Published in Nat Immunol on September 18, 2005
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Dendritic cells: caspases keep them young. Nat Immunol (2005) 0.76
The Cellular Apoptosis Susceptibility Protein (CAS) Promotes Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-induced Apoptosis and Cell Proliferation. J Biol Chem (2015) 0.76
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NOX2 controls phagosomal pH to regulate antigen processing during crosspresentation by dendritic cells. Cell (2006) 5.35
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Regulation of dendritic cell migration by CD74, the MHC class II-associated invariant chain. Science (2008) 2.88
Rab38 and Rab32 control post-Golgi trafficking of melanogenic enzymes. J Cell Biol (2006) 2.79
The Silver locus product Pmel17/gp100/Silv/ME20: controversial in name and in function. Pigment Cell Res (2005) 2.71
Rab27a regulates phagosomal pH and NADPH oxidase recruitment to dendritic cell phagosomes. Nat Cell Biol (2007) 2.69
Inhibition of retrograde transport protects mice from lethal ricin challenge. Cell (2010) 2.67
MHC class II proteins and disease: a structural perspective. Nat Rev Immunol (2006) 2.66
Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomes. Mol Biol Cell (2005) 2.56
The mature activating natural killer cell immunologic synapse is formed in distinct stages. Proc Natl Acad Sci U S A (2003) 2.56
Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7. J Cell Biol (2008) 2.56
BLOC-1 interacts with BLOC-2 and the AP-3 complex to facilitate protein trafficking on endosomes. Mol Biol Cell (2006) 2.37
ICAM-1 on exosomes from mature dendritic cells is critical for efficient naive T-cell priming. Blood (2005) 2.34
Wiskott-Aldrich syndrome protein is required for NK cell cytotoxicity and colocalizes with actin to NK cell-activating immunologic synapses. Proc Natl Acad Sci U S A (2002) 2.32
A lumenal domain-dependent pathway for sorting to intralumenal vesicles of multivesicular endosomes involved in organelle morphogenesis. Dev Cell (2006) 2.29
Secretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4. Nat Immunol (2007) 2.28
Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes. Nature (2008) 2.15
Proprotein convertase cleavage liberates a fibrillogenic fragment of a resident glycoprotein to initiate melanosome biogenesis. J Cell Biol (2003) 2.12
BLOC-1 is required for cargo-specific sorting from vacuolar early endosomes toward lysosome-related organelles. Mol Biol Cell (2006) 2.11
Multifocal structure of the T cell - dendritic cell synapse. Eur J Immunol (2005) 2.09
Diverse subpopulations of vesicles secreted by different intracellular mechanisms are present in exosome preparations obtained by differential ultracentrifugation. J Extracell Vesicles (2012) 2.06
ARF6 controls post-endocytic recycling through its downstream exocyst complex effector. J Cell Biol (2003) 2.02
IL-10 released by concomitant TLR2 stimulation blocks the induction of a subset of Th1 cytokines that are specifically induced by TLR4 or TLR3 in human dendritic cells. J Immunol (2004) 1.99
AP-1 and KIF13A coordinate endosomal sorting and positioning during melanosome biogenesis. J Cell Biol (2009) 1.99
MHC II in dendritic cells is targeted to lysosomes or T cell-induced exosomes via distinct multivesicular body pathways. Traffic (2009) 1.98
Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles. J Cell Sci (2013) 1.98
TGFbeta promotes conversion of CD16+ peripheral blood NK cells into CD16- NK cells with similarities to decidual NK cells. Proc Natl Acad Sci U S A (2007) 1.91
A dual mechanism controlling the localization and function of exocytic v-SNAREs. Proc Natl Acad Sci U S A (2003) 1.86
Exosomes as potent cell-free peptide-based vaccine. I. Dendritic cell-derived exosomes transfer functional MHC class I/peptide complexes to dendritic cells. J Immunol (2004) 1.86
Endosomes, exosomes and Trojan viruses. Trends Microbiol (2004) 1.84
Deficient natural killer cell cytotoxicity in patients with IKK-gamma/NEMO mutations. J Clin Invest (2002) 1.83
The tetraspanin CD63 regulates ESCRT-independent and -dependent endosomal sorting during melanogenesis. Dev Cell (2011) 1.82
Human decidual NK cells form immature activating synapses and are not cytotoxic. Proc Natl Acad Sci U S A (2005) 1.82
The retromer complex and clathrin define an early endosomal retrograde exit site. J Cell Sci (2007) 1.80
An essential function for beta-arrestin 2 in the inhibitory signaling of natural killer cells. Nat Immunol (2008) 1.79
CD1d-restricted NKT cells express a chemokine receptor profile indicative of Th1-type inflammatory homing cells. J Immunol (2003) 1.76
Viral evasion of natural killer cells. Nat Immunol (2002) 1.74
TI-VAMP/VAMP7 is required for optimal phagocytosis of opsonised particles in macrophages. EMBO J (2004) 1.71
NK cytotoxicity against CD4+ T cells during HIV-1 infection: a gp41 peptide induces the expression of an NKp44 ligand. Proc Natl Acad Sci U S A (2005) 1.67
CD151 accelerates breast cancer by regulating alpha 6 integrin function, signaling, and molecular organization. Cancer Res (2008) 1.64
Diaphanous-related formins are required for invadopodia formation and invasion of breast tumor cells. Cancer Res (2009) 1.63
T84-intestinal epithelial exosomes bear MHC class II/peptide complexes potentiating antigen presentation by dendritic cells. Gastroenterology (2007) 1.60
CD28-stimulated ERK2 phosphorylation is required for polarization of the microtubule organizing center and granules in YTS NK cells. Proc Natl Acad Sci U S A (2006) 1.59
Lysosome-related organelles: unusual compartments become mainstream. Curr Opin Cell Biol (2013) 1.59
Myosin IIA is required for cytolytic granule exocytosis in human NK cells. J Exp Med (2007) 1.59
Many NK cell receptors activate ERK2 and JNK1 to trigger microtubule organizing center and granule polarization and cytotoxicity. Proc Natl Acad Sci U S A (2007) 1.58
Separate functional domains of human MD-2 mediate Toll-like receptor 4-binding and lipopolysaccharide responsiveness. J Immunol (2003) 1.54
Retrovirus infection strongly enhances scrapie infectivity release in cell culture. EMBO J (2006) 1.53
ARF6 Interacts with JIP4 to control a motor switch mechanism regulating endosome traffic in cytokinesis. Curr Biol (2009) 1.52
Disulfide bond-mediated dimerization of HLA-G on the cell surface. Proc Natl Acad Sci U S A (2002) 1.52
Formation of a WIP-, WASp-, actin-, and myosin IIA-containing multiprotein complex in activated NK cells and its alteration by KIR inhibitory signaling. J Cell Biol (2006) 1.47
HLA-G homodimer-induced cytokine secretion through HLA-G receptors on human decidual macrophages and natural killer cells. Proc Natl Acad Sci U S A (2009) 1.41
Synchronization of secretory protein traffic in populations of cells. Nat Methods (2012) 1.41
Exosomes bearing HLA-DR1 molecules need dendritic cells to efficiently stimulate specific T cells. Int Immunol (2002) 1.41
Rab27A and its effector MyRIP link secretory granules to F-actin and control their motion towards release sites. J Cell Biol (2003) 1.40
Dual loss of ER export and endocytic signals with altered melanosome morphology in the silver mutation of Pmel17. Mol Biol Cell (2006) 1.37
Differential induction of IgE-mediated anaphylaxis after soluble vs. cell-bound tolerogenic peptide therapy of autoimmune encephalomyelitis. Proc Natl Acad Sci U S A (2005) 1.34
Mouse neuroblastoma cells release prion infectivity associated with exosomal vesicles. Biol Cell (2008) 1.33
CD1d and invariant NKT cells at the human maternal-fetal interface. Proc Natl Acad Sci U S A (2002) 1.30
Analysis of articulation between clathrin and retromer in retrograde sorting on early endosomes. Traffic (2009) 1.30
Crystal structure of HLA-DQ0602 that protects against type 1 diabetes and confers strong susceptibility to narcolepsy. Proc Natl Acad Sci U S A (2004) 1.29
N-terminal domains elicit formation of functional Pmel17 amyloid fibrils. J Biol Chem (2009) 1.28
The killer's kiss: the many functions of NK cell immunological synapses. Curr Opin Cell Biol (2008) 1.26
Exosomes: a bubble ride for prions? Traffic (2005) 1.24
Rab27b regulates mast cell granule dynamics and secretion. Traffic (2007) 1.22
Birbeck granules are subdomains of endosomal recycling compartment in human epidermal Langerhans cells, which form where Langerin accumulates. Mol Biol Cell (2002) 1.21
A minimal fragment of MUC1 mediates growth of cancer cells. PLoS One (2008) 1.19
Human immunodeficiency virus-1 Nef expression induces intracellular accumulation of multivesicular bodies and major histocompatibility complex class II complexes: potential role of phosphatidylinositol 3-kinase. Mol Biol Cell (2003) 1.18
Heterogeneity of TLR-induced responses in dendritic cells: from innate to adaptive immunity. Immunobiology (2004) 1.18
The actin-based motor protein myosin II regulates MHC class II trafficking and BCR-driven antigen presentation. J Cell Biol (2007) 1.17
Two unique human decidual macrophage populations. J Immunol (2011) 1.17
JNK MAP kinase activation is required for MTOC and granule polarization in NKG2D-mediated NK cell cytotoxicity. Proc Natl Acad Sci U S A (2008) 1.17
Premelanosome amyloid-like fibrils are composed of only golgi-processed forms of Pmel17 that have been proteolytically processed in endosomes. J Biol Chem (2007) 1.17
Monomeric recombinant MD-2 binds toll-like receptor 4 tightly and confers lipopolysaccharide responsiveness. J Biol Chem (2002) 1.17
Myosin 1b promotes the formation of post-Golgi carriers by regulating actin assembly and membrane remodelling at the trans-Golgi network. Nat Cell Biol (2011) 1.16
Dynamics of major histocompatibility complex class II compartments during B cell receptor-mediated cell activation. J Exp Med (2002) 1.16
MLL 5 protein forms intranuclear foci, and overexpression inhibits cell cycle progression. Proc Natl Acad Sci U S A (2004) 1.16
Nomenclature for Factors of the HLA System, 2004. Hum Immunol (2005) 1.14
Myosin Ib modulates the morphology and the protein transport within multi-vesicular sorting endosomes. J Cell Sci (2005) 1.13
Prions and exosomes: from PrPc trafficking to PrPsc propagation. Blood Cells Mol Dis (2005) 1.12
Protein complexes containing CYFIP/Sra/PIR121 coordinate Arf1 and Rac1 signalling during clathrin-AP-1-coated carrier biogenesis at the TGN. Nat Cell Biol (2010) 1.11
Contrasting effects of EWI proteins, integrins, and protein palmitoylation on cell surface CD9 organization. J Biol Chem (2006) 1.11
Rab6-interacting protein 1 links Rab6 and Rab11 function. Traffic (2007) 1.11