Published in Circ Res on July 27, 2006
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Glia maturation factor-γ negatively modulates TLR4 signaling by facilitating TLR4 endocytic trafficking in macrophages. J Immunol (2013) 0.80
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Diabetes-Related Ankyrin Repeat Protein (DARP/Ankrd23) Modifies Glucose Homeostasis by Modulating AMPK Activity in Skeletal Muscle. PLoS One (2015) 0.76
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Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
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Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
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Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-wide association meta-analysis involving more than 22 000 cases and 60 000 controls. Circ Cardiovasc Genet (2010) 3.15
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Retracted Effects of valsartan on morbidity and mortality in uncontrolled hypertensive patients with high cardiovascular risks: KYOTO HEART Study. Eur Heart J (2009) 2.83
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Susceptibility locus for clinical and subclinical coronary artery disease at chromosome 9p21 in the multi-ethnic ADVANCE study. Hum Mol Genet (2008) 2.71
Controlled delivery of basic fibroblast growth factor promotes human cardiosphere-derived cell engraftment to enhance cardiac repair for chronic myocardial infarction. J Am Coll Cardiol (2008) 2.70
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Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans. Diabetes (2010) 2.44
Network analysis of human in-stent restenosis. Circulation (2006) 2.27
The endogenous peptide apelin potently improves cardiac contractility and reduces cardiac loading in vivo. Cardiovasc Res (2005) 2.24
Erythropoietin-mobilized endothelial progenitors enhance reendothelialization via Akt-endothelial nitric oxide synthase activation and prevent neointimal hyperplasia. Circ Res (2006) 2.19
Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. J Am Coll Cardiol (2010) 2.17
Endothelial lipase is a major determinant of HDL level. J Clin Invest (2003) 2.12
Del-1, an endogenous leukocyte-endothelial adhesion inhibitor, limits inflammatory cell recruitment. Science (2008) 2.10
Differences in vascular bed disease susceptibility reflect differences in gene expression response to atherogenic stimuli. Circ Res (2005) 2.10
A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium. Diabetes (2011) 2.09
Characterizing the admixed African ancestry of African Americans. Genome Biol (2009) 2.01
Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis. J Clin Invest (2008) 1.89
Antibody against interleukin-6 receptor attenuates left ventricular remodelling after myocardial infarction in mice. Cardiovasc Res (2010) 1.76
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet (2013) 1.72
Statin and beta-blocker therapy and the initial presentation of coronary heart disease. Ann Intern Med (2006) 1.72
Long-term clinical outcome after intramuscular implantation of bone marrow mononuclear cells (Therapeutic Angiogenesis by Cell Transplantation [TACT] trial) in patients with chronic limb ischemia. Am Heart J (2008) 1.70
Apelin-APJ signaling is a critical regulator of endothelial MEF2 activation in cardiovascular development. Circ Res (2013) 1.68
Hepatic proprotein convertases modulate HDL metabolism. Cell Metab (2007) 1.68
Therapeutic lymphangiogenesis with human recombinant VEGF-C. FASEB J (2002) 1.67
Novel role for the potent endogenous inotrope apelin in human cardiac dysfunction. Circulation (2003) 1.66
Retracted Angiogenesis by implantation of peripheral blood mononuclear cells and platelets into ischemic limbs. Circulation (2002) 1.65
MicroRNA-26a is a novel regulator of vascular smooth muscle cell function. J Cell Physiol (2011) 1.64
Amelioration of diabetic peripheral neuropathy by implantation of hematopoietic mononuclear cells in streptozotocin-induced diabetic rats. Exp Neurol (2005) 1.57
Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained. PLoS Genet (2013) 1.57
Chronotropic incompetence and autonomic dysfunction in patients without structural heart disease. Europace (2010) 1.55
In vivo genetic profiling and cellular localization of apelin reveals a hypoxia-sensitive, endothelial-centered pathway activated in ischemic heart failure. Am J Physiol Heart Circ Physiol (2007) 1.54
Endothelial lipase modulates susceptibility to atherosclerosis in apolipoprotein-E-deficient mice. J Biol Chem (2004) 1.54
Mechanism for IL-1 beta-mediated neovascularization unmasked by IL-1 beta knock-out mice. J Mol Cell Cardiol (2004) 1.51
Deficiency of nectin-2 leads to cardiac fibrosis and dysfunction under chronic pressure overload. Hypertension (2009) 1.50
HMG-CoA reductase inhibition improves anti-aging klotho protein expression and arteriosclerosis in rats with chronic inhibition of nitric oxide synthesis. Int J Cardiol (2007) 1.48
Sodium restriction improves the gustatory threshold for salty taste in patients with chronic kidney disease. Kidney Int (2009) 1.46
Clinical characteristics and morphologic features of isolated noncompaction of the ventricular myocardium: electrocardiogram-gated magnetic resonance imaging can elucidate more accurate biventricular structures. Heart Vessels (2005) 1.45
The negative correlation between plasma adiponectin and blood pressure depends on obesity: a family-based association study in SAPPHIRe. Am J Hypertens (2008) 1.44
Endothelial FGF receptor signaling accelerates atherosclerosis. Am J Physiol Heart Circ Physiol (2010) 1.43
Epicardial calcineurin-NFAT signals through Smad2 to direct coronary smooth muscle cell and arterial wall development. Cardiovasc Res (2013) 1.40
Metabolic syndrome and early-onset coronary artery disease: is the whole greater than its parts? J Am Coll Cardiol (2006) 1.40
Heart rate variability in adult patients with isolated left ventricular noncompaction. Int J Cardiol (2005) 1.39
Identification of endothelial cell genes by combined database mining and microarray analysis. Physiol Genomics (2003) 1.39
Platelet endothelial aggregation receptor 1 (PEAR1), a novel epidermal growth factor repeat-containing transmembrane receptor, participates in platelet contact-induced activation. J Biol Chem (2005) 1.34
Endogenous regulation of cardiovascular function by apelin-APJ. Am J Physiol Heart Circ Physiol (2009) 1.34
Clonally amplified cardiac stem cells are regulated by Sca-1 signaling for efficient cardiovascular regeneration. J Cell Sci (2007) 1.33
MURC, a muscle-restricted coiled-coil protein that modulates the Rho/ROCK pathway, induces cardiac dysfunction and conduction disturbance. Mol Cell Biol (2008) 1.33
Two major QTLs and several others relate to factors of metabolic syndrome in the family blood pressure program. Hypertension (2005) 1.32
Pressure-mediated hypertrophy and mechanical stretch induces IL-1 release and subsequent IGF-1 generation to maintain compensative hypertrophy by affecting Akt and JNK pathways. Circ Res (2009) 1.31
Disruption of the apelin-APJ system worsens hypoxia-induced pulmonary hypertension. Arterioscler Thromb Vasc Biol (2011) 1.30
Measurement of insulin-mediated glucose uptake: direct comparison of the modified insulin suppression test and the euglycemic, hyperinsulinemic clamp. Metabolism (2012) 1.28
Insulin resistance independently predicts the progression of coronary artery calcification. Am Heart J (2009) 1.26
Sonoporation using microbubble BR14 promotes pDNA/siRNA transduction to murine heart. Biochem Biophys Res Commun (2005) 1.26
Dual in vivo magnetic resonance evaluation of magnetically labeled mouse embryonic stem cells and cardiac function at 1.5 t. Magn Reson Med (2006) 1.25
Increased plasma S100A12 (EN-RAGE) levels in patients with type 2 diabetes. J Clin Endocrinol Metab (2004) 1.25
Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes. Diabetes (2013) 1.25
Signature patterns of gene expression in mouse atherosclerosis and their correlation to human coronary disease. Physiol Genomics (2005) 1.22
Paracrine osteogenic signals via bone morphogenetic protein-2 accelerate the atherosclerotic intimal calcification in vivo. Arterioscler Thromb Vasc Biol (2010) 1.22
Retracted Aldosterone directly induces myocyte apoptosis through calcineurin-dependent pathways. Circulation (2004) 1.22
Myocardium-targeted delivery of endothelial progenitor cells by ultrasound-mediated microbubble destruction improves cardiac function via an angiogenic response. J Mol Cell Cardiol (2006) 1.21
Downregulation of Dicer expression by serum withdrawal sensitizes human endothelial cells to apoptosis. Am J Physiol Heart Circ Physiol (2008) 1.21
Genome-wide expression profiling of a cardiac pressure overload model identifies major metabolic and signaling pathway responses. J Mol Cell Cardiol (2004) 1.21
HMG-CoA reductase inhibitors up-regulate anti-aging klotho mRNA via RhoA inactivation in IMCD3 cells. Cardiovasc Res (2004) 1.20
Apelin is necessary for the maintenance of insulin sensitivity. Am J Physiol Endocrinol Metab (2009) 1.19
Apelin prevents aortic aneurysm formation by inhibiting macrophage inflammation. Am J Physiol Heart Circ Physiol (2009) 1.19
Very low frequency power of heart rate variability is a powerful predictor of clinical prognosis in patients with congestive heart failure. Circ J (2004) 1.19
Molecular isolation and characterization of a soluble isoform of activated leukocyte cell adhesion molecule that modulates endothelial cell function. J Biol Chem (2004) 1.18
Autologous bone-marrow mononuclear cell implantation improves endothelium-dependent vasodilation in patients with limb ischemia. Circulation (2004) 1.18
Polymorphisms in hypoxia inducible factor 1 and the initial clinical presentation of coronary disease. Am Heart J (2007) 1.18
Neovascularization of ischemic tissues by gene delivery of the extracellular matrix protein Del-1. J Clin Invest (2003) 1.17
Tree-structured supervised learning and the genetics of hypertension. Proc Natl Acad Sci U S A (2004) 1.17
MURC, a muscle-restricted coiled-coil protein, is involved in the regulation of skeletal myogenesis. Am J Physiol Cell Physiol (2008) 1.17