Published in Free Radic Biol Med on October 06, 2011
Cell signaling and mitochondrial dynamics: Implications for neuronal function and neurodegenerative disease. Neurobiol Dis (2012) 1.05
Nitric oxide plays a role in stem cell niche homeostasis through its interaction with auxin. Plant Physiol (2014) 0.83
Curcumin induces differentiation of embryonic stem cells through possible modulation of nitric oxide-cyclic GMP pathway. Protein Cell (2012) 0.82
Role of nitric oxide in the maintenance of pluripotency and regulation of the hypoxia response in stem cells. World J Stem Cells (2015) 0.81
Slow and sustained nitric oxide releasing compounds inhibit multipotent vascular stem cell proliferation and differentiation without causing cell death. Biochem Biophys Res Commun (2014) 0.79
Divergent modulation of normal and neoplastic stem cells by thrombospondin-1 and CD47 signaling. Int J Biochem Cell Biol (2016) 0.76
Regulation of mitochondrial function and endoplasmic reticulum stress by nitric oxide in pluripotent stem cells. World J Stem Cells (2017) 0.75
Sodium Nitroprusside Changed The Metabolism of Mesenchymal Stem Cells to An Anaerobic State while Viability and Proliferation Remained Intact. Cell J (2016) 0.75
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell (2006) 120.51
Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell (2007) 101.42
Induced pluripotent stem cell lines derived from human somatic cells. Science (2007) 71.50
Embryonic stem cell lines derived from human blastocysts. Science (1998) 65.53
Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev (1991) 42.38
Generation of germline-competent induced pluripotent stem cells. Nature (2007) 32.77
Reprogramming of human somatic cells to pluripotency with defined factors. Nature (2007) 30.84
In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature (2007) 28.24
Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell (2007) 21.58
Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. Am J Physiol (1996) 13.14
Generation of human induced pluripotent stem cells from dermal fibroblasts. Proc Natl Acad Sci U S A (2008) 13.09
Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts. Nat Genet (2009) 10.54
Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2. Nat Biotechnol (2008) 10.29
Little evidence for developmental plasticity of adult hematopoietic stem cells. Science (2002) 9.63
Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages. Nature (2005) 9.44
Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. Cell Stem Cell (2009) 8.62
Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming. Nat Biotechnol (2009) 7.59
Functional cardiomyocytes derived from human induced pluripotent stem cells. Circ Res (2009) 7.09
Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells. Nat Med (2003) 6.09
Guanylyl cyclases and signaling by cyclic GMP. Pharmacol Rev (2000) 4.10
Sildenafil: an orally active type 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction. Int J Impot Res (1996) 3.85
Directed and systematic differentiation of cardiovascular cells from mouse induced pluripotent stem cells. Circulation (2008) 3.11
Human embryonic stem cell-derived cardiomyocytes survive and mature in the mouse heart and transiently improve function after myocardial infarction. Stem Cell Res (2007) 3.04
NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential. Nat Rev Drug Discov (2006) 2.84
Regulation of myosin phosphatase by a specific interaction with cGMP- dependent protein kinase Ialpha. Science (1999) 2.84
Nitric oxide synthase is a cytochrome P-450 type hemoprotein. Biochemistry (1992) 2.65
Function of cGMP-dependent protein kinases as revealed by gene deletion. Physiol Rev (2006) 2.63
Stem cell differentiation requires a paracrine pathway in the heart. FASEB J (2002) 2.55
Shattuck Lecture. Nitric oxide and cyclic GMP in cell signaling and drug development. N Engl J Med (2006) 2.53
Selective loss of cone function in mice lacking the cyclic nucleotide-gated channel CNG3. Proc Natl Acad Sci U S A (1999) 2.46
Skeletal muscle stem cells do not transdifferentiate into cardiomyocytes after cardiac grafting. J Mol Cell Cardiol (2002) 2.29
Cardiomyocyte-specific overexpression of nitric oxide synthase 3 improves left ventricular performance and reduces compensatory hypertrophy after myocardial infarction. Circ Res (2004) 2.29
Fatal gastrointestinal obstruction and hypertension in mice lacking nitric oxide-sensitive guanylyl cyclase. Proc Natl Acad Sci U S A (2007) 2.24
Ronin is essential for embryogenesis and the pluripotency of mouse embryonic stem cells. Cell (2008) 2.21
Nitric oxide synthases reveal a role for calmodulin in controlling electron transfer. Proc Natl Acad Sci U S A (1993) 2.18
Pressure-independent enhancement of cardiac hypertrophy in natriuretic peptide receptor A-deficient mice. J Clin Invest (2001) 2.03
Nitric oxide, atrial natriuretic peptide, and cyclic GMP inhibit the growth-promoting effects of norepinephrine in cardiac myocytes and fibroblasts. J Clin Invest (1998) 1.96
Transplantation of embryonic stem cells improves cardiac function in postinfarcted rats. J Appl Physiol (1985) (2002) 1.91
Inhibition of calcineurin-NFAT hypertrophy signaling by cGMP-dependent protein kinase type I in cardiac myocytes. Proc Natl Acad Sci U S A (2002) 1.88
A genetic model provides evidence that the receptor for atrial natriuretic peptide (guanylyl cyclase-A) inhibits cardiac ventricular myocyte hypertrophy. Proc Natl Acad Sci U S A (2001) 1.86
Reprogrammed mouse fibroblasts differentiate into cells of the cardiovascular and hematopoietic lineages. Stem Cells (2008) 1.83
Distinct and specific functions of cGMP-dependent protein kinases. Trends Biochem Sci (1997) 1.80
The nitric oxide pathway modulates hemangioblast activity of adult hematopoietic stem cells. Blood (2004) 1.77
Abnormal aortic valve development in mice lacking endothelial nitric oxide synthase. Circulation (2000) 1.75
Cyclic GMP signaling in cardiovascular pathophysiology and therapeutics. Pharmacol Ther (2009) 1.66
Myocardial remodeling is controlled by myocyte-targeted gene regulation of phosphodiesterase type 5. J Am Coll Cardiol (2010) 1.65
Development of heart failure and congenital septal defects in mice lacking endothelial nitric oxide synthase. Circulation (2002) 1.63
Compartmentalization of cardiac beta-adrenergic inotropy modulation by phosphodiesterase type 5. Circulation (2007) 1.61
Purification of soluble guanylyl cyclase from bovine lung by a new immunoaffinity chromatographic method. Eur J Biochem (1990) 1.60
Long-term improvement of cardiac function in rats after infarction by transplantation of embryonic stem cells. J Thorac Cardiovasc Surg (2003) 1.51
Expression of constitutively active guanylate cyclase in cardiomyocytes inhibits the hypertrophic effects of isoproterenol and aortic constriction on mouse hearts. J Biol Chem (2003) 1.50
Expression, activity, and pro-hypertrophic effects of PDE5A in cardiac myocytes. Cell Signal (2008) 1.44
Discovery of the nitric oxide signaling pathway and targets for drug development. Front Biosci (Landmark Ed) (2009) 1.40
Major occurrence of the new alpha2beta1 isoform of NO-sensitive guanylyl cyclase in brain. Cell Signal (2003) 1.35
Efficient reprogramming of human and mouse primary extra-embryonic cells to pluripotent stem cells. Genes Cells (2009) 1.35
Cloning, expression, and in situ localization of rat intestinal cGMP-dependent protein kinase II. Proc Natl Acad Sci U S A (1994) 1.31
Regulation of nitric oxide and soluble guanylyl cyclase. Brain Res Bull (2004) 1.30
Phosphorylation of the inositol 1,4,5-trisphosphate receptor by cyclic GMP-dependent protein kinase. J Biol Chem (1994) 1.29
Functional properties of a naturally occurring isoform of soluble guanylyl cyclase. Biochem J (1998) 1.27
Cloning and expression of a novel cyclic GMP-dependent protein kinase from mouse brain. J Biol Chem (1993) 1.26
Modulation of mouse cardiac function in vivo by eNOS and ANP. Am J Physiol Heart Circ Physiol (2000) 1.25
Nitric oxide facilitates cardiomyogenesis in mouse embryonic stem cells. Proc Natl Acad Sci U S A (2004) 1.25
Functional role of the soluble guanylyl cyclase alpha(1) subunit in vascular smooth muscle relaxation. Cardiovasc Res (2007) 1.23
The role of stem cells in cardiac regeneration. J Cell Mol Med (2005) 1.22
Vascular endothelial cell cyclic nucleotide phosphodiesterases and regulated cell migration: implications in angiogenesis. Mol Pharmacol (2004) 1.22
Differential expression of the cyclic GMP-stimulated phosphodiesterase PDE2A in human venous and capillary endothelial cells. J Histochem Cytochem (1999) 1.21
Soluble guanylyl cyclase: more secrets revealed. Cell Signal (2005) 1.20
Human recombinant soluble guanylyl cyclase: expression, purification, and regulation. Proc Natl Acad Sci U S A (2000) 1.16
Cardiomyocytes from human pluripotent stem cells in regenerative medicine and drug discovery. Trends Pharmacol Sci (2009) 1.16
Gene transfer of cGMP-dependent protein kinase I enhances the antihypertrophic effects of nitric oxide in cardiomyocytes. Hypertension (2002) 1.16
YC-1 activation of human soluble guanylyl cyclase has both heme-dependent and heme-independent components. Proc Natl Acad Sci U S A (2001) 1.15
Deficiency in endothelial nitric oxide synthase impairs myocardial angiogenesis. Am J Physiol Heart Circ Physiol (2002) 1.13
Cardiomyocyte differentiation of pluripotent stem cells and their use as cardiac disease models. Biochem J (2011) 1.11
Nitric oxide synthase expression and role during cardiomyogenesis. Cardiovasc Res (1999) 1.10
Growth and differentiation of rat bone marrow stromal cells: does 5-azacytidine trigger their cardiomyogenic differentiation? Cardiovasc Res (2003) 1.09
NO-cGMP signaling and regenerative medicine involving stem cells. Neurochem Res (2006) 1.08
Differential expression of genes involved in cGMP-dependent nitric oxide signaling in murine embryonic stem (ES) cells and ES cell-derived cardiomyocytes. Nitric Oxide (2005) 1.07
Up-regulation of cardiac nitric oxide synthase 1-derived nitric oxide after myocardial infarction in senescent rats. FASEB J (2003) 1.07
Stimulation of paracrine pathways with growth factors enhances embryonic stem cell engraftment and host-specific differentiation in the heart after ischemic myocardial injury. Circulation (2005) 1.07
cDNA cloning and gene expression of human type Ialpha cGMP-dependent protein kinase. Hypertension (1996) 1.06
Development of genetically engineered mice lacking all three nitric oxide synthases. J Pharmacol Sci (2006) 1.06
A variant of the alpha 2 subunit of soluble guanylyl cyclase contains an insert homologous to a region within adenylyl cyclases and functions as a dominant negative protein. J Biol Chem (1995) 1.04
Downregulation of nitrovasodilator-induced cyclic GMP accumulation in cells exposed to endotoxin or interleukin-1 beta. Br J Pharmacol (1996) 1.04
Role of nitric oxide signaling components in differentiation of embryonic stem cells into myocardial cells. Proc Natl Acad Sci U S A (2008) 1.04
cAMP phosphodiesterase inhibitors potentiate effects of prostacyclin analogs in hypoxic pulmonary vascular remodeling. Am J Physiol Lung Cell Mol Physiol (2004) 1.00
Mechanisms of tolerance to sodium nitroprusside in rat cultured aortic smooth muscle cells. Br J Pharmacol (1996) 1.00
Improvement of mouse cardiac function by hESC-derived cardiomyocytes correlates with vascularity but not graft size. Stem Cell Res (2009) 1.00
Tissue distribution of the human soluble guanylate cyclases. Biochem Biophys Res Commun (1999) 0.99
VEGF enhances functional improvement of postinfarcted hearts by transplantation of ESC-differentiated cells. J Appl Physiol (1985) (2002) 0.99
Endothelial nitric oxide synthase promotes bone marrow stromal cell migration to the ischemic myocardium via upregulation of stromal cell-derived factor-1alpha. Stem Cells (2009) 0.98
Insights into cGMP signalling derived from cGMP kinase knockout mice. Front Biosci (2005) 0.98
Embryonic and adult stem cell therapy. J Allergy Clin Immunol (2010) 0.97
Regulation of vascular smooth muscle soluble guanylate cyclase activity, mRNA, and protein levels by cAMP-elevating agents. Hypertension (1995) 0.97
Alpha1 soluble guanylyl cyclase (sGC) splice forms as potential regulators of human sGC activity. J Biol Chem (2008) 0.97
Early combined treatment with sildenafil and adipose-derived mesenchymal stem cells preserves heart function in rat dilated cardiomyopathy. J Transl Med (2010) 0.96
Post-transcriptional regulation of soluble guanylyl cyclase expression in rat aorta. J Biol Chem (2002) 0.96
Effects of cyclic nucleotide dependent protein kinases on the endoplasmic reticulum Ca2+ pump of bovine pulmonary artery. Cell Calcium (1990) 0.96
Nitric oxide determines mesodermic differentiation of mouse embryonic stem cells by activating class IIa histone deacetylases: potential therapeutic implications in a mouse model of hindlimb ischemia. Stem Cells (2010) 0.96
Genistein stimulates the osteoblastic differentiation via NO/cGMP in bone marrow culture. J Cell Biochem (2005) 0.96
Ronin is essential for embryogenesis and the pluripotency of mouse embryonic stem cells. Cell (2008) 2.21
Protein nitration in cardiovascular diseases. Pharmacol Rev (2002) 1.58
Retracted Stimulation of inducible nitric oxide by hepatitis B virus transactivator protein HBx requires MTA1 coregulator. J Biol Chem (2009) 1.56
Vascular system: role of nitric oxide in cardiovascular diseases. J Clin Hypertens (Greenwich) (2008) 1.50
Discovery of the nitric oxide signaling pathway and targets for drug development. Front Biosci (Landmark Ed) (2009) 1.40
Protein tyrosine nitration in the mitochondria from diabetic mouse heart. Implications to dysfunctional mitochondria in diabetes. J Biol Chem (2003) 1.35
Regulation of nitric oxide and soluble guanylyl cyclase. Brain Res Bull (2004) 1.30
Engrafted bone marrow-derived flk-(1+) mesenchymal stem cells regenerate skin tissue. Tissue Eng (2005) 1.29
The nature of heme/iron-induced protein tyrosine nitration. Proc Natl Acad Sci U S A (2003) 1.28
Nitric oxide (NO)--biogeneration, regulation, and relevance to human diseases. Front Biosci (2003) 1.26
Quantitative protein profiling in heart mitochondria from diabetic rats. J Biol Chem (2003) 1.21
Histone H1.2 is a substrate for denitrase, an activity that reduces nitrotyrosine immunoreactivity in proteins. Proc Natl Acad Sci U S A (2003) 1.20
Ligand selectivity of soluble guanylyl cyclase: effect of the hydrogen-bonding tyrosine in the distal heme pocket on binding of oxygen, nitric oxide, and carbon monoxide. J Biol Chem (2006) 1.17
Soluble guanylyl cyclase: the nitric oxide receptor. Methods Enzymol (2005) 1.17
NO-cGMP signaling and regenerative medicine involving stem cells. Neurochem Res (2006) 1.08
A constitutively activated mutant of human soluble guanylyl cyclase (sGC): implication for the mechanism of sGC activation. Proc Natl Acad Sci U S A (2003) 1.08
Differential expression of genes involved in cGMP-dependent nitric oxide signaling in murine embryonic stem (ES) cells and ES cell-derived cardiomyocytes. Nitric Oxide (2005) 1.07
Role of nitric oxide signaling components in differentiation of embryonic stem cells into myocardial cells. Proc Natl Acad Sci U S A (2008) 1.04
Resonance Raman and infrared spectroscopic studies of high-output forms of human soluble guanylyl cyclase. J Am Chem Soc (2005) 0.97
Alpha1 soluble guanylyl cyclase (sGC) splice forms as potential regulators of human sGC activity. J Biol Chem (2008) 0.97
Vasodilatory effects of cinnamaldehyde and its mechanism of action in the rat aorta. Vasc Health Risk Manag (2011) 0.96
Nitric oxide accelerates the recovery from burn wounds. World J Surg (2007) 0.96
Nitric oxide: a guardian for vascular grafts? Chem Rev (2011) 0.95
A short history of cGMP, guanylyl cyclases, and cGMP-dependent protein kinases. Handb Exp Pharmacol (2009) 0.95
Differential expression of nitric oxide signaling components in undifferentiated and differentiated human embryonic stem cells. Stem Cells Dev (2006) 0.95
Generation and role of angiostatin in human platelets. Blood (2003) 0.95
Cyclic GMP-independent mechanisms contribute to the inhibition of platelet adhesion by nitric oxide donor: a role for alpha-actinin nitration. Proc Natl Acad Sci U S A (2006) 0.92
Pyridopyrimidine derivatives as inhibitors of cyclic nucleotide synthesis: Application for treatment of diarrhea. Proc Natl Acad Sci U S A (2008) 0.92
Effects of nitric oxide on skin burn wound healing. J Burn Care Res (2008) 0.92
CCTeta, a novel soluble guanylyl cyclase-interacting protein. J Biol Chem (2004) 0.92
Upregulation of S100 calcium-binding protein A9 is required for induction of smooth muscle cell proliferation by a periodontal pathogen. FEBS Lett (2008) 0.92
Proteomic modification by nitric oxide. J Pharmacol Sci (2006) 0.92
Role of soluble guanylyl cyclase-cyclic GMP signaling in tumor cell proliferation. Nitric Oxide (2009) 0.90
NO-cGMP signaling in development and stem cells. Mol Genet Metab (2005) 0.89
The placental cholinergic system: localization to the cytotrophoblast and modulation of nitric oxide. Cell Commun Signal (2006) 0.87
RNA splicing in regulation of nitric oxide receptor soluble guanylyl cyclase. Nitric Oxide (2011) 0.86
CCAAT-binding factor regulates expression of the beta1 subunit of soluble guanylyl cyclase gene in the BE2 human neuroblastoma cell line. Proc Natl Acad Sci U S A (2003) 0.86
Immunolocalization of nitric oxide synthase isoforms in human archival and rat tissues, and cultured cells. J Neurosci Methods (2011) 0.86
Helminth regulation of host IL-4Ralpha/Stat6 signaling: mechanism underlying NOS-2 inhibition by Trichinella spiralis. Proc Natl Acad Sci U S A (2005) 0.85
Vascular dilation by paeonol--a mechanism study. Vascul Pharmacol (2010) 0.84
NOS-2 signaling and cancer therapy. IUBMB Life (2012) 0.84
Dynamic interplay between nitration and phosphorylation of tubulin cofactor B in the control of microtubule dynamics. Proc Natl Acad Sci U S A (2007) 0.83
Nitric oxide receptor soluble guanylyl cyclase undergoes splicing regulation in differentiating human embryonic cells. Stem Cells Dev (2010) 0.82
Nitric oxide signaling in vascular biology. J Am Soc Hypertens (2010) 0.82
LPS/IFNgamma-induced RAW 264.7 apoptosis is regulated by both nitric oxide-dependent and -independent pathways involving JNK and the Bcl-2 family. Cell Cycle (2007) 0.82
Curcumin induces differentiation of embryonic stem cells through possible modulation of nitric oxide-cyclic GMP pathway. Protein Cell (2012) 0.82
Targeting different types of human meningioma and glioma cells using a novel adenoviral vector expressing GFP-TRAIL fusion protein from hTERT promoter. Cancer Cell Int (2011) 0.81
Restoring soluble guanylyl cyclase expression and function blocks the aggressive course of glioma. Mol Pharmacol (2011) 0.81
The role of superoxide anion in the inhibitory effect of SIN-1 in thrombin-activated human platelet adhesion. Eur J Pharmacol (2009) 0.81
Mapping sites of tyrosine nitration by matrix-assisted laser desorption/ionization mass spectrometry. Methods Enzymol (2005) 0.80
Hydrogen peroxide alters splicing of soluble guanylyl cyclase and selectively modulates expression of splicing regulators in human cancer cells. PLoS One (2012) 0.80
Mass spectrometry-based relative quantification of human neutrophil peptides 1, 2, and 3 from biological samples. Mol Immunol (2005) 0.80
The relaxant activity of 4,7-dimethyl-1,2,5-oxadiazolo[3,4-d]-pyridazine 1,5,6-trioxide in the mouse corpus cavernosum. J Pharmacol Exp Ther (2005) 0.79
Effects of the JNK inhibitor anthra[1,9-cd]pyrazol-6(2H)-one (SP-600125) on soluble guanylyl cyclase alpha1 gene regulation and cGMP synthesis. Am J Physiol Cell Physiol (2005) 0.79
Mechanism of vasculitis and aneurysms in Kawasaki disease: role of nitric oxide. Nitric Oxide (2003) 0.78
Nitric oxide signaling and neural stem cell differentiation in peripheral nerve regeneration. Eplasty (2010) 0.77
Novel pyridopyrimidine derivatives as inhibitors of stable toxin a (STa) induced cGMP synthesis. Bioorg Med Chem Lett (2009) 0.77
The excitement and rewards of research with our discovery of some of the biological effects of nitric oxide. Circ Res (2003) 0.77
Stimulation of inducible nitric oxide by hepatitis B virus transactivator protein HBx requires MTA1 coregulator. J Biol Chem (2016) 0.75
sGC-cGMP signaling: target for anticancer therapy. Adv Exp Med Biol (2014) 0.75
Ferid Murad, MD, PhD: a conversation with the editor. Am J Cardiol (2004) 0.75
Heart of science. Nature (2011) 0.75
Stimulation of inducible nitric oxide by hepatitis B virus transactivator protein-HBx requires MTA1 coregulator. J Biol Chem (2017) 0.75