Published in J Immunol on October 03, 2011
Cytometry: today's technology and tomorrow's horizons. Methods (2012) 1.38
An intestinal commensal symbiosis factor controls neuroinflammation via TLR2-mediated CD39 signalling. Nat Commun (2014) 1.11
Adoptive transfer of human gingiva-derived mesenchymal stem cells ameliorates collagen-induced arthritis via suppression of Th1 and Th17 cells and enhancement of regulatory T cell differentiation. Arthritis Rheum (2013) 1.05
Oral Escherichia coli colonization factor antigen I fimbriae ameliorate arthritis via IL-35, not IL-27. J Immunol (2013) 0.83
Antigen-specific gene therapy after immunisation reduces the severity of collagen-induced arthritis. Clin Dev Immunol (2013) 0.82
IL-4/CCL22/CCR4 axis controls regulatory T-cell migration that suppresses inflammatory bone loss in murine experimental periodontitis. J Bone Miner Res (2015) 0.82
Interferon alpha inhibits antigen-specific production of proinflammatory cytokines and enhances antigen-specific transforming growth factor beta production in antigen-induced arthritis. Arthritis Res Ther (2013) 0.81
Milk-based nutraceutical for treating autoimmune arthritis via the stimulation of IL-10- and TGF-β-producing CD39+ regulatory T cells. PLoS One (2015) 0.78
Bystander-mediated stimulation of proteolipid protein-specific regulatory T (Treg) cells confers protection against experimental autoimmune encephalomyelitis (EAE) via TGF-β. J Neuroimmunol (2012) 0.78
The influence of gut-derived CD39 regulatory T cells in CNS demyelinating disease. Transl Res (2016) 0.77
Regulatory T-cell vaccination independent of auto-antigen. Exp Mol Med (2014) 0.77
Human seminal plasma fosters CD4(+) regulatory T-cell phenotype and transforming growth factor-β1 expression. Am J Reprod Immunol (2012) 0.77
Induction of gut regulatory CD39(+) T cells by teriflunomide protects against EAE. Neurol Neuroimmunol Neuroinflamm (2016) 0.76
Regulatory CD4+CD25+ T Cells Dampen Inflammatory Disease in Murine Mycoplasma Pneumonia and Promote IL-17 and IFN-γ Responses. PLoS One (2016) 0.75
Erosive arthritis and hepatic granuloma formation induced by peptidoglycan polysaccharide in rats is aggravated by prasugrel treatment. PLoS One (2013) 0.75
A Novel Approach to Reinstating Tolerance in Experimental Autoimmune Myasthenia Gravis Using a Targeted Fusion Protein, mCTA1-T146. Front Immunol (2017) 0.75
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol (2003) 38.57
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol (1995) 29.42
Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice. J Immunol (2003) 10.21
Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression. J Exp Med (2007) 10.00
Inducing and expanding regulatory T cell populations by foreign antigen. Nat Immunol (2005) 9.91
Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression. Blood (2007) 6.03
Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans. Nat Rev Immunol (2007) 4.55
IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells. J Immunol (2004) 3.46
T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5'-adenosine monophosphate to adenosine. J Immunol (2006) 3.40
Induction and mechanism of action of transforming growth factor-beta-secreting Th3 regulatory cells. Immunol Rev (2001) 3.31
Protective effect of transforming growth factor beta 1 on experimental autoimmune diseases in mice. Proc Natl Acad Sci U S A (1991) 3.19
Cyclic adenosine monophosphate is a key component of regulatory T cell-mediated suppression. J Exp Med (2007) 2.88
Absence of the P2X7 receptor alters leukocyte function and attenuates an inflammatory response. J Immunol (2002) 2.71
Purinergic modulation of interleukin-1 beta release from microglial cells stimulated with bacterial endotoxin. J Exp Med (1997) 2.52
FOXP3 modifies the phenotypic and functional properties of regulatory T cells. Nat Rev Immunol (2007) 2.46
CD39+Foxp3+ regulatory T Cells suppress pathogenic Th17 cells and are impaired in multiple sclerosis. J Immunol (2009) 2.30
Mechanisms maintaining peripheral tolerance. Nat Immunol (2009) 2.14
Interleukin-17 receptor deficiency results in impaired synovial expression of interleukin-1 and matrix metalloproteinases 3, 9, and 13 and prevents cartilage destruction during chronic reactivated streptococcal cell wall-induced arthritis. Arthritis Rheum (2005) 1.93
The IL-4 receptor alpha-chain-binding cytokines, IL-4 and IL-13, induce forkhead box P3-expressing CD25+CD4+ regulatory T cells from CD25-CD4+ precursors. J Immunol (2005) 1.66
Expression of CD39 by human peripheral blood CD4+ CD25+ T cells denotes a regulatory memory phenotype. Am J Transplant (2010) 1.55
IL-35 stimulation of CD39+ regulatory T cells confers protection against collagen II-induced arthritis via the production of IL-10. J Immunol (2010) 1.53
Th17 and regulatory T cells: rebalancing pro- and anti-inflammatory forces in autoimmune arthritis. Rheumatology (Oxford) (2009) 1.51
A sudden decline in active membrane-bound TGF-beta impairs both T regulatory cell function and protection against autoimmune diabetes. J Immunol (2004) 1.48
High expression of the ectonucleotidase CD39 on T cells from the inflamed site identifies two distinct populations, one regulatory and one memory T cell population. J Immunol (2010) 1.33
Regulatory T cell vaccination without autoantigen protects against experimental autoimmune encephalomyelitis. J Immunol (2007) 1.30
Collagen-induced arthritis in C57BL/6 mice is associated with a robust and sustained T-cell response to type II collagen. Arthritis Res Ther (2007) 1.29
Isolated CD39 expression on CD4+ T cells denotes both regulatory and memory populations. Am J Transplant (2009) 1.27
The molecular pathogenesis of collagen-induced arthritis in mice--a model for rheumatoid arthritis. Ageing Res Rev (2002) 1.26
The mouse model of collagen-induced arthritis. Methods Mol Med (2004) 1.26
Adenosine and prostaglandin E2 cooperate in the suppression of immune responses mediated by adaptive regulatory T cells. J Biol Chem (2010) 1.25
Human CD4+CD25low adaptive T regulatory cells suppress delayed-type hypersensitivity during transplant tolerance. J Immunol (2007) 1.23
Collagen-induced arthritis is exacerbated in IL-10-deficient mice. Arthritis Res Ther (2002) 1.20
Purinergic receptor modulation of lipopolysaccharide signaling and inducible nitric-oxide synthase expression in RAW 264.7 macrophages. J Biol Chem (1998) 1.17
Secretion of IL-2 and IFN-gamma, but not IL-4, by antigen-specific T cells requires extracellular ATP. J Immunol (2003) 1.15
cAMP/CREB-mediated transcriptional regulation of ectonucleoside triphosphate diphosphohydrolase 1 (CD39) expression. J Biol Chem (2010) 1.11
Selective ERK activation differentiates mouse and human tolerogenic dendritic cells, expands antigen-specific regulatory T cells, and suppresses experimental inflammatory arthritis. Arthritis Rheum (2011) 1.08
Foxp3+CD4+ T cell-mediated immunosuppression involves extracellular nucleotide catabolism. Trends Immunol (2008) 1.07
A live diarrheal vaccine imprints a Th2 cell bias and acts as an anti-inflammatory vaccine. J Immunol (2005) 1.06
IL-13 production by regulatory T cells protects against experimental autoimmune encephalomyelitis independently of autoantigen. J Immunol (2008) 1.04
Vaccination without autoantigen protects against collagen II-induced arthritis via immune deviation and regulatory T cells. J Immunol (2008) 1.01
The role of IL-4 in regulation of murine collagen-induced arthritis. Clin Immunol (2002) 1.00
Oral administration of type-II collagen suppresses IL-17-associated RANKL expression of CD4+ T cells in collagen-induced arthritis. Immunol Lett (2007) 0.99
Low-dose tolerance is mediated by the microfold cell ligand, reovirus protein sigma1. J Immunol (2008) 0.97
Extracellular ATP enhances mRNA levels of nitric oxide synthase and TNF-alpha in lipopolysaccharide-treated RAW 264.7 murine macrophages. Biochem Biophys Res Commun (1995) 0.96
Escherichia coli heat-labile enterotoxin B subunit prevents autoimmune arthritis through induction of regulatory CD4+ T cells. Arthritis Rheum (2002) 0.96
Critical role of M. tuberculosis for dendritic cell maturation to induce collagen-induced arthritis in H-2b background of C57BL/6 mice. Immunology (2006) 0.91
Phosphorylation of the cyclic AMP response element binding protein mediates transforming growth factor beta-induced downregulation of cyclin A in vascular smooth muscle cells. Mol Cell Biol (2007) 0.90
Susceptibility to collagen-induced arthritis is modulated by TGFbeta responsiveness of T cells. Arthritis Res Ther (2004) 0.90
IL-28 supplants requirement for T(reg) cells in protein sigma1-mediated protection against murine experimental autoimmune encephalomyelitis (EAE). PLoS One (2010) 0.85
Prevention of collagen-induced arthritis in DBA/1 mice by oral administration of AZ-9, a bacterial polysaccharide from Klebsiella oxytoca. Immunopharmacology (2000) 0.84
IL-35 stimulation of CD39+ regulatory T cells confers protection against collagen II-induced arthritis via the production of IL-10. J Immunol (2010) 1.53
Apple polyphenols require T cells to ameliorate dextran sulfate sodium-induced colitis and dampen proinflammatory cytokine expression. J Leukoc Biol (2011) 1.48
Regulatory T cell vaccination without autoantigen protects against experimental autoimmune encephalomyelitis. J Immunol (2007) 1.30
Oral vaccination with salmonella simultaneously expressing Yersinia pestis F1 and V antigens protects against bubonic and pneumonic plague. J Immunol (2007) 1.29
Deletion of znuA virulence factor attenuates Brucella abortus and confers protection against wild-type challenge. Infect Immun (2006) 1.21
Selection of protective epitopes for Brucella melitensis by DNA vaccination. Infect Immun (2005) 1.18
A live diarrheal vaccine imprints a Th2 cell bias and acts as an anti-inflammatory vaccine. J Immunol (2005) 1.06
IL-13 production by regulatory T cells protects against experimental autoimmune encephalomyelitis independently of autoantigen. J Immunol (2008) 1.04
Vaccination without autoantigen protects against collagen II-induced arthritis via immune deviation and regulatory T cells. J Immunol (2008) 1.01
Ovalbumin-protein sigma 1 M-cell targeting facilitates oral tolerance with reduction of antigen-specific CD4+ T cells. Gastroenterology (2008) 1.00
Flagella overexpression attenuates Salmonella pathogenesis. PLoS One (2012) 0.98
HEPES-stabilized encapsulation of Salmonella typhimurium. Langmuir (2007) 0.97
Low-dose tolerance is mediated by the microfold cell ligand, reovirus protein sigma1. J Immunol (2008) 0.97
M cell DNA vaccination for CTL immunity to HIV. J Immunol (2003) 0.96
Expression of Escherichia coli virulence usher protein attenuates wild-type Salmonella. Virulence (2012) 0.96
A novel neurotoxoid vaccine prevents mucosal botulism. J Immunol (2005) 0.95
Protective live oral brucellosis vaccines stimulate Th1 and th17 cell responses. Infect Immun (2011) 0.94
Enhanced immunoglobulin A response and protection against Salmonella enterica serovar typhimurium in the absence of the substance P receptor. Infect Immun (2005) 0.93
Nasal Acai polysaccharides potentiate innate immunity to protect against pulmonary Francisella tularensis and Burkholderia pseudomallei Infections. PLoS Pathog (2012) 0.93
A nasal interleukin-12 DNA vaccine coexpressing Yersinia pestis F1-V fusion protein confers protection against pneumonic plague. Infect Immun (2008) 0.92
Expression and immunogenicity of an Escherichia coli K99 fimbriae subunit antigen in soybean. Planta (2004) 0.92
Mucosal vaccine targeting improves onset of mucosal and systemic immunity to botulinum neurotoxin A. J Immunol (2006) 0.91
Murine and bovine γδ T cells enhance innate immunity against Brucella abortus infections. PLoS One (2011) 0.91
Mucosal targeting of a BoNT/A subunit vaccine adjuvanted with a mast cell activator enhances induction of BoNT/A neutralizing antibodies in rabbits. PLoS One (2011) 0.91
Interleukin-17 protects against the Francisella tularensis live vaccine strain but not against a virulent F. tularensis type A strain. Infect Immun (2013) 0.91
Active immunization using a single dose immunotherapeutic abates established EAE via IL-10 and regulatory T cells. Eur J Immunol (2010) 0.91
Serum antibodies protect against intraperitoneal challenge with enterotoxigenic Escherichia coli. J Biomed Biotechnol (2011) 0.91
Transgene vaccination using Ulex europaeus agglutinin I (UEA-1) for targeted mucosal immunization against HIV-1 envelope. Vaccine (2005) 0.90
Absence of L-selectin delays mucosal B cell responses in nonintestinal effector tissues. J Immunol (2002) 0.90
Progress in Brucella vaccine development. Front Biol (Beijing) (2013) 0.90
Antibody selection for immobilizing living bacteria. Anal Chem (2009) 0.89
Attenuated Coxiella burnetii phase II causes a febrile response in gamma interferon knockout and Toll-like receptor 2 knockout mice and protects against reinfection. Infect Immun (2007) 0.88
Efficient immobilization and patterning of live bacterial cells. Langmuir (2008) 0.88
Nasal immunization with recombinant Brucella melitensis bp26 and trigger factor with cholera toxin reduces B. melitensis colonization. Vaccine (2006) 0.88
DeltaznuADeltapurE Brucella abortus 2308 mutant as a live vaccine candidate. Vaccine (2009) 0.88
IL-28 supplants requirement for T(reg) cells in protein sigma1-mediated protection against murine experimental autoimmune encephalomyelitis (EAE). PLoS One (2010) 0.85
Mucosal lymphatic-derived gammadelta T cells respond early to experimental Salmonella enterocolitis by increasing expression of IL-2R alpha. Cell Immunol (2007) 0.85
Bacteria survive multiple puncturings of their cell walls. Langmuir (2009) 0.84
Tolerogen-induced interferon-producing killer dendritic cells (IKDCs) protect against EAE. J Autoimmun (2011) 0.83
Oral Escherichia coli colonization factor antigen I fimbriae ameliorate arthritis via IL-35, not IL-27. J Immunol (2013) 0.83
Mucosal addressin expression and binding-interactions with naive lymphocytes vary among the cranial, oral, and nasal-associated lymphoid tissues. Eur J Immunol (2002) 0.83
IFN-γ-deficient mice develop IL-1-dependent cutaneous and musculoskeletal inflammation during experimental brucellosis. J Leukoc Biol (2012) 0.83
The absence of lymphoid CD8+ dendritic cell maturation in L-selectin-/- respiratory compartment attenuates antiviral immunity. J Immunol (2008) 0.82
Development of a transient CD4(+)CD8(+) T cell subset in the cervical lymph nodes following intratracheal instillation with an adenovirus vector. Cell Immunol (2002) 0.81
Vulnerabilities in Yersinia pestis caf operon are unveiled by a Salmonella vector. PLoS One (2012) 0.81
Mucosal vaccine development for botulinum intoxication. Expert Rev Vaccines (2007) 0.80
Sublingual immunization with adenovirus F protein-based vaccines stimulates protective immunity against botulinum neurotoxin A intoxication. Int Immunol (2011) 0.80
Partially assembled K99 fimbriae are required for protection. Infect Immun (2005) 0.80
DNA vaccination of bison to brucellar antigens elicits elevated antibody and IFN-γ responses. J Wildl Dis (2011) 0.80
An IL-12 DNA vaccine co-expressing Yersinia pestis antigens protects against pneumonic plague. Vaccine (2008) 0.80
A parenteral DNA vaccine protects against pneumonic plague. Vaccine (2010) 0.79
Immunomodulatory activity of polysaccharides isolated from Clerodendrum splendens: beneficial effects in experimental autoimmune encephalomyelitis. BMC Complement Altern Med (2013) 0.79
Bystander-mediated stimulation of proteolipid protein-specific regulatory T (Treg) cells confers protection against experimental autoimmune encephalomyelitis (EAE) via TGF-β. J Neuroimmunol (2012) 0.78
18β-glycyrrhetinic acid delivered orally induces isolated lymphoid follicle maturation at the intestinal mucosa and attenuates rotavirus shedding. PLoS One (2012) 0.78
A polymer/oil based nanovaccine as a single-dose immunization approach. PLoS One (2013) 0.77
Segregation of mechanisms for cytotoxic T lymphocyte killing between lungs and regional lymph nodes subsequent to intratracheal delivery of adenovirus 2 vector. Viral Immunol (2003) 0.76
Loss of sialic acid binding domain redirects protein σ1 to enhance M cell-directed vaccination. PLoS One (2012) 0.76
Identification and characterization of a novel class of c-Jun N-terminal kinase inhibitors. Mol Pharmacol (2012) 0.76
Adenovirus F protein as a delivery vehicle for botulinum B. BMC Immunol (2010) 0.76