Published in Epigenetics on October 01, 2011
DNA methylation as clinically useful biomarkers-light at the end of the tunnel. Pharmaceuticals (Basel) (2012) 0.99
Epipolymorphisms within lipoprotein genes contribute independently to plasma lipid levels in familial hypercholesterolemia. Epigenetics (2014) 0.92
Heart rate variability and DNA methylation levels are altered after short-term metal fume exposure among occupational welders: a repeated-measures panel study. BMC Public Health (2014) 0.87
Associations between serum perfluoroalkyl acids and LINE-1 DNA methylation. Environ Int (2013) 0.86
Type 2 diabetes mellitus in relation to global LINE-1 DNA methylation in peripheral blood: a cohort study. Epigenetics (2014) 0.85
LINE-1 methylation in visceral adipose tissue of severely obese individuals is associated with metabolic syndrome status and related phenotypes. Clin Epigenetics (2012) 0.83
Dietary intake, plasma homocysteine, and repetitive element DNA methylation in the Multi-Ethnic Study of Atherosclerosis (MESA). Nutr Metab Cardiovasc Dis (2013) 0.83
A lower degree of PBMC L1 methylation is associated with excess body weight and higher HOMA-IR in the presence of lower concentrations of plasma folate. PLoS One (2013) 0.83
A prospective study of LINE-1DNA methylation and development of adiposity in school-age children. PLoS One (2013) 0.82
Gene-specific DNA methylation profiles and LINE-1 hypomethylation are associated with myocardial infarction risk. Clin Epigenetics (2015) 0.79
Clinical applications of epigenetics in cardiovascular disease: the long road ahead. Transl Res (2014) 0.78
No effect of weight loss on LINE-1 methylation levels in peripheral blood leukocytes from postmenopausal overweight women. Obesity (Silver Spring) (2014) 0.76
LINE-1 hypomethylation is associated with the risk of coronary heart disease in Chinese population. Arq Bras Cardiol (2014) 0.76
Epigenetics of Lipid Phenotypes. Curr Cardiovasc Risk Rep (2016) 0.76
Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice. Sci Rep (2016) 0.75
Epigenetics, and human biology and health responses to modernization in the Samoan archipelago. Coll Antropol (2012) 0.75
Insulin-like growth factors and their potential role in cardiac epigenetics. J Cell Mol Med (2016) 0.75
A lower degree of PBMC L1 methylation in women with lower folate status may explain the MTHFR C677T polymorphism associated higher risk of CIN in the US post folic acid fortification era. PLoS One (2014) 0.75
Identification of differentially methylated BRCA1 and CRISP2 DNA regions as blood surrogate markers for cardiovascular disease. Sci Rep (2017) 0.75
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DNA methylation patterns and epigenetic memory. Genes Dev (2002) 33.83
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DNA methylation profiling of human chromosomes 6, 20 and 22. Nat Genet (2006) 18.08
Atherosclerosis. Nature (2000) 15.95
Phenotypic plasticity and the epigenetics of human disease. Nature (2007) 10.37
The impact of retrotransposons on human genome evolution. Nat Rev Genet (2009) 8.08
Changes in DNA methylation patterns in subjects exposed to low-dose benzene. Cancer Res (2007) 4.89
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LINE-1 activity in facultative heterochromatin formation during X chromosome inactivation. Cell (2010) 3.70
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Increase in plasma homocysteine associated with parallel increases in plasma S-adenosylhomocysteine and lymphocyte DNA hypomethylation. J Biol Chem (2000) 2.60
DNA methylation in white blood cells: association with risk factors in epidemiologic studies. Epigenetics (2011) 2.51
Folate treatment and unbalanced methylation and changes of allelic expression induced by hyperhomocysteinaemia in patients with uraemia. Lancet (2003) 2.39
Gender specific differences in levels of DNA methylation at selected loci from human total blood: a tendency toward higher methylation levels in males. Hum Genet (2007) 2.36
Predictors of global methylation levels in blood DNA of healthy subjects: a combined analysis. Int J Epidemiol (2010) 2.34
Global DNA hypomethylation is associated with high serum-persistent organic pollutants in Greenlandic Inuit. Environ Health Perspect (2008) 2.29
Implications of LINE1 methylation for bladder cancer risk in women. Clin Cancer Res (2010) 2.10
Ischemic heart disease and stroke in relation to blood DNA methylation. Epidemiology (2010) 2.10
DNA methylation as a biomarker for cardiovascular disease risk. PLoS One (2010) 2.04
Impact of inflammation on epigenetic DNA methylation - a novel risk factor for cardiovascular disease? J Intern Med (2007) 1.97
DNA methylation polymorphisms precede any histological sign of atherosclerosis in mice lacking apolipoprotein E. J Biol Chem (2004) 1.82
Epigenetics and atherosclerosis. Biochim Biophys Acta (2009) 1.72
LINE-1 hypomethylation is associated with bladder cancer risk among nonsmoking Chinese. Int J Cancer (2011) 1.56
Detection of altered global DNA methylation in coronary artery disease patients. DNA Cell Biol (2008) 1.50
Lipoprotein subfractions and cardiovascular disease risk. Curr Opin Lipidol (2010) 1.49
Repetitive element DNA methylation and circulating endothelial and inflammation markers in the VA normative aging study. Epigenetics (2010) 1.44
Correlation of global and gene-specific DNA methylation in maternal-infant pairs. PLoS One (2010) 1.40
DNA hypomethylation and methyltransferase expression in atherosclerotic lesions. Vasc Med (2002) 1.40
Dietary patterns are associated with metabolic syndrome in adult Samoans. J Nutr (2009) 1.32
DNA methylation, smooth muscle cells, and atherogenesis. Arterioscler Thromb Vasc Biol (2003) 1.29
Genome-wide scan for adiposity-related phenotypes in adults from American Samoa. Int J Obes (Lond) (2007) 1.16
Diabetes: a candidate disease for efficient DNA methylation profiling. J Nutr (2002) 1.14
A genome-wide linkage scan identifies multiple chromosomal regions influencing serum lipid levels in the population on the Samoan islands. J Lipid Res (2008) 1.11
Homocysteine-mediated expression of SAHH, DNMTs, MBD2, and DNA hypomethylation potential pathogenic mechanism in VSMCs. DNA Cell Biol (2007) 1.10
Effects of insulin and glucose on cellular metabolic fluxes in homocysteine transsulfuration, remethylation, S-adenosylmethionine synthesis, and global deoxyribonucleic acid methylation. J Clin Endocrinol Metab (2008) 1.06
Global DNA methylation levels in girls with and without a family history of breast cancer. Epigenetics (2011) 1.06
A whole genome linkage scan identifies multiple chromosomal regions influencing adiposity-related traits among Samoans. Ann Hum Genet (2008) 0.98
Susceptibility loci for adiposity phenotypes on 8p, 9p, and 16q in American Samoa and Samoa. Obesity (Silver Spring) (2008) 0.97
Distribution of genome-wide linkage disequilibrium based on microsatellite loci in the Samoan population. Hum Genomics (2004) 0.96
Hyper-homocysteinemia: a novel risk factor or a powerful marker for cardiovascular diseases? Pathogenetic and therapeutical uncertainties. J Thromb Thrombolysis (2011) 0.94
Apolipoprotein E-deficient mouse model of human atherosclerosis. Toxicol Pathol (1997) 0.83
DNA methylation arrays as surrogate measures of cell mixture distribution. BMC Bioinformatics (2012) 9.31
Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context. PLoS Genet (2009) 7.07
DNA sequencing of maternal plasma to detect Down syndrome: an international clinical validation study. Genet Med (2011) 4.98
Global DNA methylation level in whole blood as a biomarker in head and neck squamous cell carcinoma. Cancer Epidemiol Biomarkers Prev (2007) 4.01
Health Effects of Overweight and Obesity in 195 Countries over 25 Years. N Engl J Med (2017) 3.90
Model-based clustering of DNA methylation array data: a recursive-partitioning algorithm for high-dimensional data arising as a mixture of beta distributions. BMC Bioinformatics (2008) 3.89
Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium. J Natl Cancer Inst (2010) 3.18
DNA sequencing of maternal plasma reliably identifies trisomy 18 and trisomy 13 as well as Down syndrome: an international collaborative study. Genet Med (2012) 3.18
MicroRNA responses to cellular stress. Cancer Res (2006) 3.13
Fundamental differences in cell cycle deregulation in human papillomavirus-positive and human papillomavirus-negative head/neck and cervical cancers. Cancer Res (2007) 2.93
DNA methylation, isocitrate dehydrogenase mutation, and survival in glioma. J Natl Cancer Inst (2010) 2.87
World Heart Federation criteria for echocardiographic diagnosis of rheumatic heart disease--an evidence-based guideline. Nat Rev Cardiol (2012) 2.75
Lack of association of alcohol and tobacco with HPV16-associated head and neck cancer. J Natl Cancer Inst (2007) 2.68
Reference-free cell mixture adjustments in analysis of DNA methylation data. Bioinformatics (2014) 2.61
Human schistosomiasis and anemia: the relationship and potential mechanisms. Trends Parasitol (2005) 2.58
Functional significance of low-intensity polyparasite helminth infections in anemia. J Infect Dis (2005) 2.56
A case-control study of smoking and bladder cancer risk: emergent patterns over time. J Natl Cancer Inst (2009) 2.40
A let-7 microRNA-binding site polymorphism in the KRAS 3' UTR is associated with reduced survival in oral cancers. Carcinogenesis (2009) 2.28
Nutritional status and serum cytokine profiles in children, adolescents, and young adults with Schistosoma japonicum-associated hepatic fibrosis, in Leyte, Philippines. J Infect Dis (2005) 2.28
Human papillomavirus type 16 and squamous cell carcinoma of the head and neck. Clin Cancer Res (2002) 2.20
Recommendations for the design and analysis of epigenome-wide association studies. Nat Methods (2013) 2.19
MicroRNA expression ratio is predictive of head and neck squamous cell carcinoma. Clin Cancer Res (2009) 2.13
Implications of LINE1 methylation for bladder cancer risk in women. Clin Cancer Res (2010) 2.10
Concordance of multiple analytical approaches demonstrates a complex relationship between DNA repair gene SNPs, smoking and bladder cancer susceptibility. Carcinogenesis (2005) 2.08
Nightshift work and genome-wide DNA methylation. Chronobiol Int (2014) 2.01
Epigenetic profiling reveals etiologically distinct patterns of DNA methylation in head and neck squamous cell carcinoma. Carcinogenesis (2009) 1.94
DNA methylation array analysis identifies profiles of blood-derived DNA methylation associated with bladder cancer. J Clin Oncol (2011) 1.92
Inactivation of the Fanconi anemia/BRCA pathway in lung and oral cancers: implications for treatment and survival. Oncogene (2004) 1.82
Toxicity testing in the 21st century: a vision and a strategy. J Toxicol Environ Health B Crit Rev (2010) 1.81
Blood-based profiles of DNA methylation predict the underlying distribution of cell types: a validation analysis. Epigenetics (2013) 1.79
Human papillomavirus 16 and head and neck squamous cell carcinoma. Int J Cancer (2007) 1.78
Epigenetics in the placenta. Am J Reprod Immunol (2009) 1.77
Peripheral blood immune cell methylation profiles are associated with nonhematopoietic cancers. Cancer Epidemiol Biomarkers Prev (2012) 1.76
Biomarkers of HPV in head and neck squamous cell carcinoma. Cancer Res (2012) 1.76
Breast cancer DNA methylation profiles are associated with tumor size and alcohol and folate intake. PLoS Genet (2010) 1.74
Epigenetic profiles distinguish pleural mesothelioma from normal pleura and predict lung asbestos burden and clinical outcome. Cancer Res (2009) 1.73
Sexual behaviours and the risk of head and neck cancers: a pooled analysis in the International Head and Neck Cancer Epidemiology (INHANCE) consortium. Int J Epidemiol (2009) 1.70
A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium. PLoS Genet (2011) 1.68
PTEN expression in non-small-cell lung cancer: evaluating its relation to tumor characteristics, allelic loss, and epigenetic alteration. Hum Pathol (2005) 1.67
Differential DNA methylation in umbilical cord blood of infants exposed to low levels of arsenic in utero. Environ Health Perspect (2013) 1.66
The ADH1C polymorphism modifies the risk of squamous cell carcinoma of the head and neck associated with alcohol and tobacco use. Cancer Epidemiol Biomarkers Prev (2005) 1.64
Semi-supervised recursively partitioned mixture models for identifying cancer subtypes. Bioinformatics (2010) 1.63
A computationally efficient hypothesis testing method for epistasis analysis using multifactor dimensionality reduction. Genet Epidemiol (2009) 1.61
Decision-model estimation of the age-specific disability weight for schistosomiasis japonica: a systematic review of the literature. PLoS Negl Trop Dis (2008) 1.59
LINE-1 hypomethylation is associated with bladder cancer risk among nonsmoking Chinese. Int J Cancer (2011) 1.56
High-risk HPV types and head and neck cancer. Int J Cancer (2014) 1.56
Carcinogen exposure and gene promoter hypermethylation in bladder cancer. Carcinogenesis (2005) 1.55
Pubertal development predicts resistance to infection and reinfection with Schistosoma japonicum. Clin Infect Dis (2006) 1.54
Epigenetic inactivation of the SFRP genes is associated with drinking, smoking and HPV in head and neck squamous cell carcinoma. Int J Cancer (2006) 1.53
Schistosomiasis japonica, anemia, and iron status in children, adolescents, and young adults in Leyte, Philippines 1. Am J Clin Nutr (2006) 1.53
Serum IgE, tumor epidermal growth factor receptor expression, and inherited polymorphisms associated with glioma survival. Cancer Res (2006) 1.52
Patterns of gene promoter methylation in squamous cell cancer of the head and neck. Oncogene (2002) 1.49
The influence of socioeconomic factors on cardiovascular disease risk factors in the context of economic development in the Samoan archipelago. Soc Sci Med (2006) 1.49
The synergistic effect of concomitant schistosomiasis, hookworm, and trichuris infections on children's anemia burden. PLoS Negl Trop Dis (2008) 1.49
Birthweight is associated with DNA promoter methylation of the glucocorticoid receptor in human placenta. Epigenetics (2011) 1.47
A population-based study of the Arg399Gln polymorphism in X-ray repair cross- complementing group 1 (XRCC1) and risk of pancreatic adenocarcinoma. Cancer Res (2002) 1.45
Molecular features of adult glioma associated with patient race/ethnicity, age, and a polymorphism in O6-methylguanine-DNA-methyltransferase. Cancer Epidemiol Biomarkers Prev (2005) 1.44
Mature microRNA sequence polymorphism in MIR196A2 is associated with risk and prognosis of head and neck cancer. Clin Cancer Res (2010) 1.44
Infant growth restriction is associated with distinct patterns of DNA methylation in human placentas. Epigenetics (2011) 1.44
Bladder cancer SNP panel predicts susceptibility and survival. Hum Genet (2009) 1.43
In utero exposures, infant growth, and DNA methylation of repetitive elements and developmentally related genes in human placenta. Environ Health Perspect (2011) 1.43
Comparison of serum markers in first-trimester down syndrome screening. Obstet Gynecol (2006) 1.43
Polymorphisms in DNA repair genes, smoking, and bladder cancer risk: findings from the international consortium of bladder cancer. Cancer Res (2009) 1.43
Epigenetic inactivation of SFRP genes and TP53 alteration act jointly as markers of invasive bladder cancer. Cancer Res (2005) 1.40
Promoter hypermethylation is associated with current smoking, age, gender and survival in bladder cancer. Carcinogenesis (2007) 1.40
Schistosoma japonicum reinfection after praziquantel treatment causes anemia associated with inflammation. Infect Immun (2006) 1.37
Genetic and epigenetic variation of the glucocorticoid receptor (NR3C1) in placenta and infant neurobehavior. Dev Psychobiol (2012) 1.36
Peripheral blood DNA methylation profiles are indicative of head and neck squamous cell carcinoma: an epigenome-wide association study. Epigenetics (2012) 1.35
Relationship between Schistosoma japonicum and nutritional status among children and young adults in Leyte, the Philippines. Am J Trop Med Hyg (2005) 1.33
A population-based, case-control study of polymorphisms in carcinogen-metabolizing genes, smoking, and pancreatic adenocarcinoma risk. J Natl Cancer Inst (2002) 1.33
Bisphenol A exposure leads to specific microRNA alterations in placental cells. Reprod Toxicol (2010) 1.33
Survival following the diagnosis of noninvasive bladder cancer: WHO/International Society of Urological Pathology versus WHO classification systems. J Urol (2007) 1.33
Detecting pathway-based gene-gene and gene-environment interactions in pancreatic cancer. Cancer Epidemiol Biomarkers Prev (2008) 1.33
Microsatellite instability at tetranucleotide repeats in skin and bladder cancer. Oncogene (2002) 1.33
Enabling personal genomics with an explicit test of epistasis. Pac Symp Biocomput (2010) 1.33
Quantitative reconstruction of leukocyte subsets using DNA methylation. Genome Biol (2014) 1.32