Published in Development on October 17, 2011
VEGF signaling inside vascular endothelial cells and beyond. Curr Opin Cell Biol (2012) 1.44
MicroRNAs Establish Uniform Traits during the Architecture of Vertebrate Embryos. Dev Cell (2017) 1.40
miRNA-27b targets vascular endothelial growth factor C to inhibit tumor progression and angiogenesis in colorectal cancer. PLoS One (2013) 1.31
A truncation allele in vascular endothelial growth factor c reveals distinct modes of signaling during lymphatic and vascular development. Development (2013) 1.01
Therapeutic angiogenesis: controlled delivery of angiogenic factors. Ther Deliv (2012) 0.97
The role of the VEGF-C/VEGFRs axis in tumor progression and therapy. Int J Mol Sci (2012) 0.97
The importance of microglia in the development of the vasculature in the central nervous system. Vasc Cell (2013) 0.95
Tip cell-specific requirement for an atypical Gpr124- and Reck-dependent Wnt/β-catenin pathway during brain angiogenesis. Elife (2015) 0.95
Paracrine factors from adipose-mesenchymal stem cells enhance metastatic capacity through Wnt signaling pathway in a colon cancer cell co-culture model. Cancer Cell Int (2015) 0.88
The transcription factor Atonal homolog 8 regulates Gata4 and Friend of Gata-2 during vertebrate development. J Biol Chem (2013) 0.88
Excessive vascular sprouting underlies cerebral hemorrhage in mice lacking αVβ8-TGFβ signaling in the brain. Development (2014) 0.85
Transforming Growth Factor β Drives Hemogenic Endothelium Programming and the Transition to Hematopoietic Stem Cells. Dev Cell (2016) 0.84
Compensatory angiogenesis and tumor refractoriness. Oncogenesis (2015) 0.83
Genistein suppresses FLT4 and inhibits human colorectal cancer metastasis. Oncotarget (2015) 0.82
Epigenetic regulation of hematopoiesis by DNA methylation. Elife (2016) 0.81
Kremen1 restricts Dkk activity during posterior lateral line development in zebrafish. Development (2014) 0.81
Low-dose 6-bromoindirubin-3'-oxime induces partial dedifferentiation of endothelial cells to promote increased neovascularization. Stem Cells (2014) 0.80
'In parallel' interconnectivity of the dorsal longitudinal anastomotic vessels requires both VEGF signaling and circulatory flow. J Cell Sci (2012) 0.80
Activated amelogenin Y-linked (AMELY) regulation and angiogenesis in human hepatocellular carcinoma by biocomputation. Oncol Lett (2013) 0.80
Canonical Wnt signalling regulates epithelial patterning by modulating levels of laminins in zebrafish appendages. Development (2014) 0.78
Correction: The importance of microglia in the development of the vasculature in the central nervous system. Vasc Cell (2013) 0.77
R-spondin 1/dickkopf-1/beta-catenin machinery is involved in testicular embryonic angiogenesis. PLoS One (2015) 0.75
The Transcription Factor Bach1 Suppresses the Developmental Angiogenesis of Zebrafish. Oxid Med Cell Longev (2017) 0.75
Cell Adhesion Mediated by VCAM-ITGα9 Interactions Enables Lymphatic Development. Arterioscler Thromb Vasc Biol (2015) 0.75
R-spondin-1 is required for specification of hematopoietic stem cells through Wnt16 and Vegfa signaling pathways. Development (2017) 0.75
Crosstalk between Stem and Progenitor Cellular Mediators with Special Emphasis on Vasculogenesis. Transfus Med Hemother (2017) 0.75
Stages of embryonic development of the zebrafish. Dev Dyn (1995) 42.72
VEGF receptor signalling - in control of vascular function. Nat Rev Mol Cell Biol (2006) 12.09
Identification of FAP locus genes from chromosome 5q21. Science (1991) 11.41
The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway. Proc Natl Acad Sci U S A (1999) 10.75
Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature (2007) 9.09
The Tol2kit: a multisite gateway-based construction kit for Tol2 transposon transgenesis constructs. Dev Dyn (2007) 8.86
Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors. Proc Natl Acad Sci U S A (2003) 7.60
Autocrine VEGF signaling is required for vascular homeostasis. Cell (2007) 7.37
Proximal events in Wnt signal transduction. Nat Rev Mol Cell Biol (2009) 6.66
The many ways of Wnt in cancer. Curr Opin Genet Dev (2007) 6.29
Notch signaling is required for arterial-venous differentiation during embryonic vascular development. Development (2001) 5.46
Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation. Nature (2008) 5.15
Cardiovascular failure in mouse embryos deficient in VEGF receptor-3. Science (1998) 5.07
Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair. Cell (2004) 5.04
Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries. Nature (2007) 4.65
GSK-3-selective inhibitors derived from Tyrian purple indirubins. Chem Biol (2003) 4.60
Endothelial tubes assemble from intracellular vacuoles in vivo. Nature (2006) 4.46
Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting. Proc Natl Acad Sci U S A (2007) 4.27
Proteolytic processing regulates receptor specificity and activity of VEGF-C. EMBO J (1997) 4.07
The vascular anatomy of the developing zebrafish: an atlas of embryonic and early larval development. Dev Biol (2001) 4.04
Lymphangiogenesis and cancer metastasis. Nat Rev Cancer (2002) 3.90
Canonical Wnt signaling regulates organ-specific assembly and differentiation of CNS vasculature. Science (2008) 3.86
Mesodermal Wnt2b signalling positively regulates liver specification. Nature (2006) 3.69
Gridlock, a localized heritable vascular patterning defect in the zebrafish. Nat Med (1995) 3.59
R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6. Proc Natl Acad Sci U S A (2007) 3.24
Wnt/beta-catenin signaling controls development of the blood-brain barrier. J Cell Biol (2008) 3.22
Regulation of vascular morphogenesis by Notch signaling. Genes Dev (2007) 3.10
The Wnt/beta-catenin pathway regulates cardiac valve formation. Nature (2003) 2.89
Distinct genetic interactions between multiple Vegf receptors are required for development of different blood vessel types in zebrafish. Proc Natl Acad Sci U S A (2006) 2.89
Wnt7b regulates mesenchymal proliferation and vascular development in the lung. Development (2002) 2.88
Arterial-venous segregation by selective cell sprouting: an alternative mode of blood vessel formation. Science (2009) 2.82
Gateway compatible vectors for analysis of gene function in the zebrafish. Dev Dyn (2007) 2.74
R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis. Dev Cell (2004) 2.73
Norrin, frizzled-4, and Lrp5 signaling in endothelial cells controls a genetic program for retinal vascularization. Cell (2009) 2.63
phospholipase C gamma-1 is required downstream of vascular endothelial growth factor during arterial development. Genes Dev (2003) 2.62
Disruption of acvrl1 increases endothelial cell number in zebrafish cranial vessels. Development (2002) 2.61
R-spondin1 is a high affinity ligand for LRP6 and induces LRP6 phosphorylation and beta-catenin signaling. J Biol Chem (2007) 2.61
Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression. J Biol Chem (2006) 2.61
Targeted disruption of the Wnt2 gene results in placentation defects. Development (1996) 2.59
Notch-responsive cells initiate the secondary transition in larval zebrafish pancreas. Mech Dev (2009) 2.57
R-Spondin proteins: a novel link to beta-catenin activation. Cell Cycle (2006) 2.56
TSPAN12 regulates retinal vascular development by promoting Norrin- but not Wnt-induced FZD4/beta-catenin signaling. Cell (2009) 2.53
Regulation of vascular endothelial growth factor by the Wnt and K-ras pathways in colonic neoplasia. Cancer Res (2001) 2.47
Wnt signaling: an essential regulator of cardiovascular differentiation, morphogenesis and progenitor self-renewal. Development (2008) 2.46
R-Spondin family members regulate the Wnt pathway by a common mechanism. Mol Biol Cell (2008) 2.37
Mouse Wnt receptor gene Fzd5 is essential for yolk sac and placental angiogenesis. Development (2001) 2.19
Viral 2A peptides allow expression of multiple proteins from a single ORF in transgenic zebrafish embryos. Genesis (2007) 2.12
A conserved molecular pathway mediates myoblast fusion in insects and vertebrates. Nat Genet (2007) 2.10
The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling. Dev Cell (2010) 2.01
The role of wnt signaling in physiological and pathological angiogenesis. Circ Res (2010) 1.95
Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells. Nature (2011) 1.91
Rspo3 binds syndecan 4 and induces Wnt/PCP signaling via clathrin-mediated endocytosis to promote morphogenesis. Dev Cell (2011) 1.83
Signaling pathways in vascular development. Annu Rev Cell Dev Biol (2002) 1.76
Vascular endothelial growth factor receptor 3 is involved in tumor angiogenesis and growth. Cancer Res (2007) 1.73
Local guidance of emerging vessel sprouts requires soluble Flt-1. Dev Cell (2009) 1.72
Wnt/Frizzled signaling in angiogenesis. Angiogenesis (2008) 1.71
R-spondin 2 is required for normal laryngeal-tracheal, lung and limb morphogenesis. Development (2008) 1.66
The Wnt signaling regulator R-spondin 3 promotes angioblast and vascular development. Development (2008) 1.59
R-spondin3 is required for mouse placental development. Dev Biol (2006) 1.58
Glycogen-Synthase Kinase3beta/beta-catenin axis promotes angiogenesis through activation of vascular endothelial growth factor signaling in endothelial cells. Circ Res (2005) 1.56
Vegfc/Flt4 signalling is suppressed by Dll4 in developing zebrafish intersegmental arteries. Development (2009) 1.51
The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis. J Clin Invest (2003) 1.51
Deletion of vascular endothelial growth factor C (VEGF-C) and VEGF-D is not equivalent to VEGF receptor 3 deletion in mouse embryos. Mol Cell Biol (2008) 1.47
Very low density lipoprotein receptor, a negative regulator of the wnt signaling pathway and choroidal neovascularization. J Biol Chem (2007) 1.45
Transgenic induction of vascular endothelial growth factor-C is strongly angiogenic in mouse embryos but leads to persistent lymphatic hyperplasia in adult tissues. Am J Pathol (2008) 1.38
Adenomatous polyposis coli-deficient zebrafish are susceptible to digestive tract neoplasia. EMBO Rep (2006) 1.33
Dynamic expression of R-spondin family genes in mouse development. Gene Expr Patterns (2006) 1.30
Combinatorial interaction between CCM pathway genes precipitates hemorrhagic stroke. Dis Model Mech (2008) 1.23
Vascular morphogenesis: a Wnt for every vessel? Curr Opin Genet Dev (2009) 1.22
Vegfc is required for vascular development and endoderm morphogenesis in zebrafish. EMBO Rep (2004) 1.21
Non-conventional Frizzled ligands and Wnt receptors. Dev Growth Differ (2008) 1.20
Wnt2 coordinates the commitment of mesoderm to hematopoietic, endothelial, and cardiac lineages in embryoid bodies. J Biol Chem (2006) 1.18
An essential role for frizzled 5 in mammalian ocular development. Development (2008) 1.11
Endothelial cells create a hematopoietic inductive microenvironment preferential to erythropoiesis in the mouse spleen. Cell Struct Funct (1991) 1.05
Wnt1 and Wnt5a affect endothelial proliferation and capillary length; Wnt2 does not. Growth Factors (2007) 1.03
Autocrine loop between vascular endothelial growth factor (VEGF)-C and VEGF receptor-3 positively regulates tumor-associated lymphangiogenesis in oral squamoid cancer cells. Am J Pathol (2009) 0.95
In vivo imaging of embryonic vascular development using transgenic zebrafish. Dev Biol (2002) 11.62
sonic hedgehog and vascular endothelial growth factor act upstream of the Notch pathway during arterial endothelial differentiation. Dev Cell (2002) 5.66
Endothelial tubes assemble from intracellular vacuoles in vivo. Nature (2006) 4.46
The control of vascular integrity by endothelial cell junctions: molecular basis and pathological implications. Dev Cell (2009) 3.87
Cardiac troponin T is essential in sarcomere assembly and cardiac contractility. Nat Genet (2002) 3.81
Angiogenic network formation in the developing vertebrate trunk. Development (2003) 3.66
Semaphorin-plexin signaling guides patterning of the developing vasculature. Dev Cell (2004) 2.62
phospholipase C gamma-1 is required downstream of vascular endothelial growth factor during arterial development. Genes Dev (2003) 2.62
Disruption of acvrl1 increases endothelial cell number in zebrafish cranial vessels. Development (2002) 2.61
Live imaging of lymphatic development in the zebrafish. Nat Med (2006) 2.51
Arterial-venous specification during development. Circ Res (2009) 2.49
Arteries and veins: making a difference with zebrafish. Nat Rev Genet (2002) 2.31
Combinatorial function of ETS transcription factors in the developing vasculature. Dev Biol (2006) 2.22
Resynchronization therapy in pediatric and congenital heart disease patients: an international multicenter study. J Am Coll Cardiol (2005) 1.90
An essential role for Fgfs in endodermal pouch formation influences later craniofacial skeletal patterning. Development (2004) 1.63
Zebrafish as a new animal model to study lymphangiogenesis. Anat Sci Int (2009) 1.56
A nonsense mutation in zebrafish gata1 causes the bloodless phenotype in vlad tepes. Proc Natl Acad Sci U S A (2002) 1.52
Molecular distinction between arteries and veins. Cell Tissue Res (2003) 1.47
Genetic determinants of hyaloid and retinal vasculature in zebrafish. BMC Dev Biol (2007) 1.40
A placebo-controlled test of cognitive-behavioral therapy for comorbid insomnia in older adults. J Consult Clin Psychol (2005) 1.37
Essential and overlapping roles for laminin alpha chains in notochord and blood vessel formation. Dev Biol (2006) 1.32
The zebrafish kohtalo/trap230 gene is required for the development of the brain, neural crest, and pronephric kidney. Proc Natl Acad Sci U S A (2005) 1.31
pak2a mutations cause cerebral hemorrhage in redhead zebrafish. Proc Natl Acad Sci U S A (2007) 1.28
Combinatorial interaction between CCM pathway genes precipitates hemorrhagic stroke. Dis Model Mech (2008) 1.23
Quality improvement guidelines for percutaneous management of the thrombosed or dysfunctional dialysis access. J Vasc Interv Radiol (2003) 1.23
Atypical scrapie in sheep from a UK research flock which is free from classical scrapie. BMC Vet Res (2009) 1.22
Clinical findings in two cases of atypical scrapie in sheep: a case report. BMC Vet Res (2007) 1.20
Loss of unc45a precipitates arteriovenous shunting in the aortic arches. Dev Biol (2008) 1.17
Improving identification and documentation of pressure ulcers at an urban academic hospital. Jt Comm J Qual Patient Saf (2011) 1.17
Vascular development in the zebrafish. Cold Spring Harb Perspect Med (2012) 1.16
Nf1 mutation expands an EGFR-dependent peripheral nerve progenitor that confers neurofibroma tumorigenic potential. Cell Stem Cell (2008) 1.15
reg6 is required for branching morphogenesis during blood vessel regeneration in zebrafish caudal fins. Dev Biol (2003) 1.14
Role of a SpoVA protein in dipicolinic acid uptake into developing spores of Bacillus subtilis. J Bacteriol (2012) 1.13
ApoB-containing lipoproteins regulate angiogenesis by modulating expression of VEGF receptor 1. Nat Med (2012) 1.12
Pruritus is a common feature in sheep infected with the BSE agent. BMC Vet Res (2008) 1.10
Self-association of Gata1 enhances transcriptional activity in vivo in zebra fish embryos. Mol Cell Biol (2003) 1.09
Coronary veins determine the pattern of sympathetic innervation in the developing heart. Development (2013) 1.09
Engagement and retention in services among formerly homeless adults with co-occurring mental illness and substance abuse: voices from the margins. Psychiatr Rehabil J (2008) 1.09
Chemokine signaling directs trunk lymphatic network formation along the preexisting blood vasculature. Dev Cell (2012) 1.08
The "surreptitious Staphylococcus": Staphylococcus lugdunensis endocarditis in a child. Pediatr Infect Dis J (2002) 1.07
Common factors regulating patterning of the nervous and vascular systems. Annu Rev Cell Dev Biol (2010) 1.07
Assembly and patterning of the vascular network of the vertebrate hindbrain. Development (2011) 1.04
TGFβ signaling is required for sprouting lymphangiogenesis during lymphatic network development in the skin. Development (2013) 1.03
The metalloproteinase inhibitor Reck is essential for zebrafish DRG development. Development (2012) 1.02
Latrotoxin receptor signaling engages the UNC-13-dependent vesicle-priming pathway in C. elegans. Curr Biol (2004) 1.02
Development of multilineage adult hematopoiesis in the zebrafish with a runx1 truncation mutation. Blood (2010) 1.02
Long-term time-lapse fluorescence imaging of developing zebrafish. Zebrafish (2005) 1.02
Resident cellular components of the human lung: current knowledge and goals for research on cell phenotyping and function. Proc Am Thorac Soc (2008) 1.02
The euryarchaeota, nature's medium for engineering of single-stranded DNA-binding proteins. J Biol Chem (2005) 1.01
Macrophage colony stimulating factor modulates the development of hematopoiesis by stimulating the differentiation of endothelial cells in the AGM region. Blood (2002) 0.99
Loss of BRCC3 deubiquitinating enzyme leads to abnormal angiogenesis and is associated with syndromic moyamoya. Am J Hum Genet (2011) 0.99
PDZ-RhoGEF and LARG are essential for embryonic development and provide a link between thrombin and LPA receptors and Rho activation. J Biol Chem (2013) 0.99
The molecular profiles of neural stem cell niche in the adult subventricular zone. PLoS One (2012) 0.97
Fishing for novel angiogenic therapies. Br J Pharmacol (2003) 0.97
The effect of stocking densities on reproductive performance in laboratory zebrafish (Danio rerio). Zebrafish (2011) 0.96
Disparities in the use of primary prevention and defibrillator therapy among blacks and women. Am J Med (2006) 0.96
Endothelial cells promote migration and proliferation of enteric neural crest cells via beta1 integrin signaling. Dev Biol (2009) 0.95
Lymphatic development. Birth Defects Res C Embryo Today (2009) 0.93
In their own words: trauma and substance abuse in the lives of formerly homeless women with serious mental illness. Am J Orthopsychiatry (2006) 0.93
Using an established telehealth model to train urban primary care providers on hypertension management. J Clin Hypertens (Greenwich) (2011) 0.92
Imaging blood vessels in the zebrafish. Methods Cell Biol (2010) 0.92
Zebrafish as a model for hemorrhagic stroke. Methods Cell Biol (2011) 0.92
Imaging blood vessels in the zebrafish. Methods Cell Biol (2004) 0.92
Conditional deletion of Ccm2 causes hemorrhage in the adult brain: a mouse model of human cerebral cavernous malformations. Hum Mol Genet (2011) 0.91
Neuronal action on the developing blood vessel pattern. Semin Cell Dev Biol (2011) 0.90
Visualization and experimental analysis of blood vessel formation using transgenic zebrafish. Birth Defects Res C Embryo Today (2007) 0.90
Racial differences in the association between self-rated health status and objective clinical measures among participants in the BARI 2D trial. Am J Public Health (2010) 0.90
The evaluation of exposure risks for natural transmission of scrapie within an infected flock. BMC Vet Res (2009) 0.89
Expression of a fibroblast growth factor-binding protein during the development of adenocarcinoma of the pancreas and colon. Cancer Res (2006) 0.89
Chapter 4. Using the zebrafish to study vessel formation. Methods Enzymol (2008) 0.89
The stability of literacy-related cognitive contributions to Chinese character naming and reading fluency. J Psycholinguist Res (2013) 0.88
Whole-mount immunohistochemical analysis for embryonic limb skin vasculature: a model system to study vascular branching morphogenesis in embryo. J Vis Exp (2011) 0.87
fused-somites-like mutants exhibit defects in trunk vessel patterning. Dev Dyn (2006) 0.86
Activity and regulation of various forms of CwlJ, SleB, and YpeB proteins in degrading cortex peptidoglycan of spores of Bacillus species in vitro and during spore germination. J Bacteriol (2013) 0.86
Identification of the fibroblast growth factor (FGF)-interacting domain in a secreted FGF-binding protein by phage display. J Biol Chem (2005) 0.86
Hand-carried cardiac ultrasound as a tool to screen for important cardiovascular disease in an underserved minority health care clinic. J Am Soc Echocardiogr (2004) 0.85
Identification and biological characterization of 6-aryl-7-isopropylquinazolinones as novel TRPV1 antagonists that are effective in models of chronic pain. J Med Chem (2006) 0.85
Metabolites of a tobacco-specific lung carcinogen in children exposed to secondhand or thirdhand tobacco smoke in their homes. Cancer Epidemiol Biomarkers Prev (2011) 0.85
A functional feature analysis on diverse protein-protein interactions: application for the prediction of binding affinity. J Comput Aided Mol Des (2014) 0.84
CDP-diacylglycerol synthetase-controlled phosphoinositide availability limits VEGFA signaling and vascular morphogenesis. Blood (2012) 0.84
Biochemical and structural characterization of the secreted chorismate mutase (Rv1885c) from Mycobacterium tuberculosis H37Rv: an *AroQ enzyme not regulated by the aromatic amino acids. J Bacteriol (2006) 0.84
Effect of FGF-binding protein 3 on vascular permeability. J Biol Chem (2008) 0.84
Methanosarcina acetivorans flap endonuclease 1 activity is inhibited by a cognate single-stranded-DNA-binding protein. J Bacteriol (2006) 0.83
Transcriptional signature of accessory cells in the lateral line, using the Tnk1bp1:EGFP transgenic zebrafish line. BMC Dev Biol (2012) 0.83
Reversal of warfarin-induced hemorrhage in the emergency department. West J Emerg Med (2011) 0.82
Development of phonological awareness in bilingual chinese children. J Psycholinguist Res (2008) 0.81
Down-regulation of MALAT1 inhibits cervical cancer cell invasion and metastasis by inhibition of epithelial-mesenchymal transition. Mol Biosyst (2016) 0.81
Perivascular hair follicle stem cells associate with a venule annulus. J Invest Dermatol (2013) 0.80
Developmental imaging: the avian embryo hatches to the challenge. Birth Defects Res C Embryo Today (2013) 0.80