 0.85
CRP is related to higher leptin levels in minority peripubertal females regardless of adiposity levels. Obesity (Silver Spring) (2011) 0.81
Decreased insulin response to glucose in islet cell antibody-negative siblings of type 1 diabetic children. J Clin Invest (1993) 0.80
Pre-pubertal children born post-term have reduced insulin sensitivity and other markers of the metabolic syndrome. PLoS One (2013) 0.80
Earlier Menarche Is Associated with Lower Insulin Sensitivity and Increased Adiposity in Young Adult Women. PLoS One (2015) 0.75
Quantitative estimation of insulin sensitivity. Am J Physiol (1979) 7.37
Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study. Lancet (1992) 6.28
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Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function. Diabetes (1993) 5.70
Assessment of insulin sensitivity in vivo. Endocr Rev (1985) 4.21
Mapping genes for NIDDM. Design of the Finland-United States Investigation of NIDDM Genetics (FUSION) Study. Diabetes Care (1998) 3.99
MINMOD: a computer program to calculate insulin sensitivity and pancreatic responsivity from the frequently sampled intravenous glucose tolerance test. Comput Methods Programs Biomed (1986) 3.54
Estimation of endogenous glucose production during hyperinsulinemic-euglycemic glucose clamps. Comparison of unlabeled and labeled exogenous glucose infusates. Diabetes (1987) 2.95
Equivalence of the insulin sensitivity index in man derived by the minimal model method and the euglycemic glucose clamp. J Clin Invest (1987) 2.81
Intensity and amount of physical activity in relation to insulin sensitivity: the Insulin Resistance Atherosclerosis Study. JAMA (1998) 2.56
Transplacental passage of insulin in pregnant women with insulin-dependent diabetes mellitus. Its role in fetal macrosomia. N Engl J Med (1990) 2.40
Insulin transport across capillaries is rate limiting for insulin action in dogs. J Clin Invest (1989) 2.32
Dietary restriction increases insulin sensitivity and lowers blood glucose in rhesus monkeys. Am J Physiol (1994) 2.13
Reduced sample number for calculation of insulin sensitivity and glucose effectiveness from the minimal model. Suitability for use in population studies. Diabetes (1993) 2.03
Measurement of "true" glucose production rates in infancy and childhood with 6,6-dideuteroglucose. Diabetes (1977) 2.02
ESPE/LWPES consensus statement on diabetic ketoacidosis in children and adolescents. Arch Dis Child (2004) 2.01
Type 2 diabetes: evidence for linkage on chromosome 20 in 716 Finnish affected sib pairs. Proc Natl Acad Sci U S A (1999) 1.91
Free fatty acid as a link in the regulation of hepatic glucose output by peripheral insulin. Diabetes (1995) 1.91
Dietary restriction and glucose regulation in aging rhesus monkeys: a follow-up report at 8.5 yr. Am J Physiol Endocrinol Metab (2001) 1.86
Familiality of quantitative metabolic traits in Finnish families with non-insulin-dependent diabetes mellitus. Finland-United States Investigation of NIDDM Genetics (FUSION) Study investigators. Hum Hered (1999) 1.76
A comparison between the minimal model and the glucose clamp in the assessment of insulin sensitivity across the spectrum of glucose tolerance. Insulin Resistance Atherosclerosis Study. Diabetes (1994) 1.73
Minimal model analysis of intravenous glucose tolerance test-derived insulin sensitivity in diabetic subjects. J Clin Endocrinol Metab (1990) 1.71
Role of glucose effectiveness in the determination of glucose tolerance. Diabetes Care (1996) 1.68
Quantitative estimation of beta cell sensitivity to glucose in the intact organism: a minimal model of insulin kinetics in the dog. Diabetes (1980) 1.67
Saturable transport of insulin from plasma into the central nervous system of dogs in vivo. A mechanism for regulated insulin delivery to the brain. J Clin Invest (1993) 1.67
Caloric restriction per se is a significant factor in improvements in glycemic control and insulin sensitivity during weight loss in obese NIDDM patients. Diabetes Care (1994) 1.67
Longitudinal compensation for fat-induced insulin resistance includes reduced insulin clearance and enhanced beta-cell response. Diabetes (2000) 1.63
Causal linkage between insulin suppression of lipolysis and suppression of liver glucose output in dogs. J Clin Invest (1996) 1.60
Dietary fat and insulin sensitivity in a triethnic population: the role of obesity. The Insulin Resistance Atherosclerosis Study (IRAS) Am J Clin Nutr (1997) 1.59
Diurnal variation in glucose tolerance. Cyclic suppression of insulin action and insulin secretion in normal-weight, but not obese, subjects. Diabetes (1992) 1.56
Cardiac septal hypertrophy in hyperinsulinemic infants. J Pediatr (1980) 1.55
Modified protocols improve insulin sensitivity estimation using the minimal model. Am J Physiol (1987) 1.54
Prolonged elevation of plasma free fatty acids impairs pancreatic beta-cell function in obese nondiabetic humans but not in individuals with type 2 diabetes. Diabetes (2000) 1.52
Insulin sensitivity and B-cell responsiveness to glucose during late pregnancy in lean and moderately obese women with normal glucose tolerance or mild gestational diabetes. Am J Obstet Gynecol (1990) 1.48
Insulin resistance in short children with intrauterine growth retardation. J Clin Endocrinol Metab (1997) 1.48
The functional and clinical roles of osteopontin in cancer and metastasis. Curr Mol Med (2001) 1.45
Insulin sensitivity index, acute insulin response, and glucose effectiveness in a population-based sample of 380 young healthy Caucasians. Analysis of the impact of gender, body fat, physical fitness, and life-style factors. J Clin Invest (1996) 1.45
Puberty decreases insulin sensitivity. J Pediatr (1987) 1.45
Pathogenesis of age-related glucose intolerance in man: insulin resistance and decreased beta-cell function. J Clin Endocrinol Metab (1985) 1.43
Insulin sensitivity and acute insulin response in African-Americans, non-Hispanic whites, and Hispanics with NIDDM: the Insulin Resistance Atherosclerosis Study. Diabetes (1997) 1.42
Ethnic differences in carotid wall thickness. The Insulin Resistance Atherosclerosis Study. Stroke (1996) 1.42
True precocious puberty complicating congenital adrenal hyperplasia: treatment with a luteinizing hormone-releasing hormone analog. J Clin Endocrinol Metab (1984) 1.40
Novel glucosensor for hypoglycemic detection localized to the portal vein. Diabetes (1997) 1.36
Kinetics and specificity of insulin uptake from plasma into cerebrospinal fluid. Am J Physiol (1990) 1.31
Acute enhancement of insulin secretion by FFA in humans is lost with prolonged FFA elevation. Am J Physiol (1999) 1.30
The insulin sensitivity index in nondiabetic man. Correlation between clamp-derived and IVGTT-derived values. Diabetes (1986) 1.30
Peripheral effects of insulin dominate suppression of fasting hepatic glucose production. Am J Physiol (1990) 1.29
Modeling error and apparent isotope discrimination confound estimation of endogenous glucose production during euglycemic glucose clamps. Diabetes (1988) 1.28
Relation of metabolic control to complications in diabetes mellitus. J Pediatr (1986) 1.26
Knock-in mutation of the distal four tyrosines of linker for activation of T cells blocks murine T cell development. J Exp Med (2001) 1.25
Insulin sensitivity from meal tolerance tests in normal subjects: a minimal model index. J Clin Endocrinol Metab (2000) 1.25
Influence of total vs. visceral fat on insulin action and secretion in African American and white children. Obes Res (2001) 1.25
Inhibition of lipolysis causes suppression of endogenous glucose production independent of changes in insulin. Am J Physiol Endocrinol Metab (2000) 1.24
Indirect effect of insulin to suppress endogenous glucose production is dominant, even with hyperglucagonemia. J Clin Invest (1997) 1.22
Transendothelial insulin transport is not saturable in vivo. No evidence for a receptor-mediated process. J Clin Invest (1996) 1.21
Intraportal glucose infusion matched to oral glucose absorption. Lack of evidence for "gut factor" involvement in hepatic glucose storage. Diabetes (1982) 1.20
Minimal modeling, partition analysis, and the estimation of insulin sensitivity. Fed Proc (1980) 1.18
The peroxisome proliferator-activated receptor-gamma2 Pro12A1a variant: association with type 2 diabetes and trait differences. Diabetes (2001) 1.17
Primacy of liver glucosensors in the sympathetic response to progressive hypoglycemia. Proc Natl Acad Sci U S A (1994) 1.15
Dynamics of glucose autoregulation in the isolated, blood-perfused canine liver. Am J Physiol (1974) 1.15
Glucose tolerance and insulin action in rats with renovascular hypertension. Hypertension (1991) 1.15
Diminished insulin sensitivity and increased insulin response in nonobese, nondiabetic Mexican Americans. Metabolism (1990) 1.14
Importance of hepatic glucoreceptors in sympathoadrenal response to hypoglycemia. Diabetes (1991) 1.12
Integrated control of hepatic glucose metabolism. Fed Proc (1977) 1.12
Electroretinographic responses following vitamin A therapy in A-beta-lipoproteinemia. Am J Ophthalmol (1972) 1.12
The contribution of insulin-dependent and insulin-independent glucose uptake to intravenous glucose tolerance in healthy human subjects. Diabetes (1994) 1.12
Evidence for entry of plasma insulin into cerebrospinal fluid through an intermediate compartment in dogs. Quantitative aspects and implications for transport. J Clin Invest (1991) 1.12
Pioglitazone increases insulin sensitivity, reduces blood glucose, insulin, and lipid levels, and lowers blood pressure, in obese, insulin-resistant rhesus monkeys. Diabetes (1994) 1.12
Pancreatic alpha and beta cell functions in cystic fibrosis. J Pediatr (1977) 1.10
Increased beta-cell secretory capacity as mechanism for islet adaptation to nicotinic acid-induced insulin resistance. Diabetes (1989) 1.09
Portal vein afferents are critical for the sympathoadrenal response to hypoglycemia. Diabetes (2000) 1.09
Importance of glucose per se to intravenous glucose tolerance. Comparison of the minimal-model prediction with direct measurements. Diabetes (1985) 1.09
Optimal segments: a method for smoothing tracer data to calculate metabolic fluxes. Am J Physiol (1983) 1.09
A genome-wide association scan for acute insulin response to glucose in Hispanic-Americans: the Insulin Resistance Atherosclerosis Family Study (IRAS FS). Diabetologia (2009) 1.08
Dose-response relationship between lymph insulin and glucose uptake reveals enhanced insulin sensitivity of peripheral tissues. Diabetes (1992) 1.08
Insulin gene expression and insulin synthesis in mammalian neuronal cells. J Biol Chem (1994) 1.08
Variation in the resistin gene is associated with obesity and insulin-related phenotypes in Finnish subjects. Diabetologia (2004) 1.07
Synergistic effect of portal glucose and glucagon-like peptide-1 to lower systemic glucose and stimulate counter-regulatory hormones. Diabetologia (2005) 1.07
Quantitative trait loci for abdominal fat and BMI in Hispanic-Americans and African-Americans: the IRAS Family study. Int J Obes (Lond) (2005) 1.06
Angiotensin II induces insulin resistance independent of changes in interstitial insulin. Am J Physiol (1999) 1.06
TNF-alpha downregulates murine hepatic growth hormone receptor expression by inhibiting Sp1 and Sp3 binding. J Clin Invest (2001) 1.05
Critical evaluation of the combined model approach for estimation of prehepatic insulin secretion. Am J Physiol (1998) 1.05
Intestinal adaptation after jejunoileal bypass in man. Am J Clin Nutr (1977) 1.04
Importance of transcapillary insulin transport to dynamics of insulin action after intravenous glucose. Am J Physiol (1994) 1.04
Hypoglycaemia following diabetes remission in patients with 6q24 methylation defects: expanding the clinical phenotype. Diabetologia (2012) 1.04
Demonstration of direct effects of growth hormone on neonatal cardiomyocytes. J Biol Chem (2001) 1.04
Carotid artery atherosclerosis in type-2 diabetic and nondiabetic subjects with and without symptomatic coronary artery disease (The Insulin Resistance Atherosclerosis Study). Am J Cardiol (2000) 1.03
Spontaneous and amino acid-stimulated glucagon secretion in the immediate postnatal period. Relation to glucose and insulin. J Clin Invest (1974) 1.02
Candidate loci for insulin sensitivity and disposition index from a genome-wide association analysis of Hispanic participants in the Insulin Resistance Atherosclerosis (IRAS) Family Study. Diabetologia (2009) 1.01
Hyperparathyroidism and low serum osteocalcin despite vitamin D replacement in primary biliary cirrhosis. J Clin Endocrinol Metab (1987) 1.01
Linear growth and growth hormonal responsiveness in treated congenital adrenal hyperplasia. Am J Dis Child (1971) 1.01
Calcium, vitamin D and parathyroid hormone relationships in pregnant Caucasian and Asian women and their neonates. Ann Clin Biochem (1987) 1.01
The pilot gland approach to the study of insulin secretory dynamics. Recent Prog Horm Res (1971) 1.01
Low insulin sensitivity is associated with clustering of cardiovascular disease risk factors. Am J Epidemiol (1997) 1.01
Relationship of insulin clearance and secretion to insulin sensitivity in non-diabetic Mexican Americans. Eur J Clin Invest (1992) 1.01
Improvements in glucose homeostasis in response to regular exercise are influenced by the PPARG Pro12Ala variant: results from the HERITAGE Family Study. Diabetologia (2009) 1.00
The role of liver glucosensors in the integrated sympathetic response induced by deep hypoglycemia in dogs. Diabetes (1994) 1.00