Published in Am J Hum Genet on November 21, 2002
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Genome-wide association and follow-up replication studies identified ADAMTS18 and TGFBR3 as bone mass candidate genes in different ethnic groups. Am J Hum Genet (2009) 2.14
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Single-nucleotide polymorphism rs498055 on chromosome 10q24 is not associated with Alzheimer disease in two independent family samples. Am J Hum Genet (2006) 1.06
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Development of a Pharmacogenetic Predictive Test in asthma: proof of concept. Pharmacogenet Genomics (2010) 0.79
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Neuregulin 1 and age of onset in the major psychoses. J Neural Transm (Vienna) (2009) 0.77
Gene-environment interaction between the oxytocin receptor (OXTR) gene and parenting behaviour on children's theory of mind. Soc Cogn Affect Neurosci (2015) 0.77
MYBPH acts as modifier of cardiac hypertrophy in hypertrophic cardiomyopathy (HCM) patients. Hum Genet (2016) 0.75
Testing for genetic association in the presence of linkage and gene-covariate interactions. Biom J (2010) 0.75
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Removing the sampling restrictions from family-based tests of association for a quantitative-trait locus. Am J Hum Genet (2000) 2.62
Family-based tests of association and linkage that use unaffected sibs, covariates, and interactions. Am J Hum Genet (2000) 2.59
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Power comparisons of the transmission/disequilibrium test and sib-transmission/disequilibrium-test statistics. Am J Hum Genet (1999) 1.13
Testing quantitative traits for association and linkage in the presence or absence of parental data. Hum Hered (2001) 0.93
A common genetic variant is associated with adult and childhood obesity. Science (2006) 14.95
Family-based tests for associating haplotypes with general phenotype data: application to asthma genetics. Genet Epidemiol (2004) 5.57
Genomic screening and replication using the same data set in family-based association testing. Nat Genet (2005) 5.44
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PBAT: tools for family-based association studies. Am J Hum Genet (2004) 4.68
A multivariate family-based association test using generalized estimating equations: FBAT-GEE. Biostatistics (2003) 3.52
Variants in FAM13A are associated with chronic obstructive pulmonary disease. Nat Genet (2010) 3.44
Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. Am J Hum Genet (2005) 3.24
A new testing strategy to identify rare variants with either risk or protective effect on disease. PLoS Genet (2011) 3.13
On a general class of conditional tests for family-based association studies in genetics: the asymptotic distribution, the conditional power, and optimality considerations. Genet Epidemiol (2002) 2.76
Power calculations for a general class of family-based association tests: dichotomous traits. Am J Hum Genet (2002) 2.55
Genomewide weighted hypothesis testing in family-based association studies, with an application to a 100K scan. Am J Hum Genet (2007) 2.45
The transforming growth factor-beta1 (TGFB1) gene is associated with chronic obstructive pulmonary disease (COPD). Hum Mol Genet (2004) 2.19
Using the noninformative families in family-based association tests: a powerful new testing strategy. Am J Hum Genet (2003) 2.18
A family-based association test for repeatedly measured quantitative traits adjusting for unknown environmental and/or polygenic effects. Stat Appl Genet Mol Biol (2004) 2.15
Early-onset chronic obstructive pulmonary disease is associated with female sex, maternal factors, and African American race in the COPDGene Study. Am J Respir Crit Care Med (2011) 2.06
Cigarette smoking in relation to depression: historical trends from the Stirling County Study. Am J Psychiatry (2003) 1.90
Gender differences in COPD: are women more susceptible to smoking effects than men? Thorax (2010) 1.82
Positively selected G6PD-Mahidol mutation reduces Plasmodium vivax density in Southeast Asians. Science (2009) 1.77
Heritability of chronic obstructive pulmonary disease and related phenotypes in smokers. Am J Respir Crit Care Med (2013) 1.67
Racial differences in quality of life in patients with COPD. Chest (2011) 1.64
Binge-eating disorder as a distinct familial phenotype in obese individuals. Arch Gen Psychiatry (2006) 1.58
Reduced Bone Density and Vertebral Fractures in Smokers. Men and COPD Patients at Increased Risk. Ann Am Thorac Soc (2015) 1.54
Family, peer, and media predictors of becoming eating disordered. Arch Pediatr Adolesc Med (2008) 1.53
Co-occurrence of binge eating disorder with psychiatric and medical disorders. J Clin Psychiatry (2008) 1.50
Cluster analysis in the COPDGene study identifies subtypes of smokers with distinct patterns of airway disease and emphysema. Thorax (2014) 1.48
On the analysis of copy-number variations in genome-wide association studies: a translation of the family-based association test. Genet Epidemiol (2008) 1.47
Gene-environment interaction tests for dichotomous traits in trios and sibships. Genet Epidemiol (2009) 1.43
Prospective association of common eating disorders and adverse outcomes. Pediatrics (2012) 1.41
Family-based association tests for survival and times-to-onset analysis. Stat Med (2004) 1.35
On the optimal design of genetic variant discovery studies. Stat Appl Genet Mol Biol (2010) 1.35
A new multimarker test for family-based association studies. Genet Epidemiol (2007) 1.34
Family-based association analysis of beta2-adrenergic receptor polymorphisms in the childhood asthma management program. J Allergy Clin Immunol (2003) 1.34
Family study of affective spectrum disorder. Arch Gen Psychiatry (2003) 1.30
Xenobiotic metabolizing enzyme gene polymorphisms predict response to lung volume reduction surgery. Respir Res (2007) 1.27
Variable DNA methylation is associated with chronic obstructive pulmonary disease and lung function. Am J Respir Crit Care Med (2011) 1.26
Familiality and heritability of binge eating disorder: results of a case-control family study and a twin study. Int J Eat Disord (2008) 1.17
The corticotropin-releasing hormone gene and behavioral inhibition in children at risk for panic disorder. Biol Psychiatry (2005) 1.15
Predictors of survival in severe, early onset COPD. Chest (2004) 1.09
Association of a genetic marker at the corticotropin-releasing hormone locus with behavioral inhibition. Biol Psychiatry (2003) 1.07
Epidemiology, genetics, and subtyping of preserved ratio impaired spirometry (PRISm) in COPDGene. Respir Res (2014) 1.06
Polymorphisms in surfactant protein-D are associated with chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol (2010) 1.04
Variance calculations for identity-by-descent estimation. Am J Hum Genet (2006) 1.02
Genetic association of Alzheimer's disease with multiple polymorphisms in alpha-2-macroglobulin. Hum Mol Genet (2003) 1.01
fgui: A Method for Automatically Creating Graphical User Interfaces for Command-Line R Packages. J Stat Softw (2009) 0.96
Genome-wide association study on overall survival of advanced non-small cell lung cancer patients treated with carboplatin and paclitaxel. J Thorac Oncol (2011) 0.96
Racial differences in CT phenotypes in COPD. COPD (2013) 0.95
Genetic polymorphisms of estrogen metabolizing enzyme and breast cancer risk in Thai women. Int J Cancer (2009) 0.95
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Opportunities and challenges in the genetics of COPD 2010: an International COPD Genetics Conference report. COPD (2011) 0.93
Non-emphysematous chronic obstructive pulmonary disease is associated with diabetes mellitus. BMC Pulm Med (2014) 0.93
National Emphysema Treatment Trial state of the art: genetics of emphysema. Proc Am Thorac Soc (2008) 0.92
Regression analysis of multiple-source longitudinal outcomes: a "Stirling County" depression study. Am J Epidemiol (2002) 0.91
Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene. PLoS One (2013) 0.91
Genome-wide association analysis of body mass in chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol (2010) 0.90
Tests for compositional epistasis under single interaction-parameter models. Ann Hum Genet (2010) 0.90
Genetic linkage and association analysis of COPD-related traits on chromosome 8p. COPD (2006) 0.89
Multistudy fine mapping of chromosome 2q identifies XRCC5 as a chronic obstructive pulmonary disease susceptibility gene. Am J Respir Crit Care Med (2010) 0.89
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Clinical predictors of frequent exacerbations in subjects with severe chronic obstructive pulmonary disease (COPD). Respir Med (2010) 0.89
Epigenetic Signatures of Cigarette Smoking. Circ Cardiovasc Genet (2016) 0.88
Genetic association analysis of COPD candidate genes with bronchodilator responsiveness. Respir Med (2008) 0.88
Mortality associated with depression: a forty-year perspective from the Stirling County Study. Soc Psychiatry Psychiatr Epidemiol (2008) 0.88
A structural approach to the familial coaggregation of disorders. Epidemiology (2008) 0.88
Systemic steroid exposure is associated with differential methylation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2012) 0.87
On the frequency of copy number variants. Bioinformatics (2008) 0.86
Estimating disease prevalence using relatives of case and control probands. Biometrics (2009) 0.85
Penalized solutions to functional regression problems. Comput Stat Data Anal (2007) 0.84
Linkage disequilibrium mapping of the chromosome 6q21-22.31 bipolar I disorder susceptibility locus. Am J Med Genet B Neuropsychiatr Genet (2010) 0.83
Gene-environment interaction tests for family studies with quantitative phenotypes: A review and extension to longitudinal measures. Hum Genomics (2010) 0.83
Incorporating missingness for estimation of marginal regression models with multiple source predictors. Stat Med (2007) 0.83
Ozone exposure, vitamin C intake, and genetic susceptibility of asthmatic children in Mexico City: a cohort study. Respir Res (2013) 0.82
Integrating Multiple Correlated Phenotypes for Genetic Association Analysis by Maximizing Heritability. Hum Hered (2015) 0.82
Fetal lung and placental methylation is associated with in utero nicotine exposure. Epigenetics (2014) 0.82
Identifying rare variants using a Bayesian regression approach. BMC Proc (2011) 0.82
Impact of population stratification on family-based association tests with longitudinal measurements. Stat Appl Genet Mol Biol (2009) 0.81
Incidence of major depression: prediction from subthreshold categories in the Stirling County Study. J Affect Disord (2002) 0.80
Genomic screening in family-based association testing. BMC Genet (2005) 0.80
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On the parsing of statistical information in family-based association testing. Nat Genet (2007) 0.79
The Yin and Yang of COPD: sex/gender differences in the National Emphysema Treatment Trial. Am J Respir Crit Care Med (2007) 0.78
A novel method for detecting association between DNA methylation and diseases using spatial information. Genet Epidemiol (2014) 0.77
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Non-linear hierarchical models for monitoring compliance. Stat Med (2002) 0.77
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Combining disease models to test for gene-environment interaction in nuclear families. Biometrics (2011) 0.76
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Comparison of linkage and association strategies for quantitative traits using the COGA dataset. BMC Genet (2005) 0.75
Parsing the effects of individual SNPs in candidate genes with family data. Hum Hered (2009) 0.75
Optimism and Cause-Specific Mortality: A Prospective Cohort Study. Am J Epidemiol (2016) 0.75
Estimating the effect of a predictor measured by two informants on a continuous outcome: a comparison of methods. Epidemiology (2011) 0.75
Differentiating population stratification from genotyping error using family data. Ann Hum Genet (2011) 0.75
FBAT-SNP-PC: an approach for multiple markers and single trait in family-based association tests. Hum Hered (2008) 0.75