Published in Growth Factors on February 01, 2007
Microwell-mediated control of embryoid body size regulates embryonic stem cell fate via differential expression of WNT5a and WNT11. Proc Natl Acad Sci U S A (2009) 2.56
Mesenchymal stem cells produce Wnt isoforms and TGF-beta1 that mediate proliferation and procollagen expression by lung fibroblasts. Am J Physiol Lung Cell Mol Physiol (2009) 1.30
Macrophages and angiogenesis: a role for Wnt signaling. Vasc Cell (2012) 1.12
Rspo1/Wnt signaling promotes angiogenesis via Vegfc/Vegfr3. Development (2011) 1.11
Activation of the planar cell polarity formin DAAM1 leads to inhibition of endothelial cell proliferation, migration, and angiogenesis. Proc Natl Acad Sci U S A (2010) 1.10
Microfibril-associate glycoprotein-2 (MAGP-2) promotes angiogenic cell sprouting by blocking notch signaling in endothelial cells. Microvasc Res (2008) 1.08
Differential gene expression in a coculture model of angiogenesis reveals modulation of select pathways and a role for Notch signaling. Physiol Genomics (2008) 1.05
NANOG induction of fetal liver kinase-1 (FLK1) transcription regulates endothelial cell proliferation and angiogenesis. Blood (2010) 1.04
Differential expression of Wnts after spinal cord contusion injury in adult rats. PLoS One (2011) 1.03
Cell-cell interaction in the heart via Wnt/β-catenin pathway after cardiac injury. Cardiovasc Res (2014) 0.98
Secreted frizzled-related protein 4: an angiogenesis inhibitor. Am J Pathol (2010) 0.94
Wnt3a Promotes the Vasculogenic Mimicry Formation of Colon Cancer via Wnt/β-Catenin Signaling. Int J Mol Sci (2015) 0.86
Control of vascular permeability by adhesion molecules. Tissue Barriers (2015) 0.81
Participation of WNT and β-Catenin in Physiological and Pathological Endometrial Changes: Association with Angiogenesis. Biomed Res Int (2015) 0.80
Wnt5a attenuates hypoxia-induced pulmonary arteriolar remodeling and right ventricular hypertrophy in mice. Exp Biol Med (Maywood) (2015) 0.78
Tumour cell-derived WNT5B modulates in vitro lymphangiogenesis via induction of partial endothelial-mesenchymal transition of lymphatic endothelial cells. Oncogene (2016) 0.75
Engineering vascularized skeletal muscle tissue. Nat Biotechnol (2005) 7.73
Soluble endoglin contributes to the pathogenesis of preeclampsia. Nat Med (2006) 6.21
VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment. J Clin Invest (2004) 5.59
Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells. Cell Stem Cell (2010) 4.21
Inflammation-induced lymphangiogenesis in the cornea arises from CD11b-positive macrophages. J Clin Invest (2005) 3.77
Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation. Genes Dev (2006) 3.72
Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms. J Clin Invest (2002) 3.70
Endogenous VEGF is required for visual function: evidence for a survival role on müller cells and photoreceptors. PLoS One (2008) 3.46
Notch function in the vasculature: insights from zebrafish, mouse and man. Bioessays (2004) 2.59
An essential role for RPE-derived soluble VEGF in the maintenance of the choriocapillaris. Proc Natl Acad Sci U S A (2009) 2.59
A Foxo/Notch pathway controls myogenic differentiation and fiber type specification. J Clin Invest (2007) 2.57
Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis. Development (2002) 2.57
Development and pathology of the hyaloid, choroidal and retinal vasculature. Int J Dev Biol (2004) 2.56
VEGF164-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization. J Exp Med (2003) 2.52
Crosstalk between tumor and endothelial cells promotes tumor angiogenesis by MAPK activation of Notch signaling. Cancer Cell (2005) 2.47
Decreased macrophage number and activation lead to reduced lymphatic vessel formation and contribute to impaired diabetic wound healing. Am J Pathol (2007) 2.27
New targets of beta-catenin signaling in the liver are involved in the glutamine metabolism. Oncogene (2002) 2.23
Vascular endothelial growth factor localization in the adult. Am J Pathol (2006) 2.20
Bile acid and inflammation activate gastric cardia stem cells in a mouse model of Barrett-like metaplasia. Cancer Cell (2012) 2.16
Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a. Proc Natl Acad Sci U S A (2003) 2.14
Regulation of cardiovascular development and integrity by the heart of glass-cerebral cavernous malformation protein pathway. Nat Med (2009) 2.12
Wnt/beta-catenin signaling induces proliferation, survival and interleukin-8 in human endothelial cells. Angiogenesis (2005) 2.01
Inhibition of Wnt-2-mediated signaling induces programmed cell death in non-small-cell lung cancer cells. Oncogene (2004) 1.93
Foxd1-dependent signals control cellularity in the renal capsule, a structure required for normal renal development. Development (2005) 1.84
Impaired angiogenesis and altered Notch signaling in mice overexpressing endothelial Egfl7. Blood (2010) 1.84
Wnt5a signaling induces proliferation and survival of endothelial cells in vitro and expression of MMP-1 and Tie-2. Mol Biol Cell (2006) 1.81
Notch-RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization. Nat Immunol (2012) 1.81
A notch1 ectodomain construct inhibits endothelial notch signaling, tumor growth, and angiogenesis. Cancer Res (2008) 1.80
WNT7a induces E-cadherin in lung cancer cells. Proc Natl Acad Sci U S A (2003) 1.78
Wnt signaling promotes oncogenic transformation by inhibiting c-Myc-induced apoptosis. J Cell Biol (2002) 1.75
Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice. J Clin Invest (2011) 1.74
IGF2: epigenetic regulation and role in development and disease. Cytokine Growth Factor Rev (2008) 1.73
Wnt/Frizzled signaling in angiogenesis. Angiogenesis (2008) 1.71
Wnt5a is required for proper epithelial-mesenchymal interactions in the uterus. Development (2004) 1.68
RhoA/ROCK signaling is essential for multiple aspects of VEGF-mediated angiogenesis. FASEB J (2010) 1.67
Tumor escape from endogenous, extracellular matrix-associated angiogenesis inhibitors by up-regulation of multiple proangiogenic factors. Clin Cancer Res (2008) 1.65
NF-kappaB regulation of endothelial cell function during LPS-induced toxemia and cancer. J Clin Invest (2006) 1.61
Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression. J Clin Invest (2007) 1.60
VEGF expression and receptor activation in the choroid during development and in the adult. Invest Ophthalmol Vis Sci (2006) 1.59
NLRP3 inflammasome activation in retinal pigment epithelial cells by lysosomal destabilization: implications for age-related macular degeneration. Invest Ophthalmol Vis Sci (2013) 1.58
Inhibition of Notch signaling ameliorates insulin resistance in a FoxO1-dependent manner. Nat Med (2011) 1.55
VEGF and TGF-beta are required for the maintenance of the choroid plexus and ependyma. J Exp Med (2008) 1.54
Cultured endothelial cells display endogenous activation of the canonical Wnt signaling pathway and express multiple ligands, receptors, and secreted modulators of Wnt signaling. Dev Dyn (2006) 1.54
A selective microRNA-based strategy inhibits restenosis while preserving endothelial function. J Clin Invest (2014) 1.52
Forty-year journey of angiogenesis translational research. Sci Transl Med (2011) 1.51
Analysis of hypoxia-related gene expression in sarcomas and effect of hypoxia on RNA interference of vascular endothelial cell growth factor A. Cancer Res (2005) 1.51
Notch1 deficiency results in decreased inflammation during wound healing and regulates vascular endothelial growth factor receptor-1 and inflammatory cytokine expression in macrophages. J Immunol (2010) 1.49
Roles for VEGF in the adult. Microvasc Res (2007) 1.48
beta-catenin/TCF/Lef controls a differentiation-associated transcriptional program in renal epithelial progenitors. Development (2007) 1.42
TGF-beta is required for vascular barrier function, endothelial survival and homeostasis of the adult microvasculature. PLoS One (2009) 1.38
Notch in mammary gland development and breast cancer. Semin Cancer Biol (2004) 1.36
Transcriptional regulation of vascular endothelial growth factor in cancer. Cytokine Growth Factor Rev (2005) 1.35
Endothelial Jagged-1 is necessary for homeostatic and regenerative hematopoiesis. Cell Rep (2013) 1.32
Notch oncoproteins depend on gamma-secretase/presenilin activity for processing and function. J Biol Chem (2004) 1.31
Wnt/Frizzled signaling in the vasculature: new angiogenic factors in sight. Physiology (Bethesda) (2006) 1.30
Notch signaling in primary endothelial cells. Ann N Y Acad Sci (2003) 1.29
Coordinated vascular endothelial growth factor expression and signaling during skeletal myogenic differentiation. Mol Biol Cell (2007) 1.26
Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1. J Immunol (2010) 1.25
Defective pulmonary development in the absence of heparin-binding vascular endothelial growth factor isoforms. Am J Respir Cell Mol Biol (2002) 1.25
Inhibition of Notch uncouples Akt activation from hepatic lipid accumulation by decreasing mTorc1 stability. Nat Med (2013) 1.23
Notch1 controls macrophage recruitment and Notch signaling is activated at sites of endothelial cell anastomosis during retinal angiogenesis in mice. Blood (2011) 1.22
A human- and male-specific protocadherin that acts through the wnt signaling pathway to induce neuroendocrine transdifferentiation of prostate cancer cells. Cancer Res (2005) 1.22
Role of shear-stress-induced VEGF expression in endothelial cell survival. J Cell Sci (2012) 1.21
Expression and role of VEGF in the adult retinal pigment epithelium. Invest Ophthalmol Vis Sci (2011) 1.21
Tips, stalks, tubes: notch-mediated cell fate determination and mechanisms of tubulogenesis during angiogenesis. Cold Spring Harb Perspect Med (2012) 1.21
Frizzled-9 is activated by Wnt-2 and functions in Wnt/beta -catenin signaling. J Biol Chem (2002) 1.20
Retinal pigment epithelium and endothelial cell interaction causes retinal pigment epithelial barrier dysfunction via a soluble VEGF-dependent mechanism. Exp Eye Res (2003) 1.19
Unique patterns of Notch1, Notch4 and Jagged1 expression in ovarian vessels during folliculogenesis and corpus luteum formation. Gene Expr Patterns (2005) 1.19
Pericyte isolation and use in endothelial/pericyte coculture models. Methods Enzymol (2008) 1.19
Chloride intracellular channel 4 is involved in endothelial proliferation and morphogenesis in vitro. Angiogenesis (2009) 1.17
Signal transduction in vasculogenesis and developmental angiogenesis. Int J Dev Biol (2011) 1.17
A role for Notch signaling in trophoblast endovascular invasion and in the pathogenesis of pre-eclampsia. Development (2011) 1.15
Inhibition of VEGF or TGF-{beta} signaling activates endothelium and increases leukocyte rolling. Arterioscler Thromb Vasc Biol (2009) 1.14
The role of hypoxia in vascular injury and repair. Annu Rev Pathol (2008) 1.14
Breast cancer cells secreted platelet-derived growth factor-induced motility of vascular smooth muscle cells is mediated through neuropilin-1. Mol Carcinog (2006) 1.13
Endothelial-mesenchymal interactions in vitro reveal molecular mechanisms of smooth muscle/pericyte differentiation. Stem Cells Dev (2004) 1.13
Endothelial cell-astrocyte interactions and TGF beta are required for induction of blood-neural barrier properties. Brain Res Dev Brain Res (2004) 1.13
Notch regulates the angiogenic response via induction of VEGFR-1. J Angiogenes Res (2010) 1.12
Proceedings of the Third International Symposium on Retinopathy of Prematurity: an update on ROP from the lab to the nursery (November 2003, Anaheim, California). Mol Vis (2006) 1.10
Contextual role for angiopoietins and TGFbeta1 in blood vessel stabilization. J Cell Sci (2007) 1.08
Epoxyeicosanoids promote organ and tissue regeneration. Proc Natl Acad Sci U S A (2013) 1.08
Vascular endothelial growth factor receptor 2-mediated angiogenesis is essential for gonadotropin-dependent follicle development. J Clin Invest (2003) 1.06
JAGGED1 signaling regulates hemangioma stem cell-to-pericyte/vascular smooth muscle cell differentiation. Arterioscler Thromb Vasc Biol (2011) 1.05
Notch modulates VEGF action in endothelial cells by inducing Matrix Metalloprotease activity. Vasc Cell (2011) 1.04
The vascular endothelial growth factor (VEGF)/VEGF receptor 2 pathway is critical for blood vessel survival in corpora lutea of pregnancy in the rodent. Endocrinology (2004) 1.04
Vascular endothelial growth factor receptor 2 (VEGFR-2) functions to promote uterine decidual angiogenesis during early pregnancy in the mouse. Endocrinology (2009) 1.03
Identification of genes involved in VEGF-mediated vascular morphogenesis using embryonic stem cell-derived cystic embryoid bodies. Lab Invest (2004) 1.02
Differential effects of VEGFR-1 and VEGFR-2 inhibition on tumor metastases based on host organ environment. Cancer Res (2010) 1.01
Arterial versus venous endothelial cells. Cell Tissue Res (2008) 1.01
Getting Tie(2)d up in angiogenesis. J Clin Invest (2002) 1.00
Notch1 functions as a negative regulator of lymphatic endothelial cell differentiation in the venous endothelium. Development (2013) 0.99
The role of RPE cell-associated VEGF₁₈₉ in choroidal endothelial cell transmigration across the RPE. Invest Ophthalmol Vis Sci (2011) 0.99
Vascular endothelial growth factor is important for brown adipose tissue development and maintenance. FASEB J (2013) 0.97
A brief history of anti-VEGF for the treatment of ocular angiogenesis. Am J Pathol (2012) 0.96
Wnt signaling in angiogenesis. Curr Drug Targets (2008) 0.95
Functional analysis of a mutant form of the receptor tyrosine kinase Tie2 causing venous malformations. J Mol Med (Berl) (2004) 0.95
Wnt and beta-catenin signaling target the expression of ecto-5'-nucleotidase and increase extracellular adenosine generation. Exp Cell Res (2004) 0.93
Notch signaling in developmental and tumor angiogenesis. Genes Cancer (2011) 0.93
A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma. Angiogenesis (2010) 0.92
Repression of vascular endothelial growth factor expression by the zinc finger transcription factor ZNF24. Cancer Res (2007) 0.92