Published in Nat Immunol on November 18, 2002
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nat Genet (2010) 8.48
Immune selection for altered antigen processing leads to cytotoxic T lymphocyte escape in chronic HIV-1 infection. J Exp Med (2004) 4.52
Towards a systems understanding of MHC class I and MHC class II antigen presentation. Nat Rev Immunol (2011) 4.31
The ER aminopeptidase, ERAP1, trims precursors to lengths of MHC class I peptides by a "molecular ruler" mechanism. Proc Natl Acad Sci U S A (2005) 2.47
The role of the proteasome in generating cytotoxic T-cell epitopes: insights obtained from improved predictions of proteasomal cleavage. Immunogenetics (2005) 2.40
Balancing selection maintains a form of ERAP2 that undergoes nonsense-mediated decay and affects antigen presentation. PLoS Genet (2010) 2.14
Investigating the genetic association between ERAP1 and ankylosing spondylitis. Hum Mol Genet (2009) 1.95
The quality control of MHC class I peptide loading. Curr Opin Cell Biol (2008) 1.91
Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims MHC class I-presented peptides in vivo and plays an important role in immunodominance. Proc Natl Acad Sci U S A (2006) 1.91
Functionally distinct ERAP1 allotype combinations distinguish individuals with Ankylosing Spondylitis. Proc Natl Acad Sci U S A (2014) 1.90
In vivo role of ER-associated peptidase activity in tailoring peptides for presentation by MHC class Ia and class Ib molecules. J Exp Med (2006) 1.79
Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming. Proc Natl Acad Sci U S A (2011) 1.64
From HLA-B27 to spondyloarthritis: a journey through the ER. Immunol Rev (2010) 1.52
Association of antigen processing machinery and HLA class I defects with clinicopathological outcome in cervical carcinoma. Cancer Immunol Immunother (2007) 1.47
ERAAP synergizes with MHC class I molecules to make the final cut in the antigenic peptide precursors in the endoplasmic reticulum. Immunity (2006) 1.43
Structural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1. Nat Struct Mol Biol (2011) 1.42
Endoplasmic reticulum aminopeptidases: Biology and pathogenic potential. Nat Rev Rheumatol (2010) 1.39
Naturally occurring ERAP1 haplotypes encode functionally distinct alleles with fine substrate specificity. J Immunol (2013) 1.34
The specificity of trimming of MHC class I-presented peptides in the endoplasmic reticulum. J Immunol (2009) 1.30
A common single nucleotide polymorphism in endoplasmic reticulum aminopeptidase 2 induces a specificity switch that leads to altered antigen processing. J Immunol (2012) 1.27
EpiJen: a server for multistep T cell epitope prediction. BMC Bioinformatics (2006) 1.26
CD13 regulates dendritic cell cross-presentation and T cell responses by inhibiting receptor-mediated antigen uptake. J Immunol (2012) 1.24
Classification of juvenile spondyloarthritis: Enthesitis-related arthritis and beyond. Nat Rev Rheumatol (2010) 1.23
The internal sequence of the peptide-substrate determines its N-terminus trimming by ERAP1. PLoS One (2008) 1.23
Coping with loss of perfection in the MHC class I peptide repertoire. Curr Opin Immunol (2008) 1.21
A multiepitope subunit vaccine conveys protection against extraintestinal pathogenic Escherichia coli in mice. Infect Immun (2010) 1.19
Escape mutations alter proteasome processing of major histocompatibility complex class I-restricted epitopes in persistent hepatitis C virus infection. J Virol (2005) 1.15
Proteases in MHC class I presentation and cross-presentation. J Immunol (2010) 1.15
Functional interaction of the ankylosing spondylitis-associated endoplasmic reticulum aminopeptidase 1 polymorphism and HLA-B27 in vivo. Mol Cell Proteomics (2012) 1.15
Rationally designed inhibitor targeting antigen-trimming aminopeptidases enhances antigen presentation and cytotoxic T-cell responses. Proc Natl Acad Sci U S A (2013) 1.11
Probing the S1 specificity pocket of the aminopeptidases that generate antigenic peptides. Biochem J (2011) 1.10
Psoriasis and other complex trait dermatoses: from Loci to functional pathways. J Invest Dermatol (2011) 1.07
Placental leucine aminopeptidase efficiently generates mature antigenic peptides in vitro but in patterns distinct from endoplasmic reticulum aminopeptidase 1. J Immunol (2010) 1.05
Puromycin-sensitive aminopeptidase is the major peptidase responsible for digesting polyglutamine sequences released by proteasomes during protein degradation. EMBO J (2007) 1.04
Cross-presentation: dendritic cells and macrophages bite off more than they can chew! Immunology (2004) 1.01
T-cell tolerance for variability in an HLA class I-presented influenza A virus epitope. J Virol (2009) 1.00
Aminopeptidase substrate preference affects HIV epitope presentation and predicts immune escape patterns in HIV-infected individuals. J Immunol (2012) 0.98
Ovalbumin-derived precursor peptides are transferred sequentially from gp96 and calreticulin to MHC class I in the endoplasmic reticulum. J Immunol (2010) 0.98
Combined effects of ankylosing spondylitis-associated ERAP1 polymorphisms outside the catalytic and peptide-binding sites on the processing of natural HLA-B27 ligands. J Biol Chem (2013) 0.98
ERAP1 genetic variations associated with HLA-B27 interaction and disease severity of syndesmophytes formation in Taiwanese ankylosing spondylitis. Arthritis Res Ther (2012) 0.97
Analysis of the role of tripeptidyl peptidase II in MHC class I antigen presentation in vivo. J Immunol (2009) 0.97
Re-examining class-I presentation and the DRiP hypothesis. Trends Immunol (2014) 0.97
ERAP1 biology and assessment in Ankylosing Spondylitis. Proc Natl Acad Sci U S A (2015) 0.97
Antigenic peptide trimming by ER aminopeptidases--insights from structural studies. Mol Immunol (2013) 0.97
Hepatitis C virus and ethanol alter antigen presentation in liver cells. World J Gastroenterol (2009) 0.94
Differential contribution of TAP and tapasin to HLA class I antigen expression. Immunology (2008) 0.93
The final cut: how ERAP1 trims MHC ligands to size. Nat Immunol (2002) 0.91
The association between seven ERAP1 polymorphisms and ankylosing spondylitis susceptibility: a meta-analysis involving 8,530 cases and 12,449 controls. Rheumatol Int (2011) 0.90
Identification of potential HLA class I and class II epitope precursors associated with heat shock protein 70 (HSPA). Cell Stress Chaperones (2010) 0.90
ERAAP and tapasin independently edit the amino and carboxyl termini of MHC class I peptides. J Immunol (2013) 0.90
The cytoplasmic peptidase DPP9 is rate-limiting for degradation of proline-containing peptides. J Biol Chem (2009) 0.90
Endoplasmic reticulum aminopeptidase-1 alleles associated with increased risk of ankylosing spondylitis reduce HLA-B27 mediated presentation of multiple antigens. Autoimmunity (2013) 0.90
The messenger and the message: gp96 (GRP94)-peptide interactions in cellular immunity. Cell Stress Chaperones (2004) 0.89
Nonclassical antigen-processing pathways are required for MHC class II-restricted direct tumor recognition by NY-ESO-1-specific CD4(+) T cells. Cancer Immunol Res (2013) 0.89
The role of insulin-regulated aminopeptidase in MHC class I antigen presentation. Front Immunol (2012) 0.88
Impaired methylation as a novel mechanism for proteasome suppression in liver cells. Biochem Biophys Res Commun (2009) 0.87
Comparison against 186 canid whole-genome sequences reveals survival strategies of an ancient clonally transmissible canine tumor. Genome Res (2015) 0.87
Structural insights into the molecular ruler mechanism of the endoplasmic reticulum aminopeptidase ERAP1. Sci Rep (2011) 0.86
What is the role of alternate splicing in antigen presentation by major histocompatibility complex class I molecules? Immunol Res (2010) 0.86
Ankylosing spondylitis: from cells to genes. Int J Inflam (2013) 0.86
Substrate-induced protein stabilization reveals a predominant contribution from mature proteins to peptides presented on MHC class I. J Immunol (2013) 0.85
Identification of naturally processed ligands in the C57BL/6 mouse using large-scale mass spectrometric peptide sequencing and bioinformatics prediction. Immunogenetics (2009) 0.85
The intracellular antigen transport machinery TAP in adaptive immunity and virus escape mechanisms. J Bioenerg Biomembr (2005) 0.84
A role for naturally occurring alleles of endoplasmic reticulum aminopeptidases in tumor immunity and cancer pre-disposition. Front Oncol (2014) 0.84
Ethanol metabolism alters major histocompatibility complex class I-restricted antigen presentation in liver cells. Hepatology (2009) 0.84
p53 increases MHC class I expression by upregulating the endoplasmic reticulum aminopeptidase ERAP1. Nat Commun (2013) 0.84
Late multiple organ surge in interferon-regulated target genes characterizes staphylococcal enterotoxin B lethality. PLoS One (2014) 0.83
Multiple viral ligands naturally presented by different class I molecules in transporter antigen processing-deficient vaccinia virus-infected cells. J Virol (2011) 0.83
Role of endoplasmic reticulum aminopeptidases in health and disease: from infection to cancer. Int J Mol Sci (2012) 0.83
Identification of an alternate splice form of tapasin in human melanoma. Hum Immunol (2010) 0.83
Structural Basis for Antigenic Peptide Recognition and Processing by Endoplasmic Reticulum (ER) Aminopeptidase 2. J Biol Chem (2015) 0.83
Sequence-specific alterations of epitope production by HIV protease inhibitors. J Immunol (2014) 0.83
Antigen Presentation, Autoantigens, and Immune Regulation in Multiple Sclerosis and Other Autoimmune Diseases. Front Immunol (2015) 0.83
Different antigen-processing activities in dendritic cells, macrophages, and monocytes lead to uneven production of HIV epitopes and affect CTL recognition. J Immunol (2014) 0.82
Endoplasmic reticulum aminopeptidase-1 functions regulate key aspects of the innate immune response. PLoS One (2013) 0.82
Intracellular Transport Routes for MHC I and Their Relevance for Antigen Cross-Presentation. Front Immunol (2015) 0.82
Differences in genetic variation in antigen-processing machinery components and association with cervical carcinoma risk in two Indonesian populations. Immunogenetics (2015) 0.81
Present Yourself! By MHC Class I and MHC Class II Molecules. Trends Immunol (2016) 0.81
Alternative Antigen Processing for MHC Class I: Multiple Roads Lead to Rome. Front Immunol (2015) 0.80
Concerted in vitro trimming of viral HLA-B27-restricted ligands by human ERAP1 and ERAP2 aminopeptidases. PLoS One (2013) 0.80
Endoplasmic reticulum aminopeptidase 1 and rheumatic disease: functional variation. Curr Opin Rheumatol (2015) 0.80
Heat shock protein and gliadin peptide promote development of peptidase antibodies in children with autism and patients with autoimmune disease. Clin Diagn Lab Immunol (2004) 0.80
Identification of QTL genes for BMD variation using both linkage and gene-based association approaches. Hum Genet (2011) 0.80
Mechanisms of HIV protein degradation into epitopes: implications for vaccine design. Viruses (2014) 0.79
Comparative expression profiling for human endoplasmic reticulum-resident aminopeptidases 1 and 2 in normal kidney versus distinct renal cell carcinoma subtypes. Int J Clin Exp Pathol (2013) 0.79
ERAP1 functions override the intrinsic selection of specific antigens as immunodominant peptides, thereby altering the potency of antigen-specific cytolytic and effector memory T-cell responses. Int Immunol (2014) 0.78
ERAP1-ERAP2 dimers trim MHC I-bound precursor peptides; implications for understanding peptide editing. Sci Rep (2016) 0.78
ERAAP modulation: A possible novel strategy for cancer immunotherapy? Oncoimmunology (2012) 0.78
Crystallization and preliminary X-ray diffraction analysis of human endoplasmic reticulum aminopeptidase 2. Acta Crystallogr Sect F Struct Biol Cryst Commun (2012) 0.78
An MHC class I immune evasion gene of Marek׳s disease virus. Virology (2014) 0.78
Characterizing the specificity and cooperation of aminopeptidases in the cytosol and endoplasmic reticulum during MHC class I antigen presentation. J Immunol (2010) 0.78
Allele-dependent processing pathways generate the endogenous human leukocyte antigen (HLA) class I peptide repertoire in transporters associated with antigen processing (TAP)-deficient cells. J Biol Chem (2011) 0.78
Mass Spectrometry Profiling of HLA-Associated Peptidomes in Mono-allelic Cells Enables More Accurate Epitope Prediction. Immunity (2017) 0.77
The Enigma of Tripeptidyl-Peptidase II: Dual Roles in Housekeeping and Stress. J Oncol (2010) 0.77
Manipulation of EAT-2 expression promotes induction of multiple beneficial regulatory and effector functions of the human innate immune system as a novel immunomodulatory strategy. Int Immunol (2013) 0.77
Molecular backgrounds of ERAP1 downregulation in cervical carcinoma. Anal Cell Pathol (Amst) (2015) 0.77
Genetic associations and functional characterization of M1 aminopeptidases and immune-mediated diseases. Genes Immun (2014) 0.77
Just one position-independent lysine residue can direct MelanA into proteasomal degradation following N-terminal fusion of ubiquitin. PLoS One (2013) 0.76
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy (2007) 20.92
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol (2008) 16.65
Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy. Cell (2004) 11.33
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature (2010) 10.60
FoxO3 controls autophagy in skeletal muscle in vivo. Cell Metab (2007) 8.90
Molecular identification of a danger signal that alerts the immune system to dying cells. Nature (2003) 8.90
How dying cells alert the immune system to danger. Nat Rev Immunol (2008) 8.63
FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells. Cell Metab (2007) 8.05
Identification of a key pathway required for the sterile inflammatory response triggered by dying cells. Nat Med (2007) 7.25
Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression. FASEB J (2004) 7.02
PGC-1alpha protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription. Proc Natl Acad Sci U S A (2006) 5.28
Reversal of cancer cachexia and muscle wasting by ActRIIB antagonism leads to prolonged survival. Cell (2010) 5.23
Docking of the proteasomal ATPases' carboxyl termini in the 20S proteasome's alpha ring opens the gate for substrate entry. Mol Cell (2007) 4.54
Immune selection for altered antigen processing leads to cytotoxic T lymphocyte escape in chronic HIV-1 infection. J Exp Med (2004) 4.52
Protein degradation by the ubiquitin-proteasome pathway in normal and disease states. J Am Soc Nephrol (2006) 4.01
Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages. J Biol Chem (2007) 3.68
Mechanism of gate opening in the 20S proteasome by the proteasomal ATPases. Mol Cell (2008) 3.49
Rapid disuse and denervation atrophy involve transcriptional changes similar to those of muscle wasting during systemic diseases. FASEB J (2006) 3.27
An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides. Nat Immunol (2002) 3.22
MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals. J Clin Invest (2006) 3.21
ATP hydrolysis by the proteasome regulatory complex PAN serves multiple functions in protein degradation. Mol Cell (2003) 3.14
During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation. J Cell Biol (2009) 3.03
Eukaryotic proteasomes cannot digest polyglutamine sequences and release them during degradation of polyglutamine-containing proteins. Mol Cell (2004) 2.89
IGF-I stimulates muscle growth by suppressing protein breakdown and expression of atrophy-related ubiquitin ligases, atrogin-1 and MuRF1. Am J Physiol Endocrinol Metab (2004) 2.82
ATP binding to PAN or the 26S ATPases causes association with the 20S proteasome, gate opening, and translocation of unfolded proteins. Mol Cell (2005) 2.82
Importance of the different proteolytic sites of the proteasome and the efficacy of inhibitors varies with the protein substrate. J Biol Chem (2006) 2.59
Monitoring activity and inhibition of 26S proteasomes with fluorogenic peptide substrates. Methods Enzymol (2005) 2.49
The ER aminopeptidase, ERAP1, trims precursors to lengths of MHC class I peptides by a "molecular ruler" mechanism. Proc Natl Acad Sci U S A (2005) 2.47
The FOXO3a transcription factor regulates cardiac myocyte size downstream of AKT signaling. J Biol Chem (2005) 2.44
hRpn13/ADRM1/GP110 is a novel proteasome subunit that binds the deubiquitinating enzyme, UCH37. EMBO J (2006) 2.35
Patterns of gene expression in atrophying skeletal muscles: response to food deprivation. FASEB J (2002) 2.29
ATP binds to proteasomal ATPases in pairs with distinct functional effects, implying an ordered reaction cycle. Cell (2011) 2.27
Protein degradation and the generation of MHC class I-presented peptides. Adv Immunol (2002) 2.17
Important role of cathepsin S in generating peptides for TAP-independent MHC class I crosspresentation in vivo. Immunity (2004) 2.13
The importance of the proteasome and subsequent proteolytic steps in the generation of antigenic peptides. Mol Immunol (2002) 2.13
Ubiquitinated proteins activate the proteasome by binding to Usp14/Ubp6, which causes 20S gate opening. Mol Cell (2009) 2.10
Uric acid promotes an acute inflammatory response to sterile cell death in mice. J Clin Invest (2010) 1.97
Cancer vulnerabilities unveiled by genomic loss. Cell (2012) 1.95
Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims MHC class I-presented peptides in vivo and plays an important role in immunodominance. Proc Natl Acad Sci U S A (2006) 1.91
IMP3 predicts aggressive superficial urothelial carcinoma of the bladder. Clin Cancer Res (2008) 1.87
Trehalose synthesis is induced upon exposure of Escherichia coli to cold and is essential for viability at low temperatures. Proc Natl Acad Sci U S A (2002) 1.85
Ubiquitin ligase Nedd4 promotes alpha-synuclein degradation by the endosomal-lysosomal pathway. Proc Natl Acad Sci U S A (2011) 1.85
Post-proteasomal antigen processing for major histocompatibility complex class I presentation. Nat Immunol (2004) 1.83
TNF-alpha increases ubiquitin-conjugating activity in skeletal muscle by up-regulating UbcH2/E220k. FASEB J (2003) 1.83
Isolation of mammalian 26S proteasomes and p97/VCP complexes using the ubiquitin-like domain from HHR23B reveals novel proteasome-associated proteins. Biochemistry (2009) 1.78
Immuno- and constitutive proteasomes do not differ in their abilities to degrade ubiquitinated proteins. Cell (2013) 1.74
Priming of T cells by exogenous antigen cross-presented on MHC class I molecules. Curr Opin Immunol (2005) 1.72
Heat shock and oxygen radicals stimulate ubiquitin-dependent degradation mainly of newly synthesized proteins. J Cell Biol (2008) 1.71
ATP-dependent steps in the binding of ubiquitin conjugates to the 26S proteasome that commit to degradation. Mol Cell (2010) 1.68
Properties of the hybrid form of the 26S proteasome containing both 19S and PA28 complexes. EMBO J (2002) 1.68
BMP signaling controls muscle mass. Nat Genet (2013) 1.68
Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member, ErbB3. Proc Natl Acad Sci U S A (2002) 1.68
Peroxisome proliferator-activated receptor gamma coactivator 1alpha or 1beta overexpression inhibits muscle protein degradation, induction of ubiquitin ligases, and disuse atrophy. J Biol Chem (2010) 1.66
Analysis of RNA-binding protein IMP3 to predict metastasis and prognosis of renal-cell carcinoma: a retrospective study. Lancet Oncol (2006) 1.61
Interactions of PAN's C-termini with archaeal 20S proteasome and implications for the eukaryotic proteasome-ATPase interactions. EMBO J (2009) 1.60
Mycobacterium tuberculosis ClpP1 and ClpP2 function together in protein degradation and are required for viability in vitro and during infection. PLoS Pathog (2012) 1.60
Indoleamine 2,3-dioxygenase-expressing dendritic cells form suppurative granulomas following Listeria monocytogenes infection. J Clin Invest (2006) 1.58
Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes? EMBO J (2013) 1.53
Functional characterization of cardiomyocytes derived from murine induced pluripotent stem cells in vitro. FASEB J (2009) 1.52
Cellular protein is the source of cross-priming antigen in vivo. Proc Natl Acad Sci U S A (2004) 1.51
Pathway for degradation of peptides generated by proteasomes: a key role for thimet oligopeptidase and other metallopeptidases. J Biol Chem (2004) 1.50
Cardiac cell therapies: the next generation. Cardiovasc Ther (2010) 1.47
Coordinate activation of autophagy and the proteasome pathway by FoxO transcription factor. Autophagy (2008) 1.47
The caspase-like sites of proteasomes, their substrate specificity, new inhibitors and substrates, and allosteric interactions with the trypsin-like sites. J Biol Chem (2003) 1.46
Nrdp1-mediated degradation of the gigantic IAP, BRUCE, is a novel pathway for triggering apoptosis. EMBO J (2004) 1.46
Mice completely lacking immunoproteasomes show major changes in antigen presentation. Nat Immunol (2011) 1.45
In vitro modeling of ryanodine receptor 2 dysfunction using human induced pluripotent stem cells. Cell Physiol Biochem (2011) 1.43
Both dendritic cells and macrophages can stimulate naive CD8 T cells in vivo to proliferate, develop effector function, and differentiate into memory cells. J Immunol (2005) 1.43
Structural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1. Nat Struct Mol Biol (2011) 1.42
Yeast adapt to near-freezing temperatures by STRE/Msn2,4-dependent induction of trehalose synthesis and certain molecular chaperones. Mol Cell (2004) 1.37
The cytosolic endopeptidase, thimet oligopeptidase, destroys antigenic peptides and limits the extent of MHC class I antigen presentation. Immunity (2003) 1.36
Identification of the cellular sensor that stimulates the inflammatory response to sterile cell death. J Immunol (2010) 1.36
S5a promotes protein degradation by blocking synthesis of nondegradable forked ubiquitin chains. EMBO J (2009) 1.36
Acetylation-mediated proteasomal degradation of core histones during DNA repair and spermatogenesis. Cell (2013) 1.35
KOC (K homology domain containing protein overexpressed in cancer): a novel molecular marker that distinguishes between benign and malignant lesions of the pancreas. Am J Surg Pathol (2005) 1.33
Cell death releases endogenous adjuvants that selectively enhance immune surveillance of particulate antigens. Eur J Immunol (2002) 1.33
Pluripotent stem cells escape from senescence-associated DNA methylation changes. Genome Res (2012) 1.32
Binding of hydrophobic peptides to several non-catalytic sites promotes peptide hydrolysis by all active sites of 20 S proteasomes. Evidence for peptide-induced channel opening in the alpha-rings. J Biol Chem (2002) 1.32
Myostatin/activin pathway antagonism: molecular basis and therapeutic potential. Int J Biochem Cell Biol (2013) 1.32
The active ClpP protease from M. tuberculosis is a complex composed of a heptameric ClpP1 and a ClpP2 ring. EMBO J (2012) 1.31
Combination of quantitative IMP3 and tumor stage: a new system to predict metastasis for patients with localized renal cell carcinomas. Clin Cancer Res (2008) 1.31
The specificity of trimming of MHC class I-presented peptides in the endoplasmic reticulum. J Immunol (2009) 1.30
Muscle wasting in aged, sarcopenic rats is associated with enhanced activity of the ubiquitin proteasome pathway. J Biol Chem (2010) 1.28
Mechanisms of skeletal muscle aging: insights from Drosophila and mammalian models. Dis Model Mech (2013) 1.28
Cutting edge: elimination of an endogenous adjuvant reduces the activation of CD8 T lymphocytes to transplanted cells and in an autoimmune diabetes model. J Immunol (2006) 1.26
Identification of a novel pool of extracellular pro-myostatin in skeletal muscle. J Biol Chem (2008) 1.23
The internal sequence of the peptide-substrate determines its N-terminus trimming by ERAP1. PLoS One (2008) 1.23
Getting to first base in proteasome assembly. Cell (2009) 1.22