Published in World J Diabetes on October 15, 2011
Fetal programming of body composition, obesity, and metabolic function: the role of intrauterine stress and stress biology. J Nutr Metab (2012) 1.07
Nutrition and neurodevelopment in children: focus on NUTRIMENTHE project. Eur J Nutr (2013) 0.91
Epigenetics and phenotypic variability: some interesting insights from birds. Genet Sel Evol (2013) 0.91
Epigenetic features in the oyster Crassostrea gigas suggestive of functionally relevant promoter DNA methylation in invertebrates. Front Physiol (2014) 0.87
Dietary alleviation of maternal obesity and diabetes: increased resistance to diet-induced obesity transcriptional and epigenetic signatures. PLoS One (2013) 0.85
The Role of Endocrine Disruptors in the Epigenetics of Reproductive Disease and Dysfunction: Potential Relevance to Humans. Curr Obstet Gynecol Rep (2012) 0.79
Perinatal nutritional programming of health and metabolic adult disease. World J Diabetes (2011) 0.77
GCN2 in the brain programs PPARγ2 and triglyceride storage in the liver during perinatal development in response to maternal dietary fat. PLoS One (2013) 0.76
Embryonic environment and transgenerational effects in quail. Genet Sel Evol (2017) 0.75
Exposure to the environmental endocrine disruptor TCDD and human reproductive dysfunction: Translating lessons from murine models. Reprod Toxicol (2016) 0.75
Prenatal Exposure to a Maternal High-Fat Diet Affects Histone Modification of Cardiometabolic Genes in Newborn Rats. Nutrients (2017) 0.75
DNA methylation in spermatogenesis and male infertility. Exp Ther Med (2016) 0.75
Development, brain plasticity and reward: early high-fat diet exposure confers vulnerability to obesity-view from the chair. Int J Obes Suppl (2012) 0.75
The placental gateway of maternal transgenerational epigenetic inheritance. J Genet (2017) 0.75
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature (2007) 65.18
Chromatin modifications and their function. Cell (2007) 55.98
A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell (2006) 48.80
Human DNA methylomes at base resolution show widespread epigenomic differences. Nature (2009) 34.27
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science (2009) 32.97
Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature (2008) 30.29
Control of developmental regulators by Polycomb in human embryonic stem cells. Cell (2006) 28.21
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat Genet (2007) 20.22
The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores. Nat Genet (2009) 18.90
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science (2009) 18.82
Dissecting direct reprogramming through integrative genomic analysis. Nature (2008) 16.47
Chromatin signatures of pluripotent cell lines. Nat Cell Biol (2006) 12.88
Linking DNA methylation and histone modification: patterns and paradigms. Nat Rev Genet (2009) 12.08
Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells. Nat Biotechnol (2009) 11.18
Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains. PLoS Genet (2008) 11.17
Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts. Nat Genet (2009) 10.54
Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nat Neurosci (2009) 10.17
Comprehensive high-throughput arrays for relative methylation (CHARM). Genome Res (2008) 8.62
Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a. Proc Natl Acad Sci U S A (2000) 8.12
Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors. Mol Cell (2008) 7.68
Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming. Nat Biotechnol (2009) 7.59
Tissue-specific expression and regulation of sexually dimorphic genes in mice. Genome Res (2006) 6.45
Gene body-specific methylation on the active X chromosome. Science (2007) 6.33
Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation. Cell Stem Cell (2008) 5.40
New nomenclature for chromatin-modifying enzymes. Cell (2007) 5.34
Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring. J Nutr (2005) 4.57
CpG islands--'a rough guide'. FEBS Lett (2009) 4.55
Epigenetic inheritance during the cell cycle. Nat Rev Mol Cell Biol (2009) 4.43
DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific. Hum Mol Genet (2009) 4.25
DNA methylation and histone modifications: teaming up to silence genes. Curr Opin Genet Dev (2005) 4.25
Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia. J Exp Med (2008) 4.25
Developmental programming of CpG island methylation profiles in the human genome. Nat Struct Mol Biol (2009) 3.96
Genomic patterns of DNA methylation: targets and function of an epigenetic mark. Curr Opin Cell Biol (2007) 3.54
The Foxa family of transcription factors in development and metabolism. Cell Mol Life Sci (2006) 3.47
DNA methylation, insulin resistance, and blood pressure in offspring determined by maternal periconceptional B vitamin and methionine status. Proc Natl Acad Sci U S A (2007) 3.24
H3K27me3 forms BLOCs over silent genes and intergenic regions and specifies a histone banding pattern on a mouse autosomal chromosome. Genome Res (2008) 3.09
Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1. J Clin Invest (2008) 3.02
Fetal programming of coronary heart disease. Trends Endocrinol Metab (2002) 3.00
Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression. Proc Natl Acad Sci U S A (2009) 2.98
Maternal undernutrition during the preimplantation period of rat development causes blastocyst abnormalities and programming of postnatal hypertension. Development (2000) 2.82
Stem cell regulation by polycomb repressors: postponing commitment. Curr Opin Cell Biol (2008) 2.81
Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density. Cell Metab (2009) 2.76
Ten putative contributors to the obesity epidemic. Crit Rev Food Sci Nutr (2009) 2.71
Feeding pregnant rats a protein-restricted diet persistently alters the methylation of specific cytosines in the hepatic PPAR alpha promoter of the offspring. Br J Nutr (2008) 2.55
X-inactivation in female human embryonic stem cells is in a nonrandom pattern and prone to epigenetic alterations. Proc Natl Acad Sci U S A (2008) 2.53
The epigenetic magic of histone lysine methylation. FEBS J (2006) 2.52
Sex differences in the expression of hepatic drug metabolizing enzymes. Mol Pharmacol (2009) 2.45
Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia. Genes Dev (2008) 2.41
Growth hormone regulation of sex-dependent liver gene expression. Mol Endocrinol (2006) 2.37
Towards a new developmental synthesis: adaptive developmental plasticity and human disease. Lancet (2009) 2.35
Role of Jhdm2a in regulating metabolic gene expression and obesity resistance. Nature (2009) 2.35
Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail. Diabetes (2009) 2.34
Epigenetic histone H3 lysine 9 methylation in metabolic memory and inflammatory phenotype of vascular smooth muscle cells in diabetes. Proc Natl Acad Sci U S A (2008) 2.33
Gene expression patterns in human placenta. Proc Natl Acad Sci U S A (2006) 2.33
Periconceptional maternal folic acid use of 400 microg per day is related to increased methylation of the IGF2 gene in the very young child. PLoS One (2009) 2.23
Review: Sex and the human placenta: mediating differential strategies of fetal growth and survival. Placenta (2009) 2.17
Sex-dependent liver gene expression is extensive and largely dependent upon signal transducer and activator of transcription 5b (STAT5b): STAT5b-dependent activation of male genes and repression of female genes revealed by microarray analysis. Mol Endocrinol (2006) 2.17
Developmental origins of disease and determinants of chromatin structure: maternal diet modifies the primate fetal epigenome. J Mol Endocrinol (2008) 2.15
DNA methylation and gene expression differences in children conceived in vitro or in vivo. Hum Mol Genet (2009) 1.92
Maternal programming of steroid receptor expression and phenotype through DNA methylation in the rat. Front Neuroendocrinol (2005) 1.87
Mechanisms of transcriptional repression by histone lysine methylation. Int J Dev Biol (2009) 1.82
The epigenome: archive of the prenatal environment. Epigenetics (2009) 1.82
The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing. Genes Dev (2009) 1.82
Brain renin-angiotensin system: fetal epigenetic programming by maternal protein restriction during pregnancy. Reprod Sci (2009) 1.79
Hypothalamic proopiomelanocortin promoter methylation becomes altered by early overfeeding: an epigenetic model of obesity and the metabolic syndrome. J Physiol (2009) 1.74
Long-term effect of in vitro culture of mouse embryos with serum on mRNA expression of imprinting genes, development, and behavior. Proc Natl Acad Sci U S A (2004) 1.74
Sexual dimorphism in environmental epigenetic programming. Mol Cell Endocrinol (2009) 1.74
Complex disease, gender and epigenetics. Ann Med (2006) 1.73
Sex of the cell dictates its response: differential gene expression and sensitivity to cell death inducing stress in male and female cells. FASEB J (2009) 1.62
Folic acid supplementation during the juvenile-pubertal period in rats modifies the phenotype and epigenotype induced by prenatal nutrition. J Nutr (2009) 1.61
Contrasting effects of different maternal diets on sexually dimorphic gene expression in the murine placenta. Proc Natl Acad Sci U S A (2010) 1.58
Long-term effects of culture of preimplantation mouse embryos on behavior. Proc Natl Acad Sci U S A (2004) 1.57
Sex determines the expression level of one third of the actively expressed genes in bovine blastocysts. Proc Natl Acad Sci U S A (2010) 1.46
Sexually dimorphic P450 gene expression in liver-specific hepatocyte nuclear factor 4alpha-deficient mice. Mol Endocrinol (2004) 1.46
Epigenetic mechanisms in the development of type 2 diabetes. Trends Endocrinol Metab (2009) 1.46
Histone code modifications repress glucose transporter 4 expression in the intrauterine growth-restricted offspring. J Biol Chem (2008) 1.44
Epigenetics: intrauterine growth retardation (IUGR) modifies the histone code along the rat hepatic IGF-1 gene. FASEB J (2009) 1.41
Sex differences in histone modifications in the neonatal mouse brain. Epigenetics (2009) 1.40
The embryo and its future. Biol Reprod (2004) 1.39
Bivalent domains enforce transcriptional memory of DNA methylated genes in cancer cells. Proc Natl Acad Sci U S A (2008) 1.36
Exercise-induced histone modifications in human skeletal muscle. J Physiol (2009) 1.36
Obesity and metabolic syndrome in histone demethylase JHDM2a-deficient mice. Genes Cells (2009) 1.28
Nutritional programming affects hypothalamic organization and early response to leptin. Endocrinology (2009) 1.27
Adaptive responses by mouse early embryos to maternal diet protect fetal growth but predispose to adult onset disease. Biol Reprod (2007) 1.25
Gender-specific programming of insulin secretion and action. J Endocrinol (2002) 1.22
Pharmacological inhibition of DNA methylation induces proinvasive and prometastatic genes in vitro and in vivo. Neoplasia (2008) 1.20
The liver X-receptor gene promoter is hypermethylated in a mouse model of prenatal protein restriction. Am J Physiol Regul Integr Comp Physiol (2009) 1.18
Lamb birth weight is affected by culture system utilized during in vitro pre-elongation development of ovine embryos. Biol Reprod (1995) 1.18
Imprinted gene expression in the rat embryo-fetal axis is altered in response to periconceptional maternal low protein diet. Reproduction (2006) 1.17
Regional-specific global cytosine methylation and DNA methyltransferase expression in the adult rat hippocampus. Neurosci Lett (2008) 1.17
Fetal growth and the physiological control of glucose tolerance in adults: a minimal model analysis. Am J Physiol Endocrinol Metab (2000) 1.16
The effects of pH on DNA methylation state: In vitro and post-mortem brain studies. J Neurosci Methods (2008) 1.15
Epigenomic profiling indicates a role for DNA methylation in early postnatal liver development. Hum Mol Genet (2009) 1.13
Plasma growth hormone pulse activation of hepatic JAK-STAT5 signaling: developmental regulation and role in male-specific liver gene expression. Endocrinology (2000) 1.10
Methods of DNA methylation analysis. Curr Opin Clin Nutr Metab Care (2007) 1.10
The regulator of sex-limitation gene, rsl, enforces male-specific liver gene expression by negative regulation. Endocrinology (2003) 1.08
Inheritance of an epigenetic mark: the CpG DNA methyltransferase 1 is required for de novo establishment of a complex pattern of non-CpG methylation. PLoS One (2007) 1.07
Maternal hyperinsulinemia predisposes rat fetuses for hyperinsulinemia, and adult-onset obesity and maternal mild food restriction reverses this phenotype. Am J Physiol Endocrinol Metab (2005) 1.07
Growth hormone, but not prolactin, maintains, low-level activation of STAT5a and STAT5b in female rat liver. Endocrinology (1999) 1.07
Mutations in PCSK9 cause autosomal dominant hypercholesterolemia. Nat Genet (2003) 11.67
Heterozygous TGFBR2 mutations in Marfan syndrome. Nat Genet (2004) 6.15
Update of the UMD-FBN1 mutation database and creation of an FBN1 polymorphism database. Hum Mutat (2003) 2.10
CTG repeat instability and size variation timing in DNA repair-deficient mice. EMBO J (2003) 1.96
Sexual dimorphism in environmental epigenetic programming. Mol Cell Endocrinol (2009) 1.74
Mutations and polymorphisms in the proprotein convertase subtilisin kexin 9 (PCSK9) gene in cholesterol metabolism and disease. Hum Mutat (2009) 1.67
Placental contribution to the origins of sexual dimorphism in health and diseases: sex chromosomes and epigenetics. Biol Sex Differ (2013) 1.60
C57BL/6J and A/J mice fed a high-fat diet delineate components of metabolic syndrome. Obesity (Silver Spring) (2007) 1.58
Msh3 is a limiting factor in the formation of intergenerational CTG expansions in DM1 transgenic mice. Hum Genet (2006) 1.55
Novel mutations of the PCSK9 gene cause variable phenotype of autosomal dominant hypercholesterolemia. Hum Mutat (2005) 1.54
Nutritional epigenomics of metabolic syndrome: new perspective against the epidemic. Diabetes (2005) 1.48
CTG trinucleotide repeat "big jumps": large expansions, small mice. PLoS Genet (2007) 1.46
Sex- and diet-specific changes of imprinted gene expression and DNA methylation in mouse placenta under a high-fat diet. PLoS One (2010) 1.41
Maternal diets trigger sex-specific divergent trajectories of gene expression and epigenetic systems in mouse placenta. PLoS One (2012) 1.32
MSH2-dependent germinal CTG repeat expansions are produced continuously in spermatogonia from DM1 transgenic mice. Mol Cell Biol (2004) 1.30
The case for strategic international alliances to harness nutritional genomics for public and personal health. Br J Nutr (2005) 1.24
Developmental programming and epigenetics. Am J Clin Nutr (2011) 1.18
Identification of 23 TGFBR2 and 6 TGFBR1 gene mutations and genotype-phenotype investigations in 457 patients with Marfan syndrome type I and II, Loeys-Dietz syndrome and related disorders. Hum Mutat (2008) 1.14
Genotype-phenotype correlation in von Hippel-Lindau families with renal lesions. Hum Mutat (2004) 1.13
Heterogeneity of persistent hyperinsulinaemic hypoglycaemia. A series of 175 cases. Eur J Pediatr (2002) 1.10
The UMD-LDLR database: additions to the software and 490 new entries to the database. Hum Mutat (2002) 1.07
The focal form of persistent hyperinsulinemic hypoglycemia of infancy: morphological and molecular studies show structural and functional differences with insulinoma. Diabetes (2003) 1.06
Resistance to high-fat diet in the female progeny of obese mice fed a control diet during the periconceptual, gestation, and lactation periods. Am J Physiol Endocrinol Metab (2006) 1.02
Metabolic imprinting, programming and epigenetics - a review of present priorities and future opportunities. Br J Nutr (2010) 1.02
The molecular basis of familial hypercholesterolemia in Lebanon: spectrum of LDLR mutations and role of PCSK9 as a modifier gene. Hum Mutat (2009) 0.99
ABCC8 (SUR1) and KCNJ11 (KIR6.2) mutations in persistent hyperinsulinemic hypoglycemia of infancy and evaluation of different therapeutic measures. J Pediatr Endocrinol Metab (2002) 0.98
DM1 CTG expansions affect insulin receptor isoforms expression in various tissues of transgenic mice. Biochim Biophys Acta (2007) 0.97
Molecular spectrum of autosomal dominant hypercholesterolemia in France. Hum Mutat (2010) 0.95
Implication of the folate-methionine metabolism pathways in susceptibility to follicular lymphomas. Blood (2006) 0.94
Early nutrition and epigenetic programming: chasing shadows. Curr Opin Clin Nutr Metab Care (2010) 0.92
Facial appearance in persistent hyperinsulinemic hypoglycemia. Am J Med Genet (2002) 0.92
Nutri-epigenomics: lifelong remodelling of our epigenomes by nutritional and metabolic factors and beyond. Clin Chem Lab Med (2007) 0.91
A fourth locus for autosomal dominant hypercholesterolemia maps at 16q22.1. Eur J Hum Genet (2010) 0.91
Sexual dimorphism in non-Mendelian inheritance. Pediatr Res (2008) 0.90
Frequent overexpression of cyclin D2/cyclin-dependent kinase 4 in Wilms' tumor. Cancer Lett (2005) 0.88
Changes in WT1 splicing are associated with a specific gene expression profile in Wilms' tumour. Oncogene (2002) 0.88
Genetics of congenital hyperinsulinism. Endocr Pathol (2004) 0.86
Dietary alleviation of maternal obesity and diabetes: increased resistance to diet-induced obesity transcriptional and epigenetic signatures. PLoS One (2013) 0.85
A simple and fast method for cell recovery and DNA content analysis from various mouse tissues by flow cytometry. Cytotechnology (2006) 0.84
Lifelong circadian and epigenetic drifts in metabolic syndrome. Epigenetics (2007) 0.83
Epigenetic control of development and expression of quantitative traits. Reprod Fertil Dev (2011) 0.82
Maternal calorie restriction modulates placental mitochondrial biogenesis and bioenergetic efficiency: putative involvement in fetoplacental growth defects in rats. Am J Physiol Endocrinol Metab (2012) 0.80
Third Santorini conference pharmacogenomics workshop report: "Pharmacogenomics at the crossroads: what else than good science will be needed for the field to become part of Personalized Medicine?". Clin Chem Lab Med (2007) 0.78
The genetics of neonatal hyperinsulinism. Horm Res (2003) 0.78
Cadherins in Wilms' tumor: E-cadherin expression despite absence of WT1. Anticancer Res (2003) 0.77
Analysis of CTG repeats using DM1 model mice. Methods Mol Biol (2004) 0.77
Hyperinsulinemic hypoglycemia in children. Ann Endocrinol (Paris) (2004) 0.76
Reply to "The question of heterogeneity in Marfan syndrome" Nat Genet (1995) 0.75
Delineation of a 2.8 megabases region harboring a potential tumor suppressor gene involved in renal cell carcinoma, that is commonly deleted from chromosome 14. Anticancer Res (2004) 0.75
[Sexual dimorphism in the XXI(st) century]. Med Sci (Paris) (2012) 0.75
[BDNF in feto-placental development]. Med Sci (Paris) (2011) 0.75