Published in Proc Natl Acad Sci U S A on October 17, 2011
Voltage-gated proton channels: molecular biology, physiology, and pathophysiology of the H(V) family. Physiol Rev (2013) 1.35
Construction and validation of a homology model of the human voltage-gated proton channel hHV1. J Gen Physiol (2013) 1.17
Hydrophobic plug functions as a gate in voltage-gated proton channels. Proc Natl Acad Sci U S A (2013) 1.01
Philosophy of voltage-gated proton channels. J R Soc Interface (2013) 0.90
Hv1 proton channel opening is preceded by a voltage-independent transition. Biophys J (2014) 0.88
H+-type and OH- -type biological protonic semiconductors and complementary devices. Sci Rep (2013) 0.86
Peregrination of the selectivity filter delineates the pore of the human voltage-gated proton channel hHV1. J Gen Physiol (2013) 0.86
Voltage-gated proton channels. Compr Physiol (2012) 0.85
Selectivity Mechanism of the Voltage-gated Proton Channel, HV1. Sci Rep (2015) 0.84
Voltage-Gated Proton Channels as Novel Drug Targets: From NADPH Oxidase Regulation to Sperm Biology. Antioxid Redox Signal (2014) 0.83
The Voltage-Gated Proton Channel: A Riddle, Wrapped in a Mystery, inside an Enigma. Biochemistry (2015) 0.83
Pado, a fluorescent protein with proton channel activity can optically monitor membrane potential, intracellular pH, and map gap junctions. Sci Rep (2016) 0.81
Tryptophan 207 is crucial to the unique properties of the human voltage-gated proton channel, hHV1. J Gen Physiol (2015) 0.81
Mechanosensitivity of a rapid bioluminescence reporter system assessed by atomic force microscopy. Biophys J (2015) 0.80
Consequences of dimerization of the voltage-gated proton channel. Prog Mol Biol Transl Sci (2013) 0.78
Insights into the structure and function of HV1 from a meta-analysis of mutation studies. J Gen Physiol (2016) 0.78
Structural revelations of the human proton channel. Proc Natl Acad Sci U S A (2015) 0.77
A contribution to the history of the proton channel. Wiley Interdiscip Rev Membr Transp Signal (2012) 0.77
Biophysical properties of the voltage gated proton channel H(V)1. Wiley Interdiscip Rev Membr Transp Signal (2012) 0.77
Evidence for functional diversity between the voltage-gated proton channel Hv1 and its closest related protein HVRP1. PLoS One (2014) 0.76
Obtaining spheroplasts of armored dinoflagellates and first single-channel recordings of their ion channels using patch-clamping. Mar Drugs (2014) 0.76
Identification of a vacuolar proton channel that triggers the bioluminescent flash in dinoflagellates. PLoS One (2017) 0.75
The intimate and controversial relationship between voltage-gated proton channels and the phagocyte NADPH oxidase. Immunol Rev (2016) 0.75
Electronic control of H(+) current in a bioprotonic device with Gramicidin A and Alamethicin. Nat Commun (2016) 0.75
The volume-regulated anion channel (LRRC8) in nodose neurons is sensitive to acidic pH. JCI Insight (2017) 0.75
Understanding Bioluminescence in Dinoflagellates-How Far Have We Come? Microorganisms (2013) 0.75
Molecular and functional characterization of the voltage-gated proton channel in zebrafish neutrophils. Physiol Rep (2017) 0.75
WebLogo: a sequence logo generator. Genome Res (2004) 59.58
Sequence logos: a new way to display consensus sequences. Nucleic Acids Res (1990) 36.74
Structural parts involved in activation and inactivation of the sodium channel. Nature (1989) 8.72
Voltage-sensing residues in the S2 and S4 segments of the Shaker K+ channel. Neuron (1996) 8.20
Contribution of the S4 segment to gating charge in the Shaker K+ channel. Neuron (1996) 8.11
PROMALS3D: a tool for multiple protein sequence and structure alignments. Nucleic Acids Res (2008) 7.16
Phosphoinositide phosphatase activity coupled to an intrinsic voltage sensor. Nature (2005) 6.85
A proton pore in a potassium channel voltage sensor reveals a focused electric field. Nature (2004) 5.66
A voltage sensor-domain protein is a voltage-gated proton channel. Science (2006) 5.07
Voltage-gated proton channels and other proton transfer pathways. Physiol Rev (2003) 5.06
A voltage-gated proton-selective channel lacking the pore domain. Nature (2006) 4.89
Alteration of voltage-dependence of Shaker potassium channel by mutations in the S4 sequence. Nature (1991) 4.60
eggNOG v2.0: extending the evolutionary genealogy of genes with enhanced non-supervised orthologous groups, species and functional annotations. Nucleic Acids Res (2009) 4.55
Electrostatic interactions of S4 voltage sensor in Shaker K+ channel. Neuron (1995) 4.49
A functionally defined model for the M2 proton channel of influenza A virus suggests a mechanism for its ion selectivity. Proc Natl Acad Sci U S A (1997) 4.03
A gating charge transfer center in voltage sensors. Science (2010) 3.60
Voltage-dependent proton transport by the voltage sensor of the Shaker K+ channel. Neuron (1997) 3.29
Voltage-sensing residues in the S4 region of a mammalian K+ channel. Nature (1991) 3.01
Histidine scanning mutagenesis of basic residues of the S4 segment of the shaker k+ channel. J Gen Physiol (2001) 2.79
The voltage-gated proton channel Hv1 has two pores, each controlled by one voltage sensor. Neuron (2008) 2.26
A voltage-gated H+ channel underlying pH homeostasis in calcifying coccolithophores. PLoS Biol (2011) 2.24
A Na+ channel mutation linked to hypokalemic periodic paralysis exposes a proton-selective gating pore. J Gen Physiol (2007) 2.10
Incremental reductions of positive charge within the S4 region of a voltage-gated K+ channel result in corresponding decreases in gating charge. Neuron (1992) 2.09
Multimeric nature of voltage-gated proton channels. Proc Natl Acad Sci U S A (2008) 2.00
Dimeric subunit stoichiometry of the human voltage-dependent proton channel Hv1. Proc Natl Acad Sci U S A (2008) 1.95
The voltage-activated hydrogen ion conductance in rat alveolar epithelial cells is determined by the pH gradient. J Gen Physiol (1995) 1.88
A dinoflagellate exploits toxins to immobilize prey prior to ingestion. Proc Natl Acad Sci U S A (2010) 1.79
Chemical rescue of histidine selectivity filter mutants of the M2 ion channel of influenza A virus. J Biol Chem (2005) 1.78
An aqueous H+ permeation pathway in the voltage-gated proton channel Hv1. Nat Struct Mol Biol (2010) 1.44
Detailed comparison of expressed and native voltage-gated proton channel currents. J Physiol (2008) 1.43
THE PURIFICATION AND PROPERTIES OF THE BIOLUMINESCENT SYSTEM IN GONYAULAX POLYEDRA. Arch Biochem Biophys (1963) 1.42
Aspartate 112 is the selectivity filter of the human voltage-gated proton channel. Nature (2011) 1.39
The subcellular origin of bioluminescence in Noctiluca miliaris. J Gen Physiol (1967) 1.29
Zinc inhibition of monomeric and dimeric proton channels suggests cooperative gating. J Physiol (2010) 1.29
A substrate-binding protein in the Gonyaulax bioluminescence reaction. Arch Biochem Biophys (1971) 1.23
Structure and relative potency of several karlotoxins from Karlodinium veneficum. J Nat Prod (2010) 1.20
Functionality of the voltage-gated proton channel truncated in S4. Proc Natl Acad Sci U S A (2009) 1.18
The role and structure of the carboxyl-terminal domain of the human voltage-gated proton channel Hv1. J Biol Chem (2010) 1.17
Voltage-activated proton currents in membrane patches of rat alveolar epithelial cells. J Physiol (1995) 1.14
Bioluminescence: mechanism and mode of control of scintillon activity. Proc Natl Acad Sci U S A (1972) 1.09
Bioluminescence: pH activity profiles of related luciferase fractions. Science (1968) 0.99
Characterization of the bioluminescent organelles in Gonyaulax polyedra (dinoflagellates) after fast-freeze fixation and antiluciferase immunogold staining. J Cell Biol (1987) 0.99
On the physical identity of scintillons: bioluminescent particles in Gonyaulax polyedra. J Cell Sci (1972) 0.96
II. Asynchronous Flash Initiation by a Propagated Triggering Potential. Science (1965) 0.95
Role of a luciferin-binding protein in the circadian bioluminescent reaction of Gonyaulax polyedra. J Biol Chem (1989) 0.94
Molecular and functional characterization of Hv1 proton channel in human granulocytes. PLoS One (2010) 0.92
Dinoflagellate bioluminescence: a comparative study of invitro components. J Cell Physiol (1976) 0.90
The flash-triggering action potential of the luminescent dinoflagellate Noctiluca. J Gen Physiol (1968) 0.89
Electrophysiological studies of a non-luminescent form of the dinoflagellate Noctiluca miliaris. J Cell Comp Physiol (1960) 0.88
Use of the dinoflagellate Karlodinium veneficum as a sustainable source of biodiesel production. J Ind Microbiol Biotechnol (2009) 0.84
Membrane resting and action potentials from a protozoan, Noctiluca scintillans. J Cell Physiol (1957) 0.83
The ultrastructural localization of luciferase in three bioluminescent dinoflagellates, two species of Pyrocystis, and Noctiluca, using anti-luciferase and immunogold labelling. J Cell Sci (1987) 0.82
Analysis of Codon Usage Patterns in Toxic Dinoflagellate Alexandrium tamarense through Expressed Sequence Tag Data. Comp Funct Genomics (2010) 0.81
Toxic marine flagellates; their occurrence and physiological effects on animals. J Gen Microbiol (1957) 0.79
The voltage dependence of NADPH oxidase reveals why phagocytes need proton channels. Nature (2003) 2.45
Digital holographic microscopy reveals prey-induced changes in swimming behavior of predatory dinoflagellates. Proc Natl Acad Sci U S A (2007) 1.83
A dinoflagellate exploits toxins to immobilize prey prior to ingestion. Proc Natl Acad Sci U S A (2010) 1.79
HVCN1 modulates BCR signal strength via regulation of BCR-dependent generation of reactive oxygen species. Nat Immunol (2010) 1.70
From stop to start: tandem gene arrangement, copy number and trans-splicing sites in the dinoflagellate Amphidinium carterae. PLoS One (2008) 1.65
Extracellular ATP induces oscillations of intracellular Ca2+ and membrane potential and promotes transcription of IL-6 in macrophages. Proc Natl Acad Sci U S A (2004) 1.65
Isolation and characterization of karlotoxin 1, a new amphipathic toxin from Karlodinium veneficum. Tetrahedron Lett (2008) 1.65
Two bioluminescent diptera: the North American Orfelia fultoni and the Australian Arachnocampa flava. Similar niche, different bioluminescence systems. Photochem Photobiol (2002) 1.65
The antibacterial activity of human neutrophils and eosinophils requires proton channels but not BK channels. J Gen Physiol (2006) 1.48
Voltage-gated proton channels maintain pH in human neutrophils during phagocytosis. Proc Natl Acad Sci U S A (2009) 1.39
Aspartate 112 is the selectivity filter of the human voltage-gated proton channel. Nature (2011) 1.39
Sustained activation of proton channels and NADPH oxidase in human eosinophils and murine granulocytes requires PKC but not cPLA2 alpha activity. J Physiol (2006) 1.32
The expanding role of marine microbes in pharmaceutical development. Curr Opin Biotechnol (2010) 1.30
A pH-stabilizing role of voltage-gated proton channels in IgE-mediated activation of human basophils. Proc Natl Acad Sci U S A (2008) 1.30
Structure and absolute configuration of karlotoxin-2, an ichthyotoxin from the marine dinoflagellate Karlodinium veneficum. J Am Chem Soc (2010) 1.29
Zinc inhibition of monomeric and dimeric proton channels suggests cooperative gating. J Physiol (2010) 1.29
Interaction with 14-3-3 proteins promotes functional expression of the potassium channels TASK-1 and TASK-3. J Physiol (2002) 1.24
Absence of proton channels in COS-7 cells expressing functional NADPH oxidase components. J Gen Physiol (2002) 1.23
Structure and relative potency of several karlotoxins from Karlodinium veneficum. J Nat Prod (2010) 1.20
The pH dependence of NADPH oxidase in human eosinophils. J Physiol (2005) 1.19
Construction and validation of a homology model of the human voltage-gated proton channel hHV1. J Gen Physiol (2013) 1.17
The gp91phox component of NADPH oxidase is not a voltage-gated proton channel. J Gen Physiol (2002) 1.14
Taurine supplementation of plant derived protein and n-3 fatty acids are critical for optimal growth and development of cobia, Rachycentron canadum. Lipids (2013) 1.07
Genome-wide analysis of redox-regulated genes in a dinoflagellate. Gene (2003) 1.07
Effects of endocrine disrupting chemicals on the expression of CYP19 genes in zebrafish (Danio rerio) juveniles. Aquat Toxicol (2004) 1.07
Identification of Thr29 as a critical phosphorylation site that activates the human proton channel Hvcn1 in leukocytes. J Biol Chem (2009) 1.07
"Host tissue damage" signal ATP promotes non-directional migration and negatively regulates toll-like receptor signaling in human monocytes. J Biol Chem (2005) 1.06
Responses of Nannochloropsis oceanica IMET1 to Long-Term Nitrogen Starvation and Recovery. Plant Physiol (2013) 1.04
Novel bacterial isolate from Permian groundwater, capable of aggregating potential biofuel-producing microalga Nannochloropsis oceanica IMET1. Appl Environ Microbiol (2011) 0.99
Localization and expression of aromatase mRNA in adult zebrafish. Gen Comp Endocrinol (2004) 0.99
Temperature dependence of NADPH oxidase in human eosinophils. J Physiol (2003) 0.98
Molecular evolution of dinoflagellate luciferases, enzymes with three catalytic domains in a single polypeptide. Proc Natl Acad Sci U S A (2004) 0.97
The intimate and mysterious relationship between proton channels and NADPH oxidase. FEBS Lett (2008) 0.97
Effect of dietary probiotics on clownfish: a molecular approach to define how lactic acid bacteria modulate development in a marine fish. Am J Physiol Regul Integr Comp Physiol (2009) 0.95
Quorum sensing on a global scale: massive numbers of bioluminescent bacteria make milky seas. Appl Environ Microbiol (2006) 0.91
Alveolate phylogeny inferred using concatenated ribosomal proteins. J Eukaryot Microbiol (2011) 0.90
Algal toxins alter copepod feeding behavior. PLoS One (2012) 0.89
Two different domains of the luciferase gene in the heterotrophic dinoflagellate Noctiluca scintillans occur as two separate genes in photosynthetic species. Proc Natl Acad Sci U S A (2006) 0.89
A novel function for a carotenoid: astaxanthin used as a polarizer for visual signalling in a mantis shrimp. J Exp Biol (2012) 0.89
Differences in the toxicity of six Gambierdiscus (Dinophyceae) species measured using an in vitro human erythrocyte lysis assay. Toxicon (2013) 0.88
Voltage-gated proton channels help regulate pHi in rat alveolar epithelium. Am J Physiol Lung Cell Mol Physiol (2004) 0.88
Pharmacology of voltage-gated proton channels. Curr Pharm Des (2007) 0.88
Crystal structure of a pH-regulated luciferase catalyzing the bioluminescent oxidation of an open tetrapyrrole. Proc Natl Acad Sci U S A (2005) 0.86
Effect of dietary fatty acid composition on depot fat and exercise performance in a migrating songbird, the red-eyed vireo. J Exp Biol (2005) 0.86
Peregrination of the selectivity filter delineates the pore of the human voltage-gated proton channel hHV1. J Gen Physiol (2013) 0.86
Strong glucose dependence of electron current in human monocytes. Am J Physiol Cell Physiol (2011) 0.85
Digestive organ sizes and enzyme activities of refueling western sandpipers (Calidris mauri): contrasting effects of season and age. Physiol Biochem Zool (2005) 0.84
Lifetimes of mRNAs for clock-regulated proteins in a dinoflagellate. Chronobiol Int (2003) 0.83
Microbial diversity associated with odor modification for production of fertilizers from chicken litter. Appl Environ Microbiol (2006) 0.83
Oligomerization of the voltage-gated proton channel. Channels (Austin) (2010) 0.83
Subunit-dependent modulation of the 5-hydroxytryptamine type 3 receptor open-close equilibrium by n-alcohols. J Pharmacol Exp Ther (2007) 0.83
Conservation in the first internal transcribed spacer (ITS1) region of Hematodinium perezi (genotype III) from Callinectes sapidus . Dis Aquat Organ (2013) 0.82
Tissue essential fatty acid composition and competitive response to dietary manipulations in white bass (Morone chrysops), striped bass (M. saxatilis) and hybrid striped bass (M. chrysopsxM. saxatilis). Comp Biochem Physiol B Biochem Mol Biol (2003) 0.79
Diversity of Eukaryotic Translational Initiation Factor eIF4E in Protists. Comp Funct Genomics (2012) 0.79
Expressed sequence tags from Amoebophrya sp. infecting Karlodinium veneficum: comparing host and parasite sequences. J Eukaryot Microbiol (2009) 0.79
Variation in plasma lipids during the reproductive cycle of male and female desert tortoises, Gopherus agassizii. J Exp Zool (2002) 0.78
Diet preferences for specific fatty acids and their effect on composition of fat reserves in migratory Red-eyed Vireos (Vireo olivaceous). Comp Biochem Physiol A Mol Integr Physiol (2004) 0.77
A type-1 phosphoprotein phosphatase from a dinoflagellate as a possible component of the circadian mechanism. J Biol Rhythms (2003) 0.77
Analysis of electrophysiological properties and responses of neutrophils. Methods Mol Biol (2014) 0.76
Characterization and crystallization of active domains of a novel luciferase from a marine dinoflagellate. Acta Crystallogr D Biol Crystallogr (2003) 0.76
Unintended consequences at NIH. Science (2009) 0.75
Geographic variation in egg size and lipid provisioning in the diamondback terrapin Malaclemys terrapin. Physiol Biochem Zool (2012) 0.75
Interactions among contaminants and nutritional lipids during mobilization by digestive fluids of marine invertebrates. Environ Sci Technol (2003) 0.75
Does alligator testis produce estradiol? A comparison of ovarian and testicular aromatase. Biol Reprod (2003) 0.75