Published in J Immunol on December 01, 2011
Cytokine signaling: birth of a pathway. J Immunol (2011) 0.95
The JAK-STAT pathway at twenty. Immunity (2012) 4.41
Signal transduction and the control of gene expression. Science (2002) 4.38
Decay rates of human mRNAs: correlation with functional characteristics and sequence attributes. Genome Res (2003) 4.07
Identification of a nuclear Stat1 protein tyrosine phosphatase. Mol Cell Biol (2002) 3.57
Validating Stat3 in cancer therapy. Nat Med (2005) 2.96
UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity. EMBO J (2006) 2.84
PIAS1 selectively inhibits interferon-inducible genes and is important in innate immunity. Nat Immunol (2004) 2.52
Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha. Cell (2008) 2.25
Protein ISGylation modulates the JAK-STAT signaling pathway. Genes Dev (2003) 2.24
DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling. Development (2005) 2.08
Structural bases of unphosphorylated STAT1 association and receptor binding. Mol Cell (2005) 2.05
Proinflammatory stimuli induce IKKalpha-mediated phosphorylation of PIAS1 to restrict inflammation and immunity. Cell (2007) 1.89
Cyclin D1 is transcriptionally regulated by and required for transformation by activated signal transducer and activator of transcription 3. Cancer Res (2006) 1.69
Implications of an antiparallel dimeric structure of nonphosphorylated STAT1 for the activation-inactivation cycle. Proc Natl Acad Sci U S A (2005) 1.68
Dephosphorylation of phosphotyrosine on STAT1 dimers requires extensive spatial reorientation of the monomers facilitated by the N-terminal domain. Genes Dev (2006) 1.53
Regulation of protein tyrosine phosphatase 1B by sumoylation. Nat Cell Biol (2006) 1.40
A reinterpretation of the dimerization interface of the N-terminal domains of STATs. Protein Sci (2003) 1.39
Negative regulation of NF-kappaB signaling by PIAS1. Mol Cell Biol (2005) 1.38
Repression of Smad transcriptional activity by PIASy, an inhibitor of activated STAT. Proc Natl Acad Sci U S A (2003) 1.34
Independent and cooperative activation of chromosomal c-fos promoter by STAT3. J Biol Chem (2003) 1.32
Control of specificity and magnitude of NF-kappa B and STAT1-mediated gene activation through PIASy and PIAS1 cooperation. Proc Natl Acad Sci U S A (2007) 1.28
The ligase PIAS1 restricts natural regulatory T cell differentiation by epigenetic repression. Science (2010) 1.27
Dissociation time from DNA determines transcriptional function in a STAT1 linker mutant. J Biol Chem (2002) 1.26
STAT3-dependent enhanceosome assembly and disassembly: synergy with GR for full transcriptional increase of the alpha 2-macroglobulin gene. Genes Dev (2003) 1.22
Requirement of Ca2+ and CaMKII for Stat1 Ser-727 phosphorylation in response to IFN-gamma. Proc Natl Acad Sci U S A (2002) 1.21
PIASx is a MEF2 SUMO E3 ligase that promotes postsynaptic dendritic morphogenesis. J Neurosci (2007) 1.19
PIASy-mediated repression of the androgen receptor is independent of sumoylation. Oncogene (2004) 1.16
PIASx is a transcriptional co-repressor of signal transducer and activator of transcription 4. J Biol Chem (2003) 1.12
SnapShot: JAK-STAT signaling. Cell (2007) 1.10
Targeting the PIAS1 SUMO ligase pathway to control inflammation. Trends Pharmacol Sci (2008) 1.10
Distinct transcriptional activation functions of STAT1alpha and STAT1beta on DNA and chromatin templates. J Biol Chem (2003) 1.10
Regulation of the sumoylation system in gene expression. Curr Opin Cell Biol (2008) 1.09
Amino acid residues required for physical and cooperative transcriptional interaction of STAT3 and AP-1 proteins c-Jun and c-Fos. Mol Cell Biol (2007) 1.07
Negative regulation of STAT92E by an N-terminally truncated STAT protein derived from an alternative promoter site. Genes Dev (2002) 0.98
STAT92E is a positive regulator of Drosophila inhibitor of apoptosis 1 (DIAP/1) and protects against radiation-induced apoptosis. Proc Natl Acad Sci U S A (2008) 0.93
PIAS1 SUMO ligase regulates the self-renewal and differentiation of hematopoietic stem cells. EMBO J (2013) 0.89
Serpin B3/B4, activated by STAT3, promote survival of squamous carcinoma cells. Biochem Biophys Res Commun (2008) 0.86
Transformation fingerprint: induced STAT3-C, v-Src and Ha-Ras cause small initial changes but similar established profiles in mRNA. Oncogene (2004) 0.83
A Hopscotch-chromatin connection. Nat Genet (2006) 0.82
Systematic analysis of intrinsic factors affecting differential display. Biotechniques (2002) 0.79
Summon SUMO to wrestle with inflammation. Mol Cell (2009) 0.79
Reduced STAT3 activity in mice mimics clinical disease syndromes. Biochem Biophys Res Commun (2005) 0.78
Obituary: Hidesaburo Hanafusa (1929-2009). Nature (2009) 0.75