Statistical Analysis in Genetic Studies of Mental Illnesses.

PubWeight™: 0.79‹?›

🔗 View Article (PMID 21909187)

Published in Stat Sci on January 01, 2011

Authors

Heping Zhang1

Author Affiliations

1: Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520-8034.

Articles cited by this

PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet (2007) 209.92

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci U S A (2009) 54.68

Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet (1993) 51.42

Sequential tests for the detection of linkage. Am J Hum Genet (1955) 43.74

Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet (1998) 40.97

A general model for the genetic analysis of pedigree data. Hum Hered (1971) 40.17

Parametric and nonparametric linkage analysis: a unified multipoint approach. Am J Hum Genet (1996) 39.80

Construction of multilocus genetic linkage maps in humans. Proc Natl Acad Sci U S A (1987) 35.83

Complement factor H polymorphism in age-related macular degeneration. Science (2005) 31.10

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science (2006) 27.49

Estimation of the recombination fraction in human pedigrees: efficient computation of the likelihood for human linkage studies. Am J Hum Genet (1974) 23.66

Common genetic variation and human traits. N Engl J Med (2009) 21.03

A sibship test for linkage in the presence of association: the sib transmission/disequilibrium test. Am J Hum Genet (1998) 15.76

Diagnostic criteria for use in psychiatric research. Arch Gen Psychiatry (1972) 14.01

Implementing a unified approach to family-based tests of association. Genet Epidemiol (2000) 10.96

Robust variance-components approach for assessing genetic linkage in pedigrees. Am J Hum Genet (1994) 10.58

A unified approach to adjusting association tests for population admixture with arbitrary pedigree structure and arbitrary missing marker information. Hum Hered (2000) 10.32

A comparison of sib-pair linkage tests for disease susceptibility loci. Genet Epidemiol (1985) 9.70

MYH9 is associated with nondiabetic end-stage renal disease in African Americans. Nat Genet (2008) 9.50

Multipoint analysis of human quantitative genetic variation. Am J Hum Genet (1990) 9.09

MYH9 is a major-effect risk gene for focal segmental glomerulosclerosis. Nat Genet (2008) 9.00

Sequence variants in SLITRK1 are associated with Tourette's syndrome. Science (2005) 8.20

A test for linkage and association in general pedigrees: the pedigree disequilibrium test. Am J Hum Genet (2000) 7.70

Transmission-disequilibrium tests for quantitative traits. Am J Hum Genet (1997) 7.10

Extreme discordant sib pairs for mapping quantitative trait loci in humans. Science (1995) 7.00

A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization. Nat Genet (2006) 6.39

Genome-wide search for genes affecting the risk for alcohol dependence. Am J Med Genet (1998) 6.04

Familial transmission of substance use disorders. Arch Gen Psychiatry (1998) 4.57

A transmission disequilibrium test for quantitative trait loci. Hum Hered (1998) 4.41

A discordant-sibship test for disequilibrium and linkage: no need for parental data. Am J Hum Genet (1998) 4.32

Extended multipoint identity-by-descent analysis of human quantitative traits: efficiency, power, and modeling considerations. Am J Hum Genet (1993) 4.13

A Monte Carlo method for combined segregation and linkage analysis. Am J Hum Genet (1992) 3.98

Allowing for missing parents in genetic studies of case-parent triads. Am J Hum Genet (1999) 3.78

A multivariate family-based association test using generalized estimating equations: FBAT-GEE. Biostatistics (2003) 3.52

Multipoint oligogenic linkage analysis of quantitative traits. Genet Epidemiol (1997) 3.38

Genome scanning for linkage: an overview. Am J Hum Genet (1996) 3.11

Description of the data from the Collaborative Study on the Genetics of Alcoholism (COGA) and single-nucleotide polymorphism genotyping for Genetic Analysis Workshop 14. BMC Genet (2005) 3.04

Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. Proc Natl Acad Sci U S A (2006) 3.04

Power and design considerations for a general class of family-based association tests: quantitative traits. Am J Hum Genet (2002) 2.96

Family-based tests of association and linkage that use unaffected sibs, covariates, and interactions. Am J Hum Genet (2000) 2.59

Power calculations for a general class of family-based association tests: dichotomous traits. Am J Hum Genet (2002) 2.55

A forest-based approach to identifying gene and gene gene interactions. Proc Natl Acad Sci U S A (2007) 2.36

The inheritance of Gilles de la Tourette's syndrome and associated behaviors. Evidence for autosomal dominant transmission. N Engl J Med (1986) 2.30

Psychiatric disorders in foster home reared children of schizophrenic mothers. Br J Psychiatry (1966) 2.03

The collaborative study on the genetics of alcoholism: an update. Alcohol Res Health (2002) 1.97

Direct power comparisons between simple LOD scores and NPL scores for linkage analysis in complex diseases. Am J Hum Genet (1999) 1.87

Biological and genetic characteristics of HIV infections in Cameroon reveals dual group M and O infections and a correlation between SI-inducing phenotype of the predominant CRF02_AG variant and disease stage. Virology (2003) 1.76

Using dimensional models of externalizing psychopathology to aid in gene identification. Arch Gen Psychiatry (2008) 1.73

Interrelationship of genetic and environmental influences on conduct disorder and alcohol and marijuana dependence symptoms. Am J Med Genet (1999) 1.72

New insights into the genetics of addiction. Nat Rev Genet (2009) 1.70

Why Do We Test Multiple Traits in Genetic Association Studies? J Korean Stat Soc (2009) 1.62

An Association Test for Multiple Traits Based on the Generalized Kendall's Tau. J Am Stat Assoc (2010) 1.41

Mapping quantitative trait loci for ordered categorical traits in four-way crosses. Heredity (Edinb) (1998) 1.40

Detection of genes for ordinal traits in nuclear families and a unified approach for association studies. Genetics (2005) 1.38

Interaction between genetic vulnerability and family environment: the Finnish adoptive family study of schizophrenia. Acta Psychiatr Scand (1991) 1.18

Using exact P values to compare the power between the reconstruction-combined transmission/disequilibrium test and the sib transmission/disequilibrium test. Am J Hum Genet (1999) 1.17

Lack of association between SLITRK1var321 and Tourette syndrome in a large family-based sample. Neurology (2008) 1.14

A genome-wide linkage and association study using COGA data. BMC Genet (2005) 1.14

A unified framework for transmission-disequilibrium test analysis of discrete and continuous traits. Genet Epidemiol (2002) 1.12

Gene-environment interaction effects on behavioral variation and risk of complex disorders: the example of alcoholism and other psychiatric disorders. Twin Res (2002) 1.10

Family-based association tests for ordinal traits adjusting for covariates. Genet Epidemiol (2006) 1.10

Linkage analysis of ordinal traits for pedigree data. Proc Natl Acad Sci U S A (2004) 1.02

Segregation analysis of schizophrenia under a mixed genetic model. Hum Hered (1980) 0.99

The nuclear transcription factor PKNOX2 is a candidate gene for substance dependence in European-origin women. PLoS One (2011) 0.97

5. Genetics of hypersensitivity. J Allergy Clin Immunol (2003) 0.95

A frailty model of segregation analysis: understanding the familial transmission of alcoholism. Biometrics (2000) 0.92

Modeling multivariate survival data by a semiparametric random effects proportional odds model. Biometrics (2002) 0.91

LOT: a tool for linkage analysis of ordinal traits for pedigree data. Bioinformatics (2008) 0.78

A multivariate model for ordinal trait analysis. Heredity (Edinb) (2006) 0.77

Articles by these authors

A tree-based method for modeling a multivariate ordinal response. Stat Interface (2008) 1.01