Published in J Signal Transduct on October 15, 2011
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Modular nanotransporters: a versatile approach for enhancing nuclear delivery and cytotoxicity of Auger electron-emitting 125I. EJNMMI Res (2012) 0.93
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Nuclear importin α and its physiological importance. Commun Integr Biol (2012) 0.79
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Gating neural development and aging via nuclear pores. Cell Res (2012) 0.75
Quantitative proteomic profiling of paired cancerous and normal colon epithelial cells isolated freshly from colorectal cancer patients. Proteomics Clin Appl (2016) 0.75
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Mammalian stress granules and processing bodies. Methods Enzymol (2007) 4.76
Radical-free biology of oxidative stress. Am J Physiol Cell Physiol (2008) 4.33
NF-κB, inflammation, and metabolic disease. Cell Metab (2011) 4.00
Age-dependent deterioration of nuclear pore complexes causes a loss of nuclear integrity in postmitotic cells. Cell (2009) 3.95
Crosstalk of reactive oxygen species and NF-κB signaling. Cell Res (2010) 3.71
The importance of glutathione in human disease. Biomed Pharmacother (2003) 3.61
Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment. Drugs Aging (2001) 3.36
Dynamic O-GlcNAc modification of nucleocytoplasmic proteins in response to stress. A survival response of mammalian cells. J Biol Chem (2004) 3.35
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Oxidative stress, insulin signaling, and diabetes. Free Radic Biol Med (2010) 3.26
Nuclear targeting signal recognition: a key control point in nuclear transport? Bioessays (2000) 3.17
NADPH oxidases, reactive oxygen species, and hypertension: clinical implications and therapeutic possibilities. Diabetes Care (2008) 3.07
Metals, oxidative stress and neurodegenerative disorders. Mol Cell Biochem (2010) 3.02
Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs. Cell (2009) 2.98
More than folding: localized functions of cytosolic chaperones. Trends Biochem Sci (2003) 2.95
An integrated view of oxidative stress in aging: basic mechanisms, functional effects, and pathological considerations. Am J Physiol Regul Integr Comp Physiol (2006) 2.84
AMPK: a key regulator of energy balance in the single cell and the whole organism. Int J Obes (Lond) (2008) 2.77
The nuclear pore complex and nuclear transport. Cold Spring Harb Perspect Biol (2010) 2.71
Diabetic nephropathy: mechanisms of renal disease progression. Exp Biol Med (Maywood) (2008) 2.70
Superoxide dismutases: role in redox signaling, vascular function, and diseases. Antioxid Redox Signal (2011) 2.66
O-linked beta-N-acetylglucosamine (O-GlcNAc): Extensive crosstalk with phosphorylation to regulate signaling and transcription in response to nutrients and stress. Biochim Biophys Acta (2009) 2.64
Protein carbonylation, cellular dysfunction, and disease progression. J Cell Mol Med (2006) 2.59
NADPH oxidase-mediated redox signaling: roles in cellular stress response, stress tolerance, and tissue repair. Pharmacol Rev (2011) 2.53
Regulation of nuclear transport: central role in development and transformation? Traffic (2005) 2.51
Oxidative stress and metabolic syndrome. Life Sci (2009) 2.41
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CRM1-mediated nuclear export: to the pore and beyond. Trends Cell Biol (2007) 2.32
RNA granules: the good, the bad and the ugly. Cell Signal (2010) 2.31
The aging stress response. Mol Cell (2010) 2.19
High-mobility group box 1, oxidative stress, and disease. Antioxid Redox Signal (2011) 2.19
Peroxisomes and oxidative stress. Biochim Biophys Acta (2006) 2.17
Hydrogen peroxide stimulates macrophages and monocytes to actively release HMGB1. J Leukoc Biol (2006) 2.17
The diverse functions of GAPDH: views from different subcellular compartments. Cell Signal (2010) 2.15
Nucleocytoplasmic shuttling of HMGB1 is regulated by phosphorylation that redirects it toward secretion. J Immunol (2006) 2.14
Oxidative stress and aberrant signaling in aging and cognitive decline. Aging Cell (2007) 2.13
Oxidative stress and neurotoxicity. Chem Res Toxicol (2007) 2.12
Nuclear-cytoplasmic transport of EGFR involves receptor endocytosis, importin beta1 and CRM1. J Cell Biochem (2006) 2.11
Hydrogen peroxide in the human body. FEBS Lett (2000) 2.10
Nuclear EGFR signalling network in cancers: linking EGFR pathway to cell cycle progression, nitric oxide pathway and patient survival. Br J Cancer (2006) 2.09
S-glutathiolation of Ras mediates redox-sensitive signaling by angiotensin II in vascular smooth muscle cells. J Biol Chem (2004) 2.09
New insights into the role of mitochondria in aging: mitochondrial dynamics and more. J Cell Sci (2010) 2.03
Oxidative stress: the vulnerable beta-cell. Biochem Soc Trans (2008) 1.98
Retracted Nuclear import and export signals in control of Nrf2. J Biol Chem (2005) 1.98
Thiol-based redox switches in eukaryotic proteins. Antioxid Redox Signal (2009) 1.97
AMPK inhibition in health and disease. Crit Rev Biochem Mol Biol (2010) 1.93
Mitochondrial biogenesis in the metabolic syndrome and cardiovascular disease. J Mol Med (Berl) (2010) 1.90
Translationally repressed mRNA transiently cycles through stress granules during stress. Mol Biol Cell (2008) 1.84
Cellular stress responses, the hormesis paradigm, and vitagenes: novel targets for therapeutic intervention in neurodegenerative disorders. Antioxid Redox Signal (2010) 1.77
p53 and NF-κB: different strategies for responding to stress lead to a functional antagonism. FASEB J (2010) 1.77
Sequestration of TRAF2 into stress granules interrupts tumor necrosis factor signaling under stress conditions. Mol Cell Biol (2005) 1.75
Oxygen as a friend and enemy: How to combat the mutational potential of 8-oxo-guanine. DNA Repair (Amst) (2010) 1.70
Superoxide dismutases and their impact upon human health. Mol Aspects Med (2005) 1.67
Free radicals and antioxidants - quo vadis? Trends Pharmacol Sci (2011) 1.65
Phosphoproteomics reveals new ERK MAP kinase targets and links ERK to nucleoporin-mediated nuclear transport. Nat Struct Mol Biol (2009) 1.64
ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function. Toxicol Appl Pharmacol (2009) 1.63
Molecular targets of oxidative stress. Biochem J (2011) 1.60
Forkhead homeobox type O transcription factors in the responses to oxidative stress. Antioxid Redox Signal (2010) 1.59
Nucleocytoplasmic shuttling of Smad proteins. Cell Res (2009) 1.55
Proteins as biomarkers of oxidative/nitrosative stress in diseases: the contribution of redox proteomics. Mass Spectrom Rev (2004) 1.54
NADPH oxidases in cardiovascular disease. Free Radic Biol Med (2010) 1.53
Oxidative stress in early diabetic nephropathy: fueling the fire. Nat Rev Endocrinol (2010) 1.51
GAPDH as a sensor of NO stress. Biochim Biophys Acta (2006) 1.50
Cardiac aging in mice and humans: the role of mitochondrial oxidative stress. Trends Cardiovasc Med (2009) 1.48
Mitochondrial ROS generation and its regulation: mechanisms involved in H(2)O(2) signaling. Antioxid Redox Signal (2010) 1.47
Review of molecular mechanisms involved in the activation of the Nrf2-ARE signaling pathway by chemopreventive agents. Methods Mol Biol (2010) 1.46
AMP-activated protein kinase-regulated phosphorylation and acetylation of importin alpha1: involvement in the nuclear import of RNA-binding protein HuR. J Biol Chem (2004) 1.46
Cellular stresses induce the nuclear accumulation of importin alpha and cause a conventional nuclear import block. J Cell Biol (2004) 1.46
Direct activation of RhoA by reactive oxygen species requires a redox-sensitive motif. PLoS One (2009) 1.46
Nuclear export of Smad2 and Smad3 by RanBP3 facilitates termination of TGF-beta signaling. Dev Cell (2009) 1.45
The redox regulation of PI 3-kinase-dependent signaling. Antioxid Redox Signal (2006) 1.39
PTEN nuclear localization is regulated by oxidative stress and mediates p53-dependent tumor suppression. Mol Cell Biol (2008) 1.38
Localization of AMP kinase is regulated by stress, cell density, and signaling through the MEK-->ERK1/2 pathway. Am J Physiol Cell Physiol (2007) 1.38
The translocon Sec61beta localized in the inner nuclear membrane transports membrane-embedded EGF receptor to the nucleus. J Biol Chem (2010) 1.36
Oxidatively modified glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and Alzheimer's disease: many pathways to neurodegeneration. J Alzheimers Dis (2010) 1.34
Redox characteristics of the eukaryotic cytosol. Biochim Biophys Acta (2007) 1.34
Oxidative stress and endothelial dysfunction in cerebrovascular disease. Front Biosci (Landmark Ed) (2011) 1.34
Signal propagation from membrane messengers to nuclear effectors revealed by reporters of phosphoinositide dynamics and Akt activity. Proc Natl Acad Sci U S A (2005) 1.34
Ran-binding protein 3 phosphorylation links the Ras and PI3-kinase pathways to nucleocytoplasmic transport. Mol Cell (2008) 1.33
Transforming growth factor-beta activation in the lung: focus on fibrosis and reactive oxygen species. Antioxid Redox Signal (2008) 1.33
Localization of AMP kinase is regulated by stress, cell density, and signaling through the MEK-->ERK1/2 pathway. Am J Physiol Cell Physiol (2007) 1.38
Oxidative stress mislocalizes and retains transport factor importin-alpha and nucleoporins Nup153 and Nup88 in nuclei where they generate high molecular mass complexes. Biochim Biophys Acta (2007) 1.04
Stress inhibits nucleocytoplasmic shuttling of heat shock protein hsc70. Am J Physiol Cell Physiol (2005) 1.04
Analysis of signaling events by combining high-throughput screening technology with computer-based image analysis. Sci Signal (2008) 1.01
Oxidative stress inhibits nuclear protein export by multiple mechanisms that target FG nucleoporins and Crm1. Mol Biol Cell (2009) 1.00
AMP kinase: the missing link between type 2 diabetes and neurodegenerative diseases? Trends Mol Med (2011) 1.00
Gold nanoparticles induce nuclear damage in breast cancer cells, which is further amplified by hyperthermia. Cell Mol Life Sci (2014) 0.96
Dissecting the signaling events that impact classical nuclear import and target nuclear transport factors. PLoS One (2009) 0.92
Chaperones and multitasking proteins in the nucleolus: networking together for survival? Trends Biochem Sci (2010) 0.91
Interplay between MEK and PI3 kinase signaling regulates the subcellular localization of protein kinases ERK1/2 and Akt upon oxidative stress. FEBS Lett (2009) 0.90
The localization of nuclear exporters of the importin-beta family is regulated by Snf1 kinase, nutrient supply and stress. Biochim Biophys Acta (2007) 0.89
Identification of Novel Stress Granule Components That Are Involved in Nuclear Transport. PLoS One (2013) 0.88
Nucleolar targeting of the chaperone hsc70 is regulated by stress, cell signaling, and a composite targeting signal which is controlled by autoinhibition. J Biol Chem (2010) 0.88
The carrier Msn5p/Kap142p promotes nuclear export of the hsp70 Ssa4p and relocates in response to stress. Mol Microbiol (2006) 0.88
Nuclear accumulation of the small GTPase Gsp1p depends on nucleoporins Nup133p, Rat2p/Nup120p, Nup85p, Nic96p, and the acetyl-CoA carboxylase Acc1p. J Biol Chem (2003) 0.87
Pharmacological AMP-kinase activators have compartment-specific effects on cell physiology. Am J Physiol Cell Physiol (2011) 0.85
Monitoring the disruption of nuclear envelopes in interphase cells with GFP-beta-galactosidase. J Biomol Tech (2005) 0.83
Regulated nuclear accumulation of the yeast hsp70 Ssa4p in ethanol-stressed cells is mediated by the N-terminal domain, requires the nuclear carrier Nmd5p and protein kinase C. FASEB J (2004) 0.82
Traffic control at the nuclear pore. Nucleus (2010) 0.82
Computer-based fluorescence quantification: a novel approach to study nucleolar biology. BMC Cell Biol (2011) 0.82
Identification of novel markers that demarcate the nucleolus during severe stress and chemotherapeutic treatment. PLoS One (2013) 0.80
Ceramide synthase inhibitor fumonisin B1 inhibits apoptotic cell death in SCC17B human head and neck squamous carcinoma cells after Pc4 photosensitization. Photochem Photobiol Sci (2014) 0.79
Automated detection and quantification of granular cell compartments. Microsc Microanal (2013) 0.78
Nucleoli and stress granules: connecting distant relatives. Traffic (2014) 0.75
Rapid purification of the outer mitochondrial membrane protein Por1p from Saccharomyces cerevisiae. Biotechniques (2004) 0.75