PubRank

Keith Gull

Author PubWeight™ 129.75‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The genome of the African trypanosome Trypanosoma brucei. Science 2005 11.48
2 The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease. Science 2005 7.61
3 Flagellar motility is required for the viability of the bloodstream trypanosome. Nature 2006 4.71
4 The Meckel-Gruber Syndrome proteins MKS1 and meckelin interact and are required for primary cilium formation. Hum Mol Genet 2006 3.06
5 Targeting of a tetracycline-inducible expression system to the transcriptionally silent minichromosomes of Trypanosoma brucei. Mol Biochem Parasitol 2002 2.74
6 Centriole/basal body morphogenesis and migration during ciliogenesis in animal cells. J Cell Sci 2007 2.46
7 A high-order trans-membrane structural linkage is responsible for mitochondrial genome positioning and segregation by flagellar basal bodies in trypanosomes. Mol Biol Cell 2003 2.09
8 Functional genomics in Trypanosoma brucei: a collection of vectors for the expression of tagged proteins from endogenous and ectopic gene loci. Mol Biochem Parasitol 2007 1.96
9 Reconstructing the evolutionary history of the centriole from protein components. J Cell Sci 2010 1.87
10 Three-dimensional cellular architecture of the flagellar pocket and associated cytoskeleton in trypanosomes revealed by electron microscope tomography. J Cell Sci 2009 1.82
11 Dyneins across eukaryotes: a comparative genomic analysis. Traffic 2007 1.81
12 Molecular evolution of FtsZ protein sequences encoded within the genomes of archaea, bacteria, and eukaryota. J Mol Evol 2004 1.65
13 A "holistic" kinesin phylogeny reveals new kinesin families and predicts protein functions. Mol Biol Cell 2006 1.59
14 Variant surface glycoprotein RNA interference triggers a precytokinesis cell cycle arrest in African trypanosomes. Proc Natl Acad Sci U S A 2005 1.58
15 Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton. J Cell Sci 2009 1.58
16 The heart of darkness: growth and form of Trypanosoma brucei in the tsetse fly. Trends Parasitol 2009 1.54
17 Chromosome-wide analysis of gene function by RNA interference in the african trypanosome. Eukaryot Cell 2006 1.47
18 A repetitive protein essential for the flagellum attachment zone filament structure and function in Trypanosoma brucei. Protist 2007 1.44
19 Asymmetric cell division as a route to reduction in cell length and change in cell morphology in trypanosomes. Protist 2007 1.43
20 The flagella connector of Trypanosoma brucei: an unusual mobile transmembrane junction. J Cell Sci 2004 1.43
21 More than one way to build a flagellum: comparative genomics of parasitic protozoa. Curr Biol 2004 1.36
22 The DNA sequence of chromosome I of an African trypanosome: gene content, chromosome organisation, recombination and polymorphism. Nucleic Acids Res 2003 1.33
23 Trypanosome IFT mutants provide insight into the motor location for mobility of the flagella connector and flagellar membrane formation. J Cell Sci 2006 1.29
24 Cell biology of the trypanosome genome. Microbiol Mol Biol Rev 2010 1.27
25 An essential quality control mechanism at the eukaryotic basal body prior to intraflagellar transport. Traffic 2007 1.27
26 The paraflagellar rod of kinetoplastid parasites: from structure to components and function. Int J Parasitol 2009 1.25
27 The evolution of the cytoskeleton. J Cell Biol 2011 1.22
28 The Parkin co-regulated gene product, PACRG, is an evolutionarily conserved axonemal protein that functions in outer-doublet microtubule morphogenesis. J Cell Sci 2005 1.21
29 The cell cycle of Leishmania: morphogenetic events and their implications for parasite biology. Mol Microbiol 2010 1.21
30 The small chromosomes of Trypanosoma brucei involved in antigenic variation are constructed around repetitive palindromes. Genome Res 2004 1.20
31 Combining RNA interference mutants and comparative proteomics to identify protein components and dependences in a eukaryotic flagellum. J Biol Chem 2008 1.19
32 Patterns of kinesin evolution reveal a complex ancestral eukaryote with a multifunctional cytoskeleton. BMC Evol Biol 2010 1.17
33 Gamma-tubulin functions in the nucleation of a discrete subset of microtubules in the eukaryotic flagellum. Curr Biol 2003 1.17
34 Basal body movements orchestrate membrane organelle division and cell morphogenesis in Trypanosoma brucei. J Cell Sci 2010 1.14
35 The kinetoplast duplication cycle in Trypanosoma brucei is orchestrated by cytoskeleton-mediated cell morphogenesis. Mol Cell Biol 2010 1.14
36 A meckelin-filamin A interaction mediates ciliogenesis. Hum Mol Genet 2011 1.12
37 Basal body and flagellum mutants reveal a rotational constraint of the central pair microtubules in the axonemes of trypanosomes. J Cell Sci 2006 1.11
38 Diversification of function by different isoforms of conventionally shared RNA polymerase subunits. Mol Biol Cell 2007 1.11
39 The hydrocephalus inducing gene product, Hydin, positions axonemal central pair microtubules. BMC Biol 2007 1.11
40 Evolutionary relationships and protein domain architecture in an expanded calpain superfamily in kinetoplastid parasites. J Mol Evol 2005 1.10
41 Repetitive elements in genomes of parasitic protozoa. Microbiol Mol Biol Rev 2003 1.09
42 Membrane domains and flagellar pocket boundaries are influenced by the cytoskeleton in African trypanosomes. Proc Natl Acad Sci U S A 2009 1.08
43 Integration of pZJM library plasmids into unexpected locations in the Trypanosoma brucei genome. Mol Biochem Parasitol 2004 1.08
44 Cytokinesis in Trypanosoma brucei differs between bloodstream and tsetse trypomastigote forms: implications for microtubule-based morphogenesis and mutant analysis. Mol Microbiol 2013 1.04
45 Flagellar and ciliary beating in trypanosome motility. Cell Motil Cytoskeleton 2007 1.04
46 Beyond 9+0: noncanonical axoneme structures characterize sensory cilia from protists to humans. FASEB J 2010 1.04
47 Protein targeting of an unusual, evolutionarily conserved adenylate kinase to a eukaryotic flagellum. Mol Biol Cell 2004 1.03
48 Genome-wide analysis reveals extensive functional interaction between DNA replication initiation and transcription in the genome of Trypanosoma brucei. Cell Rep 2012 1.01
49 The trypanosome flagellum. J Cell Sci 2003 1.01
50 A new generation of T7 RNA polymerase-independent inducible expression plasmids for Trypanosoma brucei. PLoS One 2012 0.98
51 The limits on trypanosomatid morphological diversity. PLoS One 2013 0.98
52 Structural asymmetry and discrete nucleic acid subdomains in the Trypanosoma brucei kinetoplast. Mol Microbiol 2007 0.98
53 A SAS-6-like protein suggests that the Toxoplasma conoid complex evolved from flagellar components. Eukaryot Cell 2013 0.97
54 Histone H1 plays a role in heterochromatin formation and VSG expression site silencing in Trypanosoma brucei. PLoS Pathog 2012 0.97
55 The structural mechanics of cell division in Trypanosoma brucei. Biochem Soc Trans 2008 0.97
56 An evolutionarily conserved coiled-coil protein implicated in polycystic kidney disease is involved in basal body duplication and flagellar biogenesis in Trypanosoma brucei. Mol Cell Biol 2005 0.97
57 The frequency of gene targeting in Trypanosoma brucei is independent of target site copy number. Nucleic Acids Res 2003 0.96
58 Cryo-electron tomography and 3-D analysis of the intact flagellum in Trypanosoma brucei. J Struct Biol 2012 0.96
59 Evolution of tubulin gene arrays in Trypanosomatid parasites: genomic restructuring in Leishmania. BMC Genomics 2006 0.96
60 Evolutionary cell biology of chromosome segregation: insights from trypanosomes. Open Biol 2013 0.95
61 Cryptic paraflagellar rod in endosymbiont-containing kinetoplastid protozoa. Eukaryot Cell 2005 0.95
62 Perturbation of phosphatidylethanolamine synthesis affects mitochondrial morphology and cell-cycle progression in procyclic-form Trypanosoma brucei. Mol Microbiol 2009 0.95
63 Cell morphogenesis of Trypanosoma brucei requires the paralogous, differentially expressed calpain-related proteins CAP5.5 and CAP5.5V. Protist 2009 0.94
64 The evolution of land plant cilia. New Phytol 2012 0.94
65 A protein-protein interaction map of the Trypanosoma brucei paraflagellar rod. PLoS One 2009 0.94
66 Detailed interrogation of trypanosome cell biology via differential organelle staining and automated image analysis. BMC Biol 2012 0.94
67 Intracellular positioning of isoforms explains an unusually large adenylate kinase gene family in the parasite Trypanosoma brucei. J Biol Chem 2005 0.94
68 RNA interference mutant induction in vivo demonstrates the essential nature of trypanosome flagellar function during mammalian infection. Eukaryot Cell 2007 0.94
69 Blocking variant surface glycoprotein synthesis in Trypanosoma brucei triggers a general arrest in translation initiation. PLoS One 2009 0.94
70 Conservation of ciliary proteins in plants with no cilia. BMC Plant Biol 2011 0.91
71 A new function of Trypanosoma brucei mitochondrial topoisomerase II is to maintain kinetoplast DNA network topology. Mol Microbiol 2008 0.91
72 Functional characterization of cohesin subunit SCC1 in Trypanosoma brucei and dissection of mutant phenotypes in two life cycle stages. Mol Microbiol 2008 0.90
73 Relationships between the major kinetoplastid paraflagellar rod proteins: a consolidating nomenclature. Mol Biochem Parasitol 2004 0.90
74 WCB is a C2 domain protein defining the plasma membrane - sub-pellicular microtubule corset of kinetoplastid parasites. Protist 2007 0.90
75 Calmodulin is required for paraflagellar rod assembly and flagellum-cell body attachment in trypanosomes. Protist 2013 0.90
76 The expanded Kinesin-13 repertoire of trypanosomes contains only one mitotic Kinesin indicating multiple extra-nuclear roles. PLoS One 2010 0.89
77 Analysis of the trypanosome flagellar proteome using a combined electron transfer/collisionally activated dissociation strategy. J Am Soc Mass Spectrom 2008 0.88
78 A cell-body groove housing the new flagellum tip suggests an adaptation of cellular morphogenesis for parasitism in the bloodstream form of Trypanosoma brucei. J Cell Sci 2013 0.88
79 Modes of flagellar assembly in Chlamydomonas reinhardtii and Trypanosoma brucei. Elife 2014 0.88
80 Bioinformatic insights to the ESAG5 and GRESAG5 gene families in kinetoplastid parasites. Mol Biochem Parasitol 2008 0.87
81 Ultrastructural investigation methods for Trypanosoma brucei. Methods Cell Biol 2010 0.87
82 Cytokinesis in trypanosomes. Cytoskeleton (Hoboken) 2012 0.87
83 Functional studies of an evolutionarily conserved, cytochrome b5 domain protein reveal a specific role in axonemal organisation and the general phenomenon of post-division axonemal growth in trypanosomes. Cell Motil Cytoskeleton 2009 0.86
84 Identification of a crenarchaeal orthologue of Elf1: implications for chromatin and transcription in Archaea. Biol Direct 2009 0.86
85 A post-assembly structural modification to the lumen of flagellar microtubule doublets. Curr Biol 2006 0.86
86 Identification and characterization of two trypanosome TFIIS proteins exhibiting particular domain architectures and differential nuclear localizations. Mol Microbiol 2008 0.85
87 Ab initio identification of novel regulatory elements in the genome of Trypanosoma brucei by Bayesian inference on sequence segmentation. PLoS One 2011 0.85
88 Depletion of mitochondrial acyl carrier protein in bloodstream-form Trypanosoma brucei causes a kinetoplast segregation defect. Eukaryot Cell 2011 0.85
89 Evidence for a sliding-resistance at the tip of the trypanosome flagellum. Cell Motil Cytoskeleton 2006 0.84
90 Mitochondrial shape and function in trypanosomes requires the outer membrane protein, TbLOK1. Mol Microbiol 2013 0.84
91 A Trypanosoma brucei protein required for maintenance of the flagellum attachment zone and flagellar pocket ER domains. Protist 2011 0.84
92 The mitotic stability of the minichromosomes of Trypanosoma brucei. Mol Biochem Parasitol 2003 0.83
93 Comparative genomics and concerted evolution of beta-tubulin paralogs in Leishmania spp. BMC Genomics 2006 0.83
94 Proteomics and the Trypanosoma brucei cytoskeleton: advances and opportunities. Parasitology 2012 0.79
95 The trypanosomatid-specific N terminus of RPA2 is required for RNA polymerase I assembly, localization, and function. Eukaryot Cell 2012 0.79
96 An expanded family of proteins with BPI/LBP/PLUNC-like domains in trypanosome parasites: an association with pathogenicity? Biochem Soc Trans 2011 0.77