Published in AIDS on June 01, 1990
Mutational inactivation of an inhibitory sequence in human immunodeficiency virus type 1 results in Rev-independent gag expression. J Virol (1992) 3.14
The Rev protein of human immunodeficiency virus type 1 promotes polysomal association and translation of gag/pol and vpu/env mRNAs. Mol Cell Biol (1992) 2.83
Human immunodeficiency virus type 1 gag-pol frameshifting is dependent on downstream mRNA secondary structure: demonstration by expression in vivo. J Virol (1992) 2.49
Sequence-specific interaction of Tat protein and Tat peptides with the transactivation-responsive sequence element of human immunodeficiency virus type 1 in vitro. Proc Natl Acad Sci U S A (1990) 2.32
Role of the hepatitis B virus posttranscriptional regulatory element in export of intronless transcripts. Mol Cell Biol (1995) 1.95
Identification of a Rev-related protein by analysis of spliced transcripts of the human endogenous retroviruses HTDV/HERV-K. J Virol (1995) 1.91
Different sites of interaction for Rev, Tev, and Rex proteins within the Rev-responsive element of human immunodeficiency virus type 1. J Virol (1990) 1.90
The human immunodeficiency virus type 1 long terminal repeat specifies two different transcription complexes, only one of which is regulated by Tat. J Virol (1993) 1.67
The human immunodeficiency virus type 1 Rev protein shuttles between the cytoplasm and nuclear compartments. Mol Cell Biol (1994) 1.67
Hepatitis B virus RNA element that facilitates accumulation of surface gene transcripts in the cytoplasm. J Virol (1994) 1.66
Mechanism of translation of monocistronic and multicistronic human immunodeficiency virus type 1 mRNAs. Mol Cell Biol (1992) 1.61
Cellular protein modulates effects of human immunodeficiency virus type 1 Rev. J Virol (1994) 1.56
Critical chemical features in trans-acting-responsive RNA are required for interaction with human immunodeficiency virus type 1 Tat protein. J Virol (1991) 1.45
Dominant negative mutants of human T-cell leukemia virus type I Rex and human immunodeficiency virus type 1 Rev fail to multimerize in vivo. J Virol (1993) 1.45
The Rev protein of human immunodeficiency virus type 1 counteracts the effect of an AU-rich negative element in the human papillomavirus type 1 late 3' untranslated region. J Virol (1995) 1.40
Identification of the Rev transactivation and Rev-responsive elements of feline immunodeficiency virus. J Virol (1992) 1.38
Inhibition of HIV-LTR gene expression by oligonucleotides targeted to the TAR element. Nucleic Acids Res (1991) 1.37
The blocks to human immunodeficiency virus type 1 Tat and Rev functions in mouse cell lines are independent. J Virol (1993) 1.34
Analysis of trans-acting response decoy RNA-mediated inhibition of human immunodeficiency virus type 1 transactivation. J Virol (1991) 1.34
The number of positively charged amino acids in the basic domain of Tat is critical for trans-activation and complex formation with TAR RNA. Proc Natl Acad Sci U S A (1991) 1.32
The Rex regulatory protein of human T-cell lymphotropic virus type I binds specifically to its target site within the viral RNA. Proc Natl Acad Sci U S A (1991) 1.26
Functional analysis of interactions between Tat and the trans-activation response element of human immunodeficiency virus type 1 in cells. J Virol (1993) 1.24
Restriction of human immunodeficiency virus type 1 production in a human astrocytoma cell line is associated with a cellular block in Rev function. J Virol (1995) 1.23
Inhibition of human immunodeficiency virus type 1 in human T cells by a potent Rev response element decoy consisting of the 13-nucleotide minimal Rev-binding domain. J Virol (1994) 1.22
Casein kinase II is a selective target of HIV-1 transcriptional inhibitors. Proc Natl Acad Sci U S A (1997) 1.12
Repression in vitro, by human adenovirus E1A protein domains, of basal or Tat-activated transcription of the human immunodeficiency virus type 1 long terminal repeat. J Virol (1995) 1.00
Epitopes of human immunodeficiency virus regulatory proteins tat, nef, and rev are expressed in normal human tissue. Am J Pathol (1992) 0.98
Rapid activation and subsequent down-regulation of the human immunodeficiency virus type 1 promoter in the presence of Tat: possible mechanisms contributing to latency. J Virol (1991) 0.97
Identification and characterization of the bovine immunodeficiency-like virus tat gene. J Virol (1992) 0.97
Fluorescent HIV-1 Dimerization Initiation Site: design, properties, and use for ligand discovery. J Am Chem Soc (2007) 0.92
Human immunodeficiency virus type 1 Tat does not transactivate mature trans-acting responsive region RNA species in the nucleus or cytoplasm of primate cells. J Virol (1991) 0.89
Aptamer-based therapeutics: new approaches to combat human viral diseases. Pharmaceuticals (Basel) (2013) 0.86
Rev of human immunodeficiency virus and Rex of the human T-cell leukemia virus type I can counteract an mRNA downregulatory element of the transferrin receptor mRNA. Nucleic Acids Res (1994) 0.86
Antiretroviral therapy: strategies beyond single-agent reverse transcriptase inhibition. Antimicrob Agents Chemother (1992) 0.85
Using an emissive uridine analogue for assembling fluorescent HIV-1 TAR constructs. Tetrahedron (2007) 0.85
Inhibition by interferon of herpes simplex virus type 1-activated transcription of tat-defective provirus. Proc Natl Acad Sci U S A (1991) 0.84
TAR-RNA binding by HIV-1 Tat protein is selectively inhibited by its L-enantiomer. Nucleic Acids Res (1998) 0.84
A multifunctional expression vector for an anti-HIV-1 ribozyme that produces a 5'- and 3'-trimmed trans-acting ribozyme, targeted against HIV-1 RNA, and cis-acting ribozymes that are designed to bind to and thereby sequester trans-activator proteins such as Tat and Rev. Nucleic Acids Res (1994) 0.83
Human immunodeficiency virus type 1 Rev-responsive element RNA binds to host cell-specific proteins. J Virol (1994) 0.82
Rotational symmetry in ribonucleotide strand requirements for binding of HIV-1 Tat protein to TAR RNA. Nucleic Acids Res (1993) 0.80
Human immunodeficiency virus Tat transactivation: induction of a tissue-specific enhancer in a nonpermissive cell line. J Virol (1991) 0.79
rev protein of human immunodeficiency virus type 1 affects the stability and transport of the viral mRNA. Proc Natl Acad Sci U S A (1989) 8.76
The pX protein of HTLV-I is a transcriptional activator of its long terminal repeats. Science (1985) 6.60
Cloning and functional analysis of multiply spliced mRNA species of human immunodeficiency virus type 1. J Virol (1990) 5.64
Expression and characterization of the trans-activator of HTLV-III/LAV virus. Science (1986) 5.15
The rev (trs/art) protein of human immunodeficiency virus type 1 affects viral mRNA and protein expression via a cis-acting sequence in the env region. J Virol (1989) 5.07
Distinct RNA sequences in the gag region of human immunodeficiency virus type 1 decrease RNA stability and inhibit expression in the absence of Rev protein. J Virol (1992) 3.44
Env and Vpu proteins of human immunodeficiency virus type 1 are produced from multiple bicistronic mRNAs. J Virol (1990) 3.42
Inactivation of the human immunodeficiency virus type 1 inhibitory elements allows Rev-independent expression of Gag and Gag/protease and particle formation. J Virol (1997) 3.28
Sequence and secondary structure of Drosophila melanogaster 5.8S and 2S rRNAs and of the processing site between them. Nucleic Acids Res (1979) 3.15
Mutational inactivation of an inhibitory sequence in human immunodeficiency virus type 1 results in Rev-independent gag expression. J Virol (1992) 3.14
Cis-acting sequences responsible for the transcriptional activation of human T-cell leukemia virus type I constitute a conditional enhancer. Proc Natl Acad Sci U S A (1986) 3.12
Regulation of a metallothionein-growth hormone hybrid gene in bovine papilloma virus. Proc Natl Acad Sci U S A (1983) 3.06
A quantitative bioassay for HIV-1 based on trans-activation. Science (1988) 2.99
The Rev protein of human immunodeficiency virus type 1 promotes polysomal association and translation of gag/pol and vpu/env mRNAs. Mol Cell Biol (1992) 2.83
The structural basis for spectral variations in green fluorescent protein. Nat Struct Biol (1997) 2.79
Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation. EMBO J (1997) 2.57
Improved DNA: liposome complexes for increased systemic delivery and gene expression. Nat Biotechnol (1997) 2.52
Complex splicing in the human T-cell leukemia virus (HTLV) family of retroviruses: novel mRNAs and proteins produced by HTLV type I. J Virol (1992) 2.52
Expression of human immunodeficiency virus type 1 vif and vpr mRNAs is Rev-dependent and regulated by splicing. Virology (1991) 2.43
The human poly(A)-binding protein 1 shuttles between the nucleus and the cytoplasm. J Biol Chem (1998) 2.23
Feedback regulation of human immunodeficiency virus type 1 expression by the Rev protein. J Virol (1990) 2.17
Identification of trans-dominant HIV-1 rev protein mutants by direct transfer of bacterially produced proteins into human cells. Nucleic Acids Res (1990) 2.14
Different sites of interaction for Rev, Tev, and Rex proteins within the Rev-responsive element of human immunodeficiency virus type 1. J Virol (1990) 1.90
Elements distinct from human immunodeficiency virus type 1 splice sites are responsible for the Rev dependence of env mRNA. J Virol (1994) 1.88
A novel human immunodeficiency virus type 1 protein, tev, shares sequences with tat, env, and rev proteins. J Virol (1990) 1.87
The posttranscriptional control element of the simian retrovirus type 1 forms an extensive RNA secondary structure necessary for its function. J Virol (1996) 1.85
The inducibly expressed GTPase localizes to the endoplasmic reticulum, independently of GTP binding. J Biol Chem (1997) 1.75
A bioassay for HIV-1 based on Env-CD4 interaction. AIDS Res Hum Retroviruses (1990) 1.70
Development and applications of enhanced green fluorescent protein mutants. Biotechniques (1998) 1.68
Cross-activation of the Rex proteins of HTLV-I and BLV and of the Rev protein of HIV-1 and nonreciprocal interactions with their RNA responsive elements. New Biol (1989) 1.66
Mechanism of translation of monocistronic and multicistronic human immunodeficiency virus type 1 mRNAs. Mol Cell Biol (1992) 1.61
Identification and characterization of SET, a nuclear phosphoprotein encoded by the translocation break point in acute undifferentiated leukemia. J Biol Chem (1994) 1.57
Intracellular trafficking and interactions of the HIV-1 Tat protein. Virology (1998) 1.57
Rapidly and slowly replicating human immunodeficiency virus type 1 isolates can be distinguished according to target-cell tropism in T-cell and monocyte cell lines. Proc Natl Acad Sci U S A (1989) 1.51
The HIV-1 virion-associated protein vpr is a coactivator of the human glucocorticoid receptor. J Exp Med (1999) 1.43
Evaluation of novel human immunodeficiency virus type 1 Gag DNA vaccines for protein expression in mammalian cells and induction of immune responses. J Virol (1999) 1.43
Expression of two human growth hormone genes in monkey cells infected by simian virus 40 recombinants. Proc Natl Acad Sci U S A (1981) 1.39
Binding of trans-dominant mutant Rev protein of human immunodeficiency virus type 1 to the cis-acting Rev-responsive element does not affect the fate of viral mRNA. New Biol (1990) 1.37
Preferential binding of poly(A)-binding protein 1 to an inhibitory RNA element in the human immunodeficiency virus type 1 gag mRNA. J Biol Chem (1997) 1.35
Dual effect of interleukin 4 on HIV-1 expression: implications for viral phenotypic switch and disease progression. Proc Natl Acad Sci U S A (1998) 1.32
Transcription-dependent nuclear-cytoplasmic trafficking is required for the function of the von Hippel-Lindau tumor suppressor protein. Mol Cell Biol (1999) 1.30
Molecular biology of HIV-1: positive and negative regulatory elements important for virus expression. AIDS (1993) 1.27
The Rex regulatory protein of human T-cell lymphotropic virus type I binds specifically to its target site within the viral RNA. Proc Natl Acad Sci U S A (1991) 1.26
Visualization of G protein-coupled receptor trafficking with the aid of the green fluorescent protein. Endocytosis and recycling of cholecystokinin receptor type A. J Biol Chem (1997) 1.23
Restriction of human immunodeficiency virus type 1 production in a human astrocytoma cell line is associated with a cellular block in Rev function. J Virol (1995) 1.23
Splicing variability in HIV type 1 revealed by quantitative RNA polymerase chain reaction. AIDS Res Hum Retroviruses (1994) 1.20
Potentiation of simian immunodeficiency virus (SIV)-specific CD4(+) and CD8(+) T cell responses by a DNA-SIV and NYVAC-SIV prime/boost regimen. J Immunol (2001) 1.19
Intracellular trafficking of the human immunodeficiency virus type 1 Rev protein: involvement of continued rRNA synthesis in nuclear retention. AIDS Res Hum Retroviruses (1995) 1.19
NIH conference. Antiretroviral therapy in AIDS. Ann Intern Med (1990) 1.15
Pathologic human GR mutant has a transdominant negative effect on the wild-type GR by inhibiting its translocation into the nucleus: importance of the ligand-binding domain for intracellular GR trafficking. J Clin Endocrinol Metab (2001) 1.13
Menkes' disease: abnormal metallothionein gene regulation in response to copper. Cell (1985) 1.08
CD4+ T-cell loss and delayed expression of modulators of immune responses at mucosal sites of vaccinated macaques following SIV(mac251) infection. Mucosal Immunol (2008) 1.07
Activation of tat-defective human immunodeficiency virus by ultraviolet light. New Biol (1990) 1.06
HHR23A, the human homologue of the yeast repair protein RAD23, interacts specifically with Vpr protein and prevents cell cycle arrest but not the transcriptional effects of Vpr. Virology (1998) 1.03
Analysis of intracellular trafficking and interactions of cytoplasmic HIV-1 Rev mutants in living cells. Virology (1998) 1.02
Identification of a novel posttranscriptional regulatory element by using a rev- and RRE-mutated human immunodeficiency virus type 1 DNA proviral clone as a molecular trap. J Virol (2001) 1.02
Conservative mutations in the putative metal-binding region of human immunodeficiency virus tat disrupt virus replication. AIDS Res Hum Retroviruses (1990) 1.02
Analysis of human immunodeficiency virus type 1 mRNA splicing patterns during disease progression in peripheral blood mononuclear cells from infected individuals. AIDS Res Hum Retroviruses (1996) 1.00
Decreased human immunodeficiency virus type 1 plasma viremia during antiretroviral therapy reflects downregulation of viral replication in lymphoid tissue. Proc Natl Acad Sci U S A (1995) 0.99
Identification of in vivo phosphorylation sites of SET, a nuclear phosphoprotein encoded by the translocation breakpoint in acute undifferentiated leukemia. FEBS Lett (1994) 0.98
Rapid activation and subsequent down-regulation of the human immunodeficiency virus type 1 promoter in the presence of Tat: possible mechanisms contributing to latency. J Virol (1991) 0.97
Nucleocytoplasmic transport in human astrocytes: decreased nuclear uptake of the HIV Rev shuttle protein. J Cell Sci (2001) 0.91
Retracted Inhibition of Rev-mediated HIV-1 expression by an RNA binding protein encoded by the interferon-inducible 9-27 gene. Science (1993) 0.90
Macaques co-immunized with SIVgag/pol-HIVenv and IL-12 plasmid have increased cellular responses. J Med Primatol (2007) 0.90
CXCR4 mediates entry and productive infection of syncytia-inducing (X4) HIV-1 strains in primary macrophages. Virology (2000) 0.90
CCAAT-enhancer-binding protein beta (C/EBP beta) activates CCR5 promoter: increased C/EBP beta and CCR5 in T lymphocytes from HIV-1-infected individuals. J Immunol (2001) 0.90
Identification of the caprine arthritis encephalitis virus Rev protein and its cis-acting Rev-responsive element. Virology (1994) 0.89
Antiretroviral monotherapy in early stage human immunodeficiency virus disease has no detectable effect on virus load in peripheral blood and lymph nodes. J Infect Dis (1996) 0.88
Reduced viral load and lack of CD4 depletion in SCID-hu mice infected with Rev-independent clones of human immunodeficiency virus type 1. J Virol (1997) 0.87
Unusual CD4+CD8+ phenotype in a greek patient diagnosed with adult T-cell leukemia positive for human T-cell leukemia virus type I (HTLV-I). Leuk Res (2000) 0.86
Expression of cloned growth hormone and metallothionein genes in heterologous cells. Recent Prog Horm Res (1983) 0.85
Sulfonic acid dyes: inhibition of the human immunodeficiency virus and mechanism of action. J Acquir Immune Defic Syndr (1992) 0.85
Inflammatory polyarthropathy and bone remodeling in HTLV-I Tax-transgenic mice. J Acquir Immune Defic Syndr Hum Retrovirol (1997) 0.82
Inhibitory activity of the equine infectious anemia virus major 5' splice site in the absence of Rev. J Virol (1996) 0.82
Expression of human immunodeficiency virus long terminal repeat in the human promonocyte cell line U937: effect of endotoxin and cytokines. Cell Immunol (1990) 0.79
Molecular characterization of a recombinant HIV type 1 isolate (A/G/E/?): unidentified regions may be derived from parental subtype E sequences. AIDS Res Hum Retroviruses (2000) 0.79
Properties of human growth hormone polypeptides: purified from pituitary extracts and synthesized in monkey kidney cells and bacteria. J Clin Endocrinol Metab (1982) 0.78
Tat and Rev: positive regulators of HIV gene expression. AIDS (1990) 0.76
HIV: molecular mechanisms. Mol Med Today (1995) 0.75
Inhibition of Rev-mediated HIV-1 expression. Science (1994) 0.75